Clinical Trials on Surgically-Induced Liver Failure

Total 1622 results

Janssen R&D Ireland

Withdrawn

An Efficacy, Safety, Tolerability and Pharmacokinetics Study of 12 Weeks Treatment With Simeprevir and Daclatasvir in Participants With Chronic Hepatitis C Virus Genotype 1b or 4 Infection and Either Severe Renal Impairment or End-stage Renal Disease on Hemodialysis.

Renal Impairment | End-stage Renal Disease

France, Spain
Gilead Sciences

Completed

Sofosbuvir/Velpatasvir in Adults With Chronic Hepatitis C Virus Infection Who Are on Dialysis for End Stage Renal Disease (SOF/VEL ESRD)

Chronic Hepatitis C

Israel, United Kingdom, Australia, Spain, Canada, New Zealand
Medical College of Wisconsin
The Cleveland Clinic

Not yet recruiting

PAtient Similarity for Decision-Making in Prevention of Cardiovascular Toxicity (PACT): A Feasibility Study

Ischemia | Coronary Artery Disease | Heart Failure | Hypertension | Diabetes Mellitus | Cardiomyopathies | Peripheral Artery Disease | Cardiotoxicity

United States
The Rogosin Institute
Outset Medical; CareTaker Medical LLC

Completed

Evaluation of Non-Invasive Continuous vs Intermittent BloodPressure Monitors in Maintenance Dialysis (BP Dialysis)

End Stage Renal Disease | End Stage Renal Disease on Dialysis | Dialysis Hypotension | Dialysis Induced Hypertension

United States
Medical University of Bialystok

Completed

Effect of Home Rehabilitation on State of Patients With PAH, HFREF and IHD

Ischemic Heart Disease | Pulmonary Hypertension | Heart Failure With Reduced Ejection Fraction

Poland
Columbia University
National Institute on Drug Abuse (NIDA); Johns Hopkins University; University... and other collaborators

Recruiting

Project I Test: Implementing HIV Testing in Opioid Treatment Programs

Hepatitis C | HIV/AIDS | Substance Use Disorders | Opioid-use Disorder

United States
Mirum Pharmaceuticals, Inc.

Completed

Safety and Efficacy Study of LUM001 (Maralixibat) With a Drug Withdrawal Period in Participants With Alagille Syndrome (ALGS) (ICONIC)

Alagille Syndrome

France, Belgium, Poland, Australia, Spain, United Kingdom
Liver Institute of Virginia
Merck Sharp & Dohme LLC; Chronic Liver Disease Foundation

Unknown

A Pilot Study to Treat Patients With Chronic Hepatitis C Virus (HCV) Genotype 1 and End-Stage Renal Disease (ESRD)

End Stage Renal Disease | Chronic Hepatitis C

United States
National Taiwan University Hospital

Completed

Interferon Treatment for Patients With Chronic Hepatitis C and End Stage Renal Disease

End Stage Renal Disease | Chronic Hepatitis C

Taiwan
University Tunis El Manar

Completed

BH4 Blood Levels Variations in Pre Eclamptic Women (BH4P)

Acute Renal Failure | Pre Eclampsia | Eclampsia, Antepartum | HELLP Syndrome (HELLP), Unspecified Trimester | Abruptio Placentae; Complicating Pregnancy

Tunisia
University of Pennsylvania
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); Gilead...

Recruiting

A Trial of Transplanting Hepatitis C Kidneys Into Hepatitis C-Negative Kidney Recipients (THINKER-NEXT)

End Stage Renal Disease

United States
The First Affiliated Hospital of Nanchang University

Unknown

Follow-up Study of Complications of Acute Pancreatitis (FSCAP)

Metabolic Diseases | Quality of Life | Respiratory Failure | Pancreatic Neoplasms | Hypertension, Portal | Pancreatitis

China
University Hospital, Bordeaux
Hoffmann-La Roche; Ministry of Health, France

Completed

Treatment of Chronic Hepatitis C With PEG Interferon alfa2a and Ribavirin in HIV-Infected Patients (ROCO2)

HIV Infections | Hepatitis C, Chronic | Treatment Failure

France
University of California, San Diego

Enrolling by invitation

Ventilation and Perfusion in the Respiratory System

Critical Illness | Respiratory Failure | Pulmonary Disease | Ventilator-Induced Lung Injury | Respiratory Distress Syndrome, Adult

