Clinical Trials on Small Vessel Disease of Diabetes Mellitus

Total 18719 results

Medical University of Warsaw

Completed

Randomized Comparison of Laparoscopic Sleeve Gastrectomy and Gastric Bypass for Morbid Obesity

Hypertension | Diabetes Mellitus | Dyslipidemia | Morbid Obesity | Metabolic Syndrome X

Poland
Vanderbilt University
National Institute of Allergy and Infectious Diseases (NIAID)

Terminated

Pilot Study of Bydureon to Treat Diabetes in HIV-infected Adults

Diabetes Mellitus | Human Immunodeficiency Virus Infection

United States
Lahore General Hospital

Completed

Exercise Training Versus Ropinirole in Treating Restless Legs Syndrome Among Hemodialysis Patients

Diabetes Complications | Restless Legs Syndrome | Hemodialysis | ESRD (End Stage Renal Disease)

Pakistan
NantBioScience, Inc.

Active, not recruiting

QUILT-2.025 NANT Neoepitope Yeast Vaccine (YE-NEO-001): Adjuvant Immunotherapy Using a Personalized Neoepitope Yeast-Based Vaccine To Induce T-Cell Responses In Subjects W/ Previously Treated Cancers.

Melanoma | Breast Cancer | Colorectal Cancer | Pancreatic Cancer | Non Small Cell Lung Cancer | Head and Neck Squamous Cell Carcinoma | Liver Cancer

United States
Arrowhead Regional Medical Center

Completed

ABO Blood Group Type Association With COVID-19 Severity

COVID-19 | Diabetes Mellitus | COVID-19 Pandemic | Blood Group Antigen Abnormality | Blood Group Incompatibilities

United States
Anahuac University

Completed

Effect of a NSS to Reduce Complications in Patients With Covid-19 and Comorbidities in Stage III

Inflammation | Hypertension | Obesity | Diabetes Mellitus | Mortality | Overweight | COVID19 | Oxygen Saturation

Mexico
The University of Hong Kong

Completed

A Study on the Prevalence of Obstructive Sleep Apnea in Patients With Type II Diabetes Mellitus

Diabetes Mellitus | Obstructive Sleep Apnea

Hong Kong
Cancer Research UK

Active, not recruiting

A CR-UK Phase I Trial of LY3143921

a. Colorectal Cancer | b. High Grade Serous Ovarian Cancer | c. Non Small-cell Lung Cancer (Squamous Cell Variant) | d. Squamous Carcinoma of the Oesophagus | e. Squamous Carcinoma of the Head and Neck (HPV Negative) | f. Urothelial Cancer | g. Breast Cancer (Triple Negative Type) | h. Pancreatic...

United Kingdom
National Cancer Institute (NCI)

Terminated

EF5 and Motexafin Lutetium in Detecting Tumor Cells in Patients With Abdominal or Non-Small Cell Lung Cancer

Fallopian Tube Cancer | Small Intestine Lymphoma | Recurrent Pancreatic Cancer | Stage III Pancreatic Cancer | Stage IV Pancreatic Cancer | Stage IV Ovarian Epithelial Cancer | Stage IV Ovarian Germ Cell Tumor | Primary Peritoneal Cavity Cancer | Stage IIIA Non-small Cell Lung Cancer | Stage IIIB Non-small... and other conditions

United States
Incyte Biosciences International Sàrl

Completed

A Safety and Tolerability Study of INCAGN02385 in Select Advanced Malignancies

Cervical Cancer | Hepatocellular Carcinoma | Esophageal Cancer | Ovarian Cancer | Mesothelioma | Non-small Cell Lung Cancer (NSCLC) | Urothelial Carcinoma | Merkel Cell Carcinoma | Diffuse Large B-cell Lymphoma | Triple-negative Breast Cancer | Renal Cell Carcinoma (RCC) | Small Cell Lung Cancer (SCLC) | Squamous... and other conditions

United States
University of South Florida
Boston University; Duke University; Data Management and Coordinating Center (DMCC)

Completed

Reproductive Health in Men and Women With Vasculitis

Giant Cell Arteritis | Vasculitis, Central Nervous System | Wegener's Granulomatosis | Microscopic Polyangiitis | Churg-Strauss Syndrome | Polyarteritis Nodosa | Takayasu's Arteritis | Kawasaki Disease | Behcet's Disease | Henoch-schoenlein Purpura | Drug-induced Necrotizing Vasculitis

United States
University Hospital, Ioannina
Greece 2021 Committee; Hellenic Stroke Organization; Municipality of North Kynouria and other collaborators

