Clinical Trials on Spinal+Muscular+Atrophy

Total 58812 results

Gilead Sciences

Completed

Study to Evaluate Safety, Tolerability, and Pharmacokinetics of Idelalisib in Japanese Participants With Relapsed or Refractory Indolent B-Cell Non-Hodgkin Lymphomas (iNHL) or Chronic Lymphocytic Leukemia (CLL)

Follicular Lymphoma | Marginal Zone Lymphoma | Chronic Lymphocytic Leukemia | Small Lymphocytic Lymphoma | Indolent Non-Hodgkin Lymphoma | Lymphoplasmacytic Lymphoma (With or Without Waldenstrom Macroglobulinemia)

Japan
Masonic Cancer Center, University of Minnesota

Terminated

Stem Cell Transplant for Hematological Malignancy

Multiple Myeloma | AML | MDS | Non-hodgkin's Lymphoma | Leukemia, Lymphocytic, Acute | Hodgkin's Disease | Leukemia, Myeloid, Chronic | Leukemia, Lymphocytic, Chronic | JMML

United States
University Hospital, Angers

Unknown

Pharmacogenetic Study of Antimitotic Therapies Involved in Hepatic VOD in Children With Nephroblastoma or ALL (MVO)

Acute Lymphoblastic Leukemia | Nephroblastoma | Hepatic Veno-Occlusive Disease

France
Chang Gung Memorial Hospital

Completed

18F-PM-PBB3 PET Study in Tauopathy Including Alzheimer's Disease, Other Dementias and Normal Controls

Frontotemporal Dementia | Progressive Supranuclear Palsy | Alzheimer's Disease | Vascular Cognitive Impairment | Cortical Basal Syndrome

Taiwan
Virginia Commonwealth University
Genzyme, a Sanofi Company

Completed

Reduced Intensity Total Body Irradiation + Thymoglobulin Followed by Allogeneic PBSCT

Acute Myeloid Leukemia | Leukemia | Multiple Myeloma | Hodgkin Lymphoma | Non-Hodgkin's Lymphoma | Chronic Lymphocytic Leukemia | Myelodysplastic Syndrome | Chronic Myelogenous Leukemia

United States
U.S. Wound Registry

Unknown

Negative Pressure Wound Therapy Registry (NPWTR)

Burns | Diabetic Foot Ulcers | Pressure Ulcer | Surgical Wound Dehiscence | Venous Stasis Ulcer | Other Types of Chronic Non Healing Wounds

United States
Johann Wolfgang Goethe University Hospital
CSL Behring

Completed

Susceptibility to Infections in Ataxia Telangiectasia

Infections | Lung Disease | Immunodeficiency | Ataxia Telangiectasia
OHSU Knight Cancer Institute
National Cancer Institute (NCI)

Completed

Busulfan, Fludarabine, and Total-Body Irradiation in Treating Patients Who Are Undergoing a Donor Stem Cell Transplant for Hematologic Cancer (Bu Flu TBI)

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Multiple Myeloma and Plasma Cell Neoplasm | Precancerous Condition | Myelodysplastic/Myeloproliferative Neoplasms

United States
National Cancer Institute (NCI)

Completed

Erlotinib in Treating Patients With Recurrent Malignant Glioma or Recurrent or Progressive Meningioma

Adult Anaplastic Astrocytoma | Adult Anaplastic Oligodendroglioma | Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma | Recurrent Adult Brain Tumor | Adult Grade I Meningioma | Adult Grade II Meningioma | Adult Grade III Meningioma

United States
Assistance Publique - Hôpitaux de Paris
Pr Joel COSTE, Hôpital Hôtel Dieu - Unité de Bio Statistiques et Epidémiologiques...

Completed

Development of a New Tool for Dyspnea Measurement in Chronic Respiratory Diseases (DYSLIM)

COPD (With - Without Rehabilitation) | Diffuse Interstitial Lung Diseases | Pulmonary Arterial Hypertension Primary or Secondary (Post Embolic .....) | Cystic Fibrosis of the Adult

France
Hospices Civils de Lyon

Unknown

Study of the Prevalence of Fabry Disease in French Dialysis Patients (FABRYDIAL)

End Stage Renal Disease | Fabry Disease | Renal Dialysis

France
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Honolulu Heart Program

Myocardial Infarction | Heart Diseases | Cardiovascular Diseases | Heart Failure | Coronary Disease | Hypertension | Lung Diseases, Obstructive | Chronic Obstructive Pulmonary Disease | Asthma | Dementia | Emphysema | Bronchitis | Cerebrovascular Accident | Aortic Aneurysm, Abdominal | Heart Failure, Congestive
Baylor Research Institute

