Clinical Trials on Thrombotic Thrombocytopenic Purpura

Total 3909 results

Hutchison Medipharma Limited

Active, not recruiting

Phase III Study on HMPL-523 for Treatment of ITP

Primary Immune Thrombocytopenia (ITP)

China
Institute of Hematology & Blood Diseases Hospital
Henan Cancer Hospital; Nantong University; Tianjin Medical University Second... and other collaborators

Unknown

Eltrombopag Combining Rituximab Versus Eltrombopag in the Management of Primary Immune Thrombocytopenia (ITP) in Adults

Primary Immune Thrombocytopenia (ITP)

China
920th Hospital of Joint Logistics Support Force...

Recruiting

Efficacy and Safety of CAR-T Cells Therepy for Chronic or Refractory Primary Immune Thrombocytopenia (ITP)

ITP - Immune Thrombocytopenia

China
Assiut University

Recruiting

Explore the Relationship Between Platelet Count and Bleeding Score in ITP

ITP - Immune Thrombocytopenia

Egypt
Institute of Hematology & Blood Diseases Hospital...
Henan Cancer Hospital; Beijing Children's Hospital; Tianjin Medical University... and other collaborators

Recruiting

Longitudinal Cohort of Pediatric Primary Immune Thrombocytopenia (ITP)

Primary Immune Thrombocytopenia

China
Seoul National University Hospital

Recruiting

The Investigate Efficacy and Safety Evaluation of Bortezomib in Patients With Relapsed/Refractory Immune Thrombocytopenia

Relapsed/Refractory Immune Thrombocytopenia

Korea, Republic of
Biopharma Plasma LLC

Recruiting

Intravenous Immunoglobulin (IVIG, Bioven) Efficacy and Safety in Chronic Primary Immune Thrombocytopenia (ITP) in Adults

Primary Immune Thrombocytopenia

Ukraine
Assistance Publique - Hôpitaux de Paris
GlaxoSmithKline

Recruiting

Efficacy and Safety of Subcutaneous Belimumab or Placebo in Addition of Rituximab in Persistent or Chronic Immune Thrombocytopenia (RITUX-PLUS 2)

Primary Immune Thrombocytopenia (ITP)

France
Fundación Pública Andaluza para la gestión de la...

Recruiting

Romiplostim Plus Dexamethasone vs Dexamethasone in Patients With Newly Diagnosed Primary Immune Thrombocytopenia (RODEX)

Primary Immune Thrombocytopenia

Spain
Assistance Publique - Hôpitaux de Paris

Recruiting

IgIV Plus Prednisone vs High-dose Dexamethasone for ITP (IVIORDEX)

Immune Thrombocytopenia (ITP)

France
argenx

Recruiting

A Phase 3 Study to Evaluate the Safety and Efficacy of Efgartigimod PH20 Subcutaneous in Adult Patients With Primary Immune Thrombocytopenia (ADVANCE SC+)

Primary Immune Thrombocytopenia

United States, Australia, Bulgaria, China, Georgia, Greece, Italy, Japan, Poland, Portugal, Romania, Russian Federation, Thailand, Turkey, Argentina, Chile, Ireland, Jordan, Tunisia, Korea, Republic of, Mexico, New Zealand, South Africa and more
argenx

Completed

A Study to Assess the Efficacy and Safety of Efgartigimod in Adult Patients With Primary Immune Thrombocytopenia (ITP). (ADVANCE)

Primary Immune Thrombocytopenia

United States, Austria, Belgium, Bulgaria, Czechia, France, Georgia, Germany, Hungary, Italy, Japan, Netherlands, Poland, Russian Federation, Spain, Turkey, Ukraine, United Kingdom
UCB Biopharma SRL

Terminated

A Study to Investigate the Long-term Safety, Tolerability, and Efficacy of Rozanolixizumab in Study Participants With Persistent or Chronic Primary Immune Thrombocytopenia (ITP) (myOpportunITy3)

Primary Immune Thrombocytopenia

United States, China, Georgia, Germany, Hungary, Italy, Japan, Moldova, Republic of, Poland, Russian Federation, Spain, Taiwan, Ukraine, United Kingdom
Novartis Pharmaceuticals

Completed

A Study to Assess Efficacy and Safety of Eltrombopag in Combination With a Short Course of Dexamethasone in Patients With Newly Diagnosed ITP (XPAG-ITP)

Immune Thrombocytopenia (ITP)

Germany
Takeda

Active, not recruiting

A Study of TAK-079 in Adults With Persistent/Chronic Primary Immune Thrombocytopenia

Primary Immune Thrombocytopenia

Spain, United States, Croatia, Italy, China, Germany, Bulgaria, Greece, Slovenia, Japan, Ukraine
Fundación Pública Andaluza para la gestión de la...

