Clinical Trials on Thoracic Surgery, Lung Isolation in United Kingdom

Total 4542 results

Northwestern University
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Cerebral Autoregulation Monitoring During Cardiac Surgery

Cardiopulmonary Bypass | Thoracic Surgery

United States
University of Kansas Medical Center

Completed

Comparison of Apnea Tolerance in Two Positions of Patients With BMI 30-40

General Surgery

United States
Institute of Cancer Research, United Kingdom

Unknown

Combination Chemotherapy With or Without Surgery and Radiation Therapy in Treating Patients With Mesothelioma That Can Be Removed By Surgery

Malignant Mesothelioma

United Kingdom
University of Kansas Medical Center

Completed

Evaluation of Apnea Tolerance in Bariatric Patients Following Rapid-sequence Induction of Anesthesia

General Surgery

United States
European Organisation for Research and Treatment...
ETOP IBCSG Partners Foundation

Completed

SPECTAlung: Screening Patients With Thoracic Tumors for Efficient Clinical Trial Access (SPECTAlung)

Any Stage of Lung Cancer (Any Histotype) | Any Stage of Malignant Pleural Mesothelioma | Any Stage of Any Thymic Malignancy

Spain, Belgium, Ireland, Slovenia, France, United Kingdom, Poland, Italy, Switzerland
European Organisation for Research and Treatment...

Completed

Pemetrexed Disodium and Cisplatin Followed By Surgery and Radiation Therapy in Treating Patients With Malignant Pleural Mesothelioma

Malignant Mesothelioma

Belgium, Italy, Netherlands, United Kingdom
Hoffmann-La Roche

Completed

A Study to Assess the Incidence of EGFR Mutation in Patients With Newly Diagnosed Locally Advanced or Metastatic Non-Small Cell Lung Cancer in the UK, And of Tarceva (Erlotinib) as First-Line Therapy in EGFR Mutation Positive Patients.

Non-Squamous Non-Small Cell Lung Cancer

United Kingdom
European Organisation for Research and Treatment...

Completed

Docetaxel and Cisplatin in Treating Patients With Untreated Stage IIIA Non-small Cell Lung Cancer

Lung Cancer

Poland, United Kingdom, Netherlands, Italy, Germany
Achilles Therapeutics UK Limited

Recruiting

ATL001 in Patients With Advanced Unresectable or Metastatic NSCLC

Advanced Non Small Cell Lung Cancer

United States, Spain, Germany, France, United Kingdom
University of Oxford
Beckton Dickinson

Recruiting

Prospective Data Collection on Clinical, Radiological and Patient Reported Outcomes After Pleural Intervention (PROSPECT)

Pneumothorax | Pleural Diseases | Pleural Neoplasms | Pleural Effusion, Malignant | Pleural Effusion | Procedural Complication | Pleural Infection | Pleural Mesothelioma | Complications, Pulmonary | Pleural Metastases

United Kingdom
Mayo Clinic

Recruiting

Thoracic Specimen Registry

Lung Cancer | Thoracic Diseases | Lung Transplant

United States
ETOP IBCSG Partners Foundation
Spanish Lung Cancer Group

Completed

BELIEF (Bevacizumab and ErLotinib In EGFR Mut+ NSCLC) (BELIEF)

Lung Cancer

Spain, Ireland, United Kingdom, Switzerland, France, Germany, Greece, Italy
Hoffmann-La Roche

Completed

A Study to Assess Programmed Death Ligand-1 (PD-L1) Expression in Cytological Versus Histological Lung Cancer Specimens

Carcinoma, Non-Small-Cell Lung | Carcinoma, Small Cell

United Kingdom, Czechia, Germany, Poland, Spain, Switzerland
AstraZeneca

Completed

Study to Determine the Effect of Food on the Blood Levels of AZD9291 Following Oral Dosing of a Tablet Formulation in Patients With Non-Small Cell Lung Cancer

Advanced Non Small Cell Lung Cancer | Advanced (Inoperable) Non Small Cell Lung Cancer

France, Korea, Republic of, United Kingdom, Spain
Adaptimmune

Completed

MAGE A10ᶜ⁷⁹⁶T for Advanced NSCLC

Carcinoma | Non-Small Cell Lung Cancer

United States, Spain, United Kingdom, Canada
Yale University

Completed

Changes in Fitness and Strength in Postoperative Cardiac Patients Undergoing Exercise Therapy: Biological and Functional Mechanisms of Recovery

Cardiorespiratory; Insufficiency, Due to A Procedure, Long-Term, Cardiac Surgery

United States
Celgene

Completed

Study of Amrubicin With or Without Cisplatin Versus Etoposide-cisplatin for Extensive Stage Small Cell Lung Cancer

Small Cell Lung Cancer

Belgium, United Kingdom, Netherlands, Italy, Poland
Bristol-Myers Squibb

Terminated

Trial of Dasatinib in Patients With Advanced Cancers Harboring DDR2 Mutation or Inactivating B-RAF Mutation

