Clinical Trials on Spinal Muscular Atrophies of Childhood

Total 4166 results

BG Unfallklinik

Completed

The Unstable Thoracic Cage Injury

Thoracic Spine Fracture | Concomitant Sternal Fracture
Sue O'Dorisio
National Cancer Institute (NCI); Ride for Kids

Withdrawn

Efficacy of 68Ga-DOTATOC Positron Emission Tomography (PET) CT in Children and Young Adults With Brain Tumors

Recurrent Childhood Medulloblastoma | Recurrent Childhood Ependymoma | Untreated Childhood Brain Stem Glioma | Untreated Childhood Medulloblastoma | Untreated Childhood Supratentorial Primitive Neuroectodermal Tumor | Adult Anaplastic Astrocytoma | Adult Anaplastic Ependymoma | Adult Anaplastic Oligodendroglioma and other conditions

United States
Assiut University

Recruiting

Could Ephedrine Replace Dexmedetomidine Fordexmedetomidine Prevention of Shivering in Women Undergoing Cesarean Section Under Spinal Anaesthesia

Prevention of Shivering With Spinal Anaesthesia

Egypt
Marco Capogrosso
Roche-Genentech

Recruiting

Spinal Cord Stimulation in Spinal Muscular Atrophy (SCSinSMA)

Spinal Muscular Atrophy Type 3 | Spinal Muscular Atrophy Type 4

United States
Institut de Myologie, France
Institut Roche

Completed

Prospective Study of the Natural History of Patients With Type 2 and 3 Spinal Muscular Atrophy (NatHis-SMA)

Type 2 Spinal Muscular Atrophy | Type 3 Spinal Muscular Atrophy

Belgium, France, Germany
Cairo University

Not yet recruiting

Oral Health-Related Quality of Life of Early Childhood Caries Using Silver Diamine Fluoride Versus Drill and Fill Technique

Early Childhood Caries | Oral Health Related Quality of Life
Mental Health Services in the Capital Region, Denmark
Frederiksberg University Hospital; The Danish Mental Health Foundation; Defactum...

Completed

3-year Follow-up of the Mind My Mind RCT (MindMyMindFU)

Depressive Symptoms | Mental Health Disorder | Emotional Problem | Anxiety Disorder of Childhood | Behavior Problem of Childhood and Adolescence

Denmark
University of Texas at Austin

Not yet recruiting

Clinical Validation of zEEG, a Wireless EEG Recording System for Pediatric and Adult Patients With Epilepsy

Epilepsy | EEG With Abnormally Slow Frequencies | EEG; Paroxysms, Occipital, Epilepsy of Childhood | EEG With Periodic Abnormalities | EEG; Spikes, Centrotemporal, Epilepsy of Childhood

United States
Vanderbilt University Medical Center

Completed

Intraoperative Infusion of Precedex to Reduce Length of Stay After Lumbar Spine Fusion (DEXREDLOS)

Spinal Diseases | Spinal Stenosis | Spinal Fusion Acquired | Lesions of Lumbosacral Intervertebral Disc

United States
National Cancer Institute (NCI)

Completed

Cilengitide in Treating Children With Refractory Primary Brain Tumors

Recurrent Childhood Medulloblastoma | Recurrent Childhood Ependymoma | Childhood Choroid Plexus Tumor | Childhood Craniopharyngioma | Childhood Ependymoblastoma | Childhood Grade I Meningioma | Childhood Grade II Meningioma | Childhood Grade III Meningioma | Childhood High-grade Cerebellar Astrocytoma | Childhood High-grade Cerebral Astrocytoma and other conditions

United States
University of Minho
Universidade do Porto

Completed

The Impact of an Intervention Taught by Trained Teachers on Childhood BMI z Score

Evidence of an Intervention on Childhood BMI z Score

Portugal
United States Army Research Institute of Environmental...

