Clinical Trials on Subjects With Impaired Renal Function and Healthy Subjects

Total 486 results

Jiangsu HengRui Medicine Co., Ltd.

Unknown

A Study to Evaluate the Pharmacokinetics of Apatinib in Subjects With Impaired Renal Function

Subjects With Impaired Renal Function and Healthy Subjects
Shanghai Vinnerna Biosciences Co., Ltd.
Sponsor GmbH

Completed

A Study in Subjects With Liver Function Injury and Subjects With Normal Liver Function

Subjects With Liver Function Injury | Normal Liver Function Subject

China
Pfizer's Upjohn has merged with Mylan to form Viatris...

Terminated

An Open Label Pharmacokinetic Study Of Gabapentin In Japanese Subjects With Renal Impairment Including Hemodialysis

PK Properties Of Gabapentin In Subjects With Impaired Renal Function

Japan
Rempex Pharmaceuticals (a wholly owned subsidiary...

Completed

The Safety and Pharmacokinetics of Carbavance™ (RPX2014/RPX7009) in Subjects With Renal Insufficiency

Subjects With Varying Degrees of Renal Insufficiency and | Subjects With Normal Renal Function

United States
Medical University of Vienna

Completed

Effect of Retaron® on Oxygen Induced Retinal Vasoconstriction in LPS Induced Inflammatory Model in Humans

Healthy Subjects | Imparied Retinal Vascular Reactivity

Austria
Yuhan Corporation

Recruiting

A Multiple Ascending Dose, Phase 1b Study of YH35324 in Atopic Healthy Subjects or Subjects With Mild Allergic Diseases

Atopic Healthy Subjects | Adult Subjects With Mild Allergic Diseases

Korea, Republic of
Yuhan Corporation

Completed

A FIH Study of YH35324 in Atopic Healthy Subjects or Subjects With Mild Allergic Diseases

Atopic Healthy Subjects | Adult Subjects With Mild Allergic Diseases

Korea, Republic of
Trisakti University
Indonesia University; Duke-NUS Graduate Medical School; BioGaia AB

Active, not recruiting

The Effect of Probiotic Lactobacillus Reuteri Prodentis Consumption on Gingival Crevicular Fluid Inflammatory Response and Metagenomic Profiles of Oral Microbiome in Orthodontic Patients.

Healthy Subjects With Fixed Orthodontics

Indonesia
National Taiwan University Hospital

Unknown

Investigation of Pulse Waves, Channel Entries, and Food Attributes in Healthy Subjects With Different Constitutions

Healthy Subjects With Different Constitutions

Taiwan
Astellas Pharma Inc

Completed

Pharmacokinetics Study in Patients With Impaired Renal Function and Subjects With Normal Renal Function

Patients With Impaired Renal Function

Japan
Astellas Pharma Inc

Completed

ASP8825 - Pharmacokinetics Study in Patients With Impaired Renal Function and Haemodialysis

Patients With Impaired Renal Function and Haemodialysis

Japan
Shanghai Vinnerna Biosciences Co., Ltd.
Sponsor GmbH

Completed

A Study in Subjects With Renal Impairment Compared to Subjects With Normal Renal Function

Healthy Subjects | Subjects With Renal Impairment

China
Topcon Medical Systems, Inc.

Completed

Retinal Fundus Camera Evaluation

Normal Healthy Subjects With no Known Ocular Diseases

United States
Pfizer

Completed

A Phase 1 Study To Characterize The Safety, Tolerability, PK And PK Of Repeat Doses Of PF-06648671 In Healthy Adults And Healthy Elderly Subjects

Healthy Adult Subjects and Healthy Elderly Subjects

Belgium
Genta Incorporated

Completed

Pharmacokinetic Study of Genasense in Subjects With Normal Renal Function, Mildly Impaired Renal Function, and Moderately Impaired Renal Function

Normal Renal Function | Mildly Impaired Renal Function | Moderately Impaired Renal Function

