Clinical Trials on Side Effect in Canada

Total 4455 results

University Health Network, Toronto

Active, not recruiting

The Harmonized Interventions to Maintain Health Via Appropriate Risk Factor Modification and Lifestyle Changes in Pediatric, Adolescent and Young Adult Cancer Survivors Pilot Study (HIMALAYAS-P)

Heart Failure | Cancer | Cardiotoxicity

Canada
University Health Network, Toronto
Sunnybrook Health Sciences Centre; Unity Health Toronto; Mount Sinai Hospital... and other collaborators

Active, not recruiting

Statins for the Primary Prevention of Heart Failure in Patients Receiving Anthracycline Pilot Study (SPARE-HF)

Heart Failure | Cancer | Cardiotoxicity

Canada
Hospital Universitari de Bellvitge

Recruiting

ALND vs ART in Positive Sentinel Node After Neoadjuvant Therapy in Breast Cancer (ADARNAT)

Breast Cancer | Chemotherapy | Sentinel Lymph Node | Radiotherapy Side Effect | Axillary Lymph Nodes Dissection

Spain
University Health Network, Toronto
University of British Columbia; Alberta Health services; University of Alberta; Centre hospitalier de l'Université de Montréal (CHUM) and other collaborators

Recruiting

The HIMALAYAS Trial and Lifestyle Changes in Pediatric, Adolescent and Young Adult Cancer Survivors Study: A Multicentre Randomized Controlled Trial (HIMALAYAS)

Heart Failure | Cancer | Cardiotoxicity

Canada
Western University, Canada

Completed

The Kiss of Kindness Study II

Stress | Anxiety | Mood | Affect

Canada
University of Calgary

Recruiting

The ONE-MIND Study: Evaluating the Efficacy of Online Mindfulness-Based Cancer Recovery During Chemotherapy Treatment

Breast Cancer | Colorectal Cancer | Chemotherapy Effect

Canada
McGill University Health Centre/Research Institute...

Unknown

PhysioFlow to Detect Cardiotoxicity in Chemo (PULSE-ECCho)

Chemotherapy, Cancer, Cardiotoxicity, Physioflow

Canada
AHS Cancer Control Alberta
Cross Cancer Institute

Unknown

Study to See Whether Breath-Hold Techniques During RT Are Effective in Helping to Improve Sparing of the Heart

Breast Cancer | Adverse Effect of Radiation Therapy

Canada
St. Boniface Hospital

Unknown

Can Flaxseed Prevent Broken Hearts in Women With Breast Cancer Study? (CANFLAX)

Cardiotoxicity

Canada
University of Calgary
National Music Centre Studio Bell

Completed

Effects of Music Therapy on Mood, Pain, Patient and Staff Satisfaction on Adult Inpatient Neurological Units

Pain | Patient Satisfaction | Music Therapy | Affect | Inpatients

Canada
University of Manitoba

Completed

Long Term Comparison of Ultrasonic and Hand Instrumentation in the Maintenance of Peri-implant Tissues: A Randomized Clinical Trial

Determination of Clinical Effects | Presence of Inflammatory Cytokines | Patients Perception of Discomfort | Titanium Scalers | Ultrasonics

Canada
University of Manitoba

Terminated

Hemodynamic Effects of Low Dose Spinal Anesthesia for Cesarean Section

Personal Satisfaction | Hemodynamic Instability | Complications; Cesarean Section | Effects of; Anesthesia, Spinal and Epidural, in Pregnancy

Canada
University Health Network, Toronto
Canadian Institutes of Health Research (CIHR); University of Toronto

Active, not recruiting

Evaluation of Myocardial Changes During BReast Adenocarcinoma Therapy to Detect Cardiotoxicity Earlier With MRI (EMBRACE-MRI)

Breast Neoplasms

Canada
University of British Columbia

Completed

The Effect of Medication Review in High-risk Emergency Department Patients

Adverse Drug Events | Adverse Drug Reactions | Medication-related Problems

Canada
Western University, Canada
London Health Sciences Centre

Unknown

Diagnostic Test Validity of Structural Vertebral Endplate Defects

Defect of Vertebral Endplate (Disorder)

Canada
Nova Scotia Health Authority
Canadian Institutes of Health Research (CIHR); Canadian Cancer Society (CCS)

Recruiting

Exercise to Prevent AnthraCycline-based Cardio-Toxicity Study 2.0 (EXACT2) (EXACT 2)

Cardiovascular Diseases | Cardiotoxicity | Cancer, Breast

Canada
Ottawa Heart Institute Research Corporation
Canadian Institutes of Health Research (CIHR)