Recruiting

The North Kynouria Project

Myocardial Infarction | Heart Diseases | Cardiovascular Diseases | Coronary Disease | Hypertension | Diabetes Mellitus | Dyslipidemias | Peripheral Artery Disease | Cerebrovascular Disease | Stroke (CVA) or TIA

Greece
Shanghai Zhongshan Hospital
Fudan University; Amoy Diagnostics Co., LTD

Not yet recruiting

Application of ctDNA in Evaluation of Neoadjuvant Chemotherapy Efficacy and Exploration of Chemoresistance Mechanisms in Pancreatic Cancer

Patients With Non-metastatic Pancreatic Cancer | Evaluation of Tumor Resectability Shall be Made in Consensus at Multidisciplinary Meetings, According to NCCN Guideline Version 1.2022 Pancreatic Adenocarcinoma

China
Formation Biologics

Terminated

AVID100 in Advanced Epithelial Carcinomas

Non Small Cell Lung Cancer | Triple Negative Breast Cancer | Head and Neck Squamous Cell Carcinoma | Solid Tumor, Adult

United States
Mayo Clinic
Intuitive Surgical; Siemens Corporation, Corporate Technology

Active, not recruiting

Cios Mobile 3D Spin for Robotic Bronchoscopy

Lung Cancer | Lung Adenocarcinoma | Lung Cancer, Nonsmall Cell | Pulmonary Cancer | Pulmonary Nodule, Solitary

United States
Shanghai Pulmonary Hospital, Shanghai, China

Completed

Comparison of Post-operative Pain and Quality of Life Between Subxiphoid and Intercostal VATS for Lung Cancer

Lung Diseases | Carcinoma, Non-Small-Cell Lung | Lung Neoplasms | Carcinoma, Bronchogenic | Thoracic Surgery | Thoracic Neoplasm

China
Sanofi

Completed

Efficacy of SR121463B in Patients With Syndrome of Inappropriate Antidiuretic Hormone Secretion

Hyponatremia | Syndrome of Inappropriate ADH (SIADH) Secretion

France, Germany, Belgium, Hungary
Herlev Hospital

Completed

Arginase-1 Peptide Vaccine in Patients With Metastatic Solid Tumors

Breast Cancer | Colorectal Cancer | Ovarian Cancer | Non Small Cell Lung Cancer | Metastatic Cancer | Squamous Cell Carcinoma of the Head and Neck | Urothelial Carcinoma | Malignant Melanoma

Denmark
Novo Nordisk A/S

Completed

Safety and Efficacy of Long-term Somatropin Treatment in Children (GrowthWIN II)

Turner Syndrome | Growth Hormone Disorder | Growth Hormone Deficiency in Children | Genetic Disorder | Foetal Growth Problem | Small for Gestational Age | Growth Disorder | Idiopathic Short Stature

Germany
University Health Network, Toronto
Novo Nordisk A/S

Withdrawn

Psoriatic Arthritis Treated With Liraglutide Therapy: a QUality of Life and Efficacy Study (PLAQUE)

Psoriasis | Type 2 Diabetes | Impaired Glucose Tolerance | Psoriatic Arthritis

Canada
Case Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Quality of Life in Younger Leukemia and Lymphoma Survivors

Pain | Lymphoma | Leukemia | Fatigue | Small Intestine Cancer | Cancer Survivor | Anxiety Disorder | Psychosocial Effects of Cancer and Its Treatment | Lymphoproliferative Disorder | Long-term Effects Secondary to Cancer Therapy in Adults

United States
Beatrice Aramini

Completed

The Influence of Cancer Stem-cells on Risk of Relapse in Patients Harboring Adenocarcinoma and Squamous Cell Carcinoma of the Lung

Lung Cancer, Nonsmall Cell | Relapse/Recurrence | CSC

Italy
Robert Lowsky
National Cancer Institute (NCI)

Completed

A Phase I/II Study of Intratumoral Injection of SD-101

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma | Recurrent Marginal Zone Lymphoma | Splenic Marginal Zone Lymphoma | Recurrent Small Lymphocytic...

