Clinical Trials on Steroid Synthesis Inhibitors

Total 839 results

University Hospital, Bordeaux

Not yet recruiting

Comparison of Therapeutic Strategies With Cholinesterase Inhibitors (SOS TRIAL)

Alzheimer Disease | Cholinesterase Inhibitors

France
Takeda

Completed

Safety and Pharmacokinetic Profile of Udenafil in Healthy Mexican Adults

Erectile Dysfunction | Phosphodiesterase 5 Inhibitor

Mexico
Novo Nordisk A/S

Completed

Efficacy and Safety of NNC 0078-0000-0007 in Patients With Congenital Haemophilia and Inhibitors (adept™2)

Congenital Bleeding Disorder | Haemophilia A With Inhibitors | Haemophilia B With Inhibitors

Taiwan, United Kingdom, Thailand, Serbia, Croatia, Italy, Poland, Romania, Hungary, Malaysia, United States, Austria, Brazil, Greece, Japan, Puerto Rico, Russian Federation, South Africa, Turkey
Novo Nordisk A/S

Completed

Efficacy of NovoSeven® in Bleeding Prophylaxis in Hemophilia

Congenital Bleeding Disorder | Haemophilia A With Inhibitors | Haemophilia B With Inhibitors

France, United States, Spain, Brazil, Philippines, South Africa, Poland, Turkey, Romania, Bulgaria, Russian Federation, Argentina
Alaa Gameil Abd El-salam Hussien
Assiut University

Active, not recruiting

Primary Patency in Pediatric Patients With Hemodialysis Access

The Aim of This Study is to Follow up Short Term "3-6 Months"& Mid Term" 6-12months "Outcomes of Vascular Access" Native and Synthetic "in ESRD Pediatrics

Egypt
AltruBio Inc.

Completed

Neihulizumab (ALTB-168) in Patients With Steroid-refractory Acute Graft-versus-host Disease or Treatment-refractory Acute Graft-versus-host Disease

Steroid-refractory Acute Graft-versus-Host Disease | Treatment-refractory Acute Graft-versus-Host Disease

United States
Jiangsu Gensciences lnc.

Completed

A Phase I of SS109 in Hemophilia A or and B With Inhibitors

Factor VII Deficiency | Hemophilia A With Inhibitor | Hemophilia B With Inhibitor

China
Gyeongsang National University Hospital

Completed

ACCEL-LOADING-ACS Study

Myocardial Reperfusion Injury | Platelet Aggregation Inhibitors | Anti-inflammatory Agent

Korea, Republic of
National Taiwan University Hospital

Unknown

High Dose Versus Standard Dose Proton Pump Inhibitor (PPI) in High-risk Bleeding Peptic Ulcers After Combined Endoscopic Treatment

Bleeding | Peptic Ulcer | Endoscopy | Proton Pump Inhibitors

Taiwan
Zhejiang University

Recruiting

A Clinical Study on the Analysis of Risk Factors for the Occurrence of PD-1/PD-L1 Inhibitor-associated Liver Injury in Lung Cancer Patients

Immune Checkpoint Inhibitors | Liver Injury

China
Montreal Heart Institute
Institut de Recherches Cliniques de Montreal

Recruiting

Assessing Pharmacokinetics and Pharmacodynamics of Daily Enteric-coated Aspirin in Patients With StablE Diabetes II (APPEASEDII)

Diabetes Mellitus, Type 2 | Type 2 Diabetes | Platelet Aggregation | Aspirin | Platelet Aggregation Inhibitors

Canada
Peking University People's Hospital

Recruiting

Prevalence and Risk Factors for Pain and Related Adverse Reactions Among Breast Cancer Survivors on Aromatase Inhibitors

Depression | Pain | Breast Cancer | Sleep | Anxiety | Aromatase Inhibitors | Endocrine Therapy

China
ECOG-ACRIN Cancer Research Group
National Cancer Institute (NCI)

Terminated

Infliximab and Intravenous Immunoglobulin Therapy in Treating Patients With Steroid-Refractory Pneumonitis

