Clinical Features, Treatment Mode and Health Outcomes of Chest Pain Patients in China (CHANGE) (CHANGE)

Clinical Features, Treatment Mode and Health Outcomes of Chest Pain Patients in China: China Chest Pain Center Accreditation Programme,CHANGE-chest Pain Research

Chinese Cardiovascular Association is an association dedicated to establishing Chest Pain Centers in hospitals that have basic qualifications and meet pre-designed quality control targets.The vision of Chinese Cardiovascular Association is the cardiovascular health of every Chinese, and the mission is to realize the early arrival of the inflection point of cardiovascular events in China.The institute of China Heart House is responsible for the daily management and implementation of Chinese Cardiovascular Association and the implementation and management of the Chest Pain Center construction project.In order to improve standard treatment and chest pain system management to achieve better outcomes for patients, China Heart House established the chest pain center database.The database includes patients in 4129 registered hospitals in 31 provinces in China who have been admitted with chest pain.The database can reflect the clinical characteristics, treatment and outcome of patients with chest pain in China.

This non-interventional, retrospective study analyzed the chest pain center database to understand the demographics, clinical characteristics, treatment patterns and clinical outcomes of patients with chest pain, and to analyze the effects of different treatment patterns, including chest pain centers and related collaborative treatment networks.The results of the study will assess the gap between the real-world situation and the recommendations of the guidelines and reflect the effect of chest pain centers and related collaborative treatment networks on the treatment process and service quality.The research results can be directly translated into the basis of medical treatment system intervention, and also provide decision-making reference for improving the certification standards and quality control of chest pain centers.

Study Overview

• Status: Unknown
• Conditions: STEMI - ST Elevation Myocardial Infarction; Chest Pain Center

• Study Type: Observational
• Enrollment (Anticipated): 50000

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years and older (Adult, Older Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

• Sampling Method: Probability Sample

Study Population

The study population was inpatients (18 years and older) admitted to the Chest Pain Central database with symptoms of chest pain.The database registration of this study was conducted in 4129 registered hospitals in 31 provinces in China.All hospitals participating in the Chest Pain Center program are encouraged to manage patients in accordance with local standard practices (as recommended by current Chinese guidelines).

This study will include data on all patients in the chest pain central database.

Description

Inclusion Criteria:

• age 18 and above
• patients admitted with chest pain
• diagnosis is made by the treating physician based on local practice and clinical judgment

Exclusion Criteria:

• No

Study Plan

How is the study designed?

Number of groups / cohorts

1

Cohorts and Interventions

Group / Cohort
Patients with Myocardial Infarction

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
mean and standard deviation of STEMI (ST-segment elevated Myocardial Infarction)patients	mean and standard deviation of STEMI patients	baseline
Proportion of STEMI (ST-segment elevated Myocardial Infarction)patients	Proportion of female STEMI patients	baseline
emergency information of STEMI patients	Path to hospital First medical contact time Does the patient circumvent emergency Telecardiogram transmission STEMI Reperfusion Therapy Initiation time of interventional surgery Catheter chamber activation time Time of arrival of patient in catheter room Guide wire passage time D2B time	baseline
admission status of STEMI patients	admission status of STEMI patients	baseline
hospitalization evaluation of STEMI patients	value of serum troponin and serum creatinin of STEMI patients	baseline
In-hospital mortality of STEMI patients	In-hospital mortality of STEMI patients	baseline
Hospitalization days of STEMI patients	Hospitalization days of STEMI patients	baseline
Total cost of STEMI patients	Total cost of STEMI patients	baseline

Collaborators and Investigators

• Sponsor: China Cardiovascular Association
• Collaborators: Peking University; Peking University First Hospital; Shanghai Zhongshan Hospital

Study record dates

Study Major Dates

• Study Start (Anticipated): July 1, 2019
• Primary Completion (Anticipated): August 1, 2019
• Study Completion (Anticipated): August 1, 2019

Study Registration Dates

• First Submitted: July 3, 2019
• First Submitted That Met QC Criteria: July 9, 2019
• First Posted (Actual): July 10, 2019

Study Record Updates

• Last Update Posted (Actual): July 10, 2019
• Last Update Submitted That Met QC Criteria: July 9, 2019
• Last Verified: July 1, 2019

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Ischemia; Pathologic Processes; Necrosis; Myocardial Ischemia; Heart Diseases; Cardiovascular Diseases; Vascular Diseases; Pain; Neurologic Manifestations; Myocardial Infarction; Infarction; ST Elevation Myocardial Infarction; Chest Pain
• Other Study ID Numbers: GUSU19005

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No