Clinical Trials on Sitting Position in South Africa

Total 635 results

Medecins Sans Frontieres, Netherlands
London School of Hygiene and Tropical Medicine; University College, London; University... and other collaborators

Completed

Pragmatic Clinical Trial for a More Effective Concise and Less Toxic MDR-TB Treatment Regimen(s) (TB-PRACTECAL)

Tuberculosis, Pulmonary | Tuberculosis, Multidrug-Resistant | Extensively Drug-Resistant Tuberculosis

Belarus, South Africa, Uzbekistan
International AIDS Vaccine Initiative
University of Cape Town Lung Institute; European and Developing Countries Clinical... and other collaborators

Active, not recruiting

Study to Evaluate H56:IC31 in Preventing Rate of TB Recurrence

Tuberculosis, Pulmonary

South Africa, Tanzania
Michael Hoelscher
Radboud University Medical Center; University College, London; University of...

Recruiting

PanACEA - STEP2C -01

Pulmonary Tuberculosis | Other Specified Pulmonary Tuberculosis

Gabon, South Africa, Tanzania, Malawi, Uganda, Mozambique
International Maternal Pediatric Adolescent AIDS...
National Institute of Allergy and Infectious Diseases (NIAID); Eunice Kennedy... and other collaborators

Not yet recruiting

Safety and Immunogenicity of VPM1002 Vaccination or BCG Revaccination Against TB in Pre-Adolescents Living With and Without HIV in South Africa

HIV Infections | Tuberculosis

South Africa
The Aurum Institute NPC
Johns Hopkins University

Recruiting

Comparing Treatment Completion Of Daily Rifapentine & Isoniazid For One Month (1HP) To Weekly High Dose Rifapentine & Isoniazid For 3 Months (3HP) In Persons Living With HIV and in Household Contacts of Recently Diagnosed Tuberculosis Patients (1 to 3)

Tuberculosis | HIV Seropositivity | Household Contact

South Africa, India, Indonesia, Mozambique
National Institute of Allergy and Infectious Diseases...
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Active, not recruiting

Evaluating the Pharmacokinetics, Safety, and Tolerability of Bedaquiline in Infants, Children, and Adolescents With Multidrug-Resistant Tuberculosis, Living With or Without HIV

HIV | Tuberculosis

Haiti, India, South Africa
ANRS, Emerging Infectious Diseases
European and Developing Countries Clinical Trials Partnership (EDCTP); European...

Recruiting

Intensified Tuberculosis Treatment to Reduce the Mortality of Patients With Tuberculous Meningitis (INTENSE-TBM)

Tuberculous Meningitis

Côte D'Ivoire, Madagascar, South Africa, Uganda
Medecins Sans Frontieres, Netherlands
London School of Hygiene and Tropical Medicine; University of Liverpool; Ministry... and other collaborators

Completed

Economic Evaluation of New MDR TB Regimens (PRACTECAL-EE)

Multi-drug Resistant Tuberculosis | Pulmonary Tuberculoses | Extensively Drug-Resistant Tuberculosis

Belarus, South Africa, Uzbekistan
Médecins Sans Frontières, France
Harvard Medical School (HMS and HSDM); Institute of Tropical Medicine, Belgium and other collaborators

Completed

Evaluating Newly Approved Drugs for Multidrug-resistant TB (endTB)

Tuberculosis, Multidrug-Resistant | Infection, Bacterial | Pulmonary Tuberculoses

Pakistan, Georgia, India, Kazakhstan, Lesotho, Peru, South Africa
HIV Vaccine Trials Network
National Institute of Allergy and Infectious Diseases (NIAID); Biofabri, S.L

Recruiting

Evaluating the Safety and Immunogenicity of MTBVAC in Adolescents and Adults Living With and Without HIV in South Africa (HVTN605A5421)

Tuberculosis | HIV I Infection

South Africa
Prof Gerhard Walzl
London School of Hygiene and Tropical Medicine; Makerere University; Leiden University... and other collaborators

Completed

Evaluation of Host Biomarker-based Point-of-care Tests for Targeted Screening for Active TB (ScreenTB)

Pulmonary Tuberculosis

United Kingdom, Uganda, Ethiopia, Gambia, Germany, Namibia, Netherlands, South Africa
Arthrex, Inc.

