Clinical Trials on Systemic Mycosis

Total 195118 results

Assistance Publique - Hôpitaux de Paris

Terminated

Endoscopic Surgical Treatment of Rhino-Sinusal Mucormycosis (MICCA)

Rhinocerebral Mucormycosis

France
Werner J. Heinz
Merck Sharp & Dohme LLC

Completed

Pharmacokinetic, Safety and Efficacy of Intermittent Application of Caspofungin for Antifungal Prophylaxis (CASPHYLAX)

Fungal Infection

Germany
European Organisation for Research and Treatment...

Completed

Comparison of Voriconazole and Amphotericin B in Treating Patients With Aspergillosis

Infection | Pulmonary Complications

France, Spain, Switzerland, Australia, Sweden, Luxembourg, Belgium, Germany, United Kingdom, Hungary, Italy, Israel, Ireland, Netherlands, United States
National Institute of Allergy and Infectious Diseases...

Completed

Comparison of Two Treatments to Prevent Invasive Fungal Infections in Patients Who Have Received Liver Transplants

Candidiasis

United States
Eunice Kennedy Shriver National Institute of Child...

Terminated

Micafungin Lock Therapy

Catheter-Related Fungal Infections

United States
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Aspergillosis and Humoral Alveolar Immunity by Proteomics (ASPEOMIC)

Aspergillus Fumigatus Infection
Astellas Pharma China, Inc.

Terminated

Post Marketing Study to Evaluate the Safety and Efficacy of Micafungin Against Fungal Infections Caused by Candida Spp or Aspergillus Spp

Candidiasis | Aspergillosis

China
Brynn Chappell
The Christie NHS Foundation Trust

Suspended

Individualisation of Voriconazole Antifungal Therapy Antifungal Therapy (PIVOTAL)

Aspergillosis | Immunocompromised Patient | Fusarium

United Kingdom
John Kitchens, MD

Unknown

Treatment for Presumed Ocular Histoplasmosis (HANDLE)

Ocular Histoplasmosis

United States
University of Pittsburgh
National Center for Research Resources (NCRR)

Completed

Voriconazole Prophylaxis Against Aspergillosis in Lung Transplant Recipients

Post Lung Transplantation

United States
Radboud University Medical Center

Recruiting

Pharmacokinetics of Fluconazole in Children (2-18 Years) (FOCUS)

Invasive Fungal Infections

Netherlands
Postgraduate Institute of Medical Education and...

Completed

Combined Inhalational With Intravenous Amphotericin B Versus Intravenous Amphotericin B Alone for Pulmonary Mucormycosis

Pulmonary Mucormycosis

India
University Hospital Muenster
Merck Sharp & Dohme LLC; Gilead Sciences

Completed

A Study of Caspofungin, Liposomal Amphotericin B or the Combination of Both for Patients After Stem-Cell Transplantation

Hematopoietic Stem Cell Transplantation | Fungus Diseases

Germany
University of Pittsburgh

Terminated

An Assessment of Voriconazole Pharmacokinetics and Pharmacogenetics in Liver Transplant Recipients - Pilot Study

Fungal Infection | Liver Transplant

United States
University of Florida

Terminated

Incidence of Oral Candidiasis, Prevalence of C. Dubliniensis in HIV Patients and In-vitro Azole Susceptibility (ICONIC)

HIV Infections | Candidiasis

United States
Centre Hospitalier Universitaire Dijon

Unknown

Study of Innate Host Immune Response to C. Glabrata Clinical Isolates Resistant to Echinocandins: Impact on the Management of Candidemia in High-risk Patients (CAHOHR)

Candidemia of C. Glabrata

France
Astellas Pharma Inc

Completed

Study of Mycamine® in Children With Fungal Infections to Evaluate Safety and Blood Levels of the Drug

Candidemia | Invasive Candidiasis | Esophageal Candidiasis | Oropharyngeal Candidiasis

United States, South Africa
Astellas Pharma Inc

Completed

Study of Mycamine® in Infants and Toddlers With Fungal Infections to Evaluate Safety and Blood Levels of the Drug

Candidemia | Invasive Candidiasis | Esophageal Candidiasis | Oropharyngeal Candidiasis

United States
Basilea Pharmaceutica

Completed

An Open-label Study of APX001 for Treatment of Patients With Candidemia/Invasive Candidiasis Caused by Candida Auris (APEX)

Candidemia | Candida Infection | Invasive Candidiases

South Africa
University of Minnesota

Recruiting

Optimizing the Dose of Flucytosine for the Treatment of Cryptococcal Meningitis

Cryptococcal Meningitis

Uganda
Instituto de Investigación Hospital Universitario...

Unknown

Effectiveness and Efficiency of a Voriconazole Preemptive Genotyping Strategy (VORIGENPHARM)

Invasive Fungal Infections

Spain
Merck Sharp & Dohme LLC

Completed

Open Label Study of Posaconazole in the Treatment of Invasive Fungal Infections (Study P00041)

Mycoses
PETHEMA Foundation
GTEI; SEMICYUC

Completed

Acetato de Caspofungin (Cancidas®) in the Treatment of Fungal Infection

Candidiasis | Aspergillosis

Spain
National Institute of Allergy and Infectious Diseases...

Completed

An Open Label, Non-Comparative, Multicenter, Phase III Trial of the Efficacy, Safety and Toleration of Voriconazole in the Primary or Secondary Treatment of Invasive Fungal Infections

Mycoses

United States
Shanghai Children's Medical Center

Not yet recruiting

Study on Theraputic Drug Monitoring and Phamacokinetics of Isavuconazole in Children

Mucormycosis | Aspergillosis Invasive
Pfizer

Completed

Patterns of Real-World Isavuconazole Use - a Study of Patients With Mucormycosis or Invasive Aspergillosis (PRISMA)

Mucormycosis | Invasive Aspergillosis

Spain, Germany, France, United Kingdom, Italy
L.V. Prasad Eye Institute

Unknown

Combination Treatment of 5% Natamycin and 1% Voriconazole in Fungal Keratitis (NATA_VORI)

Infection, Fungal

India
London School of Hygiene and Tropical Medicine
University of Zimbabwe; Botswana Harvard AIDS Institute Partnership; Infectious...

Completed

The Lived Experience of Participants in an African Randomised Trial (LEOPARD)

HIV | Cryptococcal Meningitis

Zimbabwe, Botswana, Uganda
University of Minnesota
Centers for Disease Control and Prevention; Makerere University; Infectious Diseases...

Completed

Operational Research for Cryptococcal Antigen Screening (ORCAS)

Cryptococcosis | Cryptococcal Meningitis | Cryptococcus Neoformans

Uganda
National Institute of Allergy and Infectious Diseases...

Completed

High-Dose Fluconazole for the Treatment of Cryptococcal Meningitis in HIV-Infected Individuals

HIV Infections | Cryptococcal Meningitis

Kenya, Thailand, Uganda, United States, Peru, South Africa, Zimbabwe, India
First Affiliated Hospital of Zhejiang University
Wenzhou Central Hospital

Unknown

Three Induction Treatments on Cryptococcal Meningitis (TITOC)

HIV/AIDS | Cryptococcal Meningitis

China
University of Minnesota
National Institute of Neurological Disorders and Stroke (NINDS); Medical Research... and other collaborators

Completed

Adjunctive Sertraline for the Treatment of HIV-Associated Cryptococcal Meningitis (ASTRO-CM)

Cryptococcal Meningitis | Fungal Meningitis

Uganda
ANRS, Emerging Infectious Diseases
Institut Pasteur; Hôpital Necker-Enfants Malades; Hospital Avicenne; CHU Kamenge... and other collaborators

Unknown

Study Evaluating Efficiency and Tolerance of High-dose Fluconazole Associated With Flucytosine as Induction Therapy for Cryptococcal Meningitis Associated With HIV in Sub-saharan Africa (Flucocrypto)

HIV | Cryptococcal Meningitis

Burundi, Côte D'Ivoire
Imagine Institute

Recruiting

European Study of Cerebral Aspergillosis Treated With Isavuconazole (ESCAI)

Invasive Aspergillosis | Cerebral Aspergillosis

France
Children's Mercy Hospital Kansas City

Completed

Genetic Variation and Variability in Posaconazole Pharmacokinetics in Children

Fungal Infections

United States
Singapore General Hospital
National University Hospital, Singapore

Completed

To Determine Whether Galactomannan Test Will Help to Detect Fungal Infections Early and Hence Start Treatment Early

Aspergillosis

Singapore
Bill McGhee
Astellas Pharma Inc

Completed

Antifungal Locks to Treat Fungal-related Central Line Infections

Central Line Fungal Infections

United States
Astellas Pharma Inc

Withdrawn

A Study to Evaluate the Effectiveness of Voriconazole + Micafungin Versus Voriconazole Alone for Invasive Aspergillosis

Aspergillosis/Blood | Aspergillosis/Invasive

United States
University of Zimbabwe
AIDS Care Research in Africa

Completed

Early Versus Delayed Antiretroviral Therapy (ART) in the Treatment of Cryptococcal Meningitis in Africa

HIV Infections | Cryptococcal Meningitis

Zimbabwe
Botswana-UPenn Partnership
University of Pennsylvania; Doris Duke Charitable Foundation

Completed

Optimal Time to Start Antiretroviral Therapy in HIV-infected Adults With Cryptococcal Meningitis (Crypto)

HIV Infections | Cryptococcal Meningitis

Botswana
Karolinska University Hospital

Completed

Value of PCT When Diagnosing Candidemia

The Value of Procalcitonin in Patients With Suspected Candidemia

Sweden
University of Houston
Merck Sharp & Dohme LLC

Completed

Clinical Outcomes in Candidemia Patients Based on in Vitro Susceptibility

Candida | Blood Stream Infections
Peking Union Medical College Hospital

Recruiting

To Evaluate the Efficacy and Safety of ABCD in the Treatment of IFD

Invasive Fungal Disease

China
National Institute of Allergy and Infectious Diseases...

Completed

Safety and Pharmacokinetics of VT-1598

Coccidioidomycosis

United States
University of California, San Francisco

Withdrawn

Sertraline in Addition to Standard of Care Treatment for Coccidioidomycosis

Coccidioidomycosis
Astellas Pharma Global Development, Inc.

Completed

Registry of Patients Treated With Systemic Mold-Active Triazoles

Invasive Fungal Infection

United States
Merck Sharp & Dohme LLC

Terminated

A Study of the Safety, Tolerance, and Pharmacokinetics of Oral Posaconazole in Immunocompromised Children (P03579)

Fungal Infections
University of Sao Paulo

Completed

Clinical and Laboratorial Evaluation of the Desinfection Solutions in Candida Species From Total Prostheses and Palate of Total Edentulous.

Candidiasis | Candida Infection | Biofilms
Merck Sharp & Dohme LLC

Completed

Study of Posaconazole in the Treatment of Invasive Fungal Infections (Study P02095)

Mycoses
Asan Medical Center

Withdrawn

Voriconazole Plasma Level in Intensive Care Unit (ICU) Patients

Invasive Fungal Infection

Korea, Republic of

Clinical Trials on Systemic Mycosis

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