Carcinoma, Non-small Cell Lung

Brazil, Taiwan, United Kingdom, United States, Canada, Germany, Poland
AstraZeneca

Completed

Study to Assess the Effect of Itraconazole (a CYP3A4 Inhibitor) on the Pharmacokinetics of AZD9291, in Patients With EGFR Positive Non-small Cell Lung Cancer. Patients Will be Chosen From Those Who Have Already Been Prescribed an EGFR TKI Medicine (Such as Iressa or Tarceva)

Advanced Non Small Cell Lung Cancer | Advanced (Inoperable) Non Small Cell Lung Cancer

Belgium, United States, Korea, Republic of, Taiwan, United Kingdom, Netherlands
Papworth Hospital NHS Foundation Trust
London School of Hygiene and Tropical Medicine; King's College London; University... and other collaborators

Completed

MesoTRAP: A Study Comparing Video-assisted Thoracoscopic Partial Pleurectomy/Decortication With Indwelling Pleural Catheter in Patients With Trapped Lung Due to Malignant Pleural Mesothelioma. (MesoTRAP)

Malignant Pleural Mesothelioma | Trapped Lung

United Kingdom
Bristol-Myers Squibb

Terminated

Study of BMS-275183 in Patients With Pre-treated Non-small Cell Lung Cancer

Non-small Cell Lung Cancer

Spain, United States, Belgium, France, Italy, Netherlands, United Kingdom
Royal Marsden NHS Foundation Trust

Recruiting

Preventing Viral Pandemic Associated Risk of Cancer Death Using Less Invasive Diagnostic Tests- Liquid Biopsies (PREVAILctDNA)

Biliary Tract Neoplasms | Neoplasm, Bladder | Neoplasm of Lung | Neoplasms Pancreatic | Neoplasm, Colorectal | Gastro Intestinal Stromal Tumour

United Kingdom
Imperial College London
University College, London; Medical Research Council; National Institute for...

Recruiting

A Randomised Open-label Phase III Trial of REduced Frequency Pembrolizumab immuNothErapy for First-line Treatment of Patients With Advanced Non-small Cell Lung Cancer (NSCLC) (REFINE-Lung)

Lung Cancer, Nonsmall Cell

United Kingdom
University of Birmingham
Pfizer; AstraZeneca; Mirati Therapeutics Inc.; Cancer Research UK; Experimental Cancer...

Active, not recruiting

National Lung Matrix Trial: Multi-drug Phase II Trial in Non-Small Cell Lung Cancer

Adenocarcinoma | Carcinoma, Squamous Cell | Non-Small Cell Lung Cancer

United Kingdom
University Hospital Southampton NHS Foundation...
British Lung Foundation; University of Southampton

Active, not recruiting

Niraparib Efficacy in Patient With Unresectable Mesothelioma (NERO)

Mesothelioma, Malignant

United Kingdom
Children's Hospital Medical Center, Cincinnati
The Hospital for Sick Children

Completed

Virtual Parental Presence on Induction (VPPIA)

Anxiety | Surgery

United States, Canada
Eli Lilly and Company

Completed

A Study of Thymidylate Synthase Expression in Patients With Non-Small Cell Lung Cancer

Non-Small Cell Lung Cancer

United Kingdom, Ireland
George Washington University

Recruiting

Erector Spinae Block for Thoracic Surgery

Thoracic Neoplasms | Thoracic Cancer | Thoracic Diseases | Pulmonary Cancer | Pulmonary Neoplasm

United States
BioNTech SE

Recruiting

Clinical Trial Evaluating the Safety, Tolerability and Preliminary Efficacy of BNT116 Alone and in Combinations in Patients With Advanced Non-small Cell Lung Cancer (LuCa-MERIT-1)

Non-Small Cell Lung Cancer

Spain, Germany, Turkey, United States, Hungary, United Kingdom, Poland
ETOP IBCSG Partners Foundation
Mirati Therapeutics Inc.

Recruiting

Adagrasib in Patients With KRASG12C-mutant NSCLC Who Are Elderly or Have Poor Performance Status (ADEPPT)

NSCLC Stage IV | KRAS P.G12C

Ireland, Italy, France, Spain, United Kingdom, Belgium
Cancer Trials Ireland

Completed

Bortezomib in Treating Patients With Malignant Pleural Mesothelioma

Malignant Mesothelioma

United Kingdom, Ireland, Belgium, Netherlands
ETOP IBCSG Partners Foundation
Merck Sharp & Dohme LLC; Frontier Science Foundation, Hellas

Completed

PembROlizuMab Immunotherapy Versus Standard Chemotherapy for Advanced prE-treated Malignant Pleural Mesothelioma (PROMISE-meso)

Pleural Mesothelioma Malignant Advanced

United Kingdom, Switzerland, Spain
Eli Lilly and Company

Withdrawn

A Study of Gemcitabine-Carboplatin Plus Necitumumab (LY3012211) in Chemotherapy-Naïve Participants With Locally Advanced or Metastatic Squamous Non-Small Cell Lung Cancer (NSCLC)

Metastatic Squamous Non-Small Cell Lung Cancer | Locally Advanced Squamous Non-Small Cell Lung Cancer

Italy, Romania, Germany, Belgium, Russian Federation, United States, United Kingdom
M.D. Anderson Cancer Center

Withdrawn

Gabapentin for the Reduction of Opiate Use Following Pulmonary Resection (GROUP Trial)

Pulmonary Disease | Thoracic

United States
University of Wisconsin, Madison

Withdrawn

Validation of a Novel Thoracic Neoplasm Radiotherapy Image Guidance Technique: A Pilot Study

Lung Cancer

United States
Active Biotech AB

Completed

ABR-217620 in Patients With Advanced Non-Small Cell Lung Cancer, Renal Clear Cell Carcinoma or Pancreatic Cancer

Renal Cell Carcinoma | Pancreatic Cancer | Non-Small-Cell Lung Carcinoma

United States, Norway, United Kingdom
AstraZeneca

Completed

Randomized Study Of CP-675,206 or Best Supportive Care Immediately After Platinum-Based Therapy For Non-Small Cell Lung Cancer (NSCLC)

Carcinoma, Non-small-cell Lung

United States, Canada, Korea, Republic of, United Kingdom, Czech Republic
European Organisation for Research and Treatment...

Withdrawn

KRN7000 in Treating Patients With Solid Tumors

Lung Cancer | Unspecified Adult Solid Tumor, Protocol Specific

France, Netherlands, Norway, Belgium, Switzerland, Austria, United Kingdom, Germany, Denmark
University of Washington
National Cancer Institute (NCI)

Completed

Proton Beam Re-Irradiation in Thoracic Cancers

Recurrent Disease | Thoracic Neoplasm | Metastatic Malignant Neoplasm in the Lung

United States
University of Maryland, Baltimore

Recruiting

Bronchial Mapping (GCC 1635)

Thoracic Cancer

United States
ETOP IBCSG Partners Foundation
Janssen Pharmaceuticals

Recruiting

AMAZE-lung: Amivantamab, Lazertinib and Bevacizumab in Patients With EGFR-mutant Advanced Non-small Cell Lung Cancer With Progression on Previous Third-generation EGFR-TKI (AMAZE-lung)

Non Small Cell Lung Cancer

Spain, France, Switzerland, United Kingdom, Singapore, Italy, Netherlands
Epizyme, Inc.

Completed

Study of the EZH2 Inhibitor Tazemetostat in Malignant Mesothelioma

Mesothelioma | BAP1 Loss of Function

United States, United Kingdom, France
Taiho Oncology, Inc.

Recruiting

A Study of TAS3351 in NSCLC Patients With EGFRmt (TAS3351)

Non-Small Cell Lung Cancer

United States, France, Italy, Korea, Republic of, Japan, Spain, Germany, Netherlands, United Kingdom
Ribon Therapeutics, Inc.

Active, not recruiting

RBN-2397 in Combination With Pembrolizumab in Patients With SCCL

Advanced Squamous Non-Small Cell Lung Carcinoma

United Kingdom, United States, Israel, Spain
University of Pittsburgh

Completed

Long Term Patency Following Arterial Repair

Upper Extremity Arterial Surgery

United States
AbbVie

Recruiting

A Study to Assess Prevalence of a Specific Protein Overexpression in Adult Participants With Non-Small Cell Lung Cancer (METRIX)

Non Small Cell Lung Cancer

Canada, United Kingdom, Argentina, Japan, Switzerland
The New York Proton Center

Recruiting

Patient-Generated Health Data Collection During Chemoradiotherapy for Lung Cancer (PGHD)

Thoracic Cancer

United States
Aultman Health Foundation
GlaxoSmithKline

Terminated

Weekly Topotecan With Docetaxel in Recurrent Small Cell Lung Cancer

Mediastinal Neoplasms

United States
ETOP IBCSG Partners Foundation
Biodesix, Inc.

Completed

Testing of Drugs Erlotinib and Docetaxel in Lung Cancer Patients Classified Regarding Their Outlook Using VeriStrat®. (EMPHASIS)

Carcinoma, Non-Small-Cell Lung

Ireland, Switzerland, Denmark, Spain, United Kingdom, Belgium, Hungary, Greece, Israel, Austria, Italy, Netherlands
Sanofi

Completed

Evaluation of the Overall Survival of Meclinertant Versus Placebo After a First Line Chemotherapy With Cisplatin + Etoposide (SESAME)

Small Cell Lung Cancer | Lung Cancer | Pulmonary Neoplasms

France, Brazil, Poland, Russian Federation, Australia, Germany, Italy, Spain, Belgium, Mexico, Argentina, Hungary, United Kingdom, Netherlands

Clinical Trials on Thoracic Surgery, Lung Isolation in United Kingdom

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