Clinical Trials on Solid Lesions of the GI Tract or of Adjacent Organs in United Kingdom

Total 898 results

Nutricia Research

Unknown

Neocate In Infants and Children With Complex Conditions (NICC)

Complex Conditions, Including Impairment of the GI Tract

United Kingdom, United States, Germany
National Cancer Institute (NCI)

Completed

SGN-00101 Vaccine in Treating Human Papillomavirus in Patients Who Have Abnormal Cervical Cells

Cervical Cancer | High-grade Squamous Intraepithelial Lesion | Atypical Squamous Cells of Undetermined Significance | Low-grade Squamous Intraepithelial Lesion

United States
Medrobotics Corporation

Unknown

Post-Market Clinical Follow-Up to Access & Visualize the Anus, Rectum, & Distal Colon During Transanal Procedures

Disease or Lesions of the Anus, Rectum, or Distal Colon

United States
Guy's and St Thomas' NHS Foundation Trust

Active, not recruiting

MR-simulation in Radiotherapy for Prostate Cancer (FIMRA-P)

Cancer of the PROSTATE

United Kingdom
Incyte Corporation

Active, not recruiting

Study of INCA 0186 in Subjects With Advanced Solid Tumors

Advanced Solid Tumors | Squamous Cell Carcinoma of the Head and Neck (SCCHN) | Gastrointestinal (GI) Malignancies

United States, Netherlands, Spain, United Kingdom, Belgium, Austria
Inovio Pharmaceuticals

Completed

Evaluation of VGX-3100 and Electroporation Alone or in Combination With Imiquimod for the Treatment of HPV-16 and/or HPV-18 Related Vulvar HSIL (Also Referred as: VIN 2 or VIN 3)

Human Papillomavirus (HPV) | Vulvar Dysplasia | Vulvar Intraepithelial Neoplasia (VIN) | Vulvar High Grade Squamous Intraepithelial Lesion (HSIL) | VIN2 | VIN3 | Pre-cancerous Lesions of the Vulva

United States
National Cancer Institute (NCI)

Terminated

Immunotherapy With E6 T Cell Receptor (TCR) T Cells for Vulvar High-Grade Squamous Intraepithelial Lesions

Human Papillomavirus | HPV-16 | High Grade Squamous Intraepithelial Lesion

United States
Inovio Pharmaceuticals

Completed

REVEAL 2 Trial (Evaluation of VGX-3100 and Electroporation for the Treatment of Cervical HSIL)

Cervical Dysplasia | Cervical High Grade Squamous Intraepithelial Lesion | HSIL

United States, Spain, Lithuania, Estonia, South Africa, Argentina, Brazil, Finland, Poland, Puerto Rico
AIDS Malignancy Consortium
National Cancer Institute (NCI); University of Arkansas; The Emmes Company, LLC

Active, not recruiting

Imiquimod, Fluorouracil, or Observation in Treating HIV-Positive Patients With High-Grade Anal Squamous Skin Lesions

HIV Infection | Anal Intraepithelial Neoplasia | High-grade Squamous Intraepithelial Lesion

United States, Puerto Rico
Institute of Cancer Research, United Kingdom
Royal Marsden NHS Foundation Trust

Unknown

A Study of Enzalutamide in Combination With AZD5363 in Patients With mCRPC (RE-AKT)

Adenocarcinoma of the Prostate

United Kingdom
Institute of Cancer Research, United Kingdom
Royal Marsden NHS Foundation Trust

Unknown

TOPARP: A Phase II Trial of Olaparib in Patients With Advanced Castration Resistant Prostate Cancer (TOPARP)

Adenocarcinoma of the Prostate

United Kingdom
Perspective Therapeutics

Recruiting

Targeted Alpha-Particle Therapy for Advanced SSTR2 Positive Neuroendocrine Tumors (212-Pb-VMT)

Neuroendocrine Tumors | Pheochromocytoma | Carcinoid Tumor | Paraganglioma | Neuroendocrine Tumor of the Lung | Neuroendocrine Carcinoma Metastatic | Neuroendocrine Tumor of Pancreas | Neuroendocrine Tumor Carcinoid | Carcinoid Tumor of GI System

United States
Baxalta now part of Shire

Completed

Phase 1 Study of Anti-Macrophage Migration Inhibitory Factor (Anti-MIF) Antibody in Solid Tumors

Malignant Solid Tumors | Metastatic Adenocarcinoma of the Colon or Rectum

Germany, United States
Duke University
Wallace H. Coulter Foundation

Completed

Real Time In-Vivo Dosimetry For Gynecologic Brachytherapy

Cancer of the Cervix, Cancer of the Endometrium

United States
Millennium Pharmaceuticals, Inc.

Completed

A Phase 1 Study of Alisertib Participants With Advanced Solid Tumors Including Castration-Resistant Prostate Cancer Receiving a Standard Docetaxel Regimen

Advanced Solid Tumors | Adenocarcinoma of the Prostate

United States
University Hospitals of North Midlands NHS Trust

Completed

Comparison Of DIR-MRI And DCE-MRI In Detection Of Prostate Cancer: A Pilot Study (DIRMP)

Cancer of the Prostate

United Kingdom
Baylor College of Medicine
Medical University of South Carolina; M.D. Anderson Cancer Center; The University... and other collaborators

Completed

The Effectiveness of High Resolution Microendoscopy for People Living With HIV

Anal High Grade Squamous Intraepithelial Lesion

United States
Inovio Pharmaceuticals

Completed

REVEAL 1 (Evaluation of VGX-3100 and Electroporation for the Treatment of Cervical HSIL) (REVEAL 1)

Cervical Dysplasia | Cervical High Grade Squamous Intraepithelial Lesion | HSIL

United States, Spain, Portugal, Italy, Philippines, Thailand, Slovakia, Lithuania, Estonia, Belgium, South Africa, Germany, Argentina, United Kingdom, Poland, Puerto Rico, Finland, Mexico, Peru
Case Comprehensive Cancer Center

Terminated

Treatment Decision Analysis Model for Prostate Cancer: A Randomized Trial

Adenocarcinoma of Prostate | Adenocarcinoma of the Prostate Stage I | Adenocarcinoma of the Prostate Stage II | Adenocarcinoma of the Prostate Stage III

United States
Memorial Sloan Kettering Cancer Center
AstraZeneca

Completed

Evaluating Immune Therapy, Durvalumab (MEDI4736) With Tremelimumab for Metastatic, Non-transitional Cell Carcinoma of the Urinary Tract

Adenocarcinoma of the Bladder | Squamous Cell Carcinoma of the Bladder | Metastatic Bladder Cancer | Non-Transitional Cell Carcinoma of the Urothelial Tract | Small Cell of the Bladder

United States
Tarveda Therapeutics

Recruiting

PEN-866 in Patients With Advanced Solid Malignancies

Neoplasms | Carcinoma | Small Cell Lung Carcinoma | Gastric Cancer | Pancreatic Adenocarcinoma | Solid Tumor | Gastric Adenocarcinoma | Small-cell Lung Cancer | Advanced Cancer | Pancreatic Ductal Adenocarcinoma | Adenocarcinoma of the Pancreas | Endometrial Adenocarcinoma | Squamous Cell Carcinoma of the Penis | Gastroesophageal... and other conditions

United States
Royal Surrey County Hospital NHS Foundation Trust

Completed

Hemi-Ablative Prostate Brachytherapy (HAPpy)

Prostatic Neoplasms | Cancer of the Prostate

United Kingdom
Stony Brook University

Unknown

Non-Invasive Hemoglobin Monitoring of Women Undergoing Cesarean Delivery

Complications of Pregnancy, Childbirth and the Puerperium

United States
Institute of Cancer Research, United Kingdom
St George's Healthcare NHS Trust

Completed

A Phase II Trial of Vinflunine Chemotherapy in Locally-advanced and Metastatic Carcinoma of the Penis (VinCaP) (VinCaP)

Locally-advanced or Metastatic Penile Neoplasms

United Kingdom
Milton S. Hershey Medical Center

Completed

Endometriosis and the Appendix - Incidence and Pathologic Analysis

Endometriosis of the Appendix

United States
Queen Mary University of London

Unknown

Characterising Metastatic Penile Cancer Using Molecular Imaging - Hybrid MRI-PET [MRI-PET] (MRI-PET)

Squamous Cell Carcinoma of the Penis

United Kingdom
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

A Non-Interventional Follow Up Study For Subjects Who Received Sildenafil for Persistent Pulmonary Hypertension of the Newborn (PPHN)

Pulmonary Hypertension, Persistent, of the Newborn

United Kingdom
OSI Pharmaceuticals

Completed

A Study of OSI-7904L Versus 5-FU/LV as Treatment in Patients With Biliary Tract Cancer

Locally Advanced or Metastatic Adenoca of the Biliary Tract

United States, Belgium, Germany, Poland, Romania, Switzerland
Memorial Sloan Kettering Cancer Center

Terminated

Improving End of Life Care in Head and Neck Cancer

The Families or Next of Kin of Patients Treated at MSKCC for Non-cutaneous Squamous Cell Carcinomas of the | Upper Aerodigestive Tract

United States
Institute of Cancer Research, United Kingdom
Sanofi; Janssen, LP; Menarini Group; University of Twente; Prostate Cancer UK

Terminated

Utilising CTC Counts to Optimize Systemic Therapy of Metastatic Prostate Cancer (CTC-STOP)

Adenocarcinoma of the Prostate

United Kingdom
Tigris Pharmaceuticals

Completed

A Two-Stage Phase 2 Study Of A-007 Topical Gel in High-Grade Squamous Intraepithelial Lesions (HSIL) (TG-003)

Cervical Intraepithelial Neoplasia | Uterine Cervical Dysplasia

United States
Dana-Farber Cancer Institute

Completed

Incorporating MR Imaging Into Prostate Radiotherapy Treatment Planning

Prostate Cancer | Adenocarcinoma of the Prostate Stage I | Adenocarcinoma of the Prostate Stage II | Adenocarcinoma of the Prostate Stage III

United States
University of Michigan Rogel Cancer Center

Completed

Vessel Sparing Prostate Radiation Therapy

Cancer of the PROSTATE

United States
Astellas Pharma Inc
Astellas Pharma US, Inc.

Completed

A Study for the Treatment of Hormone Refractory Prostate Cancer (HRPC) in Patients Previously Treated With Chemotherapy

Prostate Cancer | Cancer of the Prostate | Prostatic Cancer | Cancer of Prostate

Netherlands, United States, United Kingdom
Anova Enterprises, Inc

Recruiting

AnovaOS Network Powered Patient Registry

Neoplasms | Infectious Disease | External Causes of Morbidity and Mortality | Pregnancy, Childbirth and the Puerperium | Diseases of the Blood and Blood-Forming Organs and Certain Disorders Involving the Immune Mechanism (D50-D89) | Endocrine, Nutritional and Metabolic Diseases (E00-E89) | Mental... and other conditions

United States
Dendreon

Completed

Sipuleucel-T Manufacturing Demonstration Study

Prostate Cancer | Prostate Neoplasms | Cancer of the Prostate | Neoplasms, Prostate | Prostatic Cancer | Neoplasms, Prostatic | Cancer of Prostate

Austria, France, Netherlands, United Kingdom
Noah Hahn, M.D.
Pfizer; Hoosier Cancer Research Network

Terminated

Neoadjuvant Cisplatin, Gemcitabine, Sunitinib Malate + Radical Cystectomy for TCC

Transitional Cell Carcinoma of the Bladder

United States, United Kingdom
Tigris Pharmaceuticals

Completed

Safety and Efficacy of A-007 Topical Gel in the Treatment of High-Grade Squamous Intraepithelial Lesions (HSIL) of the Cervix

Cervical Intraepithelial Neoplasia | Uterine Cervical Dysplasia

United States
University Hospitals Bristol and Weston NHS Foundation...
Sanofi

Completed

A Trial of Cabazitaxel Chemotherapy in Relapsed Locally Advanced &/or Metastatic Carcinoma of the Penis (JAVA-P)

Penile Neoplasm

United Kingdom
THEVAX Genetics Vaccine
Clinical Research Management, Inc.

