Clinical Trials on Stable Atherothrombotic Disease in United Kingdom

Total 147141 results

Roswell Park Cancer Institute

Not yet recruiting

Pembrolizumab and Autologous Dendritic Cells for the Treatment of Refractory Colorectal Cancer (CRC)

Recurrent Colorectal Carcinoma | Stage IV Colorectal Cancer AJCC v8 | Stage III Colorectal Cancer AJCC v8 | Unresectable Colorectal Carcinoma | Metastatic Microsatellite Stable Colorectal Carcinoma

United States
Yale University

Recruiting

LIVEBETTER: A Trial Comparing Medications in Older Adults With Stable Angina and Multiple Chronic Conditions (LIVEBETTER)

Angina | Stable Ischemic Heart Disease

United States
East Carolina University
Gilead Sciences

Withdrawn

Efficacy of Ranolazine in Patients With Chronic Total Occlusions of Coronary Arteries

Myocardial Ischemia | Coronary Artery Disease | Arteriosclerosis | Chronic Stable Angina

United States
University of Washington
John L. Locke Jr. Charitable Trust

Terminated

Text Message Intervention to Improve Cardiac Rehab Participation

Myocardial Infarction | Percutaneous Coronary Intervention | Coronary Artery Bypass Surgery | Chronic Stable Angina | Left Ventricular Assist Device | Heart Transplant | Chronic Stable Heart Failure | Heart Valve Repair or Replacement

United States
Imperial College London

Enrolling by invitation

Smart Watch Insights for Prevention of Exacerbations and Enhance Rehabilitation - Movement Study (SWIPER-MOVES)

Cardiovascular Diseases | Diabetes | Respiratory Disease | Non-Alcoholic Fatty Liver Disease

United Kingdom
Laminate Medical Technologies

Completed

A Multi Center, Study to Evaluate the Safety and Efficacy of the VasQ External Support Device for Arteriovenous Fistulas

End Stage Renal Disease | Vascular Access

United Kingdom, Israel
Henry Ford Health System

Completed

Readiness for Behavior Change After a Heart Attack (ENROLL)

Myocardial Infarction | Coronary Artery Disease | Stable Angina

United States
LifeBridge Health

Unknown

Pharmacokinetics and Pharmacodynamics of Ticagrelor in Patients With Stable Angina, NSTEMI and STEMI Undergoing PCI

Myocardial Infarction | Coronary Artery Disease | Cardiovascular Disease | Stable Angina

United States
Atlantia Food Clinical Trials
Caelus Pharmaceuticals BV

Completed

Efficacy and Safety of 12-weeks Supplementation of Eubacterium Hallii on Insulin Sensitivity and Glycaemic Control

Glucose Metabolism Disorders | Metabolic Syndrome | Insulin Resistance | Impaired Glucose Tolerance | Insulin Sensitivity | Pre Diabetes

Ireland, United States, United Kingdom
University of Exeter
University of Bristol; University of Dundee

Withdrawn

Autoimmune Diabetes Accelerator Prevention Trial (adAPT)

Prediabetic State

United Kingdom
AstraZeneca

Completed

Assess Safety & Efficacy of Selumetinib When Given in Combination With Standard First Line Treatment for Advanced Non-small Cell Lung Cancer (SELECT-3)

Locally Advanced or Metastatic NSCL Cancer Stage IIIB IV

United Kingdom
University of California, San Francisco

Completed

Comparing the Efficacy of Ultravate Ointment in Combination With Lac-Hydrin Lotion in the Treatment of Psoriasis

Stable Plaque Psoriasis

United States
University Hospital Southampton NHS Foundation...
Bristol-Myers Squibb; Cancer Research UK; Institute of Cancer Research, United...

Completed

The Addition of Ipilimumab to Carboplatin and Etoposide Chemotherapy for Extensive Stage Small Cell Lung Cancer (ICE)

Extensive Stage Small Cell Lung Cancer

United Kingdom
Sidney Kimmel Comprehensive Cancer Center at Johns...
Bristol-Myers Squibb; Bayer

Active, not recruiting

Study of PI3Kinase Inhibition (Copanlisib) and Anti-PD-1 Antibody Nivolumab in Relapsed/Refractory Solid Tumors With Expansions in Mismatch-repair Proficient (MSS) Colorectal Cancer

Colon Cancer | Unresectable or Metastatic Microsatellite Stable (MSS) Solid Tumor Along With Microsatellite Stable (MSS) Colon Cancer

United States
University of Minnesota
Fairview Health Services

Completed

Mindfulness & Stress Management Study for Cardiac Patients

Myocardial Infarction | Heart Diseases | Heart Failure | Coronary Artery Bypass | Chronic Stable Angina | Angioplasty

United States
Mayo Clinic

Completed

CD-NP in Subjects With Stable Chronic Heart Failure (CD-NP)

Stable Chronic Heart Failure

United States
Novozymes A/S
Biofortis, Merieux NutriSciences

Completed

Clinical Trial to Evaluate the Efficacy and Safety of the Probiotic Strains Limosilactocillus Reuteri DSM 32910 and Lacticaseibacillus Paracasei DSM 32851 on Glucose Homeostatis in Prediabetic Adults (NOVOGLUCOSE)

Prediabetic State | Dysglycemia

United Kingdom, France, Romania
University of Florida

Completed

Impact of Ranolazine in Blood Markers in Women With Angina and Metabolic Syndrome (IRMA)

Metabolic Syndrome | Stable Angina

United States
Brigham and Women's Hospital

Recruiting

The Impact of Pcsk-9 Inhibition on PET CFR in Patients at High CV Risk (EMPOWER)

Stable Coronary Disease

United States
University of Leeds
University of Nottingham; University of Sheffield; Newcastle University; University... and other collaborators

Active, not recruiting

AREG, EREG and EGFR: Response to Anti-EGFR Agents in Colorectal Cancer

Colorectal Cancer Stage IV

United Kingdom
Regeneron Pharmaceuticals

Completed

COVID-19 Study to Assess Immunogenicity, Safety, and Tolerability of Moderna mRNA-1273 Vaccine Administered With Casirivimab+Imdevimab in Healthy Adult Volunteers

Healthy | Chronic Stable Illness

United States
Sandoz
Hexal AG

Completed

Study to Demonstrate Equivalent Efficacy and to Compare Safety of Biosimilar Etanercept (GP2015) and Enbrel (EGALITY)

Chronic Stable Plaque Psoriasis

Germany, Romania, Bulgaria, Czech Republic, Estonia, Hungary, Poland, Russian Federation, Slovakia, South Africa, Ukraine, United Kingdom
University College, London
Lund University; University Hospital, Bordeaux; Ludwig-Maximilians - University... and other collaborators

Completed

Care for Late Stage Parkinsonism (CLaSP)

Parkinson's Disease | Late Stage Parkinson's Disease

Netherlands, United Kingdom, Germany, France, Portugal, Sweden
Robert J. Porte
King's College Hospital NHS Trust; Universitaire Ziekenhuizen KU Leuven; Erasmus... and other collaborators

Completed

Dual Hypothermic Oxygenated Perfusion of DCD Liver Grafts in Preventing Biliary Complications After Transplantation (DHOPE-DCD)

End Stage Liver Disease | Liver Failure | Biliary Tract Diseases

Netherlands, Belgium, United Kingdom
TME Pharma AG

Completed

Lexaptepid Pegol (NOX-H94) in ESA-hyporesponsive Anemia in Dialysis Patients

Anemia | End Stage Renal Disease

United Kingdom, Germany, Italy
Mannkind Corporation

Completed

A Study Designed to Determine if the Drugs Albuterol (Salbutamol) and Fluticasone Have an Effect on the Pharmacokinetics of the Investigational Product Technosphere® Insulin Inhalation Powder in Healthy Volunteers

Diabetes Mellitus | Healthy Subjects

United Kingdom
Sanofi

Terminated

A Dose Titration Study to Assess the Effects of SAR407899 in Patients With MVA and/or Persistent Stable Angina Despite Angiographically Successful PCI

Microvascular Coronary Artery Disease

United States, Denmark, Korea, Republic of, Netherlands, Sweden
National Cancer Institute (NCI)

Recruiting

Testing the Combination of the Anti-Cancer Drugs Temozolomide and M1774 to Evaluate Their Safety and Effectiveness

Advanced Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm | Stage IV Colorectal Cancer AJCC v8 | Stage III Colorectal Cancer AJCC v8 | Metastatic Microsatellite Stable Colorectal Carcinoma | Advanced Microsatellite Stable Colorectal Carcinoma | Hematopoietic and Lymphatic System...

United States
University of California, San Francisco

Completed

Safety and Efficacy Study of Combination Treatment With Excimer Laser, Clobex Spray, and Vectical Ointment in the Treatment of Psoriasis

Chronic Stable Plaque Psoriasis

United States
University Hospital Birmingham NHS Foundation Trust

Completed

Steroid Impregnated Tape in the Treatment of Over-granulating Peritoneal Dialysis Exit Sites (STOP)

Peritoneal Dialysis | Chronic Renal Failure | End Stage Renal Failure | Continuous Ambulatory Peritoneal Dialysis

United Kingdom
MedImmune LLC

Completed

A Study to Evaluate the Immunogenicity of Quadrivalent LAIV (MEDI8662) in Adults 18 to 49 Years of Age (MI-CP206)

Healthy or Stable Underlying Chronic Medical Condition

United States
Prexton Therapeutics

Completed

A Phase I, Double Blind, Placebo Controlled, First in Human, Single and Multiple Ascending Oral Dose, Safety, Tolerability and Pharmacokinetic Study in Healthy Male and Female Subjects

Parkinson's Disease

United Kingdom
Tasly Pharmaceuticals, Inc.

