Clinical Trials on Substance Dependence

Total 9171 results

Yale University

Terminated

Glucocorticoid Antagonist Treatment for Tobacco Use Disorder

Nicotine Dependence

United States
New York State Psychiatric Institute
National Institute on Drug Abuse (NIDA)

Terminated

The Effect of Brief Potent Glutamatergic Modulation on Cocaine Dependence

Cocaine Dependence

United States
New York State Psychiatric Institute

Completed

Glutamatergic Modulation of Cocaine-related Deficits

Cocaine Dependence

United States
New York State Psychiatric Institute
National Institute on Drug Abuse (NIDA)

Completed

Open-Label Pilot Study of Lisdexamfetamine for Cocaine Dependence (Vyvance)

Cocaine Dependence

United States
New York State Psychiatric Institute
National Institute on Drug Abuse (NIDA)

Completed

Multicenter Trial of Combined Pharmacotherapy to Treat Cocaine Dependence (TACT2)

Cocaine Dependence

United States
University of Virginia

Completed

A Mindfulness Based Application for Smoking Cessation (MBSC)

Nicotine Dependence

United States
Medical University of South Carolina

Completed

Impact of Varenicline on Blood-Oxygen-Level Dependent (BOLD) Functional Magnetic Resonance Imaging (fMRI) Activation on Smokers (GRAND)

Nicotine Dependence

United States
University of California, San Francisco
National Institute on Drug Abuse (NIDA)

Completed

Tobacco Intervention in Buprenorphine Treatment (IBIS)

Tobacco Dependence

United States
Centre for Addiction and Mental Health

Completed

Smoking While on Transdermal Nicotine Replacement Therapy: Effects on Craving and Cessation

Nicotine Dependence

Canada
Biotie Therapies Inc.
National Institute on Drug Abuse (NIDA)

Completed

Study of Safety and Potential Efficacy of SYN117 in Cocaine Dependent Volunteers

Cocaine Dependence

United States
National Institute on Drug Abuse (NIDA)

Completed

A Multi-Modal Investigation of the Smoking Cessation Medication Varenicline: Dopaminergic Modulation of Reward Processing and Cognitive Control

Tobacco Use Disorder | Nicotine Dependence

United States
National Institute on Drug Abuse (NIDA)

Completed

Nicotinic Modulation of the Default Network of Resting Brain Function

Nicotine Dependence

United States
Medical University of South Carolina
National Institute on Drug Abuse (NIDA)

Completed

Achieving Cannabis Cessation-Evaluating N-Acetylcysteine Treatment (ACCENT)

Cannabis Dependence

United States
Medical University of South Carolina

Completed

Gender Differences in Response to Cues in Cocaine Dependence

Cocaine Dependence

United States
The University of Texas Health Science Center,...
National Institute on Drug Abuse (NIDA)

Completed

Carbidopa/Levodopa Combined With Behavioral Therapy for the Treatment of Cocaine Dependence

Cocaine Dependence

United States
National Institute on Drug Abuse (NIDA)

Completed

Nicotine Reinforcement and Smoking-Cue Reactivity: Association With Genetic Polymorphisms

Nicotine Dependence

United States
University of Pennsylvania
National Institute on Drug Abuse (NIDA); Society of Alcoholism and other Addictions

Completed

Extended Release Naltrexone for Treating Amphetamine Dependence in Iceland

Amphetamine Dependence

Iceland
University of Rochester
National Cancer Institute (NCI); National Library of Medicine (NLM)

Completed

Web Assisted Tobacco Intervention With Community Colleges (WATI)

Tobacco Dependence

United States
Duke University
National Institute on Drug Abuse (NIDA)

Completed

Mechanistic Evaluations of Pre-Cessation Therapies for Smoking Cessation (ConNicBrain)

Nicotine Dependence

United States
National Institute on Drug Abuse (NIDA)

Completed

Breath Carbon Monoxide and Cotinine as Biomarkers to Distinguish Smokers From Nonsmokers

Nicotine Dependence

United States
Yale University
VA Office of Research and Development

Withdrawn

Atomoxetine's Effects On Nicotine Response And Stress Response In Smokers

Nicotine Dependence

United States
New York State Psychiatric Institute
National Institute on Drug Abuse (NIDA)

Completed

Effect of Baclofen on Marijuana Withdrawal and Relapse

Marijuana Dependence

United States
Massachusetts General Hospital
Janssen, LP

Completed

Study of the Effects of Risperdal Consta on Brain Reward Circuitry Function, Craving and Cocaine Use in Active Cocaine Dependence

