Clinical Trials on Substance Withdrawal Syndrome

Total 41881 results

Yale University
National Institute on Drug Abuse (NIDA)

Completed

Effects of Transcranial Direct Current Stimulation on Tobacco Withdrawal Symptoms (tDCSsmokers)

Nicotine Withdrawal | Tobacco Abstinence

United States
Spark Biomedical, Inc.
Medical University of South Carolina; University of Texas Southwestern Medical...

Recruiting

Neurostimulation to Improve NOWS Outcomes (SPROUT)

Neonatal Abstinence Syndrome | Neonatal Opioid Withdrawal Syndrome

United States
Thomas Jefferson University
Chiesi Farmaceutici S.p.A.

Completed

Buprenorphine Pharmacometric Open Label Research Study of Drug Exposure (B-PHORE)

Neonatal Abstinence Syndrome | Neonatal Opiate Withdrawal Syndrome

United States
Pediatrix

Completed

Comparison of Buprenorphine to Morphine in Treatment of Neonatal Abstinence Syndrome (NAS)

Neonatal Abstinence Syndrome | Neonatal Withdrawal Syndrome

United States
Jubilee Mission Medical College and Research Institute
INCRE fellowship from DBT, govt of India

Completed

Hyperbaric Oxygenation in Treatment of Alcohol Dependence Syndrome

Alcohol Withdrawal Symptoms | Delirium Tremens (DTs)
USWM, LLC (dba US WorldMeds)

Suspended

Randomized, Double-Blind, Placebo-Controlled Pilot Study on the Safety and Effectiveness of LUCEMYRA During an Opioid Taper in Treatment of Withdrawal (TAPER)

Opioid Withdrawal (Disorder)

United States
Rigshospitalet, Denmark

Not yet recruiting

Treatment of Withdrawal Symptoms With NADA Acupuncture in Chronic Pain Patients

Chronic Pain | Opiate Withdrawal Syndrome

Denmark
University of California, Berkeley
University of California, San Francisco

Completed

The Potentially Addictive Properties of Soda: A Feasibility Study

Withdrawal Symptoms

United States
Cristina Martínez Martínez
Hospital Clinic of Barcelona; Fundació Institut de Recerca de l'Hospital de... and other collaborators

Not yet recruiting

Characterization of the Pattern of Consumption and Withdrawal Syndrome From Dual Cannabis and Tobacco Use (DuCATA_GAMCaT)

Tobacco Use | Cannabis Dependence | Substance Abuse | Withdrawal Syndrome
Tel-Aviv Sourasky Medical Center

Unknown

Treatment of Marijuana Withdrawal Syndrome Using Escitalopram and Cognitive-Behavior Therapy

Marijuana Dependence

Israel
Attikon Hospital

Completed

Postoperative Headache in Elective Surgery Patients

Drug Withdrawal Headache
University of Pittsburgh
Indiana University of Pennsylvania

Completed

The Effect of Self-Forgiveness on Self-Stigma in Addiction.

Substance Use Disorders | Benzodiazepine Dependence | Alcohol Use Disorder | Substance Abuse | Opioid-use Disorder | Cocaine Use Disorder | Alcohol Abuse | Opiate Dependence | Alcohol Withdrawal | Benzodiazepine Abuse | Cocaine Abuse | Heroin Abuse | Cocaine Withdrawal | Opiate Withdrawal Syndrome | Heroin Overdoses | Heroin...

United States
USWM, LLC (dba US WorldMeds)
National Institute on Drug Abuse (NIDA)

Completed

Open-Label, Safety Study of Lofexidine (NU LEAF)

Opioid Withdrawal

United States
Centre for Addiction and Mental Health

Terminated

Abuse Liability of Pregabalin and Its Effects on Benzodiazepine Withdrawal Symptoms

Substance-Related Disorders

Canada
Lallemand Health Solutions
MedQualis; Q & T Research

Completed

Efficacy of 2 Probiotics During Nicotine Replacement Therapy on Withdrawal Symptoms Associated With Smoking Cessation

Smoking Cessation

Canada
Hospital Clinic of Barcelona
Fondo de Investigacion Sanitaria; European Commission; TcLand Expression S.A.