Hematopoietic and Lymphoid Cell Neoplasm | Malignant Solid Neoplasm | Steroid-Refractory Pneumonitis

United States
IRCCS Fondazione Stella Maris

Completed

Trehalose in Subjects With Neuronal Ceroid Lipofuscinoses (3AL-CLN36)

Neuronal Ceroid-Lipofuscinoses

Italy
University Hospital of Ferrara

Completed

Predischarge Bundle to Minimize Negative Impact on Quality of Life of Nuisance Bleedings (BATMAN)

Myocardial Ischemia | Quality of Life | Hemorrhage | Platelet Aggregation Inhibitors

Italy
Blueprint Medicines Corporation

Terminated

(HARMONY) Study of BLU-701 in EGFR-mutant NSCLC

Neoplasms | Respiratory Tract Diseases | Neoplasms by Histologic Type | Lung Diseases | Neoplasms by Site | Adenocarcinoma | Carcinoma | Carcinoma, Non-Small-Cell Lung | Respiratory Tract Neoplasms | Thoracic Neoplasms | Carcinoma, Bronchogenic | Bronchial Neoplasms | Neoplasms, Nerve Tissue | Non Small Cell Lung... and other conditions

United States
University of British Columbia
Johnson & Johnson Consumer Inc. (J&JCI); Genome British Columbia

Active, not recruiting

Epigenetic Health Benefits of Budesonide (Project Ace)

Environmental Exposure | Epigenetic Effects of Intranasal Steroids

Canada
David L Rogers, MD

Active, not recruiting

Intravitreal ERT to Prevent Retinal Disease Progression in Children With CLN2

Neuronal Ceroid Lipofuscinosis Type 2

United States
China Medical University Hospital

Completed

Yoga for Aromatase Inhibitor-related Knee Pain Relief in Breast Cancer Patients

Breast Cancer | Knee Pain | Yoga | Aromatase Inhibitor

Taiwan
Peking Union Medical College Hospital

Recruiting

The Efficacy and Safety of Corticosteroids in Combination With Ruxolitinib in the Management of Checkpoint Inhibitor Pneumonia

Severe Checkpoint Inhibitor Pneumonitis

China
StemCells, Inc.

Withdrawn

Safety and Efficacy Study of HuCNS-SC in Subjects With Neuronal Ceroid Lipofuscinosis

Neuronal Ceroid Lipofuscinosis

United States
Neurogene Inc.

Recruiting

A Natural History Study of Neuronal Ceroid Lipofuscinosis Type 5 (CLN5)

Ceroid Lipofuscinosis, Neuronal 5

United States
Hoffmann-La Roche

Active, not recruiting

A Study to Evaluate the Safety, Efficacy, Pharmacokinetics and Pharmacodynamics of Emicizumab in Participants With Mild or Moderate Hemophilia A Without FVIII Inhibitors (HAVEN 6)

Hemophilia A | Mild Hereditary Factor VIII Deficiency Disease Without Inhibitor | Moderate Hereditary Factor VIII Deficiency Disease Without Inhibitor

United States, Netherlands, Belgium, France, Germany, South Africa, Spain, Canada, United Kingdom, Poland
AryoGen Pharmed Co.

Completed

Prospective, Non-interventional Study to Evaluate Immunogenicity of AryoSeven

Factor VII Deficiency | Hemophilia A With Inhibitor | Hemophilia B With Inhibitor | Glanzmann's Thrombasthenia

Iran, Islamic Republic of
Novartis Pharmaceuticals

Terminated

Safety and Efficacy of INC280 and Buparlisib (BKM120) in Patients With Recurrent Glioblastoma

c-MET Inhibitor; PI3K Inhibitor, PTEN Mutations, Homozygous Del. of PTEN or PTEN Neg. by IHC, c-Met Ampli. by FISH, INC280, BKM120, Buparlisib; Recurrent GBM