Recruiting

Molecular Mechanisms Underlying Anabolic Resistance to Protein Intake During Muscle Disuse

Muscular Disorders, Atrophic | Muscle Atrophy | Disuse Atrophy | Atrophy, Disuse | Disuse Atrophy Muscle of Thigh

United States
Boston University Charles River Campus

Not yet recruiting

Brief, Remote Treatment of Youth Injection Phobia and Measurement of Novel, Disorder-congruent Cognitive Bias Tasks

Anxiety Disorder of Childhood
Materia Medica Holding

Completed

Efficacy and Safety of Tenoten in the Treatment of Children With Anxiety Disorders

Anxiety Disorder of Childhood

Russian Federation
National Neuroscience Institute
Nanyang Technological University; Institute for Infocomm Research; Institute... and other collaborators

Active, not recruiting

[BrainConnexion] - Neurodevice Phase I Trial

Motor Neuron Disease | Amyotrophic Lateral Sclerosis | Muscular Dystrophies | Spinal Cord Injuries | Tetraplegia | Tetraplegia/Tetraparesis | Locked-in Syndrome

Singapore
CHU de Reims

Completed

Quality of Life in Neuromuscular Disease (QoLNMD)

Quality of Life | Muscular Dystrophies

France
National Cancer Institute (NCI)

Completed

Lenalidomide in Treating Young Patients With Recurrent, Progressive, or Refractory CNS Tumors

Recurrent Childhood Medulloblastoma | Recurrent Childhood Ependymoma | Childhood Atypical Teratoid/Rhabdoid Tumor | Childhood Choroid Plexus Tumor | Childhood Craniopharyngioma | Childhood Ependymoblastoma | Childhood Grade I Meningioma | Childhood Grade II Meningioma | Childhood Grade III Meningioma | Childhood High-grade Cerebellar Astrocytoma and other conditions

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Collecting and Storing Blood and Brain Tumor Tissue Samples From Children With Brain Tumors

Recurrent Childhood Medulloblastoma | Recurrent Childhood Ependymoma | Childhood Atypical Teratoid/Rhabdoid Tumor | Ependymoma | Childhood Craniopharyngioma | Childhood Grade I Meningioma | Childhood Grade II Meningioma | Childhood Grade III Meningioma | Childhood Infratentorial Ependymoma | Childhood... and other conditions

United States, Canada, Australia, New Zealand, Puerto Rico, Switzerland
Nemours Children's Clinic

Recruiting

Genetics of Pediatric-Onset Motor Neuron and Neuromuscular Diseases

Charcot-Marie-Tooth Disease | Motor Neuron Disease | Amyotrophic Lateral Sclerosis | Muscular Dystrophy | Spinal Muscular Atrophy | Neuromuscular Disease | Spinal Muscular Atrophy With Respiratory Distress 1 | Peroneal Muscular Atrophy

United States
Yonsei University

Completed

The Comparison of Postoperative Pain After Lumbar Fusion Surgery in Intravenous Patient-controlled Analgesia Between Conventional Mode and Optimizing B.I Mode With 'PAINSTOP' Equipment

Back Pain | Spinal Stenosis | Fusion of Spine, Lumbar Region

Korea, Republic of
MTI University

Recruiting

Effect of Posterior Pelvic Tilt on Balance and Sensory Integration in Patients With Non-specific Low Back Pain

Orthopedic Disorder of Spine | Biochemical Lesions Lumbar Region | Back Disorder

Egypt
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI)

Terminated

Palbociclib Isethionate in Treating Younger Patients With Recurrent, Progressive, or Refractory Central Nervous System Tumors

Recurrent Childhood Medulloblastoma | Childhood Choroid Plexus Tumor | Childhood Ependymoblastoma | Childhood Grade III Meningioma | Childhood High-grade Cerebellar Astrocytoma | Childhood High-grade Cerebral Astrocytoma | Childhood Medulloepithelioma | Recurrent Childhood Anaplastic Astrocytoma | Recurrent... and other conditions