Recruiting

Evaluate the Continued Safety and Performance of the Foot and Ankle Products

Hyperpronated Foot | Reconstruction Surgeries of the Foot | Fixation of Fractures and Fusion (Bunionectomy Osteotomies) of the Foot/Ankle | Fixation of Small Bone Fragments of the Foot/Ankle | Lisfranc Arthrodesis | Mono or Bi-cortical Osteotomies in the Forefoot | First Metatarsophalangeal Arthrodesis and other conditions

Germany, United States, South Africa
Bill & Melinda Gates Medical Research Institute
Wellcome Trust

Completed

Safety and Immunogenicity of a Mycobacterium Tuberculosis Vaccine M72/AS01E in Participants With Well-controlled HIV (MESA-TB)

Human Immunodeficiency Virus

South Africa
IUATLD, Inc
Medical Research Council; Institute of Tropical Medicine, Belgium; Liverpool... and other collaborators

Completed

The Evaluation of a Standard Treatment Regimen of Anti-tuberculosis Drugs for Patients With MDR-TB (STREAM)

MDR-TB

Ethiopia, Georgia, India, Moldova, Republic of, Mongolia, South Africa, Uganda
Foundation for Innovative New Diagnostics, Switzerland
Swiss Tropical & Public Health Institute; University of Cape Town; The HIV Netherlands... and other collaborators

Completed

FujiLAM Prospective Evaluation Trial

Diagnosis of Tuberculosis in People Living With HIV

Malawi, South Africa, Tanzania, Thailand, Uganda, Vietnam, Zambia
AIDS Clinical Trials Group
National Institute of Allergy and Infectious Diseases (NIAID)

Terminated

Rifampin-Based Tuberculosis Treatment Versus Rifabutin-Based Tuberculosis Treatment in Persons With HIV

HIV Infection | Tuberculosis

Peru, Brazil, South Africa, Haiti, Kenya
NovaBay Pharmaceuticals, Inc.

Completed

Vehicle Controlled Efficacy and Safety Study of Two Dose Regimens of CD07223 1.5% Topical Gel in Impetigo

Impetigo

United States, South Africa
University of California, San Francisco
Johns Hopkins University

Not yet recruiting

Program for Rifampicin-Resistant Disease With Stratified Medicine for Tuberculosis (PRISM-TB)

Tuberculosis, Pulmonary | Tuberculosis, Multidrug-Resistant | Tuberculosis, MDR

Peru, Vietnam, Moldova, Republic of, Mongolia, Pakistan, Philippines, South Africa
Ferrer Internacional S.A.

Completed

Efficacy and Safety of Ozenoxacin 1% Cream Versus Placebo in the Treatment of Patients With Impetigo

Impetigo

Germany, South Africa
Serum Institute of India Pvt. Ltd.
Vakzine Projekt Management GmbH

Active, not recruiting

Evaluation of Efficacy and Safety of VPM1002 in Comparison to BCG in Prevention of Tb Infection in Infants (VPM1002)

Mycobacterium Tuberculosis Infection

Gabon, Kenya, South Africa, Tanzania, Uganda
AIDS Clinical Trials Group
National Institute of Allergy and Infectious Diseases (NIAID); National Institute...

Completed

Observational Study of Specificity of Mycobacterium Tuberculosis Screening and Diagnostics in HIV-Infected Individuals

HIV Infections | Tuberculosis

Peru, South Africa, Botswana, Brazil, India, Malawi, Zimbabwe
Merck Sharp & Dohme LLC

Completed

A Study to Evaluate the Safety, Tolerability, and Immunogenicity of V114 Followed by PNEUMOVAX™23 in Adults Infected With Human Immunodeficiency Virus (HIV) (V114-018) (PNEU-WAY)

Pneumococcal Infections

United States, France, Peru, South Africa, Thailand
National Institute of Allergy and Infectious Diseases...

