Clinical Trials on Stage 4 Cancer

Total 56097 results

American College of Radiology
RTOG Foundation, Inc.

Recruiting

Testing the Safety of Giving a Standard Dose of Radiation Over a Shorter Period of Time for Patients Who Had Surgery for Intermediate-Risk Head and Neck Cancer

Head and Neck Cancer | Head and Neck Squamous Cell Carcinoma | Squamous Cell Carcinoma of the Larynx | Squamous Cell Carcinoma of the Oral Cavity | Squamous Cell Carcinoma of the Oropharynx

United States
University of British Columbia

Recruiting

Biomarker Verification in Pediatric Chronic GvHD: ABLE 2.0 / PTCTC GVH 1901 Study

Leukemia | Allogeneic Hematopoietic Stem Cell Transplantation | Blood Cancer | Chronic Graft-versus-Host-Disease | Non-Malignant Hematologic and Lymphocytic Disorder

United States, Canada
Fondazione Policlinico Universitario Agostino Gemelli...

Recruiting

PROtocol of Metabolic and Cryptogenic livEr Disease regisTry for intEgration of Omic Studies (PROMETEO)

Obesity | Diabetes | Fatty Liver | Metabolic Syndrome | Cirrhosis | NASH - Nonalcoholic Steatohepatitis | Liver Cancer | NAFLD - Nonalcoholic Fatty Liver Disease | HCC - Hepatocellular Carcinoma

Italy
University of California, San Francisco

Recruiting

UCSF PANC Cyst Registry (UCSF PCR)

Pancreatic Neoplasms | Pancreatic Cancer | Pancreatic Diseases | Pancreatic Ductal Adenocarcinoma | Pancreatic Cyst | Intraductal Papillary Mucinous Neoplasm | Mucinous Cyst | Pancreatic Intraductal Papillary Mucinous Neoplasm

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Completed

Mirvetuximab Soravtansine and Gemcitabine Hydrochloride in Treating Patients With FRalpha-Positive Recurrent Ovarian, Primary Peritoneal, Fallopian Tube, Endometrial, or Triple Negative Breast Cancer

Recurrent Fallopian Tube Carcinoma | Recurrent Ovarian Carcinoma | Recurrent Primary Peritoneal Carcinoma | Recurrent Uterine Corpus Carcinoma | Recurrent Breast Carcinoma | Triple-Negative Breast Carcinoma

United States
SpringWorks Therapeutics, Inc.

Active, not recruiting

Nirogacestat in Ovarian Granulosa Cell Tumors

Ovarian Cancer | Ovarian Granulosa Cell Tumor | Ovarian Granulosa-Stromal Tumor

United States, Canada, Poland
University of Bordeaux

Completed

Delay to Diagnosis in Digestive Cancerology by the General Practitioner Related to Covid-19 Pandemic Confinement

Advanced Cancer | Pandemic, COVID-19 | Diagnosis | Neoplasms, Colorectal | Neoplasms Pancreatic | General Practitioner | Neoplasm, Liver

France
Giulio Stefanini
Agenzia Italiana del Farmaco

Active, not recruiting

Cardioprotective Effects of Nebivolol Versus Placebo in Patients Undergoing Chemotherapy With Anthracyclines (CONTROL)

Lymphoma, Large B-Cell, Diffuse | Breast Cancer | Chemotherapy Effect | Cardiotoxicity | Left Ventricular Dysfunction

Italy
Laboratório de Pesquisa em Lazer e Atividade Física
Centro de Pesquisas Oncológicas

Completed

Pilates and Dance to Breast Cancer Patients Undergoing Treatment

Quality of Life | Pain | Breast Cancer | Fatigue | Lymphedema | Stress | Sleep Disturbance | Depressive Symptoms | Range of Motion | Body Image | Cardiorespiratory Fitness | Postural Balance | Self Esteem | Sexual Function Disturbances | Muscular Weakness | Optimism