Unknown

Assessment Of the Safety and Benefit of Prospective Immunosuppressive Drug Withdrawal in Liver Transplantation and Prediction of Operational Tolerance

Liver Transplantation

Spain
University of Pennsylvania

Completed

Combining Pregabalin (LYRICA®) With Lofexidine (LUCEMYRATM) to Treat OPIOID Withdrawal (PGB-LOF)

Opioid Withdrawal

United States
Elite Laboratories, Inc

Completed

A Study to Evaluate Withdrawal Effects Following Dosing of Oxycodone/Naltrexone in Methadone-Maintained Subjects

Withdrawal Symptoms

United States
Wilkes University

Completed

AduLt iatrogEnic withdRawal sTudy in the ICU (ALERT-ICU)

Iatrogenic Disease | Withdrawal Syndrome

United States
Yale University

Recruiting

Prazosin for Alcohol Use Disorder With Withdrawal Symptoms

Alcohol Withdrawal

United States
Johns Hopkins University
National Institute on Drug Abuse (NIDA); University of Florida

Recruiting

Direct Observation Study of Kratom Product Effects Among Regular Consumers

Kratom Withdrawal Symptoms | Kratom Pharmacokinetics | Kratom Pharmacodynamics

United States
M.D. Anderson Cancer Center
National Institutes of Health (NIH)

Completed

Genetic Differences in Limbic Activation Associated With Nicotine Withdrawal

Smoking

United States
Johns Hopkins University

Completed

Buspirone for Opioid Tapering

Opioid-Related Disorders | Pain, Chronic | Dependency (Psychology) | Opiate Withdrawal Syndrome

United States
Inha University Hospital
National Research Foundation of Korea

Terminated

Effects of Auricular Acupressure and Group Counseling on Smoking Cessation Tobacco Withdrawal Symptoms

Smoking

Korea, Republic of
Gauda, Estelle B., M.D.
Johns Hopkins University; Johns Hopkins All Children's Hospital

Unknown

Sublingual Buprenorphine Treatment for Neonatal Abstinence Syndrome - Pilot Study

Withdrawal | Drug; Withdrawal Symptoms, Neonatal | Fetus and Newborn Affected by Other Maternal Medication

United States
Buddhist Tzu Chi General Hospital

Recruiting

The Effect of Honey on Lessening the Withdrawal Symptoms

Smoking Cessation | Withdrawal Symptoms

Taiwan
BrightView LLC
Innovative Health Solutions

Terminated

BRIDGE Device for Treatment of Opioid Withdrawal

Pain | Craving | Opioid Withdrawal

United States
University of Vermont
National Institute on Drug Abuse (NIDA); Johns Hopkins University; University... and other collaborators

Completed

Maternal Opioid Treatment: Human Experimental Research - Data Yield Appropriate Decisions (MOTHER DYAD)

Opioid-use Disorder | Neonatal Abstinence Syndrome | Opioid Withdrawal | Neonatal Opioid Withdrawal Syndrome

United States
Duke University
National Institute on Drug Abuse (NIDA); National Institutes of Health (NIH); Food and Drug Administration (FDA)

Terminated

Nicotine Withdrawal and Reward Processing: Connecting Neurobiology to Real-world Behavior (NicWith)

Cigarette Smoking | Nicotine Withdrawal

United States
Stanford University
National Institute on Drug Abuse (NIDA)

Completed

5HT3 Antagonists to Treat Opioid Withdrawal and to Prevent the Progression of Physical Dependence

Opioid Withdrawal | Physical Dependence

United States
Meir Medical Center

Completed

Methadone vs. Transdermal Fentanyl for Opioid Withdrawal Syndrome

Delirium in the Intensive Care Unit

Israel
CAMC Health System

Unknown

Assessment of Valproate on Ethanol Withdrawal (PAVE)

Alcohol Dependence | Trauma | Alcohol Use Disorder | Alcohol Withdrawal Syndrome | Heavy Drinking

United States
King Abdullah International Medical Research Center

Recruiting

Prospective, Randomized, Open Label Controlled Trial To Evaluate The Safety And Efficacy Of Dexmedetomidine Use Beyond 24 Hours Compared With Midazolam In Children Admitted To Pediatric Intensive Care Unit at King Abdullah Specialist Children Hospital- Ministry of National Guard Health Affairs. (PROMISE)

Dexmedetomidine | Withdrawal Symptoms | Midazolam | Failure of Extubation

Saudi Arabia
BioXcel Therapeutics Inc
Cognitive Research Corporation

Completed

Dexmedetomidine in the Treatment of Symptoms Of Acute Opioid Withdrawal (RELEASE)

Opioid Withdrawal

United States
University of Minnesota
National Institute on Drug Abuse (NIDA)