United States
Novartis Pharmaceuticals

Terminated

An Open-label, Dose Escalation Multi-center Study in Patients With Advanced Cancer to Determine the Infusion Rate Effect of ASA 404 With Paclitaxel Plus Carboplatin Regimen or Docetaxel on the Pharmacokietics of Free and Total ASA404

Metastatic Cancer With Impaired Renal Function | Metastatic Cancer With Normal Renal Function

Belgium
Chung Shan Medical University

Not yet recruiting

Pharmacokinetic Effect of AstraGin on Whey Protein Absorption and Muscle Function in Healthy Subjects

Pharmacokinetic Effect of AstraGin on Whey Protein Absorption and Muscle Function in Healthy Subjects

Taiwan
Coloplast A/S

Completed

Safety and Performance of New 2-piece Ostomy Product Concept Compared With SenSura Click in Subjects With Ileostomy

Subjects With an Ileostomy

Denmark
AstraZeneca

Completed

A Study to Assess Safety and Tolerability as Well as Absorption and Excretion of TC-5214 in Medically Stable Elderly Subjects

Elderly Subjects 65 Years and Older, Healthy or With a Stable Disease and Treatment.

Sweden
USWM, LLC (dba US WorldMeds)
National Institute on Drug Abuse (NIDA)

Completed

Single-dose Pharmacokinetics and Safety of Oral Lofexidine in Renally-Impaired Subjects

Renally Impaired Subjects

United States
Stealth BioTherapeutics Inc.

Completed

A Phase 1 Study Investigating the Safety and Pharmacokinetics of Repeat-dose Intravenous Infusion of MTP-131 in Subjects With Impaired Renal Function

Normal and Impaired Renal Function

United States
Exelixis

Completed

A Single-Dose Study to Assess the Pharmacokinetics of Cabozantinib (XL184) Capsules in Subjects With Impaired Renal Function

Healthy | Renal Impairment

United States
UCB Pharma
Parexel

Completed

Pharmacokinetic (PK) Study in Japanese Non-epileptic Renal Impaired Patients

Healthy Subjects | Renal Impairments

Japan
MedDay Pharmaceuticals SA
Eurofins Optimed

Terminated

RI Study to Assess and Compare the Pharmacokinetic Parameters of MD1003 in Renal Impaired Patients and Healthy Subjects

Healthy Volunteers | Impaired Renal Function

France, Hungary
Idorsia Pharmaceuticals Ltd.

Completed

A Study to Evaluate ACT-132577 in Healthy Subjects and in People With Severe Kidney Disease

Healthy Subjects | Severe Renal Impairment

Czechia
UCB Biopharma S.P.R.L.

Completed

A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of UCB0942 in Healthy Japanese and Caucasian Subjects

Healthy Japanese and Caucasian Subjects

United Kingdom
Medtronic - MITG

Completed

Pulse Oximetry_Performance Testing- PCBA-1 (Printed Circuit Board Assembly) NEO/PEDS

Subjects With an Existing Intra-arterial Line

United States
University of Sao Paulo General Hospital

Completed

Effects of THW and rhTSH in Glomerular Filtration Rate During RIT

Other Impaired Renal Function Disorder

Brazil
Topcon Medical Systems, Inc.

Completed

Clinical Study of the Optic Disc Parameters

Normal Healthy Subjects With No Known Ocular Diseases | Glaucomatous Eyes | Eyes With Retinal Diseases

United States
Topcon Medical Systems, Inc.

Completed

Maestro Agreement and Precision Study II

Normal Healthy Subjects With No Known Ocular Diseases | Glaucomatous Eyes | Eyes With Retinal Diseases

United States
Bioniz Therapeutics
Celerion

Completed

A Multiple-Dose Study of Intravenous BNZ132-1-40 in Healthy Adult Subjects

Safety and Tolerability in Healthy Subjects

United States
Astellas Pharma Inc

Completed

To Evaluate Whether Acetyl Salicylic Acid (Aspirin) and Darexaban (YM150) Interact in Their Effects

Healthy Subjects | Pharmacodynamic and Pharmacokinetic Interaction

France
Buddhist Tzu Chi General Hospital

Completed

Jing Si Herbal Tea in the Treatment of Dyspeptic Symptoms

Functional Gastrointestinal Disorders | Healthy Subjects

Taiwan
Allergan

Completed

Study of Ulipristal Acetate in Female Patients With Moderately or Severely Impaired Renal Function, Compared With Matched Healthy Female Subjects

Renal Function

United States
Yiling Pharmaceutical Inc.