Brazil
Charite University, Berlin, Germany

Unknown

Subjective Near-infrared Fluorescence Guidance in Perfusion Assessment of Ileal Pouch Formation and Ileal-pouch-anal Anastomosis

Colorectal Cancer | Crohn Disease | Ulcerative Colitis | Familial Adenomatous Polyposis | Crohn Colitis | Ileal Pouch

Germany
University of Florida

Withdrawn

Impact of Early Implementation of Narrative Medicine Techniques on Patient Centered Attitudes of Medical Students

Diabetes Mellitus | Hematologic Diseases | Cancer | Chronic Disease | Cystic Fibrosis | Narrative Medicine | Terminal Illness | Rheumatologic Disorder | Oncologic Disorders

United States
Merck Sharp & Dohme LLC

Completed

Multivalent HPV (Human Papillomavirus) Vaccine Study in 16- to 26-Year Old Men and Women (V503-003)

Anal Cancer | Genital Warts | Anal Intraepithelial Neoplasia
Maimónides Biomedical Research Institute of Córdoba

Completed

Role of Intraperitoneal Intraoperative Chemotherapy With Paclitaxel in the Surgical Treatment of Peritoneal Carcinomatosis From Ovarian Cancer. Hyperthermia Versus Normothermia

Peritoneal Carcinomatosis
VA Office of Research and Development
Baylor College of Medicine

Completed

A Culturally Sensitive Values-Guided Aid for End of Life Decision-Making (Aim3)

Chronic Obstructive Pulmonary Disease | Lung Cancer | Chronic Kidney Disease | Cirrhosis | Congestive Heart Failure | Colon Carcinoma

United States
CSA Medical, Inc.
Reset Medical, Inc.

Withdrawn

CryoSpray Ablation(tm)Thoracic Patient Registry

Asthma | Emphysema | Lung Cancer | Mesothelioma | COPD | Sarcoidosis | Chronic Bronchitis
National Taiwan University Hospital

Unknown

Retrospective Study of Ovarian Cancer Patients With Brain Metastasis

Ovarian Cancer | Brain Metastases

Taiwan
St. Jude Children's Research Hospital

Completed

Recombinant Human Thrombopoietin in Children Receiving Ifosfamide, Carboplatin, and Etoposide Chemotherapy

Osteosarcoma | Neuroblastoma | Rhabdomyosarcoma | Hepatic Cancer | Germ Cell Tumors

United States
Ankara Medipol University

Completed

The Effects of Creative Dance Therapy on Motor and Executive Functions in Children With Dyslexia

Motor Skills | Dyslexia | Executive Function | Dance Therapy

Turkey
University of Nottingham

Unknown

Effectiveness of Acceptance and Commitment Therapy Self-Help for Carers of People With Multiple Sclerosis

Carer Stress Syndrome

United Kingdom
University of North Carolina, Chapel Hill
American Cancer Society, Inc.

Completed

Sharing Our Strength: A Research Study for Bone Marrow/Stem Cell Transplant Survivors

Leukemia | Multiple Myeloma | Acute Leukemia | Psychological Distress | Acute Lymphocytic Leukemia | Hematological Cancers

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute...

Completed

Low-Dose Total Body Irradiation and Donor Peripheral Blood Stem Cell Transplant Followed by Donor Lymphocyte Infusion in Treating Patients With Non-Hodgkin Lymphoma, Chronic Lymphocytic Leukemia, or Multiple Myeloma

Stage II Multiple Myeloma | Stage III Multiple Myeloma | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma and other conditions

United States, Germany, Italy
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Fludarabine Phosphate, Low-Dose Total-Body Irradiation, and Donor Stem Cell Transplant Followed by Cyclosporine, Mycophenolate Mofetil, Donor Lymphocyte Infusion in Treating Patients With Hematopoietic Cancer

Stage II Multiple Myeloma | Stage III Multiple Myeloma | Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Juvenile Myelomonocytic Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult... and other conditions

United States, Italy
Seagen Inc.