United States
National Cancer Institute (NCI)

Completed

Rituximab and Interleukin-12 in Treating Patients With B-Cell Non-Hodgkin's Lymphoma

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma | Recurrent Mantle Cell Lymphoma | Splenic Marginal Zone Lymphoma | Recurrent Small Lymphocytic Lymphoma

United States
AstraZeneca

Completed

Percentage of Secondary Prevention Patients Treated to Their LDL-C Targets

Diabetes Mellitus | Peripheral Vascular Diseases | Atherosclerosis | Carotid Stenosis | Hyperlipidemias | Coronary Heart Disease

Austria
University of South Florida
Boston University; Yale University

Completed

Vasculitis Illness Perception (VIP) Study

Giant Cell Arteritis | Microscopic Polyangiitis | Churg-Strauss Syndrome | Polyarteritis Nodosa | Takayasu's Arteritis | Behcet's Disease | CNS Vasculitis | Henoch-Schoenlein Purpura | Wegener Granulomatosis

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Deferoxamine for the Treatment of Hemochromatosis

Diabetes Mellitus | Heart Disease | Thalassemia | Hemochromatosis

United States
Chiltern Pesquisa Clinica Ltda

Completed

Immunogenicity, Safety, and Tolerability of an MF59-Adjuvanted Versus Non-Adjuvanted Influenza Vaccines in Patients With Chronic Pulmonary Disease, Chronic Heart Disease, or Diabetes Mellitus

Diabetes Mellitus | Chronic Pulmonary Disease | Chronic Heart Disease | H1N1 Influenza Virus

Brazil
University of Illinois at Chicago
Centers for Medicare and Medicaid Services

Completed

Coordinated HEalthcare for Complex Kids (CHECK)

Diabetes Mellitus | Premature Birth | Asthma | Sickle Cell Disease
AstraZeneca

Completed

Percentage of Secondary Prevention Patients Treated to Their LDL-C Targets

Diabetes Mellitus | Peripheral Vascular Diseases | Atherosclerosis | Carotid Stenosis | Hyperlipidemias | Coronary Heart Disease

Austria
Novo Nordisk A/S

Completed

Norditropin NordiFlex® Device Compared to the Device Previously Used by Patients or Parents

Chronic Kidney Disease | Turner Syndrome | Chronic Renal Insufficiency | Growth Hormone Disorder | Growth Hormone Deficiency in Children | Genetic Disorder | Delivery Systems | Foetal Growth Problem | Small for Gestational Age

France
Novo Nordisk A/S

Completed

Usability and Tolerability of the Norditropin NordiFlex® Injection Device in Children Never Previously Treated With Growth Hormone

Chronic Kidney Disease | Turner Syndrome | Chronic Renal Insufficiency | Growth Hormone Disorder | Growth Hormone Deficiency in Children | Genetic Disorder | Delivery Systems | Foetal Growth Problem | Small for Gestational Age

France
Prelude Therapeutics

Active, not recruiting

A Study of PRT3645 in Participants With Select Advanced or Metastatic Solid Tumors

Sarcoma | Breast Cancer | Glioblastoma | Malignant Mesothelioma | Endometrial Cancer | Head and Neck Squamous Cell Carcinoma | Non-small Cell Lung Cancers

United States, Singapore
University of KwaZulu
King's College London; University of Oxford; University of East Anglia; University... and other collaborators

Recruiting

ENHANCE-EvideNce Led Co-created HeAlth Systems interventioNs for MLTCs CarE (ENHANCE)

Depression | Myocardial Infarction | HIV Infections | Stroke | Hypertension | Diabetes Mellitus | Asthma

South Africa
Synchron Medical, Inc.

Active, not recruiting

COMMAND Early Feasibility Study: Implantable BCI to Control a Digital Device for People With Paralysis

Paralysis | Amyotrophic Lateral Sclerosis | Muscular Dystrophies | Spinal Cord Injuries | Neurologic Disorder | Spinal Muscular Atrophy | Cervical Spinal Cord Injury | Stroke, Lacunar | Paralysis; Stroke | Stroke Brainstem | Tetraplegic; Paralysis | Quadriplegia/Tetraplegia

United States
Moritz Oberndorfer
Merck Gesellschaft mbH, Austria

Completed

Lipid Profile and Diabetes Mellitus in People With HIV

HIV Infections | Diabetes Mellitus | Dyslipidemias | Cardiovascular Risk Factor

Austria
Pharmassist Ltd
University of Athens

Active, not recruiting

Validation of Molecular Diagnostic Assays to Detect Cancer Biomarkers in Blood and Primary Tumor in HNSCC/NSCLC/Melanoma

Melanoma | Non Small Cell Lung Cancer | Head and Neck Squamous Cell Carcinoma

Greece
Genmab
BioNTech SE

Recruiting

GEN1042 Safety Trial and Anti-tumor Activity in Subjects With Malignant Solid Tumors

Melanoma | Malignant Solid Tumor | Non Small Cell Lung Cancer (NSCLC) | Pancreatic Ductal Adenocarcinoma (PDAC) | Head and Neck Squamous Cell Carcinoma (HNSCC) | Colorectal Cancer (CRC)

United States, Taiwan, Spain, Israel, Korea, Republic of, France, Italy, Denmark, Germany, United Kingdom, Georgia, Moldova, Republic of
University of South Florida
Boston University; University of Pennsylvania; Data Management and Coordinating...

Completed

Educational Needs of Patients With Systemic Vasculitis

Giant Cell Arteritis | Vasculitis, Central Nervous System | Microscopic Polyangiitis | Churg-Strauss Syndrome | Polyarteritis Nodosa | Takayasu's Arteritis | Behcet's Disease | Henoch-Schoenlein Purpura | Wegener Granulomatosis

United States
NICHD Neonatal Research Network
National Institute of Nursing Research (NINR); National Eye Institute (NEI); National... and other collaborators

Completed

Supplemental Therapeutic Oxygen for Prethreshold Retinopathy of Prematurity (STOP-ROP)

Retinopathy of Prematurity | Blindness | Infant, Small for Gestational Age | Infant, Premature | Infant, Low Birth Weight | Infant, Newborn

United States
Indonesia University
Leiden University Medical Center

Active, not recruiting

COVID-19, Aging, and Cardiometabolic Risk Factors Study (CARAMEL)

Obesity | Diabetes Mellitus | Covid19 | Aging | Immune System Disorder | Cardiometabolic Syndrome

Indonesia
NICHD Neonatal Research Network
National Center for Research Resources (NCRR)

Completed

Persistent Pulmonary Hypertension of the Newborn (PPHN) Observational Study (PPHN)

Persistent Fetal Circulation Syndrome | Infant, Small for Gestational Age | Persistent Pulmonary Hypertension of Newborn | Infant, Premature | Infant, Low Birth Weight | Infant, Newborn

United States
Janux Therapeutics

Recruiting

Study of JANX008 in Subjects With Advanced or Metastatic Solid Tumor Malignancies

Renal Cell Carcinoma | Non-Small Cell Lung Cancer | Squamous Cell Carcinoma of the Head and Neck | Colorectal Carcinoma

United States
LG Chem

Recruiting

Long-term Safety and Effectiveness of Growth Hormone With GHD, TS, CRF, SGA , ISS and PWS in Children (LGS)

Growth Hormone Deficiency | Chronic Renal Failure | Turner Syndrome | Small for Gestational Age | Idiopathic Short Stature

Korea, Republic of
Karolinska Institutet

Completed

Beta-cell Function in Glucose Abnormalities and Acute Myocardial Infarction (BEGAMI)

Myocardial Infarction | Diabetes Mellitus | Impaired Glucose Tolerance | Unstable Angina Pectoris

Sweden
University of Lahore

Unknown

Comparison of Mg Vs. K Supplementation on Insomnia in Diabetics

Focus of Study is on Insomnia Among Diabetic Patients

Pakistan
Icahn School of Medicine at Mount Sinai
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

Hormones and Sexual Function Predict Outcomes in Revascularized Men With Diabetes (HEART-MEND)

Coronary Artery Disease | Diabetes Mellitus | Erectile Dysfunction | AD | Androgen Deficiency | ED | Coronary Revascularization

United States
LG Life Sciences

Completed

Evaluation of the Ease of Use, Preference, and Safety of EutropinPen Inj.

Growth Hormone Deficiency | Chronic Renal Failure | Turner Syndrome | Infant, Small for Gestational Age | Short Stature, Idiopathic

Korea, Republic of
Universitaire Ziekenhuizen KU Leuven

Completed

The Prevalence of Foot Complaints/Problems and Ulcers in a Pre-dialysis Population

Diabetes Mellitus | Foot Ulcer | Chronic Kidney Diseases | Pre-dialysis

Belgium
Genmab
BioNTech SE

Active, not recruiting

GEN1046 Safety Trial in Patients With Malignant Solid Tumors

Cervical Cancer | Squamous Cell Carcinoma of the Head and Neck | Triple Negative Breast Cancer | Non-small Cell Lung Cancer | Solid Tumors | Endometrial Carcinoma | Urothelial Carcinoma

United States, Spain, Israel, Czechia, Georgia, Italy, Poland, Turkey, Hungary, Ukraine

Clinical Trials on Small Vessel Disease of Diabetes Mellitus

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