Clinical Trials on Single-Gene Defects in United States
Total 3347 results
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Peerbridge Health, IncCompletedAtrial Fibrillation | Premature Atrial and Ventricular Beats | Conduction Defects | Normal Sinus RhythmUnited States
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University of UtahTerminatedPrimary Myelofibrosis | Anemia | Thrombocytopenia | Plasma Cell Myeloma | Recurrent Plasma Cell Myeloma | IDH2 Gene Mutation | IDH1 Gene Mutation | Secondary Myelofibrosis | ASXL1 Gene Mutation | EZH2 Gene MutationUnited States
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Scripps Translational Science InstituteNavigenics, Inc.; Affymetrix, Inc.Active, not recruiting
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SeqirusCompleted
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Quadram Institute BioscienceCompletedSingle Nucleotide PolymorphismUnited Kingdom
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M.D. Anderson Cancer CenterNational Cancer Institute (NCI)Active, not recruitingBreast Carcinoma | Fallopian Tube Carcinoma | Endometrial Carcinoma | Ovarian Carcinoma | Primary Peritoneal Carcinoma | Deleterious CDH1 Gene Mutation | Deleterious DICER1 Gene Mutation | Deleterious SMARCA4 Gene Mutation | Deleterious STK11 Gene MutationUnited States
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Children's Mercy Hospital Kansas CityCompletedHeart Failure | Pulmonary Hypertension | Single VentricleUnited States
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National Human Genome Research Institute (NHGRI)CompletedCongenital Abnormalities | Birth Defects | Congenital DefectsUnited States
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Mayo ClinicWithdrawnForamen Ovale, PatentUnited States
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HutchmedActive, not recruitingIsocitrate Dehydrogenase Gene MutationUnited States, Spain
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Vericel CorporationCompletedArticular Cartilage DefectNetherlands, Norway, France, Czechia, Sweden, Poland, United Kingdom
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Retropsoas Technologies, LLCNot yet recruitingUndergoing a Single-level or Two-level TLIF SurgeryUnited States
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University of OregonRecruiting
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University of OregonEnrolling by invitationPatent Foramen OvaleUnited States
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Nicole Fram M.D.CompletedCataract Senile | Anterior Chamber Inflammation | Ocular Pain | Corneal Edema | Corneal Defect | Penetrating KeratoPlasty | Nuclear Cataract | Cortical CataractUnited States
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Memorial Sloan Kettering Cancer CenterCompletedBreast Cancer | Metastatic Breast Cancer | Breast Cancer Stage IV | Solid Carcinoma | HER2-negative Breast Cancer | MEK1 Gene Mutation | MEK2 Gene MutationUnited States
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University of Maryland, BaltimoreCompletedRobotic Surgery | Renal Transplant Donor of Left Kidney | Donor Nephrectomy | Single-portUnited States
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Emory UniversityCompletedDouble Outlet Right VentricleUnited States
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Thomas Jefferson UniversityCompletedStage IVA Lung Cancer AJCC v8 | Stage IVB Lung Cancer AJCC v8 | Lung Non-Small Cell Carcinoma | Stage IV Lung Cancer AJCC v8 | Health Care Provider | Activating ALK Gene Mutation Negative | Activating EGFR Gene Mutation Negative | Activating ROS1 Gene Mutation NegativeUnited States
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University of UlsterBelfast Health and Social Care TrustCompletedCongenital Heart Disease | Congenital Heart Defect | Adult Congenital Heart DiseaseUnited Kingdom
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Boston Children's HospitalUnited States Department of DefenseCompletedChildren | Neurodevelopmental Disorders | Executive Function | Working Memory | Congenital Heart Defect | Infant Open Heart SurgeryUnited States
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Nationwide Children's HospitalAmerican Heart AssociationCompleted
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National Heart, Lung, and Blood Institute (NHLBI)Completed
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National Center for Research Resources (NCRR)Completed
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Emory UniversityCompletedPrimary Condition: Heart Defects Requiring Surgery With CPBUnited States
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University of Texas at AustinDell Children's Medical Center of Central TexasRecruitingHeart Defects, CongenitalUnited States
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Boston Children's HospitalCompleted
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PECA LabsRecruitingTransposition of Great Vessels | Pulmonary Atresia | Pulmonary Stenosis | Tetrology of Fallot | Truncus Arteriosus | Ross ProcedureUnited States
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University of California, IrvineWithdrawn
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PfizerMedivation, Inc.; Myriad Genetic Laboratories, Inc.TerminatedBreast Neoplasms | BRCA 1 Gene Mutation | BRCA 2 Gene MutationUnited States, Spain, United Kingdom, Germany, France
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Brigham and Women's HospitalNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)CompletedCircadian Rhythm | Melatonin | Glucose | GenesUnited States
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John M CostelloAmerican Heart AssociationTerminatedHeart Defects, CongenitalUnited States
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Children's Hospital Medical Center, CincinnatiAmerican Society of Anesthesiologists; International Anesthesia Research Society...Completed
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Bernhard KuhnUniversity of PittsburghRecruitingTetralogy of Fallot | Double Outlet Right VentricleUnited States
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Duke UniversityWithdrawnHeart Defects, CongenitalUnited States
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Jonsson Comprehensive Cancer CenterAstraZenecaActive, not recruitingGlioblastoma | Recurrent Glioblastoma | EGFR Gene Mutation | Supratentorial Glioblastoma | EGFR Gene Amplification | TP53 wt AlleleUnited States
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Gabi SmartCareCompletedCardiovascular Diseases | Respiratory Disease | Cardiac Disease | Congenital Cardiac Defect | Premature Infant Disease | Chronic Respiratory Disease | Chronic Cardiopulmonary DiseaseUnited States, Belgium
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QED Therapeutics, Inc.Helsinn Healthcare SATerminatedFGFR2 Gene Mutation | Advanced CholangiocarcinomaKorea, Republic of, United States, Belgium, Spain, Taiwan, China, United Kingdom, France, Canada, Germany, Thailand, Italy, Portugal, Australia, Puerto Rico
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Boston Children's HospitalCompletedCongenital Heart DefectsUnited States
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Emory UniversityTerminatedCongenital Heart DefectsUnited States
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Boston Children's HospitalCompletedCongenital Heart DefectsUnited States
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Boston Children's HospitalTerminatedHeart Defects, Congenital | Cardiopulmonary BypassUnited States
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Vanderbilt UniversityNational Heart, Lung, and Blood Institute (NHLBI)CompletedHeart Diseases | Cardiovascular Diseases | Heart Defects, CongenitalUnited States
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OrthoCarolina Research Institute, Inc.Charlotte Orthopedic HospitalSuspendedSingle Level Lumbar Decompression and Fusion Spine SurgeryUnited States
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Taiho Oncology, Inc.Active, not recruitingAdvanced Cholangiocarcinoma | FGFR2 Gene RearrangementsUnited States, Spain, United Kingdom, Australia, Taiwan, Italy, France, Korea, Republic of, Belgium, Japan, Thailand, Germany, Brazil, Peru, Portugal, Argentina, Hong Kong, Mexico, Netherlands, Poland
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University of MichiganBioHorizons, Inc.CompletedDental Implant Soft Tissue Defects in the Anterior MaxillaUnited States
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Emory UniversityChildren's Healthcare of AtlantaCompletedCardiopulmonary Bypass | Congenital Heart DefectsUnited States
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Children's Hospital Medical Center, CincinnatiRecruitingNeurofibromatosis 1 | Noonan Syndrome | Legius Syndrome | Cardiofaciocutaneous Syndrome | Costello Syndrome | SYNGAP1-Related Intellectual Disability | DLG4 | RAS Mutation | Noonan Syndrome With Multiple Lentigines | Noonan Neurofibromatosis Syndrome | Smith-Kingsmore Syndrome | MTOR Gene Mutation | GATOR-1 Gene... and other conditionsUnited States
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Washington University School of MedicineNational Heart, Lung, and Blood Institute (NHLBI); Medical College of Wisconsin and other collaboratorsCompletedSickle Cell DiseaseUnited States