United States
Mongi Slim Hospital

Unknown

Leg Elevation for Prevention of Post Spinal Hypotension in Cesarean Section

Effects of; Anesthesia, Spinal and Epidural, in Pregnancy

Tunisia
National Cancer Institute (NCI)

Completed

Temozolomide and O6-Benzylguanine in Treating Children With Recurrent Brain Tumors

Recurrent Childhood Medulloblastoma | Recurrent Childhood Ependymoma | Childhood Choroid Plexus Tumor | Childhood Craniopharyngioma | Childhood Ependymoblastoma | Childhood Grade I Meningioma | Childhood Grade II Meningioma | Childhood Grade III Meningioma | Childhood High-grade Cerebellar Astrocytoma | Childhood High-grade Cerebral Astrocytoma and other conditions

United States
UConn Health

Recruiting

Efficacy Trial of the CALM Intervention

Anxiety Disorder of Childhood

United States
University Hospital, Ghent

Completed

Influence of Continuous Administration of Phenylephrine Versus Dobutamine on Spinal Oxygen Saturation, Measured With Near-infrared Spectroscopy (NIRS). (NIRS continu)

Nfuence of Vasoactive Medication on Spinal Oxygenation

Belgium
University Hospital, Ghent

Completed

Influence of a Bolus Administration of Ephedrine and Phenylephrine on the Spinal Oxygen Saturation, Measured With NIRS. (NIRS BOLUS)

Influence of Vasoactive Medication on Spinal Oxygenation

Belgium
Neo Medical SA
ConfinisCPM

Active, not recruiting

PMCF Neo Pedicle Screw and Cage Systems

Trauma | Degenerative Disc Disease | Spinal Stenosis | Spondylolisthesis | Spinal Tumor | Pseudoarthrosis of Spine

Germany, Spain
McMaster University

Completed

The Regulation of Human Skeletal Muscle Mass by Contractile Perturbation (HYPAT)

Muscle Atrophy | Disuse Atrophy (Muscle) of Lower Leg

Canada
VA Office of Research and Development

Not yet recruiting

iBCI Optimization for Veterans With Paralysis

Amyotrophic Lateral Sclerosis | Muscular Dystrophy | Spinal Cord Injury | Brain Stem Infarctions | Locked-in Syndrome

United States
Weill Medical College of Cornell University

Completed

A Pilot Study of Fear Extinction Learning in Anxious Youth

Anxiety Disorder of Childhood
German Research Foundation

Completed

Effectiveness of the Teacher Module of the Prevention Program for Externalizing Problem Behaviour in Preschoolers (PEP-TE)

Behavior Problem of Childhood and Adolescence

Germany
Hospital Rudolfstiftung
Oesterreichische Muskelforschung

Completed

Myocardial Involvement in Carriers of Duchenne Muscular Dystrophy: An MRI-study

Carrier of Duchenne Muscular Dystrophy

Austria
Cooperative International Neuromuscular Research...
aTyr Pharma, Inc.; Muscular Dystrophy Canada; FSHD Global Research Foundation; FSH...

Completed

A Multicenter Collaborative Study on the Clinical Features, Expression Profiling, and Quality of Life of Infantile Onset FSHD (FSHD)

Facioscapulohumeral Muscular Dystrophy

United States, Canada, Australia, Sweden, United Kingdom
Bispebjerg Hospital

Recruiting

The Impact of Bed Rest, Aging and NMES on Skeletal Muscle

Muscle Function | Neuromuscular Electrical Stimulation | Disuse Atrophy (Muscle) of Lower Extremities | Myofibrillar Protein Synthesis

Denmark
Hospital for Special Surgery, New York

Completed

Does Chewing Gum Hasten Return of Bowel Function Post-Operatively in Patients Undergoing Spinal Surgery