Terminated

Ability of L-carnitine to Prevent Heart Damage in Breast Cancer Patients Receiving Anthracycline Chemotherapy

Heart Failure

Canada
Mayo Clinic
St. Boniface Hospital; Lantheus Medical Imaging; The Asper Foundation

Completed

Early Detection of Broken Hearts in Cancer Patients (ASPER)

Cardiotoxicity

United States, Canada
University of Calgary
Alberta Health services; Hotchkiss Brain Institute, University of Calgary

Recruiting

Pharmacogenetics of Antidepressant-Induced Disinhibition (PGx-AID)

Obsessive-Compulsive Disorder | Anxiety Disorders | Major Depressive Disorder | Antidepressant Drug Adverse Reaction

Canada
University Health Network, Toronto
Canadian Institutes of Health Research (CIHR); MSH-UHN AMO Innovation Fund

Terminated

Efficacy of Cardio-Oncology Rehabilitation Exercise for Women With Breast Cancer and Treatment Related Cardiotoxicity (CORE)

Breast Cancer | Heart Failure, Systolic | Left Ventricular Dysfunction

Canada
Unity Health Toronto
Hoffmann-La Roche

Unknown

Assessment of Cardiotoxicity by Cardiac Magnetic Resonance (CMR) in Breast Cancer Patients Receiving Trastuzumab

Stage I-IV Breast Cancer (Neo-adjuvant, Adjuvant, Locally Advanced and Metastatic)

Canada
Innovaderm Research Inc.

Completed

Effect of RANKL Inhibition on UV-induced Immunosuppression

Hypersensitivity, Delayed | Immunosuppression | Ultraviolet Rays | Immune Tolerance/Drug Effects

Canada
Baskent University Ankara Hospital

Completed

Dexmedetomidine and Remifentanil in NORA

Comparison of the Effects of Remifentanil and Dexmedetomidine

Turkey
J.J.Swen
Karolinska Institutet; Medical University of Vienna; Uppsala University; St. Antonius... and other collaborators

Completed

PREemptive Pharmacogenomic Testing for Preventing Adverse Drug REactions (PREPARE)

Adverse Drug Reaction

Austria, Netherlands, Italy, Greece, Slovenia, Spain, United Kingdom
Massachusetts General Hospital
Dana-Farber Cancer Institute; Brigham and Women's Hospital

Completed

STOP-CA (Statins TO Prevent the Cardiotoxicity From Anthracyclines)

Heart Failure

United States, Canada
AHS Cancer Control Alberta

Terminated

Novel Surrogate Markers as Predictors of Radiation Toxicity in Breast Cancer Patients Undergoing Helical Tomotherapy Compared to Standard Radiation Therapy

Cardiac Toxicity | Genetic Markers | Breast and Skin Motion

Canada
University Health Network, Toronto

Unknown

Does Aspirin Have a Protective Role Against Chemotherapeutically Induced Ototoxicity?

Hearing Loss | Ototoxicity

Canada
Universidad de Granada

Enrolling by invitation

Telehealth Program to Prevent Cancer and Chemotherapy-related Cognitive Impairment.

Breast Neoplasms

Spain
Montreal Heart Institute

Completed

Characterization of Myocardial Blood Flow During Heat Exposure (PET-Heat)

Coronary Artery Disease | Healthy | Aging | Hot Weather; Adverse Effect

Canada
McGill University Health Centre/Research Institute...

Unknown

Transtympanic Ringer's Lactate for the Prevention of Cisplatin Ototoxicity

Hearing Loss

Canada
Nova Scotia Health Authority

Completed

Exercise to Prevent AnthrCycline-based Cardio-Toxicity Study (EXACT)

Neoplasms | Inflammation | Heart; Disease, Functional

Canada
CHU de Quebec-Universite Laval
Laval University; Université de Montréal

Completed

Suture of UTerus and Ultrasound Repair Evaluation (SUTURE)

Uterine Scar Defect

Canada
Sunnybrook Health Sciences Centre

Recruiting

Efficacy of Sodium Thiosulfate and Mannitol in Reducing Ototoxicity in Adult Patients Receiving Cisplatin Chemotherapy

Ototoxic Hearing Loss

Canada
Philippe Bégin
The Hospital for Sick Children; Centre de recherche du Centre hospitalier universitaire... and other collaborators

Recruiting

Omalizumab to Accelerate a Symptom-driven Multi-food OIT (BOOM)

Immunotherapy | Physiological Effects of Drugs | Food IgE-mediated Allergy | Omalizumab

Canada
Sunnybrook Health Sciences Centre
London Regional Cancer Program, Canada; Toronto Sunnybrook Regional Cancer...