Completed

Androgenetic Alopecia in Fabry Disease

Fabry Disease

United States
Virginia Commonwealth University
National Cancer Institute (NCI)

Completed

High-Dose Cytarabine Plus Deoxycytidine in Treating With Acute Myelogenous Leukemia or Other Hematologic Malignancies

Lymphoma | Leukemia | Multiple Myeloma and Plasma Cell Neoplasm | Drug/Agent Toxicity by Tissue/Organ

United States
Centre Hospitalier Universitaire, Amiens

Completed

Assessment of Social-emotional Functioning in Neurological Diseases (Emotion)

Stroke | Parkinson's Disease | Alzheimer Disease | Huntington Disease | Lewy Body Dementia

France
City of Hope Medical Center
National Cancer Institute (NCI)

Terminated

Total Marrow and Total Lymph Node Irradiation, Fludarabine, and Melphalan Followed By Donor Stem Cell Transplant in Treating Patients With Advanced Hematological Cancer That Has Not Responded to Treatment

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Multiple Myeloma and Plasma Cell Neoplasm | Myelodysplastic/Myeloproliferative Neoplasms

United States
Seattle Children's Hospital
Actelion

Withdrawn

Inhaled Iloprost as an Adjunct to Inhaled Nitric Oxide in Pediatric Critical Care Patients

Pulmonary Hypertension | Acute Respiratory Distress Syndrome | Congenital Heart Defects | Neonatal Hypoxic Respiratory Failure | Persistent Pulmonary Hypertension of Newborn
Summa Health System

Completed

After Discharge Management of Low Income Frail Elderly

Hypertension | Diabetes Mellitus | Pulmonary Disease, Chronic Obstructive | Osteoarthritis | Atrial Fibrillation | Osteoporosis | Coronary Arteriosclerosis | Cerebrovascular Accident | Heart Failure, Congestive
Thomas Jefferson University
Abbott

Terminated

Effect of Vitamin D Supplement on Inflammation Markers in High-Risk Cardiovascular Patients With Chronic Kidney Disease (VINCA-CKD)

Coronary Artery Disease | Chronic Kidney Disease | Secondary Hyperparathyroidism | Hypovitaminosis D

United States
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI)

Completed

Melphalan, Fludarabine, and Alemtuzumab Followed by Peripheral Stem Cell Transplant in Treating Patients With Hematologic Cancer

Lymphoma | Myelodysplastic Syndromes | Leukemia | Multiple Myeloma and Plasma Cell Neoplasm | Myelodysplastic/Myeloproliferative Neoplasms

United States
University Hospital, Angers

Unknown

Arterial Wall Calcium Load in Pseudoxanthoma Elasticum (Ca-Art-PXE2)

Type 2 Diabetes | Chronic Kidney Disease | Pseudoxanthoma Elasticum

France
University of California, San Francisco
National Cancer Institute (NCI)

Withdrawn

Busulfan and Fludarabine Before Donor Stem Cell Transplant in Treating Patients With Hematologic Cancer

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Anemia | Multiple Myeloma and Plasma Cell Neoplasm | Myelodysplastic/Myeloproliferative Diseases

United States
Centre Hospitalier Universitaire de Nice

Unknown

Detection of Fabry Disease in Chronic Renal Failure Patients in Area Provence - Alpes - Côte d'Azur

Fabry Disease

France
Oswaldo Cruz Foundation
Ministry of Health, Brazil

Terminated

Probiotics for the Prevention of Premature Birth and Neonatal Related Morbidity

Sepsis | Premature Birth | Bronchopulmonary Dysplasia | Bacterial Vaginosis | Periventricular Leukomalacia

Brazil
Hoag Memorial Hospital Presbyterian
Cancer Biotherapy Research Group

Completed

Interleukin-2 Plus Interferon Alfa in Treating Adults With Metastatic Cancer

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Unspecified Adult Solid Tumor, Protocol Specific | Multiple Myeloma and Plasma Cell Neoplasm | Precancerous/Nonmalignant Condition

United States
Case Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

High-Dose Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Hematologic Cancer

Lymphoma | Myelodysplastic Syndromes | Leukemia | Multiple Myeloma and Plasma Cell Neoplasm | Myelodysplastic/Myeloproliferative Diseases

United States
Parker, William H., M.D.
Ethicon, Inc.

Completed

Examining the Long-Term Risks of Oophorectomy

Stroke | Cancer | Breast Cancer | Death | Ovarian Cancer | Coronary Heart Disease | Hip Fracture

United States
Ospedale San Raffaele

Recruiting

Genetics in the Progression of Nephropathies

Hypertension | AKI | CKD | Hematologic Malignancy | Ckd-Mbd | ADPKD | Bone Marrow Transplant Complications | CKD (Chronic Kidney Disease) Stage 5D

Italy
Fondazione Policlinico Universitario Agostino Gemelli...
Fondazione Umberto Veronesi

Not yet recruiting

Development and Validation of a Risk Prediction Model for Venous Thromboembolism in Gynecological Cancer Patients Undergoing Systemic Antineoplastic Treatment: The Gynecological Cancer Associated Thrombosis (GynCAT) Study (GynCAT)

Gynecologic Cancer | Ovarian Cancer | Venous Thromboembolism | Cervix Cancer | Endometrial Cancer | Vaginal Cancer | Cancer-associated Thrombosis

Italy
Xiaoyan Jia

Recruiting

Neutrophil Gelatinase-associated Lipocalin VS Vascular Calcification in Maintenance Hemodialysis Patients (NGAL)

Chronic Kidney Disease-Mineral and Bone Disorder

China
Indiana University

Recruiting

Late Subclinical Cardiovascular Disease in Testicular Cancer Survivors

Coronary Artery Disease | Cisplatin Adverse Reaction | Lipid Disorder | Survivorship | Hypogonadism, Male | Testicular Cancer | Bone Marrow Transplant Complications | ASCVD

United States
University of Washington
Seattle Children's Hospital

Recruiting

Spinal Stimulation and Mobility Devices

Stroke | Cerebral Palsy | Premature Birth | Hypoxic-Ischemic Encephalopathy | Periventricular Leukomalacia

United States
Chang Gung Memorial Hospital

Recruiting

Epidemiological Study of Fabry Disease Screening in Chronic Kidney Disease Patients

Fabry Disease

Taiwan
Gdansk University of Physical Education and Sport
Pomeranian Medical University Szczecin; Medical University of Gdansk; University...

Recruiting

HIIT vs MICT During Pregnancy and Health and Birth Outcomes in Mothers and Children (HIIT MAMA)

Depression | Back Pain | Urinary Incontinence | Pregnancy | Anxiety | Body Composition | Cognitive Function | Pelvic Floor Disorders | Noncommunicable Diseases | Physical Fitness | Metabolism | Postpartum | Health Status | Pregnancy Induced Hypertension | Pain Threshold | Childbirth | Diabetes Mellitus, Gestational | Biomecha...

Poland
Melbourne Health

Recruiting

Venetoclax in Combination With Non-myeloablative Conditioning Allogeneic Haematopoietic Stem Cell Transplantation (VICTORY)

Myelodysplastic Syndromes | Leukemia, Myeloid, Acute | Plasma Cell Myeloma | Non-hodgkin Lymphoma | Leukemia, Lymphoblastic, Acute, L1 | Leukemia, Lymphoblastic, Acute, L2

Australia
Genmab

Recruiting

GEN3014 Safety Trial in Relapsed or Refractory Hematologic Malignancies

Acute Myeloid Leukemia (AML) | Diffuse Large B Cell Lymphoma (DLBCL) | Relapsed or Refractory Multiple Myeloma (RRMM)

United States, Korea, Republic of, Netherlands, Denmark, Australia, New Zealand, Poland, Spain, Sweden, Czechia, Malaysia, Greece, Moldova, Republic of, Georgia, Ukraine, France, Hungary, North Macedonia, Bosnia and Herzegovina and more
Newave Pharmaceutical Inc

Recruiting

Study of Oral Administration of LP-168 in Patients With Relapsed or Refractory B-cell Malignancies.

Follicular Lymphoma | Waldenstrom Macroglobulinemia | Mantle Cell Lymphoma | Marginal Zone Lymphoma | Diffuse Large B Cell Lymphoma | Hairy Cell Leukemia | CLL/SLL

United States
Zhejiang University
Yake Biotechnology Ltd.

Recruiting

CAR-T Cells Combined With Dasatinib for Patients With Relapsed and/or Refractory B-cell Hematological Malignancies

Acute Lymphoblastic Leukemia, in Relapse | Multiple Myeloma in Relapse | Multiple Myeloma, Refractory | Non-Hodgkin's Lymphoma, Relapsed | Non-Hodgkin's Lymphoma Refractory | Acute Lymphocytic Leukaemia Refractory

China
National Taiwan University Hospital

Recruiting

Multimodal Biomarkers for Diagnosis and Prognosis in CAA (CAA)

Alzheimer Disease | Intracranial Hemorrhages | Cerebral Amyloid Angiopathy

Taiwan
Fundación Instituto de Estudios de Ciencias de...
Instituto de Investigación Biomédica de Salamanca; Instituto de Salud Carlos...