United States
AHS Cancer Control Alberta
Cross Cancer Institute

Completed

A Prospective Study of Acute Cardiovascular Effects of First-line Sunitinib in Metastatic Renal Cell Carcinoma Patients (SUnitinib Prospective CardiovasculaR Effect) (SUPER)

Heart Failure | Renal Cell Carcinoma | Hypertension | Cardiotoxicity

Canada
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Completed

Zinc Supplements in Lowering Cadmium Levels in Smokers

Kidney Cancer | Cervical Cancer | Leukemia | Head and Neck Cancer | Gastric Cancer | Pancreatic Cancer | Esophageal Cancer | Tobacco Use Disorder | Lung Cancer | Bladder Cancer | Liver Cancer

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Motivational Counseling in Preventing Smoking Relapse After Pregnancy in Pregnant Women Who Quit Smoking During Pregnancy

Kidney Cancer | Cervical Cancer | Leukemia | Head and Neck Cancer | Gastric Cancer | Pancreatic Cancer | Esophageal Cancer | Tobacco Use Disorder | Lung Cancer | Bladder Cancer | Liver Cancer

United States
Roswell Park Cancer Institute
National Cancer Institute (NCI)

Completed

Acceptability of Less Harmful Alternatives to Cigarettes

Kidney Cancer | Cervical Cancer | Leukemia | Head and Neck Cancer | Gastric Cancer | Pancreatic Cancer | Esophageal Cancer | Tobacco Use Disorder | Lung Cancer | Bladder Cancer | Liver Cancer

United States
Bark Technology LLP

Recruiting

Evaluation of the Effectiveness and Safety of Vibro-acoustic Pulmonary Therapy (VAPT) in Complex Therapy for Acute Respiratory Failure of Mixed Type I-II Stages in Comparison With Percussion Massage in Cardiac Surgical Patients in the Early Postoperative Period

Cardiac Surgical Patients (CABG,Mammary Coronary Bypass Surgery,Plastic and Replacement of Valves, Atrial Septal Defect,Ventricular Septal Defect)

Kazakhstan
Butler Hospital
National Cancer Institute (NCI)

Completed

Varenicline or Nicotine Patch and Nicotine Gum in Helping Smokers in a Methadone Treatment Program Stop Smoking

Kidney Cancer | Cervical Cancer | Leukemia | Head and Neck Cancer | Gastric Cancer | Pancreatic Cancer | Esophageal Cancer | Tobacco Use Disorder | Lung Cancer | Bladder Cancer | Liver Cancer

United States
Lisa Sanderson Cox, PhD
National Cancer Institute (NCI)

Completed

Health Education Counseling With or Without Bupropion in Helping African Americans Stop Smoking

Kidney Cancer | Cervical Cancer | Leukemia | Head and Neck Cancer | Gastric Cancer | Pancreatic Cancer | Esophageal Cancer | Tobacco Use Disorder | Lung Cancer | Bladder Cancer | Liver Cancer

United States
Roswell Park Cancer Institute

Completed

Bupropion in Helping Adults Stop Smoking

Kidney Cancer | Cervical Cancer | Leukemia | Head and Neck Cancer | Gastric Cancer | Pancreatic Cancer | Esophageal Cancer | Tobacco Use Disorder | Lung Cancer | Bladder Cancer | Liver Cancer

United States
Fox Chase Cancer Center
National Cancer Institute (NCI)

Completed

Counseling and Nicotine Replacement Therapy in Helping Adult Smokers Quit Smoking

Kidney Cancer | Cervical Cancer | Leukemia | Head and Neck Cancer | Gastric Cancer | Pancreatic Cancer | Esophageal Cancer | Tobacco Use Disorder | Lung Cancer | Bladder Cancer | Liver Cancer

United States
G.V. (Sonny) Montgomery VA Medical Center
Merck Sharp & Dohme LLC

Completed

VBMI to Increase Treatment Completion With MK-MK-5172/MK-8742 Among Veterans With Active Substance Use Disorders Genotype 1 Chronic Hepatitis C (VBMI SUD/HCV)

Patient Adherence, Chronic Hepatitis C, Alcohol-related Disorders

United States
Denver Health and Hospital Authority

Completed

Trial of Injected Liposomal Bupivacaine vs Bupivacaine Infusion After Surgical Stabilization of Rib Fractures