Completed

A Phase I Pharmacokinetics Study for KT07 Capsule

Pharmacokinetics | Healthy Adult Subjects | Safety and Tolerability

United States
University Hospital Tuebingen
Institute of Ophthalmic Research Tuebingen; Institute for Clinical Epidemiology...

Unknown

Metabolites of Tear Fluid (Metabol-T)

Healthy Subjects

Germany
Astellas Pharma Europe B.V.
FibroGen

Completed

A Phase 1 Study of Roxadustat in Subjects With Different Degrees of Renal Function

Impaired Renal Function | Normal Renal Function

Germany, United Kingdom
Celgene

Completed

A Phase 1 Open-Label Study to Evaluate the Metabolism and Excretion of CC-223 and the Effect of Food on the Pharmacokinetics of CC-223 in Healthy Male Adult Subjects (AME/FE)

Safety and Pharmacokinetics in Healthy Volunteer Subjects

United States
AstraZeneca

Completed

The Purpose of the Study is to Compare Two Fixed Dose Combination Tablets of Dapagliflozin/Metformin XR in Healthy Subjects Under Fasting and Fed Conditions

Healthy Subjects in Fasted and Fed State

Brazil
Astellas Pharma Inc

Completed

To Evaluate if Multiple Doses of Rifampicin Change the Blood Concentration of YM150 (Darexaban)

Healthy Subjects | Pharmacokinetics of Darexaban and Metabolites

France
Asan Medical Center

Recruiting

Phase II Study of Neoadjuvant Immune Checkpoint Inhibitor in Patients With Resectable Gastrointestinal Cancers (NeoChance)

Subjects With Resectable and Localized Gastric Cancer | Subjects With Resectable Esophageal Cancer or Liver Cancer | Subjects With Resectable Liver Cancer

Korea, Republic of
Intermountain Health Care, Inc.

Recruiting

Precision Genomics Medicine Biobank (PRECISE)

Any Disease Condition and Reportedly-healthy Subjects

United States
Novartis Pharmaceuticals

Completed

Evaluation of Renal Function Impairment on the Pharmacokinetics of LEE011

Impaired Renal Function | Normal Renal Function

United States, Germany, Bulgaria, Czechia
Central Hospital, Nancy, France

Recruiting

Optimization of the Acquisition Sequence to Improve the Quality and Comfort of Magnetic Resonance Imaging Exam (AIMANT)

Healthy Subjects | Patient Performing an MRI Examination

France
Astellas Pharma Inc

Completed

To Evaluate if Multiple Doses of Ketoconazole Change the Blood Concentration of YM150 (Darexaban)

Healthy Subjects | Pharmacokinetics of Darexaban and Metabolites

France
Bio-innova Co., Ltd

Not yet recruiting

Sitagliptin and Metformin Hydrochloride Tablets 50 mg/500 mg Relative to Originator

Healthy Subjects
Torrent Pharmaceuticals Limited

Completed

Bioequivalence Study of Torrent Pharmaceuticals Ltd.'s Olmesartan Medoxomil Tablets Under Fed Conditions

Healthy Subjects
Centre Hospitalier St Anne
Fondation pour la Recherche Médicale; Fondation Fyssen; Comité pour la Recherche... and other collaborators

Unknown

Cognitive Biases Under Ketamine (KETABI)

Healthy Subjects

France
Pfizer

Completed

A Multiple Oral Doses Study Of PF-06427878 In Healthy Adult Subjects

Healthy Subjects

Belgium
Eisai Limited

Completed

Pharmacokinetics and Food Effect of Single Oral Dose of E7050 in Healthy Volunteers

Healthy Subjects

Netherlands

Clinical Trials on Subjects With Impaired Renal Function and Healthy Subjects

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Sri Lanka

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations