Clinical Trials on Symptomatic Treatment of Gastric and Duodenal Ulcers in Canada

Total 66 results

Antibe Therapeutics Inc.

Completed

To Compare the Gastrointestinal Safety of a 14-Day Oral Dosing Regimen of ATB-346 to Sodium Naproxen in Healthy Subjects

Gastric Ulcer

Canada
AstraZeneca

Completed

Study of Esomeprazole 20 mg or 40 mg vs Placebo Effectiveness on the Occurrence of Peptic Ulcers in Subjects on Low Dose Acetylsalicylic Acid (LDA) (Oberon)

Gastric Ulcer | Duodenal Ulcer

United States, Bulgaria, Czech Republic, Korea, Republic of, Russian Federation, South Africa, Philippines, Poland, Romania, Finland, Norway, Canada, Mexico, Argentina, Australia, Germany, Portugal, Slovakia, Thailand, Indonesia
Andalusian Initiative for Advanced Therapies -...
Iniciativa Andaluza en Terapias Avanzadas

Completed

Allogeneic Tissue Engineering (Nanostructured Artificial Human Cornea) in Patients With Corneal Trophic Ulcers in Advanced Stages, Refractory to Conventional (Ophthalmic) Treatment

Severe Trophic Corneal Ulcers Refractory to Conventional Treatment | Sequelae of Previous Trophic Corneal Ulcers

Spain
University Health Network, Toronto
Stryker Endoscopy

Recruiting

The Use of Indocyanine Green to Visualize Blood Flow to the Gastrojejunostomy During Bariatric Surgery.

Obesity, Morbid | Ulcer, Gastric

Canada
Cook Group Incorporated

Completed

Hemostasis of Active Gastrointestinal (GI) Luminal Tract Bleeding (HALT)

Bleeding Peptic Ulcers

United Kingdom, Hong Kong, Canada, Netherlands
AstraZeneca

Terminated

Study Comparing Esomeprazole and ASA Combined Together as One Capsule Versus These Medications Taken Separately

Peptic Ulcer Disease

Canada
AstraZeneca

Completed

Study Comparing Esomeprazole and Acetylsalicylic Acid (ASA) Combined Together as One Capsule Versus These Medications Taken Separately

Peptic Ulcer Disease

Canada
Cook Group Incorporated

Completed

EVOLUTION® Duodenal Stent for Duodenal or Gastric Outlet Obstruction Caused by Malignant Neoplasms

Gastric Outlet Obstruction | Duodenal Obstruction

Australia, Netherlands, Canada, Czech Republic, Italy
Takeda

Terminated

A Safety and Efficacy Study of Lansoprazole in Preventing Aspirin-Induced Gastric and Duodenal Ulcers

Duodenal Ulcer | Stomach Ulcer

Japan
Abbott Medical Devices

Active, not recruiting

Cardiovascular Outcomes Assessment of the MitraClip Percutaneous Therapy for Heart Failure Patients With Functional Mitral Regurgitation (The COAPT Trial) and COAPT CAS (COAPT)

Heart Failure | Mitral Regurgitation | Mitral Valve Regurgitation | Treatment of Functional Mitral Regurgitation in Symptomatic Heart Failure Subjects

United States, Canada
Precirix

Terminated

A Study to Evaluate Safety, Tolerability, Dosimetry, and Preliminary Efficacy of the HER2 Directed Radioligand CAM-H2 in Patients With Advanced/Metastatic HER2-Positive Breast, Gastric, and Gastro-Esophageal Junction (GEJ) Cancer

Advanced/Metastatic HER2-positive Breast, Gastric, Gastroesophageal Junction Cancer With Disease Progression Following Anti-HER2 Standard of Care Treatment

United States, Canada
DeCell Technologies Inc.
Canadian Institutes of Health Research (CIHR); Dalhousie University; Lakehead...

Not yet recruiting

Examining the Effectiveness of DermGEN™ in the Treatment of Diabetic Foot Ulcers in First Nations People

Diabetes Mellitus | Diabetic Foot Ulcer | Wound; Foot | Wound of Skin | Tissue Injury | Ulcer Foot | Ulcer Healing | Non-healing Wound

Canada
St. Joseph's Healthcare Hamilton
University Health Network, Toronto; Judy Dan Research and Treatment Centre...

Completed

Hyperbaric Oxygen Therapy (HBOT) for Chronic Diabetic Lower Limb Ulcers (HBOT)

Diabetes Mellitus | Chronic Ulcers of the Lower Limb

Canada
Hamilton Health Sciences Corporation
Tehran University of Medical Sciences; Tohoku University

Recruiting

Japanese Upper GI Symptoms Compared With Iranian and Canadian Patients Presenting

Functional Dyspepsia | Peptic Ulcer | Gastro Esophageal Reflux | Normal Control

Canada, Iran, Islamic Republic of, Japan
The Hospital for Sick Children
Pediatric Oncology Group of Ontario

Completed

Outpatient Yoga Study for Adolescents Receiving Chemotherapy

Quality of Life | Feasibility | Psychological Distress | Pediatric Cancer | Cancer, Treatment-Related | Yoga

Canada
Samuel Lunenfeld Research Institute, Mount Sinai...

Terminated

Gastric Emptying Following an Oral Carbohydrate Load in Women Admitted for Elective Cesarean Delivery

Pregnancy | Respiratory Aspiration of Gastric Contents

Canada
Samuel Lunenfeld Research Institute, Mount Sinai...

Completed

Intra- and Interrater Reliability of Quantitative Ultrasound Assessment of Gastric Content in Term Parturients Before Elective Caesarean Delivery

Pregnancy | Respiratory Aspiration of Gastric Content

Canada
CHU de Quebec-Universite Laval
Canadian Institutes of Health Research (CIHR)

Completed

Treatment of Depressive Symptoms in Breast Cancer Patients: Comparison of Cognitive Therapy and Bright Light Therapy

Treatment of Depressive Symptoms in Cancer Patients

Canada
STEBA France

Suspended

Efficiency Study of S-Tenatoprazole-Na to Treat Erosive or Ulcerative Esophagitis

Esophagitis, Reflux

Canada
University of Manitoba
Victoria General Hospital Foundation

Unknown

Does Participation in a Pre-Operative Physical Activity Program Improve Patient Outcomes and Quality of Life?

Quality of Life | Obesity | Exercise | Bariatric Surgery | Roux-En-Y Gastric Bypass

Canada
National Cancer Institute (NCI)

Completed

Saracatinib in Treating Patients With Locally Advanced or Metastatic Stomach or Gastroesophageal Junction Cancer

Adenocarcinoma of the Gastroesophageal Junction | Stage IV Gastric Cancer | Recurrent Gastric Cancer | Stage III Gastric Cancer | Adenocarcinoma of the Stomach | Stage IV Esophageal Cancer | Stage III Esophageal Cancer

Canada, United States
Takeda

Completed

Efficacy and Safety of Dexlansoprazole MR Compared to Placebo on Maintaining Healing in Subjects With Healed Erosive Esophagitis

Esophagitis, Peptic | Esophagitis, Reflux

United States, Canada, Czech Republic, Lithuania, Slovakia, Latvia, Estonia, Australia
NoNO Inc.

Completed

A Phase 1 Study to Evaluate Safety and Tolerability of NoNO-42 in Healthy Adults

First-In-Human Study to Evaluate Safety of a New Drug Intended for Treatment of Acute Ischemic Stroke

Canada
The Hospital for Sick Children
University of Calgary

Completed

Medi-Port Pilot Randomized Controlled Trial

Actively Undergoing Cancer Treatment | 4-9 Years of Age | At Least 1 Month From Diagnosis | Able to Speak and Understand English | Presenting to Clinic for at Least a 2nd Subcutaneous Port Needle Insertion

Canada
Takeda

Completed

Efficacy and Safety of Dexlansoprazole MR and Lansoprazole on Healing of Erosive Esophagitis

Esophagitis, Peptic | Esophagitis, Reflux

United States, Poland, Bulgaria, India, South Africa, Canada, Peru, New Zealand, Australia, Lithuania, Slovakia, Hungary, Latvia, Germany, Czech Republic
Takeda

Completed

Efficacy and Safety of Dexlansoprazole MR and Lansoprazole on Healing of Erosive Esophagitis

Esophagitis, Peptic | Esophagitis, Reflux

United States, Poland, Bulgaria, India, Canada, Peru, Russian Federation, Australia, New Zealand, Czech Republic, Slovakia, South Africa, Latvia, Lithuania, Colombia, Germany
Wyeth is now a wholly owned subsidiary of Pfizer
Nycomed

Completed

Study Evaluating Pantoprazole in Children With Gastroesophageal Reflux Disease (GERD)

Gastroesophageal Reflux

United States, Canada
Eisai Co., Ltd.

Completed

Quality of Life in New Treatable Therapy as Rabeprazole Option for Refractory Reflux Esophagitis

Refractory Reflux Esophagitis

Japan
Takeda

Recruiting

A Study of Dexlansoprazole Delayed-Release Capsules to Treat Symptomatic Nonerosive Gastroesophageal Reflux Disease in Children

Gastroesophageal Reflux Disease (GERD)

United States, Lithuania, Mexico, Canada, Colombia, Poland
National Cancer Institute (NCI)

Completed

Akt Inhibitor MK2206 in Treating Patients With Advanced Gastric or Gastroesophageal Junction Cancer

Recurrent Gastric Carcinoma | Adenocarcinoma of the Gastroesophageal Junction | Diffuse Gastric Adenocarcinoma | Gastric Intestinal Type Adenocarcinoma | Gastric Mixed Adenocarcinoma

United States, Canada
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Open Label Safety Study of Enteric-Coated Spheroid Suspension in Infants Aged Less Than 12 Months With Presumed Gastroesophageal Reflux Disease (GERD)

Gastroesophageal Reflux

Belgium, Italy, United States, Australia, Canada, France, Germany, Netherlands, Poland, South Africa, Switzerland
Pfizer

Completed

A Trial In Diabetic Patients To Assess Effect Of CE-326,597 On Glucose Control And Body Weight

Weight Management | Treatment Of Obesity

Canada, United States, Bulgaria, Spain, Mexico, India, Puerto Rico
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI); University College, London; McMaster University and other collaborators

Completed

Measuring Patient Satisfaction With Facial Appearance: Development and Validation of a New Patient-Reported Outcome Measure

Head and Neck Cancer | Psychosocial Effects of Cancer and Its Treatment

United States, Canada, United Kingdom
Brock University

Not yet recruiting

Mad Dog Cooking Class Series: Effects on Dietary Self-efficacy, Eating Behaviors and Health Outcomes

Depression | Multiple Sclerosis | Inflammation | Spinal Cord Injuries | Diet, Healthy | Adherence, Treatment

Canada
Ironwood Pharmaceuticals, Inc.

Completed

Trial of IW-3718 for 8 Weeks in Patients With Persistent Gastroesophageal Reflux Disease (GERD) Receiving Proton Pump Inhibitors (PPIs)

Gastroesophageal Reflux Disease (GERD)

United States, Canada
Eisai Inc.

Completed

Rabeprazole Extended-Release 50 mg Versus Esomeprazole 40 mg for Healing and Symptomatic Relief of Moderate to Severe Erosive Gastroesophageal Reflux Disease (GERD)

Gastroesophageal Reflux Disease (GERD)

Canada, Chile, Hungary, Bulgaria, Estonia, Latvia, United States, Croatia, Australia, India, Argentina, France, Germany
Ironwood Pharmaceuticals, Inc.

Terminated

A Trial of IW-3718 for 8 Weeks in Patients With Persistent Gastroesophageal Reflux Disease (GERD) Receiving Proton Pump Inhibitors (PPIs)

Gastroesophageal Reflux Disease (GERD)

Canada, United States
XenoPort, Inc.

Completed

A Study to Evaluate the Efficacy and Safety of Arbaclofen Placarbil (XP19986) as Adjunctive Therapy in Subjects With Gastroesophageal Reflux Disease (GERD)

Gastroesophageal Reflux Disease

United States, Canada
Eisai Inc.

Completed

Rabeprazole Extended-Release, 50 mg, Versus Esomeprazole, 40 mg, for Healing and Symptomatic Relief of Moderate to Severe Erosive Gastroesophageal Reflux Disease (GERD)

Gastroesophageal Reflux Disease (GERD)

Chile, Canada, United States, Estonia, India, Hungary, Bulgaria, Croatia, Australia, Lithuania, Latvia, Argentina, France, Germany
Novartis Pharmaceuticals

Completed

A Phase I Study of LJM716 in Squamous Cell Carcinoma of Head and Neck, or HER2+ Breast Cancer or Gastric Cancer

Squamous Cell Carcinoma of Head and Neck | Esophageal Squamous Cell Carcinoma | HER2 + Breast Cancer, HER2 + Gastric Cancer, Squamous Cell Carcinoma of Head and Neck, Esophageal Squamous Cell Carcinoma | HER2 + Breast Cancer | HER2 + Gastric Cancer

Taiwan, Spain, Canada, Korea, Republic of, United States
Takeda

Completed

Effect of Pantoprazole on the Symptoms of Acid Reflux Disease in Adult Patients (BY1023/M3-341)

Gastroesophageal Reflux Disease (GERD)

United Kingdom, Australia, Belgium, Spain, Austria, Germany, Argentina, Brazil, Canada, France, Hong Kong, India, Italy, Korea, Republic of, Malaysia, Mexico, Poland, Portugal, Singapore, South Africa, Switzerland, Taiwan
Braintree Laboratories

Completed

Safety and Efficacy Study of Axid Use in Infants Suffering From Gastroesophageal Reflux Disease (GERD)

Gastroesophageal Reflux Disease | GERD | Heartburn

United States
Southwest Oncology Group
National Cancer Institute (NCI)

Completed

S9832: Effectiveness of Telephone Counseling By Breast Cancer Survivors on the Well-Being of Women With Recurrent Breast Cancer

Breast Cancer | Psychosocial Effects of Cancer and Its Treatment

United States, Canada
Radiation Therapy Oncology Group
National Cancer Institute (NCI); NRG Oncology

Completed

Radiation Therapy in Treating Patients With Prostate Cancer

Sexual Dysfunction | Prostate Cancer | Radiation Toxicity | Psychosocial Effects of Cancer and Its Treatment

United States, Canada
Amgen

Completed

A Study to Assess the Long-term Safety and Efficacy of Erenumab (AMG 334) in Chronic Migraine Prevention.

Treatment for Prevention of Chronic Migraine

United States, United Kingdom, Poland, Germany, Czechia, Sweden, Canada, Denmark, Finland, Norway
Amgen

Completed

A Study to Evaluate the Efficacy and Safety of Erenumab (AMG 334) in Chronic Migraine Prevention

Treatment for Prevention of Chronic Migraine

United States, United Kingdom, Poland, Germany, Czechia, Sweden, Canada, Denmark, Finland, Norway
Bayer

Active, not recruiting

A Study to Learn How Safe the Study Treatment BAY94-9027 is and How it Affects the Body in Previously Treated Children Aged 7 to Less Than 12 Years With Severe Hemophilia A, a Genetic Bleeding Disorder That is Caused by the Lack of a Protein Called Clotting Factor 8 (FVIII) in the Blood (Alfa-PROTECT)

Hemophilia A | Children | Prophylaxis of Bleeding | Treatment of Bleeding

Canada, United States, Brazil, Italy, Turkey, Argentina, Norway
Centre hospitalier de l'Université de Montréal...
Fonds de la Recherche en Santé du Québec

Terminated

Comparison of OraQuick HCV Rapid Antibody Test and Standard Serologic Screening for Hepatitis C: Validity, Acceptability and Impact on Linkage to Care

Active or Ex-injection Drug Users | Indication of Hepatitis C Screening

Canada
Ferring Pharmaceuticals

Completed

Canadian Active & Maintenance Modified Pentasa Study (CAMMP)

Active Ulcerative Colitis | Remission of Ulcerative Colitis

Canada
Shaare Zedek Medical Center

Completed

Manipulating the Microbiome in IBD by Antibiotics and FMT (FMT)

Exacerbation of Ulcerative Colitis | Ulcerative Colitis, Active Severe | Crohn's Colitis

Israel, Italy, Canada, Finland, Poland, Spain

Clinical Trials on Symptomatic Treatment of Gastric and Duodenal Ulcers in Canada

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