Completed

Medicinal Nicotine for Preventing Stress Induced Craving and Withdrawal Symptoms

Tobacco Use Disorder

United States
T. John Winhusen, PhD
National Institute on Drug Abuse (NIDA); The Emmes Company, LLC

Recruiting

Medication Treatment for Opioid Use Disorder in Expectant Mothers: Infant Neurodevelopmental Outcomes Sub-study (MOMs-INO)

Pregnancy Related | Opioid-Related Disorders | Substance Abuse | Drug Abuse | Drug Addiction | Neonatal Abstinence Syndrome | Neonatal Opiate Withdrawal Syndrome | Drug Abuse in Pregnancy

United States
T. John Winhusen, PhD
National Institute on Drug Abuse (NIDA); The Emmes Company, LLC

Active, not recruiting

Medication Treatment for Opioid Use Disorder in Expectant Mothers (MOMs)

Pregnancy Related | Opioid-Related Disorders | Substance Abuse | Drug Abuse | Drug Addiction | Neonatal Abstinence Syndrome | Drug Abuse in Pregnancy | Neonatal Opioid Withdrawal Syndrome

United States
Oslo University Hospital

Completed

Tapering of Analgosedation and Occurrence of Withdrawal Syndrome in Paediatric Intensive Care Treatment (ASWISPIC)

Child | Critical Care | Drug Withdrawal Symptoms

Norway
T. John Winhusen, PhD
National Institute on Drug Abuse (NIDA); The Emmes Company, LLC

Active, not recruiting

Medication Treatment for Opioid Use Disorder in Expectant Mothers: Conceptual Model Assessments Sub-study (MOMs-CMA)

Pregnancy Related | Opioid-Related Disorders | Substance Abuse | Drug Abuse | Drug Addiction | Neonatal Abstinence Syndrome | Drug Abuse in Pregnancy | Neonatal Opioid Withdrawal Syndrome

United States
Mayo Clinic

Recruiting

Glucocorticoid Withdrawal Syndrome in Patients With Treated Cushing Syndrome

Cushing Syndrome

United States
Melva Louisa

Completed

The Efficacy of N-acetylcysteine Versus Placebo for the Treatment of Metamphetamine Withdrawal Symptoms

Methamphetamine Dependence in Remission

Indonesia
Dalhousie University
Holistic Health Research Foundation of Canada

Completed

Therapeutic Massage to Manage Withdrawal Related Anxiety

Anxiety | Substance Withdrawal Syndrome | Drug Withdrawal Symptoms

Canada
Anders Fink-Jensen, MD, DMSci

Unknown

Does a Ketogenic Dietary Supplement Reduce Alcohol Withdrawal Symptoms in Humans? (KME)

Alcohol Use Disorder | Ketosis | Alcohol Withdrawal

Denmark
Inha University Hospital
National Research Foundation of Korea

Recruiting

Effects of Positive Psychological Group Psychotherapy and Auricular Acupressure on Withdrawal Symptoms

Gambling

Korea, Republic of
University of Pennsylvania

Terminated

SPECT Imaging of DAT Genotype (DDAT)

Nicotine Withdrawal

United States
OSF Healthcare System

Unknown

Phenobarbital vs Ativan for Alcohol Withdrawal in the Intensive Care Unit (PARTI)

Alcohol Withdrawal | Alcohol Withdrawal Delirium

United States
Instituto Nacional de Psiquiatría Dr. Ramón de...

Completed

Clinical Studies on the Therapeutic Effects of Mirtazapine on Drug-craving in Cocaine Addicts. (MADC)

Drug-withdrawal. | Drug Abuse | Drug-induced Depressive State | AOD Craving | AODR Depressive State

Mexico
National Defense Medical Center, Taiwan

Recruiting

Effects of HRV Biofeedback on Autonomic Function and Nicotine Withdrawal Symptoms and Dependence in Smoking Cessation Adults

Heart Rate Variability, Biofeedback, Nicotine Dependence, Nicotine Withdrawal, Anxiety, Depression, Insomnia

Taiwan
University of Oklahoma
National Institute on Drug Abuse (NIDA); Oklahoma State University

Completed

Nicotine Withdrawal and Reward Processing (NicWith)

Nicotine Dependence | Cigarette Smoking | Nicotine Withdrawal

United States
Arizona State University
National Institute on Drug Abuse (NIDA); Pfizer; University of Nevada, Reno; Los...

Completed

Varenicline OTC Trial on Efficacy and Safety (VOTC)

Smoking Cessation | Withdrawal Symptoms | Tobacco Dependence

United States

Clinical Trials on Substance Withdrawal Syndrome

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