Unknown

Safety and Efficacy Study of TVGV-1 Vaccine to Treat HPV Induced Cervical HSIL

Human Papillomavirus | High-Grade Squamous Intraepithelial Lesions

United States
National Center for Plastic Surgery, Virginia
Walter Reed Army Medical Center; Ohio State University Comprehensive Cancer... and other collaborators

Completed

Evaluating AlloMax in Immediate Expander-Based Breast Reconstruction Study

Malignant Neoplasm of the Breast | Acquired Absence of the Breast

United States
National Cancer Institute (NCI)

Completed

Erlotinib in Treating Patients With Advanced Non-Small Cell Lung Cancer, Ovarian Cancer, or Squamous Cell Carcinoma of the Head and Neck

Stage IV Ovarian Epithelial Cancer | Stage IIIA Non-small Cell Lung Cancer | Stage IIIB Non-small Cell Lung Cancer | Recurrent Ovarian Epithelial Cancer | Recurrent Squamous Cell Carcinoma of the Hypopharynx | Recurrent Squamous Cell Carcinoma of the Larynx | Recurrent Squamous Cell Carcinoma... and other conditions

United States
Leonard Appleman
Sanofi-Synthelabo

Completed

Study of Docetaxel and Oxaliplatin in Metastatic Transitional Cell Cancer (TCC) of the Urothelial Tract

Metastatic Transitional Cell Cancer of the Urothelial Tract

United States
Abramson Cancer Center of the University of Pennsylvania

Completed

Adjuvant Proton Therapy or IMRT for the Treatment of Bladder Cancer

Urothelial Carcinoma of the Bladder

United States
Memorial Sloan Kettering Cancer Center
Northwestern University; The City College of New York

Completed

Validation of a Health-Related Symptom Index for Persons Diagnosed With and Either Treated or Monitored for Anal High-Grade Squamous Intraepithelial Lesions (HSIL)

Anal High-Grade Squamous Intraepithelial Lesions

United States
University College, London
UCLH

Unknown

D-mannose for the Prevention of UTIs in Multiple Sclerosis

Multiple Sclerosis | Recurrent Urinary Tract Infections

United Kingdom
National Cancer Institute (NCI)

Terminated

Vorinostat in Treating Patients With Locally Recurrent or Metastatic Cancer of the Urothelium

Metastatic Transitional Cell Cancer of the Renal Pelvis and Ureter | Recurrent Transitional Cell Cancer of the Renal Pelvis and Ureter | Regional Transitional Cell Cancer of the Renal Pelvis and Ureter | Transitional Cell Carcinoma of the Bladder | Localized Transitional Cell Cancer of the...

United States
AIDS Malignancy Consortium
National Cancer Institute (NCI); The Emmes Company, LLC

Completed

Cidofovir in Treating HIV-Infected Patients With High-Grade Squamous Intraepithelial Lesions of the Skin Near the Anus

Precancerous Condition | Anal Cancer

United States
National Cancer Institute (NCI)

Completed

Alvespimycin Hydrochloride in Treating Patients With Metastatic or Unresectable Solid Tumors

Recurrent Prostate Cancer | Unspecified Adult Solid Tumor, Protocol Specific | Stage III Renal Cell Cancer | Recurrent Melanoma | Male Breast Cancer | Stage IV Breast Cancer | Stage IV Melanoma | Stage IV Ovarian Epithelial Cancer | Stage IIIB Breast Cancer | Stage IV Renal Cell Cancer | Recurrent Renal Cell... and other conditions

United States
Janssen Research & Development, LLC

Active, not recruiting

A Study to Evaluate the Safety, Efficacy, Pharmacokinetics and Pharmacodynamics of M281 Administered to Pregnant Women at High Risk for Early Onset Severe Hemolytic Disease of the Fetus and Newborn (HDFN)

Hemolytic Disease of the Fetus and Newborn

United States, Canada, Netherlands, Belgium, Germany, Spain, Sweden, United Kingdom, Australia

Clinical Trials on Solid Lesions of the GI Tract or of Adjacent Organs in United Kingdom

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Montenegro

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations