Clinical Trials on Tissue and Organ Donation

Total 107692 results

Christopher Dvorak

No longer available

Expanded Access Protocol (EAP) Using the CliniMACS® Device for Pediatric Haplocompatible Donor Stem Cell Transplant

Acute Myeloid Leukemia | Leukocyte Disorders | Acute Lymphoblastic Leukemia | Chronic Myeloid Leukemia | Myelodysplastic Syndrome | Cytopenias | Immune Deficiency | Lymphomas | Bone Marrow Failure | Osteopetrosis | Hemoglobinopathy | Anemia Due to Intrinsic Red Cell Abnormality

United States
University Health Network, Toronto

Unknown

Diagnosing Frontotemporal Lobar Degeneration

Progressive Supranuclear Palsy | Semantic Dementia | Corticobasal Syndrome | Progressive Nonfluent Aphasia | Behavioral Variant Frontotemporal Dementia | Amyotrophic Lateral Sclerosis and/or Frontotemporal Dementia

Canada
Ohio State University Comprehensive Cancer Center

Completed

Single Incision Laparoscopic Surgery in Treating Patients With Colorectal Disease

Crohn Disease | Familial Adenomatous Polyposis | Stage IIIA Colon Cancer | Stage IIIB Colon Cancer | Stage IIIC Colon Cancer | Recurrent Colon Cancer | Stage I Colon Cancer | Stage IIA Colon Cancer | Stage IIB Colon Cancer | Stage IIC Colon Cancer | Adenomatous Polyp | Hereditary Intestinal Polyposis Syndrome

United States
Exonhit

Completed

Performance of AclarusDx™, a Blood-Based Transcriptomic Test for AD, in US Patients Newly Referred to a Memory Center

Mild Cognitive Impairment | Primary Progressive Aphasia | Vascular Dementia | Alzheimer's Disease | Mixed Dementia | Fronto-temporal Dementia | Parkinson' Disease Dementia

United States
UNC Lineberger Comprehensive Cancer Center

Recruiting

Registry for Adults With Plasma Cell Disorders (PCD's)

Multiple Myeloma | Amyloidosis | Smoldering Multiple Myeloma | Plasma Cell Leukemia | Cryoglobulinemia | Light Chain Deposition Disease | Castleman's Disease | Heavy Chain Deposition Disease | Polyneuropathy Organomegaly Endocrinopathy Monoclonal Gammopathy and Skin Changes

United States
Jordi Gol i Gurina Foundation

Not yet recruiting

Extraordinarily Fun Training Project in Compulsory Secondary Education - Sexually Transmitted Infections (FEDE-ITS)

Gonorrhea | Chlamydia Infections | Human Immunodeficiency Virus (HIV) | Human Papillomavirus (HPV) | Syphilis Infection | Gender Equity

Spain
University of Chicago

Recruiting

Detecting HPV DNA in Anal and Cervical Cancers

Cervical Cancer | Anal Cancer | HPV-Related Carcinoma | HPV-Related Cervical Carcinoma | Uterine Cervical Cancer | HPV-Related Anal Squamous Cell Carcinoma

United States
National Cancer Institute (NCI)
Canadian Cancer Trials Group

Active, not recruiting

Testing Cabozantinib, Crizotinib, Savolitinib and Sunitinib in Kidney Cancer Which Has Progressed

Unresectable Renal Cell Carcinoma | Stage III Renal Cell Cancer AJCC v7 | Stage IV Renal Cell Cancer AJCC v7 | Type 1 Papillary Renal Cell Carcinoma | Type 2 Papillary Renal Cell Carcinoma | Metastatic Papillary Renal Cell Carcinoma | Locally Advanced Papillary Renal Cell Carcinoma

United States, Canada
AIDS Malignancy Consortium
National Cancer Institute (NCI)

Completed

Anal HPV Tests in Screening for Cell Changes in the Anus in Patients With HIV

HIV Infection | Anal Cancer | Human Papilloma Virus Infection

United States, Puerto Rico
University Medical Centre Ljubljana

Unknown

Changes in Haemostasis After Therapeutic Plasmapheresis With Citrate Anticoagulation

Guillain-Barre Syndrome | Humoral Rejection | CIDP | Miller Fisher Syndrome | Good Pasture Syndrome | Hyperviscosity Syndrome

Slovenia
PETHEMA Foundation

Completed

LINFOTARGAM: Treatment With Chemotherapy Plus Rituximab and Highly Active Antiretroviral Therapy in Patients With Diffuse Large B Cell Lymphoma and Infection With the Human Immunodeficiency Virus (HIV) (LINFOTARGAM)

HIV Infections | Diffuse Large B Cell Lymphoma

Spain
Louisiana State University Health Sciences Center...
Merck Sharp & Dohme LLC

Recruiting

Immunogenicity of Gardasil-9 HPV Vaccine in People Living With HIV (AGO-Gard)

Cervical Intraepithelial Neoplasia | Human Immunodeficiency Virus | Anal Intraepithelial Neoplasia | Papillomavirus Infection | Papillomavirus Vaccines | Serology | Oral Cavity Infection

United States
Ciprian Catana, MD, PhD
National Cancer Institute (NCI)

Recruiting

Multimodal Machine Learning Characterization of Solid Tumors

Glioma | Hepatocellular Carcinoma (HCC) | Prostate Cancer | Adenocarcinoma of Prostate | Renal Cell Carcinoma (RCC) | Radical Prostatectomy

United States
ANRS, Emerging Infectious Diseases
University Hospital, Geneva; University of Bordeaux; International Agency for... and other collaborators

Recruiting

Evaluation of Triage Options After HPV Testing for Cervical Cancer Screening Among HIV-infected Women (AIMA-CC)

HIV Infections | HPV - Anogenital Human Papilloma Virus Infection

Burkina Faso, Cambodia, Côte D'Ivoire
M.D. Anderson Cancer Center
National Cancer Institute (NCI); Exelixis

Active, not recruiting

Cabozantinib or Sunitinib Malate in Treating Participants With Metastatic Variant Histology Renal Cell Carcinoma

Renal Cell Carcinoma | Metastatic Renal Cell Carcinoma | Stage IV Renal Cell Cancer AJCC v8 | Sarcomatoid Renal Cell Carcinoma | Chromophobe Renal Cell Carcinoma | Papillary Renal Cell Carcinoma | Malignant Neoplasms of Urinary Tract | Renal Cell Carcinoma Associated With Xp11.2 Translocations/TFE3... and other conditions

United States
University of California, San Diego

Withdrawn

Non-Invasive Cervical Cancer Radiotherapy for Stage IB-IVB (NICER)

Cervical Cancer | Cervical Cancer Stage | Cervical Cancer Stage IB2 | Cervical Cancer Stage IB1 | Cervical Cancer Stage I | Cervical Cancer Stage IB | Cervical Cancer Stage II | Cervical Cancer Stage IIa | Cervical Cancer, Stage IIB | Cervical Cancer, Stage III | Cervical Cancer Stage IIIB | Cervical Cancer... and other conditions

United States
National Cancer Institute (NCI)

Active, not recruiting

Veliparib and Irinotecan Hydrochloride in Treating Patients With Cancer That Is Metastatic or Cannot Be Removed by Surgery

Hodgkin Lymphoma | Non-Hodgkin Lymphoma | Advanced Malignant Solid Neoplasm | Stage III Pancreatic Cancer AJCC v6 and v7 | Stage IV Pancreatic Cancer AJCC v6 and v7 | Metastatic Malignant Solid Neoplasm | Triple-Negative Breast Carcinoma | Unresectable Solid Neoplasm | Metastatic Malignant Neoplasm | Unresectable... and other conditions

United States
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Not yet recruiting

Testing Laser Therapy for Treatment of Vaginal Dryness in Survivors of Breast Cancer, The Revitalize Trial

Anatomic Stage I Breast Cancer AJCC v8 | Anatomic Stage IA Breast Cancer AJCC v8 | Anatomic Stage IB Breast Cancer AJCC v8 | Anatomic Stage II Breast Cancer AJCC v8 | Anatomic Stage IIA Breast Cancer AJCC v8 | Anatomic Stage IIB Breast Cancer AJCC v8 | Anatomic Stage III Breast Cancer AJCC v8 | Anatomic... and other conditions
Roswell Park Cancer Institute
National Cancer Institute (NCI); Cianna Medical, Inc.

Terminated

Radiation Therapy in Treating Post-Menopausal Women With Early Stage Breast Cancer Undergoing Surgery

Stage I Breast Cancer | Stage II Breast Cancer | Stage IIIA Breast Cancer | Stage IIIC Breast Cancer | Lobular Breast Carcinoma In Situ | Estrogen Receptor Negative | Estrogen Receptor Positive | HER2/Neu Negative | Progesterone Receptor Positive | Ductal Breast Carcinoma In Situ | Mucinous Breast Carcinoma | Tubular Breast Carcinoma and other conditions

United States
Marc Dall'Era, MD
National Cancer Institute (NCI); Janssen, LP

Recruiting

Niraparib Before Surgery in Treating Patients With High Risk Localized Prostate Cancer and DNA Damage Response Defects

BRCA1 Gene Mutation | BRCA2 Gene Mutation | Prostate Carcinoma | RAD51C Gene Mutation | BRIP1 Gene Mutation | ATM Gene Mutation | CHEK2 Gene Mutation | NBN Gene Mutation | RAD51 Gene Mutation | CDK12 Gene Mutation | CHEK1 Gene Mutation | DNA Damage Response Gene Mutation | DNA Repair Gene Mutation | FANCA Gene Mutation and other conditions

United States
Sun Yat-sen University
Huizhou No.1 Maternal and Child Care Service Cencer

Completed

No-worry Baby Project

Depression | Immune System Diseases | Obesity | Asthma | Obstetric Labor Complications | Neurodevelopmental Disorders | Gestational Diabetes Mellitus in Pregnancy | Gestational Hypertension | Allergic Disorder | Anemia in Pregnancy | Reproductive Disorder | Complications, Pregnancy | Thyroid Disease Pregnancy

China
Massachusetts General Hospital
Genzyme, a Sanofi Company; Scott and White Hospital & Clinic

Terminated

Kidney Information Network for Disease Research and Education (KINDRED)

Kidney Diseases | Genetic Diseases, X-Linked | End Stage Renal Disease | ESRD | Fabry Disease | Rare Diseases

United States
University of California, San Francisco

Completed

Pupillary Unrest in Ambient Light, and Relationship to Opioid-Induced Respiratory Depression

Acute Pain | Safety Issues | Respiratory Depression | Overdose of Opiate | Opioid; Intoxication, Perception Disturbance (Acute)

United States
Tubulis GmbH

Recruiting

FiH Study to Investigate Safety, PK and Efficacy of the NaPi2b ADC TUB-040 in Patients With PROC or r/r Adenocarcinoma NSCLC (NAPISTAR1-01)

Ovarian Cancer | Non-small Cell Lung Cancer

United States
The Affiliated Hospital of Qingdao University

Recruiting

The Efficacy and Safety of Chinese Domestic Surgical Robot System in Urological Telesurgery

Renal Cell Carcinoma | Prostate Cancer | Bladder Cancer | Ureteral Calculi | Renal Calculi | Penile Cancer | Pelvic Tumor | Adrenal Tumor | Nonfunctioning Kidney | Renal Cyst | Ureteropelvic Junction Obstruction | Renal Pelvis Carcinoma | Ureteral Tumor | Duplex Kidney

China
National Cancer Institute (NCI)
NRG Oncology

Recruiting

Testing the Addition of the AKT Inhibitor, Ipatasertib, to Treatment With the Hormonal Agent Megestrol Acetate for Recurrent or Metastatic Endometrial Cancers

Recurrent Endometrial Endometrioid Adenocarcinoma | Stage IV Uterine Corpus Cancer AJCC v8 | FIGO Grade 1 Endometrial Endometrioid Adenocarcinoma | FIGO Grade 2 Endometrial Endometrioid Adenocarcinoma | Metastatic Endometrial Endometrioid Adenocarcinoma

United States
Vilnius University
Kaunas University of Technology

Recruiting

Triggers and Risk Factors for Recurrence of Atrial Arrhythmias With the Use of Long-term Monitoring (TriggersAF)

Alcohol Drinking | Sleep Disorder | Stress | Atrial Fibrillation | Sleep Apnea | Atrial Flutter | Arterial Hypertension | Physical Inactivity | Atrial Tachycardia | Atrial Arrhythmia | Caffeine Dependence | Premature Atrial Contractions | Overexertion

Lithuania
Mucpharm Pty Ltd
St George Hospital, Australia

Not yet recruiting

Safety of Nebulized Combination Therapy BromAc® in COVID-19 Respiratory Disease

COVID-19 | Ventilator Associated Pneumonia | COVID-19 Pneumonia | COVID-19 Acute Respiratory Distress Syndrome
Mayo Clinic

