Clinical Trials on Therapeutic Agent Toxicity

Total 1375 results

Sohag University

Not yet recruiting

Evaluation of the Role of Poisoning Severity Score, Serum Procalcitonin and C-reactive Protein in Acute Hydrocarbon Intoxicated Cases Admitted to the Poison Control Center Ain Shams University Hospitals

Acute Hydrocarbon Toxicity

Egypt
Thomas Jefferson University

Active, not recruiting

Ropivacaine Pharmacokinetics in ESP Blocks

Pain | Quality of Recovery | Local Anesthetic Systemic Toxicity

United States
Montefiore Medical Center

Terminated

Mechanisms and Treatment of Chronic Allograft Injury (CAI) Due to Calcineurin Inhibitor (CNI) Toxicity

Chronic Allograft Injury | Calcineurin Inhibitor Toxicity

United States
National Institutes of Health Clinical Center (CC)

Completed

Probiotic Ingestion and Isoagglutinin Titers

Isoagglutinin-Mediated Hemolysis | Probiotic Toxicity

United States
Muhammad Haroon Anwar
Pakistan Institute of Medical Sciences

Not yet recruiting

Perfusion Index as a Predictor of Hypotension Following Sub-arachnoid Block Among Patients Undergoing Lower Segment Caesarean Section

Hypotension | Spinal Anesthetics Causing Adverse Effects in Therapeutic Use | Hypotension on Induction

Pakistan
Humanitas Clinical and Research Center

Unknown

Transarterial Coil Embolization of the Superior Rectal Arteries for Treatment of Stage II Hemorrhoids

Hemorrhoids | Embolization, Therapeutic

Italy
Rio de Janeiro State University

Completed

Effects of the Use of Platelet-rich Fibrin on Bone Regeneration After Impacted Third Molar Surgery

Molar, Third | Bone Regeneration | Blood Platelets | Fibrin/Therapeutic Use

Brazil
Osprey Medical, Inc

Terminated

Contrast Media Reduction and Removal in Patients With Chronic Kidney Disease (CKD) (PRESERV)

Radiographic Contrast Agent Nephropathy

United States, Germany
Hospital Nord

Completed

Non-invasive Haemodynamic Monitoring to Predict Spinal Hypotension During Caesarian Section

Pregnancy Related | Hypotension | Spinal Anesthetics Causing Adverse Effects in Therapeutic Use

France
Anand Prasad
Osprey Medical, Inc

Terminated

Evaluation of a Novel Method of Contrast Volume Quantification - AVERT PLUS (AVERT-PLUS)

Extravasation of Contrast Media
The Chaim Sheba Medical Center

Withdrawn

Complementary/Integrative Medicine for Brain Cancer Patients

Quality of Life | Radiation Toxicity | Chemotherapeutic Toxicity
Żelazna Medical Centre, LLC
Laboratory of Genetics and Human Genomics, University of Gdańsk

Completed

Genetic Aspects of Vaginal Aging

Genitourinary Agents

Poland
Radboud University Medical Center

Not yet recruiting

Model Informed preciSion doSIng tO iNdividualise and Optimize Pharmacotherapeutic Treatment (MISSION)

Pharmacokinetics | Tacrolimus | Area Under Curve | Immunosuppressive Agents | Mycophenolic Acid
Onconic Therapeutics Inc.

Completed

Compare Pharmacokinetics and Safety of JP-1366 Between Korean and Caucasian

Anti-Ulcer Agents

Korea, Republic of
Annelies Verbon
University Hospital, Geneva; Erasmus Medical Center; Uppsala University Hospital and other collaborators

Unknown

A Digital Antimicrobial Stewardship Smartphone Application to Combat AMR: the AB-assistant (AB-assistant)

Mobile Applications | Quality Improvement | Anti-Infective Agents | Antimicrobial Stewardship

Canada, Netherlands, Sweden, Switzerland
Dr. Krupa NC

Completed

Anticaries Effect of Xylitol,Probiotic and Chlorhexidine Mouth Rinses Among Individuals at High Risk (AEXPC)

Cariostatic Agents | Mouthwashes

India
Dartmouth-Hitchcock Medical Center

Completed

A Survey of Financial Toxicity in Rural Cancer Patients

Financial Toxicity

United States
Attikon Hospital

Completed

Echocardiography and Spinal Induced Hypotension.

Spinal Anesthetic Toxicity

Greece
University of Witwatersrand, South Africa

Terminated

Differences Between Stavudine and Tenofovir Each Combined With Lamivudine and Efavirenz in SA HIV-infected Patients (CHRU01)

Metabolic Complications | Mitochondrial Toxicity

South Africa
Mayo Clinic

Recruiting

Comparative Study of Two Topical Anesthetics Prior to Fractional Nonablative Laser Treatment of the Face

Anesthesia, Local | Photodamaged Skin | Topical and Infiltration Anesthetic Toxicity

United States
National Cancer Institute, Naples

Recruiting

Development and Validation of a Tool for Patient-reported Assessment of Cancer-related Financial Toxicity in Italy (PROFTC-I)

Cancer

Italy
University Medical Center Groningen

Recruiting

Investigating Cardiovascular Adverse Events Related to Cancer Treatment (InvestiCAT)

Toxicity Due to Chemotherapy | Cancer, Treatment-Related | Cardiovascular Morbidity

Netherlands
Jong Hoon Lee

Unknown

Two-week Course Versus Conventionally Fractionated Chemoradiotherapy in Rectal Cancer

Recurrence | Toxicity | Response to Toxin

Korea, Republic of
Cairo University

Not yet recruiting

The Ability Of Inferior Vena Caval Distensibility Index With Passive Leg Raising Test To Predict Spinal Anesthesia-induced Hypotension In Elderly Patients Undergoing Infra-umbilical Surgeries. A Prospective Observational Study.

Spinal Anesthetics Causing Adverse Effects in Therapeutic Use
Assiut University

Unknown

Cyclizine Vs. Dexamethasone for Nausea and Vomiting Following Intrathecal Morphine in Cases of Cesarean Section

Spinal Anesthetics Causing Adverse Effects in Therapeutic Use
Luye Pharma Group Ltd.

Completed

Relative Bioavailability of LY03010 Compared to Listed Drug

Mental Disorders | Psychotic Disorders | Mood Disorders | Schizophrenia | Molecular Mechanisms of Pharmacological Action | Tranquilizing Agents | Physiological Effects of Drugs | Psychotropic Drugs | Antipsychotic Agents | Central Nervous System Depressants | Neurotransmitter Agents | Schizophrenia Spectrum

United States
Mucosa Innovations, S.L.

Completed

Oral Mucositis and Quality of Life With a Mucosa Topical Composition in Head & Neck Cancer Patients.

Quality of Life | Pain | Mucositis | Radiation Toxicity | Chemotherapeutic Toxicity | Oral Mucositis | Saliva | Speech

Spain
Medical University of Lodz

Completed

Omega-3 Polyunsaturated Fatty Acids in Non-surgical Treatment of Periodontitis

Periodontitis | Therapeutics | Fatty Acids, Unsaturated

Poland
Luis Eduardo Morales Buenrostro

Completed

Pharmacokinetic Parameters of Innovative Valganciclovir Versus Generic Valganciclovir

Kidney Transplantation | Pharmacokinetics | Cytomegalovirus Infections | Therapeutic Equivalency

Mexico
Zonguldak Bulent Ecevit University

Completed

AGC Mode vs Minimal Flow in Breast Surgery

Breast Diseases | Anesthesia; Functional | Volatil Agent Consumption | Automatic End-tidal Controlled Anesthesia

Turkey
UCB Pharma

Completed

Facial Thermography Study of Levocetirizine Versus Cetirizine

Anti-allergic Agents
Virginia Commonwealth University
Wake Forest University

Recruiting

Myocardial Perfusion and Fibrosis in Cancer Survivors

Myocardial Fibrosis | Myocardial Injury | Chemotherapeutic Toxicity

United States
Harvard School of Public Health (HSPH)
National Institute on Drug Abuse (NIDA); National Institute on Alcohol Abuse... and other collaborators