Cocaine Dependence

United States
Centre for Addiction and Mental Health

Completed

Initial Screening of Gemfibrozil as a Novel Treatment for Tobacco Addiction

Nicotine Dependence

Canada
The Queen Elizabeth Hospital
University of Adelaide

Completed

Improving Health for Aboriginal People Through Tobacco Related Research

Tobacco Dependence

Australia
Temple University
National Cancer Institute (NCI)

Completed

Counseling to Reduce Children's SHS Exposure: A Trial With Maternal Smokers

Nicotine Dependence

United States
University of Electronic Science and Technology...
German Research Foundation; University Hospital, Bonn

Completed

Social and Emotional Brain Function in Cannabis Users

Cannabis Dependence

Germany
National Institute on Drug Abuse (NIDA)
University of Minnesota

Completed

Role of Metabolites in Nicotine Dependence (1) - 1

Tobacco Use Disorder

United States
National Institute on Drug Abuse (NIDA)

Completed

A Survey on Consumer Use of Over-the-Counter (OTC) Nicotine Patches

Tobacco Use Disorder | Nicotine Dependence

United States
Yale University
National Institute on Drug Abuse (NIDA); National Institutes of Health (NIH)

Completed

Enhancing a High School Based Smoking Cessation Program

Nicotine Dependence

United States
New York State Psychiatric Institute
Novel Cocaine Pharmacotherapies

Terminated

Effects of Vigabatrin on Cocaine Self-Administration

Cocaine Dependence

United States
University of Pennsylvania

Withdrawn

A Study of Baclofen ER (CURE)

Cocaine Dependence

United States
Yale University

Completed

Modafinil, Sleep Architecture and Cocaine Relapse

Cocaine Dependence

United States
Centre for Addiction and Mental Health
Pfizer; Ontario Lung Association

Completed

The Effect of Varenicline on D2/D3 Receptor Binding in Smokers

Nicotine Dependence

Canada
Medical University of South Carolina

Completed

Effect of Oxytocin on Stress in Marijuana Users

Marijuana Dependence

United States
University of Wisconsin, Madison
National Institute on Drug Abuse (NIDA)

Completed

Trial on the Effectiveness of Mindfulness Training for Smokers (MTS)

Nicotine Dependence

United States
Centre for Addiction and Mental Health
Ontario Lung Association

Terminated

Prazosin for Smoking Cessation

Nicotine Dependence

Canada
Southern Illinois University Carbondale
National Institute on Drug Abuse (NIDA)

Completed

Nicotine Patch for Marijuana Withdrawal (NMW)

Marijuana Dependence

United States
Duke University

Completed

Extinction Based Treatment for Nicotine Dependence (Extinction01)

Nicotine Dependence

United States
Butler Hospital
National Institute on Drug Abuse (NIDA)

Completed

Behavioral Exercise Intervention for Smoking Cessation

Nicotine Dependence
Virginia Commonwealth University
National Institute on Drug Abuse (NIDA)

Completed

Behavioral Incentives to Increase Exercise in Cocaine Dependent Women

Cocaine Dependence

United States
Assistance Publique - Hôpitaux de Paris
National Research Agency, France

Withdrawn

A PET Exploration of the Mechanism of Action of Dopamine Beta-hydroxylase Inhibition in Cocaine Addicts (RAPID)

Cocaine Dependence

France
University of Pennsylvania

Completed

Assessment of High Dose Transdermal Nicotine for Fast Metabolizers of Nicotine (HDP)

Nicotine Dependence

United States
New York State Psychiatric Institute
National Institute on Drug Abuse (NIDA)

Completed

Progesterone Treatment for Cocaine-dependent Women: A Pilot Study (PROG)

Cocaine Dependence

United States
University of Stellenbosch
QuitSupport

Completed

Varenicline in Combination With Nicotine Replacement Therapy for Smoking Cessation

Tobacco Dependence

South Africa
The Miriam Hospital
Live Inspired, LLC

Completed

Examining a Text Message Intervention for Smoking Cessation

Tobacco Use Disorder | Nicotine Dependence

United States
Midwest Biomedical Research Foundation

Withdrawn

Tacrine Effects on Cocaine Self-Administration and Pharmacokinetics

Cocaine Dependence

United States
H. Lee Moffitt Cancer Center and Research Institute
Pfizer

Completed

Varenicline Effects on Cue Reactivity and Smoking Reward/Reinforcement

Tobacco Dependence

United States
University of Pennsylvania
National Institute on Drug Abuse (NIDA)

Completed

Effects of Naltrexone on Nicotine Reinforcement

Tobacco Dependence

United States
Johns Hopkins University
National Institute on Drug Abuse (NIDA); Food and Drug Administration (FDA)

Completed

The Effect of Marijuana and Prescription Medications in Mood, Performance and Sleep

Marijuana Dependence

United States

Clinical Trials on Substance Dependence

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