Spain, Switzerland, Germany, United States, Netherlands
Samsung Medical Center

Recruiting

Imaging Biomarkers for Immune Checkpoint Inhibitor Treatment in Patients With Non-small Cell Lung Cancer (IBFIC)

Carcinoma, Non-Small-Cell Lung | Immune Checkpoint Inhibitors

Korea, Republic of
University Hospital Regensburg
ClinAssess GmbH

Unknown

A Phase II Trial on Treatment of Steroid-refractory Bronchiolitis Obliterans With Interferon Gamma 1b After Allogeneic SCT (IFN_BOSZT_01)

Steroid-refractory Bronchiolitis Obliterans

Germany
McGill University
Canadian Institutes of Health Research (CIHR)

Completed

Exogenous Ketosis During Bed Rest in Older Adults (KBR)

Muscle Atrophy | Cognitive Function | Muscle Protein Synthesis | Insulin Sensitivity | Muscle Strength | Functional Capacity | Physical Inactivity | Mitochondrial Function

Canada
Novo Nordisk A/S

Completed

Survey Evaluating the Psychosocial Effects of Living With Haemophilia (HERO)

Congenital Bleeding Disorder | Haemophilia A With Inhibitors | Haemophilia B With Inhibitors | Haemophilia A | Haemophilia B | Relatives to/Carers of Patients

Spain, Canada, United Kingdom
Novo Nordisk A/S

Completed

Impact of Pain on Functional Impairment and Quality of Life in Adults With Hemophilia

Congenital Bleeding Disorder | Haemophilia A With Inhibitors | Haemophilia B With Inhibitors | Haemophilia A | Haemophilia B

United States
Assistance Publique - Hôpitaux de Paris

Completed

Efficiency of Levamisole for Maintaining Remission After the First Flare of Steroid Sensitive Nephrotic Syndrome in Children (NEPHROVIR3)

First Manifestation of Steroid Sensitive Nephrotic Syndrome

France
Jessica Scherr
BioMarin Pharmaceutical

Enrolling by invitation

Examining Developmental Outcomes of Children Diagnosed With CLN2 Disease

Batten Disease | Neuronal Ceroid-Lipofuscinoses | CLN2

United States
Chang Gung Memorial Hospital

Completed

Efficacy and Safety of Kinesiology Tape Wrapping for Paronychia Induced by Epidermal Growth Factor Receptor Inhibitors

Paronychia | Epidermal Growth Factor Receptor Inhibitor

Taiwan
American Thrombosis and Hemostasis Network
LFB USA, Inc.

Recruiting

SEVENFACT® for Bleeding Events in Hemophilia With Inhibitors

Hemophilia A With Inhibitor | Hemophilia B With Inhibitor

United States
CSL Behring

Completed

Extension Study of Zemaira® i.v. Administration in Subjects With Emphysema Due to alpha1-proteinase Inhibitor Deficiency.

Emphysema | Alpha 1-proteinase Inhibitor Deficiency

Australia, Canada, Czech Republic, Denmark, Estonia, Finland, Germany, Ireland, Poland, Romania, Sweden
Chinese University of Hong Kong
Nanfang Hospital, Southern Medical University

Recruiting

PPI Infusion Versus Oral Acid Pump Inhibitors for Bleeding Peptic Ulcers

Proton Pump Inhibitors | Upper GI Bleeding

China
G.Gennimatas General Hospital
2nd Department of Cardiology, "Attikon" University Hospital, National and...

Not yet recruiting

Dapagliflozin to Prevent Atrial Fibrillation Recurrence After Transcatheter Pulmonary Venous Isolation.