Completed

Phase II Multi-Center Study of T89 to Treat Chronic Stable Angina (T89 phase 2)

Angina Pectoris

United States
Sidney Kimmel Comprehensive Cancer Center at Johns...
Merck Sharp & Dohme LLC

Active, not recruiting

Study of MK-3475 (Pembrolizumab) in Patients With Microsatellite Unstable (MSI) Tumors (Cohort D)

High Tumor Mutation Burden | High TMB (Tumor Mutation Burden) | MSS (Microsatellite Stable)

United States
Regeneron Pharmaceuticals

Completed

COVID-19 Study Assessing the Safety and Tolerability of Co-Formulated Anti-Spike (S) SARS-CoV-2 Monoclonal Antibodies (Casirivimab+Imdevimab) in Adult Volunteers

Healthy | Chronic Stable Illness

United States
ROM Technologies, INC

Recruiting

Integration of Telemedicine and Home-Based Cardiac Rehabilitation: Feasibility, Efficacy, and Adherence

Myocardial Infarction | Heart Failure | Coronary Artery Bypass | Stable Angina | Cardiac Rehabilitation | Valve Disease, Heart | Percutaneous Transluminal Coronary Angioplasty | Stent

United States
Amgen

Completed

Treadmill Cardiovascular Safety Study of Erenumab (AMG 334)

Stable Angina

United States, New Zealand, Slovakia, Czechia, South Africa, Switzerland, Bulgaria, Poland, Latvia, Romania
Alexza Pharmaceuticals, Inc.
Atlanta Center for Medical Research

Completed

Staccato Loxapine Multidose PK

Volunteers on Chronic, Stable Antipsychotic Regimens

United States
Takeda

Terminated

Effect of Febuxostat Compared to Placebo on Exercise Tolerance in Participants With Chronic Stable Angina

Angina

United States
University of Leicester

Recruiting

Usability and Acceptability Study of the P-STEP Mobile Application

Heart Failure | Chronic Obstructive Pulmonary Disease | Asthma | Type 2 Diabetes | Coronary Heart Disease | Interstitial Lung Disease

United Kingdom
AstraZeneca
Parexel

Recruiting

AZD7798 Safety, Tolerability, and Pharmacokinetics After a Single Ascending and Repeat Dose Administrations to Healthy Subjects, and Patients With Crohn's Disease

Healthy Subjects | Crohns Disease

United Kingdom
University of Oxford
Merck Sharp & Dohme LLC

Completed

Treatment of HDL to Reduce the Incidence of Vascular Events HPS2-THRIVE (HPS2-THRIVE)

Cardiovascular Disease | Diabetes Mellitus | Peripheral Arterial Disease | Coronary Heart Disease

United Kingdom
University of Leeds
The Leeds Teaching Hospitals NHS Trust

Recruiting

Evaluating Treatable Traits Across the Spectrum of Chronic Obstructive Airways Disease

Airway Disease

United Kingdom
University of Edinburgh

Recruiting

Innate Immunity in COPD

Chronic Obstructive Pulmonary Disease

United Kingdom
Imperial College London

Withdrawn

Endotoxin and Inflammatory Markers in Healthy Non-Smokers and Current Smokers Including Patients With Chronic Obstructive Pulmonary Disease (COPD)

Chronic Obstructive Pulmonary Disease

United Kingdom
King's College Hospital NHS Trust
University of Brighton

Completed

The Effects of a Home Exercise Video Programme for Patients With COPD

Chronic Obstructive Pulmonary Disease (COPD)

United Kingdom
University of Hull

Recruiting

PREhabilitation in Patients Awaiting Acute Inpatient Cardiac SurgEry ((PREP-ACE))

Coronary Artery Disease | Aortic Valve Disease | Endocarditis | Cardiac Disease | Valve Heart Disease

United Kingdom
Guy's and St Thomas' NHS Foundation Trust

Completed

The Role of HNHF to Improve Clinical Outcomes Following Severe AECOPD

Chronic Obstructive Pulmonary Disease

United Kingdom
Guy's and St Thomas' NHS Foundation Trust

Completed

NRD to Predict COPD Exacerbations at Home

Chronic Obstructive Pulmonary Disease

United Kingdom
Philips Respironics

Completed

Evaluating Forced Oscillation Technique (FOT) in Abolishing Flow Limitation

Chronic Obstructive Pulmonary Disease

United Kingdom

Clinical Trials on Stable Atherothrombotic Disease in United Kingdom

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