Pneumonia | Anesthesia, Local | Drug Effect | Opioid Dependence | Surgical Procedure, Unspecified | Rib Fractures | Local Infiltration | Nerve Pain | Rib Trauma | Pain; Catheter (Other) | Intercostal Rib | Chest Injury Trauma

United States
Haukeland University Hospital
University of Bergen; Helse Stavanger HF; Helse Vest; Forskningsrådet; Folkehelse... and other collaborators

Active, not recruiting

Integrated Treatment of Hepatitis C Virus Infection (INTRO-HCV)

Hepatitis C, Chronic | Opioid Dependence, on Agonist Therapy

Norway
Assiut University

Not yet recruiting

Maternal alpha1 Antitrypsin as a Marker of Intrauterine Growth Restriction in Pre-eclamptic Women

Pre-Eclampsia | Intrauterine Growth Restriction | alpha1 Anti-trypsin
Rhode Island Hospital
National Institute on Drug Abuse (NIDA)

Completed

Brief Intervention for Drug Misuse in the Emergency Department (BIDMED)

HIV Infections | Hepatitis B | Hepatitis C | HIV | Substance Abuse Detection | Brief Intervention

United States
National Institute of Diabetes and Digestive and...
Massachusetts General Hospital; University of Pennsylvania; Yale University; New... and other collaborators

Completed

HOPE Consortium Trial to Reduce Pain and Opioid Use in Hemodialysis (HOPE)

Chronic Pain | End Stage Renal Disease | Opioid Dependence

United States
University of Pennsylvania
Merck Sharp & Dohme LLC

Completed

Transplanting Hepatitis C Kidneys Into Negative Kidney Recipients (THINKER)

End Stage Renal Disease

United States
Duke University
Gilead Sciences

Completed

Hepatitis C Virus(HCV) Heart and Lung Study

Heart Failure | Pulmonary Disease, Chronic Obstructive | Hepatitis C, Chronic | Lung Diseases, Interstitial

United States
AbbVie

Withdrawn

Study of Ombitasvir/Paritaprevir/Ritonavir in Japanese Adults With Genotype 1b Chronic Hepatitis C Virus (HCV) Infection With End Stage Renal Disease (ESRD) on Hemodialysis (HD) (GIFT-R)

Chronic Hepatitis C Virus
Abramson Cancer Center at Penn Medicine
National Heart, Lung, and Blood Institute (NHLBI)

Active, not recruiting

Pilot Study of an NTproBNP Guided Strategy of Cardioprotection (NTproBNP-Guide)

Heart Failure | Lymphoma | Breast Cancer | Cardiomyopathies | Cardiotoxicity | Toxicity Due to Chemotherapy

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Sodium Thiosulfate in Preventing Hearing Loss in Young Patients Receiving Cisplatin for Newly Diagnosed Germ Cell Tumor, Hepatoblastoma, Medulloblastoma, Neuroblastoma, Osteosarcoma, or Other Malignancy

Sarcoma | Ovarian Cancer | Brain Tumor | Ototoxicity | Neuroblastoma | Liver Cancer | Central Nervous System Tumor | Extragonadal Germ Cell Tumor | Childhood Germ Cell Tumor

Canada, United States, Australia
Icare Finland Oy

Unknown

Defining the Operating Parameters for a Rebound-esthesiometer

Corneal Dystrophy | Corneal Degeneration | Corneal Sensation Reduced | Corneal Transplant Failure | Herpetic Keratitis
University of Illinois at Chicago
Merck Sharp & Dohme LLC

Active, not recruiting

Zepatier in Patients With Substance Use

Hepatitis C | Hiv | Substance Use Disorders | Coinfection, HIV

United States
University of California, Los Angeles
California HIV/AIDS Research Program; Friends Research Institute, Inc.; Charles... and other collaborators

Completed

Prevention Support for People Leaving Jail (MEPS)

HIV Infections | Hepatitis C | Substance Use Disorders | Sexually Transmitted Diseases, Bacterial

United States
Chinese University of Hong Kong

Recruiting

Safety and Efficacy of Fecal Microbiota Transplantation

Alcohol Dependence | Multiple Sclerosis | Obesity | Diabetes Mellitus | Hepatic Encephalopathy | Irritable Bowel Syndrome | Constipation | Celiac Disease | Crohn Disease | Ulcerative Colitis | Liver Disease | Idiopathic Thrombocytopenic Purpura | Clostridium Difficile Infection | Alopecia | Autism | Multiple Organ Dysfunction... and other conditions

Hong Kong
Fondazione Policlinico Universitario Agostino Gemelli...

Recruiting

Diet in Twin Pregnancy: the Wellness of Mother and Babies. (FIT)

Diet, Healthy | Gestational Diabetes | Intrahepatic Cholestasis of Pregnancy | Food Habits | Twin Pregnancy, Antepartum Condition or Complication | Gestational Hypertension

Italy
Changhai Hospital

Completed

Serum HBV RNA Value on Chronic Hepatitis B Virus Infection Manage

Chronic HBV Infection | Drug Withdrawal
Johns Hopkins University

Completed

Kidney Transplants in Hepatitis C Negative Recipients With Hepatitis C Viremic Donors

Hepatitis C | End Stage Renal Disease

United States
Massachusetts General Hospital

Completed

QUICKly Eradicate Hepatitis C in Patients Undergoing REnal Transplant With 4 Weeks of Glecaprevir/Pibrentasvir (QUICK-CURE)

Hepatitis C | Kidney Disease, Chronic | Kidney Failure

United States
Silesian Centre for Heart Diseases
Medical Research Agency, Poland

Not yet recruiting

Sacubitril/Valsartan in PriMAry preventIoN of the Cardiotoxicity of Systematic breaST canceR trEAtMent (MAINSTREAM)

Heart Failure | Breast Cancer | Breast Diseases | Cardiotoxicity | Molecular Mechanisms of Pharmacological Action | Angiotensin Receptor Antagonists | Neoplasm, Breast | Cardiac Toxicity | Angiotensin II Type 1 Receptor Blockers | Cancer, Therapy-Related | Antihypertensive Agents | Sacubitril/Valsartan | Cancer...

Poland
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Widefield Fluorescence and Reflectance Imaging Systems and Oral Tissue Samples in Monitoring Participants at Risk for Developing Oral Cancer

Tobacco Use Disorder | Fanconi Anemia | Lichen Planus | Oral Neoplasm | Erythroplakia | Premalignant Lesion | Oral Cavity and Lip Precancerous Condition | Oral Cavity Leukoplakia

United States
New York University
National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Completed

Computer-based Intervention for Alcohol-using HIV/HCV+ Women

Hepatitis C | Human Immunodeficiency Virus | Alcohol Abuse

United States, Russian Federation
Mayo Clinic

Not yet recruiting

A Study of the Effect of a Nurse Navigator Program on High Risk Patients

Heart Failure | Alcoholism | Renal Insufficiency | Pulmonary Disease, Chronic Obstructive | Arthroplasty, Replacement, Knee | Arthroplasty, Replacement, Hip | Body Mass Index | Patient Readmission

United States
April M Young
National Institute on Drug Abuse (NIDA); Emory University; Centers for Disease... and other collaborators

Completed

Kentucky Communities and Researchers Engaging to Halt the Opioid Epidemic (CARE2HOPE)

HIV Infections | Substance Use | Opioid Use | HCV Infection | Sexually Transmitted Infections (Not HIV or Hepatitis) | Overdose, Drug

United States
Progenity, Inc.

Unknown

Collection of Whole Blood Samples for the Evaluation of Preeclampsia (Pre-E) Biomarkers From Pregnant Women

Hypertension | Renal Insufficiency | Thrombocytopenia | Headache | Pre-Eclampsia | Pulmonary Edema | Visual Impairment | Impaired Liver Function | Proteinuria in Pregnancy

United States
Michele Staton
National Institute on Drug Abuse (NIDA)

Completed

Brief Intervention for Rural Women at High Risk for HIV/HCV (WISH)

Hepatitis C | Drug Abuse | Acquired Immune Deficiency Syndrome Virus

United States
University Hospital, Limoges

Recruiting

Acceptability of Simultaneous Screening for Viral Hepatitis B, C and HIV Among Drug Users in Non-conventional Structures (SCANVIR)

Hepatitis C | Hepatitis C Virus Infection, Response to Therapy of | Addiction, Alcohol | Addiction Opiate | Transmission, Intravenous Drug Abuser

France

Clinical Trials on Surgically-Induced Liver Failure

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Drug Interventions

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CROs in Lebanon

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