Clinical Trials on Temporomandibular Joint Osteoarthritis in United States

Total 4309 results

Bristol-Myers Squibb

Terminated

Proof of Concept Study to Evaluate the Efficacy and Safety of BMS-931699 (Lulizumab) or BMS-986142 in Primary Sjögren's Syndrome

Sjögren's Syndrome

Australia, United States, Italy, Mexico, Colombia, Peru, Puerto Rico, South Africa, Chile, Poland, Russian Federation
Allergan

Completed

Six Month Clinical Research Study for Patients With Moderate or Severe Dry Eye Syndrome

Arthritis, Rheumatoid | Lupus Erythematosus, Systemic | Scleroderma, Systemic | Keratoconjunctivitis Sicca | Sjogren's Syndrome

United States
Takeda

Completed

Efficacy and Safety of Oral Febuxostat in Participants With Gout (CONFIRMS)

Gout

United States
LG Chem

Recruiting

Tigulixostat, Phase 3 Study, Allopurinol Controlled in Gout Patients (EURELIA2)

Hyperuricemia | Gout | Gout Flare | Tophi

United States
Novartis Pharmaceuticals

Completed

Safety and Efficacy of Canakinumab Prefilled Syringes in Frequently Flaring Acute Gouty Arthritis Patients

Acute Gouty Arthritis

Hungary, Germany, United States, Lithuania, Canada
Pfizer
Hospira, now a wholly owned subsidiary of Pfizer

Completed

Post-Marketing Use Of CT-P13 (Infliximab) For Standard Of Care Treatment Of Rheumatoid Diseases Who Are Naïve To Biologics Or Switched From Remicade (PERSIST)

Rheumatoid Arthritis | Psoriatic Arthritis | Ankylosing Spondylitis | Rheumatoid Diseases

Spain, Canada, Greece, United Kingdom, Germany, Bulgaria, Czechia
Newcastle-upon-Tyne Hospitals NHS Trust

Recruiting

Global Registry for COL6-related Dystrophies

Bethlem Myopathy | Ullrich Congenital Muscular Dystrophy 1, Digenic, Col6A1/Col6A2 | Ullrich Congenital Muscular Dystrophy 1, Autosomal Recessive | Ullrich Congenital Muscular Dystrophy 1, Autosomal Dominant | Bethlem Myopathy 1, Autosomal Recessive | UCMD | BTHLM1

United Kingdom
Amgen

Recruiting

Apremilast Pediatric Study in Children With Active Juvenile Psoriatic Arthritis (PEAPOD)

Active Juvenile Psoriatic Arthritis

Spain, Turkey, Belgium, France, Greece, Italy, United Kingdom, Austria, Germany, Netherlands, Poland, Romania, Lithuania, South Africa, Portugal
Jonsson Comprehensive Cancer Center
National Cancer Institute (NCI); Highlight Therapeutics

Active, not recruiting

Nivolumab and BO-112 Before Surgery for the Treatment of Resectable Soft Tissue Sarcoma

Leiomyosarcoma | Malignant Peripheral Nerve Sheath Tumor | Synovial Sarcoma | Undifferentiated Pleomorphic Sarcoma | Undifferentiated High Grade Pleomorphic Sarcoma of Bone | Myxofibrosarcoma | Stage II Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8 | Stage III Soft Tissue Sarcoma of the... and other conditions

United States
University of Nottingham

Completed

Monitoring of Inflammatory Conditions

Rheumatoid Arthritis | Psoriasis | Crohn Disease | Inflammatory Arthritis | Ulcerative Colitis | Psoriatic Arthritis | Reactive Arthritis | Inflammatory Disease | System; Lupus Erythematosus

United Kingdom
Novartis Pharmaceuticals

Recruiting

A Randomized, Double-blind 2-arm NEPTUNUS Extension Study to Assess the Long-term Safety and Efficacy of Ianalumab in Patients With Sjogrens Syndrome. (NEPTUNUS-Ext)

Sjogrens Syndrome

United States, Spain, Austria, Belgium, Japan, Poland, Germany, Turkey, Hungary, Israel, Italy, France, Portugal, Taiwan, Australia, Slovakia, United Kingdom, Guatemala, Brazil, Czechia, Bulgaria, Canada, Argentina, Lithuania, Romania
Novartis Pharmaceuticals

Completed

Study of Safety and Efficacy of Multiple Doses of CFZ533 in Two Distinct Populations of Patients With Sjogren's Syndrome (TWINSS)

Sjögren Syndrome

United States, United Kingdom, Netherlands, Australia, Austria, Israel, France, Germany, Greece, Hungary, Italy, Korea, Republic of, Japan, Portugal, Russian Federation, Turkey, Canada, Colombia, Romania, Argentina, Chile, Brazil, S...
Bristol-Myers Squibb

Completed

A Study to Assess the Efficacy and Safety of Abatacept in Adults With Active Primary Sjögrens Syndrome

Sjogrens Disease

United States, France, Italy, Sweden, Japan, Australia, Mexico, Argentina, Brazil, Korea, Republic of, Czechia, Puerto Rico, Germany
University of Alabama at Birmingham
Oregon Health and Science University

Completed

Safety and Effectiveness of Live Zoster Vaccine in Anti-Tumor Necrosis Factor (TNF) Users (VERVE Trial)

Arthritis | Rheumatoid Arthritis | Psoriasis | Crohn's Disease | Inflammatory Arthritis | Psoriatic Arthritis | Ankylosing Spondylitis | Enteropathic Arthritis

United States
Momentum Data
Pfizer; University of Surrey

Completed

The Risk of Venous Thromboembolism in Systemic Inflammatory Disorders: a United Kingdom (UK) Matched Cohort Study

Rheumatoid Arthritis | Inflammatory Bowel Diseases | Crohn Disease | Deep Vein Thrombosis | Ulcerative Colitis | Venous Thromboembolism | Psoriatic Arthritis | Pulmonary Embolism | Venous Thromboses

United Kingdom
Mayo Clinic

Completed

Spontaneous Coronary Artery Dissection (SCAD) and Autoimmunity

Multiple Sclerosis | Rheumatoid Arthritis | Systemic Lupus Erythematosus | Uveitis | Vasculitis | Psoriasis | Graves Disease | Systemic Sclerosis | Celiac Disease | Crohn Disease | Type 1 Diabetes Mellitus | Myasthenia Gravis | Ulcerative Colitis | Dermatomyositis | Polymyositis | Vitiligo | Hepatitis, Autoimmune | Polymyalgia... and other conditions

United States
Allena Pharmaceuticals

Terminated

Phase IIa Study of ALLN-346 (Engineered Urate Oxidase) in Subjects With Hyperuricemia, Gout and Chronic Kidney Disease

Chronic Kidney Diseases | Hyperuricemia | Gout

United States
National Cancer Institute (NCI)

Terminated

Navitoclax and Vistusertib in Treating Patients With Relapsed Small Cell Lung Cancer and Other Solid Tumors

Refractory Malignant Solid Neoplasm | Recurrent Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm | Unresectable Solid Neoplasm | Recurrent Lung Small Cell Carcinoma | Stage IIIA Lung Small Cell Carcinoma AJCC v7 | Stage IIIB Lung Small Cell Carcinoma AJCC v7 | Stage IV Lung Small Cell... and other conditions

United States
Alder Hey Children's NHS Foundation Trust

Completed

The LAVA (Lateral Flow Antigen Validation and Applicability) Study for COVID-19 (LAVA)

Covid19 | This is a Pilot Study Which Aims to Assess the Validity and Applicability of Lateral Flow Assays (LFAs) Which Can be Used as a Point of Care Test for COVID-19

United Kingdom
Otsuka Pharmaceutical Development & Commercialization...

Completed

8-Week Study of Tolvaptan Dose Forms in Autosomal Dominant Polycystic Kidney Disease (ADPKD) (NOCTURNE)

Autosomal Dominant Polycystic Kidney Disease

United States
GlaxoSmithKline

Completed

Safety and Efficacy Study of Subcutaneous Belimumab and Intravenous Rituximab Co-administration in Subjects With Primary Sjogren's Syndrome

Sjogren's Syndrome

Spain, France, Germany, Netherlands, United Kingdom, Sweden, Argentina, Italy, Canada, Norway
Takeda

Completed

Efficacy and Safety of Extended Release and Immediate Release Febuxostat in Participants With Gout and Moderate Renal Impairment

Gout | Moderate Renal Impairment

United States
King's College London

Recruiting

The Living With a Long-Term Condition Study (LTC)

Liver Diseases | Heart Diseases | Heart Failure | Stroke | Cerebrovascular Disorders | Epilepsy | Pain | Multiple Sclerosis | Hypertension | Obesity | Diabetes | Cancer | Arthritis | Osteoarthritis | Rheumatoid Arthritis | Parkinson Disease | Migraine | Hepatitis | Atrial Fibrillation | Asthma | Endometriosis | Dementia | Fibromyalgia | Celiac... and other conditions

United Kingdom
Novartis Pharmaceuticals

Recruiting

Two-arm Study to Assess Efficacy and Safety of Ianalumab (VAY736) in Patients With Active Sjogren's Syndrome (NEPTUNUS-1)

Sjogren Syndrome

United States, Belgium, Austria, Brazil, Mexico, Portugal, Turkey, Spain, Chile, Poland, Germany, Guatemala, Korea, Republic of, Czechia, France, China, Lithuania, Singapore
Sanguine Biosciences

Recruiting

Tissue Repository Providing Annotated Biospecimens for Approved Investigator-directed Biomedical Research Initiatives

Heart Diseases | Stroke | Lymphoma | Multiple Sclerosis | Kidney Diseases | Diabetes | Leukemia | Age-Related Macular Degeneration | Cancer | Arthritis | Schizophrenia | Thyroid Diseases | Parkinson Disease | Hepatitis | Vasculitis | Psoriasis | Asthma | Amyloidosis | Fibromyalgia | Graves Disease | Alzheimer Disease | Celiac Disease | Cirr... and other conditions

United States
Novartis Pharmaceuticals

Completed

Study of Efficacy and Safety of Secukinumab in Psoriatic Arthritis and Axial Spondyloarthritis Patients With Active Enthesitis Including One Achilles Tendon Site (ACHILLES)

Psoriatic Arthritis | Enthesitis | Axial Spondyloarthritis

Germany, Spain, United Kingdom, Greece, Bulgaria, Italy, Czechia, Slovakia
Oxford University Hospitals NHS Trust

Active, not recruiting

Short or Long Antibiotic Regimes in Orthopaedics (SOLARIO)

Diabetic Foot | Prosthetic Joint Infection | Osteomyelitis

United Kingdom, Germany, Spain, Portugal
University of Nottingham

Completed

Vaccination Perception in Inflammatory Conditions - Flu, Pneumonia and COVID-19 (OPINION)

Rheumatoid Arthritis | Systemic Lupus Erythematosus | Inflammatory Bowel Diseases | Vasculitis | Psoriatic Arthritis | Ankylosing Spondylitis | Reactive Arthritis | Inflammatory Disease

United Kingdom
Children's Hospital of Philadelphia
Illumina, Inc.

Active, not recruiting

LeukoSEQ: Whole Genome Sequencing as a First-Line Diagnostic Tool for Leukodystrophies

Mucopolysaccharidoses | Leukodystrophy | Adrenoleukodystrophy | Adrenomyeloneuropathy | X-linked Adrenoleukodystrophy | Gangliosidoses | Metachromatic Leukodystrophy | Krabbe Disease | Refsum Disease | Cadasil | Sjogren-Larsson Syndrome | Allan-Herndon-Dudley Syndrome | White Matter Disease | GM2 Gangliosidosis | Zellweger... and other conditions

United States
University of Aberdeen
Versus Arthritis

Completed

Lessening the Impact of Fatigue in Inflammatory Rheumatic Diseases (LIFT)

Rheumatoid Arthritis | Lupus Erythematosus, Systemic | Psoriatic Arthritis | Sjogren's Syndrome | Axial Spondyloarthritis

United Kingdom
UCB Biopharma S.P.R.L.

Completed

Study to Test the Safe and Effective Use of an e-Device for the Self-injection of Certolizumab Pegol Solution by Subjects With Moderate to Severe Active Rheumatoid Arthritis, Active Ankylosing Spondylitis, Active Psoriatic Arthritis, or Moderately to Severely Active Crohn's Disease

Moderate and Severe Active Rheumatoid Arthritis | Active Psoriatic Arthritis | Active Ankylosing Spondylitis | Moderately to Severely Active Crohn's Disease

United States
Bristol-Myers Squibb

Completed

Study to Assess Safety and Effectiveness of Branebrutinib Treatment in Participants With Active Systemic Lupus Erythematosus or Primary Sjögren's Syndrome, or Branebrutinib Treatment Followed by Open-label Abatacept Treatment in Study Participants With Active Rheumatoid Arthritis

Rheumatoid Arthritis | Systemic Lupus Erythematosus | Autoimmune Disorder | Primary Sjögren's Syndrome

United States, Argentina, Belgium, France, Germany, Mexico, Poland, Spain, Netherlands, United Kingdom
Novartis Pharmaceuticals

Recruiting

Three-arm Study to Assess Efficacy and Safety of Ianalumab (VAY736) in Patients With Active Sjogren's Syndrome (NEPTUNUS-2)

Sjogren Syndrome

United States, Spain, Hungary, Germany, Brazil, Israel, Canada, Chile, Colombia, Argentina, Greece, United Kingdom, Australia, Bulgaria, Japan, Mexico, South Africa, China, Lebanon, Taiwan, Italy, France, Romania, India, Poland, Slovakia, S...
Otsuka Pharmaceutical Development & Commercialization...

Completed

Long Term Safety of Immediate-release Tolvaptan in Subjects With Autosomal Dominant Polycystic Kidney Disease

Polycystic Kidney, Autosomal Dominant

Belgium, Germany, Italy, Spain, Sweden, United States, Canada, Australia, Netherlands, Czechia, Poland, Denmark, Israel, Hungary, Russian Federation, South Africa, United Kingdom, Romania, Argentina, Norway
Regulus Therapeutics Inc.

Recruiting

A Study of RGLS8429 in Patients With Autosomal Dominant Polycystic Kidney Disease

Polycystic Kidney, Autosomal Dominant | Autosomal Dominant Polycystic Kidney Disease | ADPKD

United States
Viela Bio

Completed

A Study to Evaluate VIB7734 in Participants With Systemic Lupus Erythematosus (SLE), Cutaneous Lupus Erythematosus (CLE), Sjogren's Syndrome, Systemic Sclerosis, Polymyositis, and Dermatomyositis

Systemic Lupus Erythematosus | Systemic Sclerosis | Dermatomyositis | Polymyositis | Sjogren's Syndrome | Cutaneous Lupus Erythematosus

United States, Poland, Spain
Bristol-Myers Squibb

Recruiting

A Study to Evaluate the Efficacy and Safety of Deucravacitinib in Adults With Active Sjögren's Syndrome (POETYK SjS-1)

Sjögren's Syndrome

United States, Australia, Germany, Austria, China, Korea, Republic of, Puerto Rico, Poland, Japan, Canada, Hungary, Spain, Argentina, Chile, Denmark, France, Italy, Mexico, Peru, Taiwan, Netherlands, Belgium, Brazil, Colombia, United Kingdom and more
Otsuka Pharmaceutical Development & Commercialization...

Completed

Safety, Pharmacokinetics, Tolerability and Efficacy of Tolvaptan in Children and Adolescents With ADPKD (Autosomal Dominant Polycystic Kidney Disease)

Autosomal Dominant Polycystic Kidney Disease (ADPKD)

Germany, Italy, Belgium, United Kingdom
Sylentis, S.A.

Completed

Tivanisiran for Dry Eye in Subjects With Sjögren's Syndrome

Dry Eye Disease | Sjögren Syndrome

United States, Spain
Otsuka Pharmaceutical Development & Commercialization...

Completed

Tolvaptan Extension Study in Participants With ADPKD (TEMPO 4/4)

Autosomal Dominant Polycystic Kidney Disease (ADPKD)

United States, Australia, Belgium, Germany, Italy, Poland, Romania, United Kingdom, Argentina, Canada, France, Netherlands, Russian Federation
VA Office of Research and Development

Completed

CSP594 Comparative Effectiveness in Gout: Allopurinol vs. Febuxostat

Chronic Kidney Diseases | Gout

United States
Otsuka Pharmaceutical Development & Commercialization...
Otsuka Pharmaceutical Co., Ltd.

Completed

Tolvaptan Phase 3 Efficacy and Safety Study in Autosomal Dominant Polycystic Kidney Disease (ADPKD) (TEMPO3:4)

Polycystic Kidney Disease, Autosomal Dominant

United States, Belgium, United Kingdom, Russian Federation, France, Australia, Netherlands, Italy, Japan, Denmark, Romania, Poland, Canada, Argentina, Germany
Ironwood Pharmaceuticals, Inc.
Medpace, Inc.

Terminated

A Phase 4 Safety and Efficacy Study to Evaluate Lesinurad 200 mg in Participants With Gout and Renal Impairment

Gout | Chronic Kidney Disease (CKD)

United States, Hungary, Poland, Czechia
Sanguine Biosciences

Completed

At-Home Research Study for Patients With Autoimmune, Inflammatory, Genetic, Hematological, Infectious, Neurological, CNS, Oncological, Respiratory, Metabolic Conditions

Depression | Melanoma | Epilepsy | Lymphoma | Multiple Sclerosis | Kidney Cancer | Cervical Cancer | Diabetes Mellitus | Leukemia | Breast Cancer | Chronic Kidney Diseases | Chronic Obstructive Pulmonary Disease | Parkinson's Disease | Systemic Lupus Erythematosus | Multiple Myeloma | Hepatitis B | Insomnia | Colorectal Cancer | HIV/AID... and other conditions

United States
Reata, a wholly owned subsidiary of Biogen

Terminated

A Trial of Bardoxolone Methyl in Patients With ADPKD - FALCON (FALCON)

Autosomal Dominant Polycystic Kidney | ADPKD

United States, Spain, United Kingdom, Australia, France, Japan, Germany, Belgium, Czechia, Italy
Alliance Foundation Trials, LLC.
Bristol-Myers Squibb

Terminated

Nivolumab in Patients With Advanced Non-Small Cell Lung Cancer and Pre-existing Autoimmune Disease

Multiple Sclerosis | Autoimmune Diseases | Rheumatoid Arthritis | Systemic Lupus Erythematosus | Psoriasis | Crohn Disease | Ulcerative Colitis | Non-small Cell Lung Cancer | Giant Cell Arteritis | Polymyalgia Rheumatica

United States
Eli Lilly and Company

Active, not recruiting

A Study of Ixekizumab (LY2439821) in Children With Juvenile Idiopathic Arthritis Categories of Enthesitis-related Arthritis (Including Juvenile Onset Ankylosing Spondylitis) and Juvenile Psoriatic Arthritis

Juvenile Psoriatic Arthritis | Enthesitis Related Arthritis

Spain, Belgium, Germany, Italy, United Kingdom, Denmark, Mexico, Netherlands, Switzerland
Otsuka Pharmaceutical Development & Commercialization...
Otsuka Pharmaceutical Co., Ltd.

Completed

Observational Study in Patients With Autosomal Dominant Polycystic Kidney Disease (OVERTURE)

Autosomal Dominant Polycystic Kidney Disease (ADPKD)

United States, Argentina, Australia, Belgium, Brazil, Canada, Czech Republic, France, Germany, Italy, Japan, Netherlands, Norway, Poland, Romania, Spain, Sweden, Switzerland, Turkey, United Kingdom
Otsuka Pharmaceutical Development & Commercialization...

Completed

Efficacy and Safety of Tolvaptan in Subjects With Chronic Kidney Disease Between Late Stage 2 to Early Stage 4 Due to Autosomal Dominant Polycystic Kidney Disease

Chronic Kidney Disease | Autosomal Dominant Polycystic Kidney Disease

Australia, Belgium, Italy, Spain, Sweden, United States, Canada, Netherlands, Czechia, Poland, Germany, Russian Federation, Hungary, Israel, Puerto Rico, Argentina, Denmark, South Africa, United Kingdom, Norway, France, Romania
Biogen

Completed

A Real-world Study of Imraldi® Use (PROPER)

Arthritis, Rheumatoid (RA) | Arthritis, Psoriatic (PsA) | Crohn's Disease (CD) | Colitis, Ulcerative (UC) | Axial Spondyloarthritis (axSpA)

Italy, United Kingdom, Germany, Belgium, Spain, Ireland

Clinical Trials on Temporomandibular Joint Osteoarthritis in United States

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