Recruiting

A Study of SGN-B6A in Advanced Solid Tumors

Uterine Cervical Neoplasms | Stomach Neoplasms | Urinary Bladder Neoplasms | Ovarian Neoplasms | Squamous Cell Carcinoma of Head and Neck | Carcinoma, Non-Small Cell Lung | Esophageal Adenocarcinoma | Esophageal Squamous Cell Carcinoma | Gastroesophageal Junction Adenocarcinoma | HER2 Negative Breast Neoplasms and other conditions

United States, Spain, United Kingdom, France, Switzerland
Scripps Health

Completed

Nonmyeloablative Allogeneic Transplant (Mini-allo)

Melanoma | Sarcoma | Renal Cell Carcinoma | Breast Cancer | Multiple Myeloma | Hodgkin's Lymphoma | Non-Hodgkin's Lymphoma | Ovarian Cancer | Thymoma | Waldenstrom Macroglobulinemia | Mantle Cell Lymphoma | Chronic Lymphocytic Leukemia | Myelodysplastic Syndrome | Acute Lymphocytic Leukemia | Acute Myelogenous Leukemia | Chronic Myelogenous Leukemia and other conditions

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Alemtuzumab and Glucocorticoids in Treating Newly Diagnosed Acute Graft-Versus-Host Disease in Patients Who Have Undergone a Donor Stem Cell Transplant

Lymphoma | Myelodysplastic Syndromes | Leukemia | Testicular Germ Cell Tumor | Breast Cancer | Chronic Myeloproliferative Disorders | Ovarian Cancer | Gestational Trophoblastic Tumor | Neuroblastoma | Multiple Myeloma and Plasma Cell Neoplasm | Myelodysplastic/Myeloproliferative Diseases | Graft Versus Host...

United States
China Cardiovascular Association
Peking University; Peking University First Hospital; Shanghai Zhongshan Hospital

Unknown

Clinical Features, Treatment Mode and Health Outcomes of Chest Pain Patients in China (CHANGE) (CHANGE)

STEMI - ST Elevation Myocardial Infarction | Chest Pain Center
CytoSorbents, Inc

Recruiting

CytOSorb TreatMent Of Critically Ill PatientS Registry (COSMOS)

Sepsis | Burns | Septic Shock | Trauma | Infectious Disease | Pancreatitis | Acute Respiratory Distress Syndrome | Liver Transplant; Complications | Drug Overdose | Acute Liver Failure | Cardiogenic Shock | Rhabdomyolysis | Acute on Chronic Liver Failure | Hemophagocytic Lymphohistiocytoses | Extracorporeal Life Support and other conditions

Spain, Italy, Germany, Portugal
Hereditary Neuropathy Foundation

Recruiting

Natural History Study for Charcot Marie Tooth Disease

Charcot-Marie-Tooth Disease | Charcot-Marie-Tooth Disease, Type IA | Charcot-Marie-Tooth Disease Type 2A | Charcot-Marie-Tooth | Charcot-Marie-Tooth Disease, Type IB | Charcot-Marie-Tooth Disease Type 2 | Charcot-Marie-Tooth Disease, Type 2C | Charcot-Marie-Tooth Disease Type 2A2B | Charcot-Marie-Tooth... and other conditions

United States
Vanderbilt-Ingram Cancer Center
National Cancer Institute (NCI); National Institutes of Health (NIH)

Terminated

T Cells in Predicting Acute Graft-Versus-Host Disease in Patients Undergoing Donor Stem Cell Transplant

Lymphoma | Myelodysplastic Syndromes | Leukemia | Testicular Germ Cell Tumor | Breast Cancer | Chronic Myeloproliferative Disorders | Ovarian Cancer | Gestational Trophoblastic Tumor | Neuroblastoma | Multiple Myeloma and Plasma Cell Neoplasm | Myelodysplastic/Myeloproliferative Neoplasms

United States
OHSU Knight Cancer Institute
National Cancer Institute (NCI)