Recruiting

Surveillance Monitoring for ART Toxicities Study in HIV Uninfected Children Born to HIV Infected Women (SMARTT)

Antiretroviral Toxicity

United States, Puerto Rico
Hadassah Medical Organization

Unknown

Fertility Preservation by Ovarian and Oocyte Cryopreservation (HFPP)

Female Patients Aged 5-35 Prior to Systemic Chemotherapy | With Significant Risk of Ovarian Toxicity

Israel
Ege University

Not yet recruiting

Comparison Of The Effects Of Carbetocin And Oxytocin In C-Sectıon

Carbetocin | Oxytocic Drugs Causing Adverse Effects in Therapeutic Use

Turkey
University of Yalova

Completed

The Effect Of Therapeutic Touch To Mothers With Preterm Babies

Therapeutic Touch
Wake Forest University Health Sciences

Withdrawn

Phenylephrine Dose and Mode of Administration for Spinal Anesthesia Induced Hypotension

Complications; Cesarean Section | Spinal Anesthetics Causing Adverse Effects in Therapeutic Use

United States
The Hong Kong Polytechnic University
OPHTECS Corporation

Completed

Efficacy and Safety of cleadewGP for Rigid Contact Lenses

Contact Lens Solution Toxicity

Hong Kong
Hannibal Troensegaard

Completed

Supplementary Oxygen in Surgical and Medical Wards Evaluated by 30-day Mortality (SOSAM)

Oxygen Deficiency | Oxygen Toxicity

Denmark
Karolinska University Hospital

Completed

Effect of THRIVE During Apneic Oxygenation in General Anesthesia on Biomarkers (Bio-THRIVE)

Anesthesia | Oxygen Toxicity

Sweden
Jeil Pharmaceutical Co., Ltd.

Completed

Clinical Trial to Investigate the Safety, Tolerability and Pharmacokinetics and Pharmacodynamics of JP-1366 Oral Administration in Healthy Male Subjects

Anti-Ulcer Agents

Korea, Republic of
Hospital de Sant Pau
University of Barcelona

Completed

Study of Iodine Contrast Media Extravasation

Contrast Media Extravasation

Spain
Lao-Oxford-Mahosot Hospital Wellcome Trust Research...
Mahidol Oxford Tropical Medicine Research Unit

Not yet recruiting

Rickettsia Clearance Study (RiCS)

Infectious Disease | Therapeutics

Lao People's Democratic Republic
Centro Hospitalar do Porto

Completed

Propofol Pharmacokinetics and Pharmacodynamics Modelling

Intravenous Anesthetic Agent Overdose

Portugal
King Hussein Cancer Center

Withdrawn

Radiation Oncology Mobile Application (γ-App)

Head and Neck Cancer | Radiation Toxicity

Jordan
Vanderbilt University Medical Center
National Institute of General Medical Sciences (NIGMS)

Completed

Pharmacogenomics of the Variability in the In Vivo Response to Glucocorticoids

Glucose Intolerance | Glucocorticoids Toxicity

United States
University Hospital, Geneva

Unknown

APAP Hepatotoxicity After Therapeutic Doses

Malnutrition | Paracetamol Toxicity | Hepatotoxicity

Switzerland
RWTH Aachen University
Technion, Israel Institute of Technology

Unknown

Optimized Multi-modality Machine Learning Approach During Cardio-toxic Chemotherapy to Predict Arising Heart Failure (MERMAID)

Toxicity Due to Chemotherapy

Germany
ivWatch, LLC

Completed

Monitoring the Peripheral Intravenous Infusion Site for Infiltration and Extravasation

Extravasation of Diagnostic and Therapeutic Materials | Extravasation | Infiltration | IV Infiltration | IV Extravasation

United States
Mayo Clinic

Completed

Satellite-supplementation of Medical Outreach Clinics: a Feasibility Study

Telemedicine | Primary Health Care | Diagnosis | Therapeutics | Developing Countries

Honduras

Clinical Trials on Therapeutic Agent Toxicity

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Spain

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Rare Diseases

Drug Interventions

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