Return of Bowel Function Following Spinal Surgery

United States
Beijing University of Chinese Medicine
Harvard Medical School (HMS and HSDM); China Academy of Chinese Medical Sciences and other collaborators

Recruiting

Risk Assessment and Syndrome Evolution Models for Chronic Atrophic Gastritis Malignant Transformation

Risk Assessment of Chronic Atrophic Gastritis Malignant Transformation

China
Rajesh Deshar

Completed

Effect of Glycopyrrolate on Vasopressors Requirement for Non-elective Caesarean Section Under Spinal Anaesthesia

Hemodynamic Instability | Effect of Drug | Post-spinal Hypotension | Glycopyrrolate

Nepal
Hoffmann-La Roche

Recruiting

A Study to Investigate the Safety and Efficacy of RO7204239 in Combination With Risdiplam (RO7034067) in Participants With Spinal Muscular Atrophy (MANATEE)

Spinal Muscular Atrophy (SMA)

Belgium, United States, Croatia, Japan, Netherlands, Spain, Canada, Poland, United Kingdom, Portugal, Italy, Australia
Northwell Health

Completed

Effect of Nusinersen on Adults With Spinal Muscular Atrophy

Adult Spinal Muscular Atrophy

United States
Hugh McMillan
Families of Spinal Muscular Atrophy; Gwendolyn Strong Foundation

Terminated

Effect of Low-Dose Celecoxib on SMN2 in Patients With Spinal Muscular Atrophy (SMA)

Spinal Muscular Atrophy (SMA)

Canada
AveXis, Inc.
United BioSource, LLC

Recruiting

Registry of Patients With a Diagnosis of Spinal Muscular Atrophy (SMA)

Spinal Muscular Atrophy (SMA)

Japan, United States, Korea, Republic of, Israel, Greece, Ireland, Portugal, Russian Federation, Taiwan
Erasmus Medical Center

Terminated

Web-based Attention Bias Modification Treatment for Childhood Anxiety Disorders (ATTENTIO)

Generalized Anxiety Disorder | Social Anxiety Disorder | Specific Phobia | Anxiety Disorder | Anxiety Disorder of Childhood | Separation Anxiety Disorder of Childhood, Early Onset

Netherlands
Fondazione Policlinico Universitario Agostino Gemelli...

Completed

Ultrasound-assisted or Landmark-based Intrathecal Administration of Nusinersen in Adult Patients With Spinal Muscular Atrophy (The EchoSpin Study) (EchoSpin)

Ultrasonography | Spinal Muscular Atrophy | Anesthesia, Spinal | Spinal Puncture Complications

Italy
Adiyaman University

Completed

The Relationship Between Perfusion Index and Pleth Variability Index and Hemodynamics in Spinal Anesthesia

Effects of Anesthesia Spinal and Epidural in Pregnancy

Turkey
Cairo University

Unknown

Impact of Different Shoe Heel Heights on Spinal Configuration

Impact of Different Heel Heights on Spinal Configuration
Lawson Health Research Institute

Completed

Effect of EPD on the Lumbar Acoustic Window at Term Pregnancy

Effects of; Anesthesia, Spinal and Epidural, in Pregnancy
Instituto de Investigación Hospital Universitario...

Completed

Air Versus Saline Solution for the Localization of the Epidural Space in Labour Analgesia

Effects of Anesthesia Spinal and Epidural in Pregnancy
University Hospital, Montpellier

Completed

Predictive Factors for the Outcome of Young Children Emotional and/or Behavioral Disorders After Psychotherapeutic Intervention

Behavioral Disorders | Emotional Disorder of Childhood

France
NYU Langone Health
National Institute of Mental Health (NIMH); U.S. Department of Education

Completed

ParentCorps: Promoting Healthy Development in Children From Low Income Communities (ParentCorps)

Behavior Problems of Childhood and Adolescence

United States

Clinical Trials on Spinal Muscular Atrophies of Childhood

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Congo, DR of

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

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