Terminated

Moxifloxacin in Preventing Bacterial Infections in Patients Who Have Undergone Donor Stem Cell Transplant

Lymphoma | Myelodysplastic Syndromes | Leukemia | Testicular Germ Cell Tumor | Breast Cancer | Chronic Myeloproliferative Disorders | Ovarian Cancer | Gestational Trophoblastic Tumor | Neuroblastoma | Infection | Multiple Myeloma and Plasma Cell Neoplasm | Myelodysplastic/Myeloproliferative Neoplasms

United States
National Institutes of Health Clinical Center (CC)
National Cancer Institute (NCI)

Completed

Ravuconazole in Preventing Fungal Infections in Patients Undergoing Allogeneic Stem Cell Transplantation

Lymphoma | Myelodysplastic Syndromes | Leukemia | Testicular Germ Cell Tumor | Breast Cancer | Chronic Myeloproliferative Disorders | Ovarian Cancer | Gestational Trophoblastic Tumor | Neuroblastoma | Infection | Multiple Myeloma and Plasma Cell Neoplasm | Myelodysplastic/Myeloproliferative Neoplasms

United States
EMD Serono Research & Development Institute, Inc.
Merck KGaA, Darmstadt, Germany

Not yet recruiting

Tuvusertib Combined With Niraparib or Lartesertib in Participants With Epithelial Ovarian Cancer (DDRiver EOC 302)

Ovarian Cancer

United States, Germany
UNICANCER
GlaxoSmithKline; National Cancer Institute, France

Not yet recruiting

Dostarlimab for Locally Advanced or Metastatic Cancer (Non-colorectal/Non-endometrial) With Tumor dMMR/MSI (Pan-MSI-ACSE)

Soft Tissue Sarcoma | Pancreatic Adenocarcinoma | Gastric Adenocarcinoma | Neuroendocrine Carcinoma | Adrenocortical Carcinoma | Small Bowel Adenocarcinoma | Ampulla of Vater Carcinoma | Duodenum Adenocarcinoma

France
Erasmus Medical Center

Not yet recruiting

Fluorescence-guided Surgery in Laryngeal- and Hypopharyngeal Cancer: a Feasibility Trial (STELLAR)

Squamous Cell Carcinoma of the Larynx | Squamous Cell Carcinoma of the Hypopharynx

Netherlands
Cristian Deana

Recruiting

High Flow Nasal Cannula After Esophagectomy (OSSIGENA1V)

Esophageal Cancer | Postoperative Pneumonia | Postoperative Pulmonary Atelectasis | Postoperative Pneumothorax | Postoperative Infection of Incision | Postoperative Acute Myocardial Infarction

Italy
Seagen Inc.

Recruiting

A Study of SGN-BB228 in Advanced Melanoma and Other Solid Tumors

Colorectal Neoplasms | Pancreatic Neoplasms | Mesothelioma | Non-small Cell Lung Cancer | Cutaneous Melanoma

United States, Canada, Switzerland, France, Germany, United Kingdom
AP Biosciences Inc.

Not yet recruiting

A Study to Investigate the Safety, Pharmacokinetics, and Clinical Activity of AP203 in Patients With Locally Advanced or Metastatic Solid Tumors, and Expansion to Selected Malignancies (APT-CUBE)

Esophageal Squamous Cell Carcinoma (ESCC) | Locally Advanced or Metastatic Solid Tumors | Non Small Cell Lung Cancer (NSCLC) | Head and Neck Squamous Cell Carcinoma (HNSCC)
UNC Lineberger Comprehensive Cancer Center
National Cancer Institute (NCI)

Recruiting

Acceptability and Feasibility of Combination Treatment for Cervical Precancer Among South African Women Living With HIV (ACT2)

Cervical Cancer | Human Immunodeficiency Virus | Human Papillomavirus | CIN2 | CIN3