Completed

Evaluating the Safety of Immediate Versus Deferred Isoniazid Preventive Therapy Among HIV-Infected Pregnant Women

HIV Infections | Tuberculosis

Haiti, South Africa, Thailand, Tanzania, Botswana, Zimbabwe, India, Uganda
McGill University
Canadian Institutes of Health Research (CIHR)

Completed

Rifampin Versus Isoniazid for the Treatment of Latent Tuberculosis Infection in Children (P4v9)

Latent Tuberculosis Infection

Canada, Australia, Benin, Brazil, Ghana, Guinea, Indonesia
Hoffmann-La Roche

Completed

A Study of Continued Treatment Among Participants Who Have Responded to Peginterferon Alfa-2a (Pegasys®) or Recombinant Interferon Alfa-2a (Roferon-A®) in Prior Clinical Studies

Renal Cell Carcinoma | Chronic Myelogenous Leukemia | Malignant Melanoma

Canada, India, Bulgaria, Russian Federation, Spain, South Africa, Slovakia
Janssen Infectious Diseases BVBA

Completed

TMC207-TiDP13-C208: Anti-bacterial Activity, Safety, and Tolerability of TMC207 in Participants With Multi-drug Resistant Mycobacterium Tuberculosis (MDR-TB).

Tuberculosis

South Africa, Peru, Latvia, Philippines, Russian Federation, Thailand, Brazil, India
Centers for Disease Control and Prevention
British Medical Research Council

Recruiting

Assessment of the Safety, Tolerability, and Effectiveness of Rifapentine Given Daily for LTBI (ASTERoiD)

Latent Tuberculosis

Australia, United States, Canada, South Africa
Global Alliance for TB Drug Development

Completed

Various Doses and Durations of Linezolid Plus Bedaquiline & Pretomanid in Participants With Drug Resistant Tuberculosis (ZeNix)

Tuberculosis | Tuberculosis, Pulmonary | Tuberculosis, Multidrug-Resistant | Extensively Drug-Resistant Tuberculosis | Tuberculosis, MDR | XDR-TB | Pre-XDR-TB

South Africa, Russian Federation, Georgia, Moldova, Republic of
Partners in Health
Harvard Medical School (HMS and HSDM); Epicentre; Interactive Research and Development and other collaborators

Completed

Expand New Drugs for TB [endTB]

Tuberculosis, Multidrug-Resistant

Georgia, Armenia, Bangladesh, Belarus, Ethiopia, Indonesia, Kazakhstan, Kenya, Kyrgyzstan, Lesotho, Myanmar, Pakistan, Peru, South Africa
Centers for Disease Control and Prevention
US Department of Veterans Affairs

Completed

TBTC NAA Study: Pilot Study of Surrogate Markers for Outcome of TB Treatment

Tuberculosis

Uganda, United States, Canada, South Africa
University Medical Center Groningen

Unknown

Feasibility of Centralized Therapeutic Drug Monitoring of Fluoroquinolones in Multi-Drug Resistant Tuberculosis Patients (PERFECT)

Tuberculosis, Multidrug-Resistant

Sweden, United Kingdom, Australia, Belarus, Brazil, Greece, Italy, Latvia, Mexico, Netherlands, Portugal, South Africa, Tanzania
Centers for Disease Control and Prevention

Completed

Study 33: Adherence to Latent Tuberculosis Infection Treatment 3HP SAT Versus 3HP DOT (iAdhere)

Latent Tuberculosis Infection

United States, China, South Africa, Spain
Johns Hopkins University
National Institute of Allergy and Infectious Diseases (NIAID); National Institutes... and other collaborators

Active, not recruiting

A Nurse Case Management Intervention to Improve MDR-TB/HIV Co-Infection Outcomes

HIV | MDR-TB

South Africa
Otsuka Pharmaceutical Development & Commercialization...

Completed

Safety and Efficacy Trial of Delamanid for 6 Months in Participants With Multidrug-resistant Tuberculosis

Multidrug-resistant Tuberculosis

South Africa, Estonia, Philippines, Peru, Lithuania, Latvia, Moldova, Republic of
Pfizer

Completed

Trial To Evaluate The Safety, Tolerability, And Immunogenicity Of A Multivalent Group B Streptococcus Vaccine In Healthy Nonpregnant Women And Pregnant Women And Their Infants

Group B Streptococcus Infections

United States, South Africa, United Kingdom
Novartis Pharmaceuticals

Terminated

Study to Assess Efficacy and Safety of Nilotinib 300mg Twice Daily in Patients With Philadelphia Positive Chronic Myeloid Leukaemia (CML) in Chronic Phase Who Are Intolerant to Prior Tyrosine Kinase Inhibitors. (ENESTswift)

Philidelphia Positive Chronic Myeloid Leukaemia

Australia
GPN Vaccines

Recruiting

Extension Safety and Immunogenicity Study of GPNV-001

Pneumococcal Infections

Australia
GPN Vaccines

Recruiting

Safety, Tolerability and Immunogenicity of an Inactivated Whole-cell Pneumococcal Vaccine Gamma-PN3.

Pneumococcal Infections

Australia
Holdsworth House Medical Practice

Completed

RETRIeVE: ReversE TranscRiptase Inhibitor hiV Practice

HIV Positive

Australia
Molecular Templates, Inc.

Terminated

Study of MT-5111 in HER2-positive Solid Tumors (MT-5111)

HER2-positive Solid Cancers

United States, Australia, New Zealand
Pfizer

Completed

Evaluation of a Single Vaccination With a 4-Antigen Staphylococcus Aureus Vaccine (SA4Ag) in Healthy Adults Aged 18 to <65 Years

Staphylococcal Infections

United States
Global Alliance for TB Drug Development

Recruiting

Phase 2 Trial Assessing TBAJ876 or Bedaquiline, With Pretomanid and Linezolid in Adults With Drug-sensitive Pulmonary Tuberculosis

Drug Sensitive Tuberculosis | Pulmonary Tuberculosis | Pulmonary TB

Philippines, South Africa, Tanzania, Georgia, Uganda
Pfizer

Completed

Trial to Evaluate the Safety and Immunogenicity of a Multivalent Pneumococcal Conjugate Vaccine in Adults 60 Through 64 Years of Age

Pneumococcal Infections

United States
St Vincent's Hospital

Recruiting

A Window of Opportunity Study of Pre-operative Endocrine Therapy With and Without Prometrium in Postmenopausal Women With Early Stage Breast Hormone Receptor Positive (HR+) Human Epidermal Receptor 2 Negative (HER2-) Breast Cancer. (WinPro)

Hormone Receptor Positive Tumor | Early-stage Breast Cancer

Australia
AIDS Clinical Trials Group
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Pharmacokinetic Study to Evaluate Double-Dose Levonorgestrel Emergency Contraception in Combination With Efavirenz-Based Antiretroviral Therapy or Rifampicin-Containing Anti-Tuberculosis Therapy

HIV Infections | Tuberculosis

United States, South Africa, Malawi, Brazil, Kenya, Thailand, Botswana
D3 Bio (Wuxi) Co., Ltd

Recruiting

A Study of D3L-001 as Monotherapy in Subjects With HER2-Positive Advanced Solid Tumors

HER-2 Positive Advanced Solid Tumors

Australia, United States, China
The Hospital for Sick Children
Bristol-Myers Squibb

Terminated

Pilot Study of Nivolumab in Pediatric Patients With Hypermutant Cancers

Refractory or Recurrent Hypermutated Malignancies | Biallelic Mismatch Repair Deficiency (bMMRD) Positive Patients

United States, France, Canada, Australia, Israel
Janssen Infectious Diseases BVBA

Completed

To Evaluate the Safety, Tolerability, and Efficacy of TMC207 as Part of an Individualized Multi-drug Resistant Tuberculosis (MDR-TB) Treatment Regimen in Participants With Sputum Smear-positive Pulmonary MDR-TB.

Tuberculosis

China, Ukraine, Korea, Republic of, Peru, Estonia, Kenya, Latvia, Philippines, Russian Federation, South Africa, Thailand, Turkey
Medecins Sans Frontieres, Spain

Completed

Evaluation of Point-of-care Ultrasound in Children From 6 Months to 15 Years With Presumptive Tuberculosis

Tuberculosis

Guinea-Bissau, South Sudan
City of Hope Medical Center
National Cancer Institute (NCI); Merck Sharp & Dohme LLC

Completed

Pembrolizumab and Doxorubicin Hydrochloride or Anti-Estrogen Therapy in Treating Patients With Triple-Negative or Hormone Receptor-Positive Metastatic Breast Cancer

Stage IV Breast Cancer | Estrogen Receptor Negative | Estrogen Receptor Positive | HER2/Neu Negative | Progesterone Receptor Negative | Progesterone Receptor Positive | Triple-Negative Breast Carcinoma

United States

Clinical Trials on Sitting Position in South Africa

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