Catheter Ablation | Atrial Fibrillation Recurrent | Sodium-glucose Co-transporter 2 Inhibitors | Pulmonary Venous Isolation

Greece
Rabin Medical Center

Recruiting

Intraocular Pressure in Children With Acute Lymphoblastic Leukemia (ALL) Treated With High Dose Steroids (ALL)

ALL, Childhood | Steroid-Induced Glaucoma

Israel
Susan Smyth

Completed

Early Use of Rosuvastatin in Acute Coronary Syndromes: Targeting Platelet-Leukocyte Interactions

Acute Coronary Syndrome | Angioplasty, Transluminal, Percutaneous Coronary | Hydroxymethylglutaryl-CoA Reductase Inhibitors | Blood Platelets

United States
Novo Nordisk A/S

Completed

Bioequivalence of NovoSeven® and a NovoSeven® Formulation Stable at Room Temperature in Healthy Male Subjects

Healthy | Congenital Bleeding Disorder | Haemophilia A With Inhibitors | Haemophilia B With Inhibitors | Acquired Bleeding Disorder | Acquired Haemophilia | Congenital FVII Deficiency | Glanzmann's Disease

France
Pharvaris Netherlands B.V.

Completed

Dose-ranging Study of Oral PHA-022121 for Acute Treatment of Angioedema Attacks in Patients With Hereditary Angioedema (RAPIDe-1)

Hereditary Angioedema | Hereditary Angioedema Type I | Hereditary Angioedema Type II | Hereditary Angioedema Types I and II | Hereditary Angioedema Attack | Hereditary Angioedema With C1 Esterase Inhibitor Deficiency | Hereditary Angioedema - Type 1 | Hereditary Angioedema - Type 2 | C1 Esterase Inhibitor... and other conditions

Bulgaria, United States, Spain, Israel, Germany, Canada, Czechia, France, Hungary, Italy, Netherlands, Poland, United Kingdom
Shaheed Zulfiqar Ali Bhutto Medical University

Recruiting

Comparison of Relapse Rate After 12 Weeks Verses 20 Weeks Steroid Therapy for the Management of First Episode of Steroid Sensitive Nephrotic Syndrome

Steroid-Sensitive Nephrotic Syndrome

Pakistan
Caroline Michaela Kistorp
Copenhagen University Hospital - Herlev and Gentofte, Copenhagen, Denmark; Copenhagen... and other collaborators

Recruiting

Prospective, Longitudinal Study on FItness DOping in DenmarK (FIDO-DK/RH)

Infertility | Mental Health Issue | Fitness | Cardiovascular Complication | Anabolic Steroid Overdose | Illicit Drug Use

Denmark
Mansoura University

Completed

Aromatase Inhibitors or GnRH-a for Uterine Adenomyosis

the Efficacy of Aromatase Inhibitor vs. Gonadotrpins Releasing Hormone Agonists in Treating Premenopausal Women With Uterine Adenomyosis

Egypt
West China Second University Hospital

Recruiting

Cardiac Magnetic Resonance Monitoring of Immune Checkpoint Inhibitor-related Cardiotoxicity

Immune Checkpoint Inhibitors, Cardiotoxicity

China
Vigonvita Life Sciences

Completed

A Study of the Hemodynamic Interactions of TPN171H Tablets & Alcohol in Healthy Male Subjects

Erectile Dysfunction | Alcohol | Phosphodiesterase Inhibitor

China
Beth Israel Deaconess Medical Center

Completed

Evaluation of Ubiquinol on Mitochondrial Oxidative Capacity in Statin Patients Using 31PMRS

Hypercholesterolemia | Myopathy | HMG COA Reductase Inhibitor Adverse Reaction

United States
Istituto Clinico Humanitas

Recruiting

Effect of Action Observation and Motor Imagery on Arthrogenic Muscle Inhibition of the Quadriceps in Patients With End-stage Knee Gonarthrosis.

Knee Osteoarthritis | Arthrogenic Muscle Inhibitions

Italy
Mansoura University

Active, not recruiting

Cardio Renal Effects of SGLT2 Inhibitors Among Lupus Nephritis Patients

Lupus Nephritis | SLE | SGLT2 Inhibitors

Egypt
Mansoura University

Active, not recruiting

SGLT2 Inhibitors Between Reno Protective Effects and Impact on Bone and Mineral Disease Among Lupus Nephritis Patients

Lupus Nephritis | BMD | SGLT2 INHIBITORS

Egypt

Clinical Trials on Steroid Synthesis Inhibitors

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