Recruiting

Intratympanic N-Acetylcysteine for Prevention of Cisplatin-induced Ototoxicity.

Ototoxic Hearing Loss

Canada
The Hospital for Sick Children
Canadian Institutes of Health Research (CIHR); London Health Sciences Centre; Children's Hospital of Eastern Ontario and other collaborators

Completed

Preventing Cardiac Sequelae in Pediatric Cancer Survivors (PCS2)

Anthracycline-induced Cardiotoxicity

United States, Canada
University of Waterloo
Wilderness Medical Society

Completed

Effect of Acetazolamide and Methazolamide on Hypoxic Exercise Performance

High Altitude Effects

Canada
AHS Cancer Control Alberta
Cross Cancer Institute

Completed

A Prospective Study of Acute Cardiovascular Effects of First-line Sunitinib in Metastatic Renal Cell Carcinoma Patients (SUnitinib Prospective CardiovasculaR Effect) (SUPER)

Heart Failure | Renal Cell Carcinoma | Hypertension | Cardiotoxicity

Canada
University of British Columbia
Johnson & Johnson Consumer Inc. (J&JCI); Genome British Columbia

Active, not recruiting

Epigenetic Health Benefits of Budesonide (Project Ace)

Environmental Exposure | Epigenetic Effects of Intranasal Steroids

Canada
University Health Network, Toronto

Completed

Put a Face to a Name (Part A): The Effects of Photographic Aids on Patient Satisfaction, Clinician Communication, and Quality of Care (Face2Name)

Effects of Photographic Aids (Photos of Faces) on Patient Recall of Their Clinical Care Team | Effects of Photographic Aids (Photos of Faces) on Clinician-patient Communication | Effects of Photographic Aids (Photos of Faces) on Overall Patient Satisfaction

Canada
Ángel Becerra
University of Las Palmas de Gran Canaria

Completed

Perioperative Hypothermia in Patients Submitted to Laparoscopic Urological Surgery

Postoperative Complications | Surgical Site Infection | Hypothermia; Anesthesia | Temperature Change, Body | Anesthesia; Adverse Effect | Peroperative Complication

Spain
Lawson Health Research Institute
Canadian Institutes of Health Research (CIHR)

Unknown

Detecting Radiation-Induced Cardiac Toxicity After Non-Small Cell Lung Cancer Radiotherapy (RICT-LUNG)

Non-small Cell Lung Cancer | Radiation Toxicity

Canada
Montreal Heart Institute
AstraZeneca

Recruiting

Identification and Evaluation of Patients at Risk of Developing Cardiotoxicity After Receiving Chemotherapy for Breast Cancer, Lymphoma or Leukemia (CarChem)

Lymphoma | Leukemia | Breast Cancer

Canada
McMaster University
Geistlich Pharma AG

Recruiting

AMIC Compared With Microfracture for Focal Articular Cartilage Damage of the Hip (REPAIR)

Hip Arthroscopy | Articular Cartilage Defect | Microfractures

Canada
Partner Therapeutics, Inc.

Completed

Study to Evaluate Pharmacokinetics, Pharmacodynamics, and Safety of Sargramostim Administered Subcutaneously, Intravenously, or by Inhalation

Drug Kinetics | Drug Effects on Physiology

Canada
McGill University

Active, not recruiting

The Effects of Walking in Nature (vs. an Urban Setting) on the Wellbeing of Postsecondary Students.

Stress | Sleep | Depressive Symptoms | Anxiety Disorders and Symptoms | Affect | Non-suicidal Self-injury | Wellness, Psychological

Canada
Nova Scotia Health Authority

Completed

A Study to Evaluate the Safety of Augment™ Bone Graft

Defect of Articular Cartilage

Canada
Centre hospitalier de l'Université de Montréal...
CHU de Quebec-Universite Laval; Centre de recherche du Centre hospitalier universitaire... and other collaborators

Completed

SURgical Outcomes in COvid Patients - the SUROCO Multicenter Cohort Study (COVID-19) (SUROCO)

Postoperative Complications | Covid-19 | Surgery | SARS-CoV2 | Surgical Procedure; Complications, Late Effect of Complications

Canada
Laval University
Bristol-Myers Squibb; Sanofi

Completed

Clopidogrel For the Prevention of New Onset Migraine Headache Following Transcatheter Closure of Atrial Septal Defects (CANOA)

Migraine

Canada
Dr. Negrin University Hospital

Completed

Postoperative Pain in Scheduled Craniotomy

Pain, Postoperative | Anxiety | Craniotomy | Adverse Effect

Spain

Clinical Trials on Side Effect in Canada

Sponsors and Collaborators

Medical Conditions

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CROs in Tanzania

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