Completed

Andalusian Experience in the Use of Fostamatinib in Patients With ITP. FOSTASUR Study

Primary Immune Thrombocytopenia

Spain
UCB Biopharma SRL

Terminated

A Study to Evaluate the Efficacy, Safety, and Tolerability of Rozanolixizumab in Adult Study Participants With Persistent or Chronic Primary Immune Thrombocytopenia (ITP) (myOpportunITy1)

Primary Immune Thrombocytopenia

United States, Bulgaria, France, Georgia, Greece, Hungary, Italy, Japan, Korea, Republic of, Moldova, Republic of, Poland, Romania, Russian Federation, Taiwan, Ukraine, United Kingdom
Hospital Civil de Guadalajara

Completed

Evaluation of the Effect in Platelet Count of Atorvastatin and N-acetyl Cysteine

Primary Immune Thrombocytopenia

Mexico
Gruppo Italiano Malattie EMatologiche dell'Adulto

Completed

Eltrombopag in Second Line Adult Primary Immune Thrombosytopenia

Primacy Immune Thrombocytopenia

Italy
Assiut University

Unknown

Effect of DNMT SNPs on DNA Methylation in Primary ITP

Primary Immune Thrombocytopenia
Shenyang Sunshine Pharmaceutical Co., LTD.

Completed

Evaluating the Efficacy and Safety of Different Human Thrombopoietin (rhTPO) Regimens in the Treatment of Patients With Primary Immune Thrombocytopenia (ITP)

ITP

China
Shandong University
West China Hospital; Jinan Military General Hospital; Shandong University of... and other collaborators

Completed

Autoantibody Specificity and Response to IVIG in ITP

Immune Thrombocytopenia (ITP)

China
Hadassah Medical Organization

Terminated

The Role of Traditional Chinese Medicine in the Treatment of Chronic Childhood Immune Thrombocytopenia (ITP)

Childhood Chronic Immune Thrombocytopenia

Israel
Ostfold Hospital Trust
Oslo University Hospital; South-Eastern Regional Health Authority

Completed

Rituximab as Second Line Treatment for ITP

Immune Thrombocytopenia (ITP)

Norway
Rigel Pharmaceuticals

Completed

Pilot Study of Fostamatinib Disodium/R935788 for the Treatment of Adult Refractory Immune Thrombocytopenic Purpura (ITP)

Purpura, Thrombocytopenic, Idiopathic

United States
Jiangsu HengRui Medicine Co., Ltd.

Unknown

A Study of Hetrombopag Olamine in Chronic Idiopathic Thrombocytopenic Purpura (ITP) Patients

Purpura, Thrombocytopenic, Idiopathic

China
Peking University People's Hospital
Peking University First Hospital; Beijing Friendship Hospital; Chinese PLA General... and other collaborators

Recruiting

The Combination of Teriflunomide and Danazol for Steroid-resistant/Relapse Immune Thrombocytopenia

Immune Thrombocytopenia

China
Peking University People's Hospital
Peking University First Hospital; Beijing Friendship Hospital; Chinese PLA General... and other collaborators

Recruiting

Low-dose Baricitinib Plus High-dose Dexamethasone for Patients With Newly Diagnosed Immune Thrombocytopenia

Immune Thrombocytopenia

China
Peking University People's Hospital
Peking University First Hospital; Beijing Friendship Hospital; Chinese PLA General... and other collaborators

Recruiting

Low-dose Baricitinib Plus Danazol for Steroid-resistant/Relapse Immune Thrombocytopenia

Immune Thrombocytopenia

China
Jiangsu HengRui Medicine Co., Ltd.

Not yet recruiting

Extension Study of Herombopag for Pediatric Patients With Chronic Immune Thrombocytopenia

Immune Thrombocytopenia
Peking University People's Hospital

Not yet recruiting

The Combination of Terbutaline and Danazol as the Treatment of Corticosteroid-resistant/Relapse Immune Thrombocytopenia

Immune Thrombocytopenia
Peking University People's Hospital

Not yet recruiting

Combined Steroid and Cyclosporin as First-line Treatment in Adults With Primary Immune Thrombocytopenia

Immune Thrombocytopenia

China
Jena University Hospital
Novartis; Amgen; Grifols Biologicals, LLC; argenx; Swedish Orphan Biovitrum; University...