Recruiting

Cardiovascular Prevention Strategies in Elderly Patients With Cancer (CARTIER Clinical Trial) (CARTIER)

Elderly | Cardiotoxicity | Antineoplastic Agents | Cancer (Colon Cancer, Breast Cancer, Lymphoma, Chronic Lymphoma Leukemia, Multiple Myeloma)

Spain
National Cancer Institute (NCI)

Recruiting

Nivolumab and Ipilimumab in Treating Patients With HIV Associated Relapsed or Refractory Classical Hodgkin Lymphoma or Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery

HIV Infection | Advanced Malignant Solid Neoplasm | Kaposi Sarcoma | Lung Carcinoma | Metastatic Malignant Solid Neoplasm | Unresectable Solid Neoplasm | Anal Carcinoma | Recurrent Classic Hodgkin Lymphoma | Refractory Classic Hodgkin Lymphoma

United States, Australia
North Sichuan Medical College
University of Glasgow; Afﬁliated Hospital of North Sichuan Medical College; Nanchong...

Completed

Evaluating the Potential of Large Language Models for Respiratory Disease Consultations (EPLLMMRDC)

Pneumonia | Bronchiectasis | Asthma | Pulmonary Fibrosis | Lung Cancer | Tuberculosis | Acute Upper Respiratory Infection | Pulmonary Embolism | Hay Fever | Acute Bronchitis

China
Lawson Health Research Institute
Alexion Pharmaceuticals, Inc.

Active, not recruiting

Paroxysmal Nocturnal Hemoglobinuria in ESUS & ETUS

Transient Ischemic Attack | Paroxysmal Nocturnal Hemoglobinuria | Cerebral Vein Thrombosis | Embolic Stroke of Undetermined Source

Canada
Ryazan State Medical University

Completed

Associations of Combinations of Single-nucleotide Polymorphisms in Women With Premature Ovarian Failure

Cardiovascular Diseases | Coronary Disease | Arrhythmias, Cardiac | Primary Ovarian Insufficiency | Menopause, Premature | Pulmonary Embolism | Polymorphism, Single Nucleotide

Russian Federation
Genetic Disease Investigators

Completed

Head Circumference Growth in Children With Ehlers-Danlos Syndrome Who Develop Dysautonomia Later in Life

Venous Insufficiency | Postural Orthostatic Tachycardia Syndrome | Dysautonomia | Ehlers Danlos Syndrome | External Hydrocephalus

United States
Plasmacure
Diabetes Fonds; Pathology and Medical Microbiology

Active, not recruiting

PLASOMA Ultimate Safety & Efficacy Study (PULSE)

Diabetic Foot Ulcer | Venous Leg Ulcer | Burn Wound | Pressure Ulcer | Skin Graft | Infected Surgical Wound | Skin Flap

Netherlands
Westlake University
Beijing Obstetrics and Gynecology Hospital

Completed

B-vitamin Levels and Adverse Pregnancy Outcomes

Pregnancy Complications | Preterm Birth | Gestational Diabetes | Pregnancy Loss | Recurrent Pregnancy Loss | Birth Defect | Gestational Hypertension | Pregnancy Induced Hypertension | Health Problems in Pregnancy

China
Stanford University
Alagille Syndrome Alliance

Enrolling by invitation

Decreasing Hemorrhage Risk in Children With Alagille Syndrome

Alagille Syndrome | Acquired Von Willebrand Disease | Pulmonary Artery Stenoses

United States
Juno Therapeutics, a Subsidiary of Celgene

Terminated

Long-term Follow-up Study for Patients Previously Treated With a Juno CAR T-Cell Product

Follicular Lymphoma | Multiple Myeloma | Mantle Cell Lymphoma | Chronic Lymphocytic Leukemia | Non Hodgkin Lymphoma | Diffuse Large B Cell Lymphoma

United States
Professor Adrian Covic
Medical Sciences Academy - Romania; Victor Babes Clinical Hospital of Infectious...

Unknown

Integrated Distance Management Strategy for Patients With Cardiovascular Diseases in the Context of COVID-19 (eCardioCovid19)

Coronary Artery Disease | Hypertension | Covid-19 | Angina Pectoris | Acute Coronary Syndrome | Heart Failure, Systolic | Depression, Anxiety | Coronary Syndrome | Stent Restenosis | Angioplasty | Isolation, Social

Romania

Clinical Trials on Spinal+Muscular+Atrophy

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Drug Interventions

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