South Africa
The University of Hong Kong

Recruiting

The Long-term Spill-over Impact of COVID-19 on Health and Healthcare of People With Non-communicable Diseases

Cardiovascular Diseases | Hypertension | Diabetes Mellitus | Cancer | Kidney Disease, Chronic | Noncommunicable Diseases | Chronic Respiratory Disease

China
Centre Oscar Lambret

Recruiting

Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in Ovarian Cancer (CHIPPI) (CHIPPI)

Ovarian Cancer | Ovarian Carcinoma | Ovary Neoplasms

France, Belgium
University of Pennsylvania
Memorial Sloan Kettering Cancer Center; Susan G. Komen Breast Cancer Foundation

Enrolling by invitation

Polygenic Risk Scores and Multi-cancer Early Detection for Ovarian Cancer (PROMISE)

Ovarian Cancer | BRCA Mutation

United States
Oncoinvent AS

Active, not recruiting

Study of Radspherin® in Recurrent Ovarian Cancer Subjects With Peritoneal Carcinomatosis

Ovarian Cancer | Peritoneal Carcinomatosis

Belgium, Spain, Norway
Memorial Sloan Kettering Cancer Center
Bristol-Myers Squibb

Completed

A Study of Nivolumab in Selected Uterine Cancer Patients

Carcinosarcoma | Leiomyosarcoma | Endometrial Carcinoma | Uterine Cancer | Clear Cell Carcinoma | Undifferentiated Sarcoma | High Grade Endometrial Stromal Sarcoma

United States
Jason J. Luke, MD
Array BioPharma

Active, not recruiting

Study of ARRY-614 Plus Either Nivolumab or Nivolumab+Ipilimumab

Melanoma | Renal Cell Carcinoma | Solid Tumor | Non-small Cell Lung Cancer | Head and Neck Squamous Cell Carcinoma

United States
Duke University
United States Agency for International Development (USAID); Universidad Peruana...

Completed

Identification and Treatment of Cervical Abnormalities in Perú Through Integration of Pocket Colposcopy and Telemedicine

HIV Infections | Cervical Cancer | HPV Infection

Peru
Sumitomo Pharma America, Inc.

Completed

First-in-human Study of Oral TP-0903 (a Novel Inhibitor of AXL Kinase) in Patients With Advanced Solid Tumors

Advanced Solid Tumors | Recurrent Ovarian Carcinoma | Colorectal Carcinoma | EGFR Positive Non-small Cell Lung Cancer | BRAF-Mutated Melanoma

United States
Rain Oncology Inc

Withdrawn

Milademetan in Combination With Atezolizumab in Patients With Advanced Solid Tumors With CDKN2A Loss

Melanoma | Renal Cell Carcinoma | Gastric Cancer | NSCLC | Mesothelioma | Advanced Solid Tumor | Pancreas Adenocarcinoma | Urothelial Carcinoma Bladder | HNSCC | CDKN2A
National Cancer Institute (NCI)

Completed

Anti-PD-L1/TGF-beta Trap (M7824) Alone and in Combination With TriAd Vaccine and N-803 for Resectable Head and Neck Squamous Cell Carcinoma Not Associated With Human Papillomavirus Infection

Head and Neck Cancer | Head and Neck Neoplasms

United States
AstraZeneca
ImaginAb, Inc.

Terminated

A First-in-human Study to Evaluate the Safety and Tolerability of AZD8853 in Participants With Selected Advanced/Metastatic Solid Tumours

Carcinoma, Non-Small-Cell Lung | Urinary Bladder Neoplasms | Colorectal Cancer

United States, Canada
BioXcel Therapeutics Inc

Active, not recruiting

A Trial of BXCL701 and Pembrolizumab in Patients With mCRPC Either Small Cell Neuroendocrine Prostate Cancer or Adenocarcinoma Phenotype.

Prostate Cancer | Neuroendocrine Tumors | Small Cell Carcinoma

United States, United Kingdom

Clinical Trials on Stage 4 Cancer

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CROs in South Africa

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