Recruiting

ITP Registry and Accompanying Biospecimen Collection (ITP-Registry)

Immune Thrombocytopenia

Germany
Shandong University

Recruiting

A Multicenter Randomized Open-label Study of Diammonium Glycyrrhizinate Enteric-coated Capsule Plus DXM Versus DXM in Treatment of ITP

Immune Thrombocytopenia

China
Jiangsu HengRui Medicine Co., Ltd.

Recruiting

Hetrombopag for Pediatric Patients With Chronic Immune Thrombocytopenia

Immune Thrombocytopenia

China
Shandong University

Recruiting

Glycyrrhetinic Acid Combined With Dexamethasone in Management of Newly Diagnosed ITP

Immune Thrombocytopenia

China
Centre Hospitalier Universitaire Dijon

Recruiting

Role of Fcgamma Receptors in Immune Thrombocytopenia (ITP) (PTI Fc)

Immune Thrombocytopenia

France
Bioverativ, a Sanofi company

Completed

A Study to Assess Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Multiple- Dose BIVV009 in Participants With Chronic Immune Thrombocytopenia (ITP)

Purpura, Thrombocytopenic, Idiopathic

United Kingdom, United States, Germany
Amgen

Completed

Long-term Study of Romiplostim in Thrombocytopenic Pediatric Patients With Immune Thrombocytopenia (ITP)

Immune Thrombocytopenia

United States, Canada, Belgium, Czechia, Mexico, Turkey, Australia, Spain, France, Israel, Hungary, South Africa, Poland, Russian Federation, United Kingdom, Brazil, Switzerland
Unity Health Toronto
University of Toronto; Li Ka Shing Knowledge Institute

Unknown

Proof-of-Concept: A Pilot, Randomized, Double-Blind Study of Oseltamivir Versus Placebo for Immune Thrombocytopenia

Immune Thrombocytopenia

Canada
Shandong University

Unknown

Connection Between Vitamin D Level and the Efficacy of Dexamethasone in Immune Thrombocytopenia

Immune Thrombocytopenia
Biotest
Syneos Health

Completed

This Clinical Study is to Test Efficacy and Safety of BT595 in Chronic Primary Immune Thrombocytopenia (ITP)

Immune Thrombocytopenia

Bulgaria, Czechia, Germany, Hungary, Serbia, Spain
Weill Medical College of Cornell University
GlaxoSmithKline

Completed

Eltrombopag and the Bcl-extra-large (xL) Pathway in Idiopathic Thrombocytopenic Purpura (ITP)

Immune Thrombocytopenia

United States
Gruppo Italiano Malattie EMatologiche dell'Adulto

Unknown

Response Rate and Duration After Discontinuation Thrombopoietin Receptor Agonists Primary Immune Thrombocytopenia

Immune Thrombocytopenia

Italy
Shandong University
Cancer Institute and Hospital, Chinese Academy of Medical Sciences; Shandong... and other collaborators

Unknown

Decitabine Combining Dexamethasone Versus Dexamethasone in Management of ITP

Purpura, Thrombocytopenic, Idiopathic | Immune Thrombocytopenia

China
Weill Medical College of Cornell University
Novartis

Terminated

End of EXTEND: Discontinuation of Medication for Patients With Immune Thrombocytopenia

Immune Thrombocytopenia

United States
Assiut University

Completed

Reposition of Second Line Treatment in Chronic Immune Thrombocytopenia

Immune Thrombocytopenia

Egypt
Shandong University
Peking University People's Hospital; The Affiliated Hospital of Qingdao University and other collaborators

Unknown

Recombinant Human Thrombopoietin(rhTPO) in Pregnancy With Immune Thrombocytopenia

Immune Thrombocytopenia

China
Assistance Publique - Hôpitaux de Paris

Completed

Polymorphism and Auto-reactive B and T Cells Subsets in Adult's Immune Thrombocytopenia (ITP) (Poly-ITP)

Immune Thrombocytopenia

France
Stanford University
Weill Medical College of Cornell University

Completed

Genome-Wide Gene Expression Profiling of Patients With ITP Receiving Thrombopoietin Mimetics

Immune Thrombocytopenia

United States

Clinical Trials on Thrombotic Thrombocytopenic Purpura

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