Recruiting

Leveraging Methylated DNA Markers (MDMs) in the Detection of Endometrial Cancer, Ovarian Cancer, and Cervical Cancer (ECHO)

Cervical Cancer | Ovarian Cancer | Atypical Endometrial Hyperplasia | Endometrial Cancer | Cervical Dysplasia | Adnexal Mass

United States
Xencor, Inc.
ICON plc

Recruiting

A Study of XmAb20717 (Vudalimab)in Patients With Selected Advanced Gynecologic and Genitourinary Malignancies

Ovarian Cancer | Endometrial Cancer | Cervical Carcinoma | Metastatic Castration-Resistant Prostate Cancer (mCRPC) | Clear Cell Carcinoma

United States
Hospital Universitario Ramon y Cajal

Recruiting

Pulmonary Inflammation in COVID-19 ARDS (IMPU-COVID)

COVID-19 Acute Respiratory Distress Syndrome | ARDS Due to Disease Caused by Severe Acute Respiratory Syndrome Coronavirus 2

Spain
Massachusetts General Hospital

Recruiting

Kisspeptin Administration in the Adult

PCOS | Kallmann Syndrome | Hypogonadotropic Hypogonadism | Polycystic Ovarian Syndrome | Hyperprolactinemia | GnRH Deficiency

United States
University of California, San Francisco

Completed

Study of Thiotepa and TEPA Drug Exposure in Pediatric Hematopoietic Stem Cell Transplant Patients

Sickle Cell Disease | Hemoglobinopathies | Fanconi Anemia | Thalassemia | Hematologic Malignancies | Immune Deficiency | Nonmalignant Diseases | Genetic Inborn Errors of Metabolism

United States
zr Pharma & GmbH
Foundation Medicine; Myriad Genetics, Inc.

Completed

A Study of Rucaparib in Patients With Platinum-Sensitive, Relapsed, High-Grade Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cancer (ARIEL2) (ARIEL2)

Ovarian Cancer | Fallopian Tube Cancer | Epithelial Ovarian Cancer | Peritoneal Cancer

United States, Spain, Canada, Australia, United Kingdom, France
Albert Einstein College of Medicine
National Cancer Institute (NCI)

Completed

Palliative Care in Improving Quality of Life in Patients With High Risk Primary or Recurrent Gynecologic Malignancies

Peritoneal Neoplasms | Recurrent Ovarian Carcinoma | Recurrent Uterine Corpus Carcinoma | Cervical Carcinoma | Ovarian Carcinoma | Recurrent Cervical Carcinoma | Uterine Corpus Cancer | Vulvar Carcinoma | Primary Peritoneal Carcinoma | Recurrent Vulvar Carcinoma

United States
Gynecologic Oncology Group
National Cancer Institute (NCI)

Completed

EGEN-001 and Pegylated Liposomal Doxorubicin Hydrochloride in Treating Patients With Recurrent or Persistent Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cancer

Recurrent Fallopian Tube Carcinoma | Recurrent Ovarian Carcinoma | Recurrent Primary Peritoneal Carcinoma | Ovarian Clear Cell Cystadenocarcinoma | Ovarian Endometrioid Adenocarcinoma | Ovarian Seromucinous Carcinoma | Ovarian Serous Cystadenocarcinoma | Ovarian Undifferentiated Carcinoma

United States
University College, London

Unknown

Pubertal Induction in Individuals With Hypogonadism

Hypopituitarism | Primary Ovarian Insufficiency | Turner's Syndrome | Hypogonadotrophic Hypogonadism | Primary Amenorrhoea | Hypothalamic Amenorrhoea

United Kingdom
University of Aarhus

Unknown

Prospective Characterization of the Heart, Aorta and Blood Pressure in Turner Syndrome. Association With Aortic Dissection. (TSCORII)

Hypertension | Ischemic Heart Disease | Aortic Aneurysm | Turner Syndrome | Congenital Heart Defect

Denmark
University Hospital, Basel, Switzerland
Bristol-Myers Squibb; Swiss National Science Foundation

Completed

Cardiovascular Risk Factor Management in HIV Infection

HIV Infection | Dyslipidemia | Coronary Heart Disease | Diabetes Mellitus, Non-Insulin-Dependent

Switzerland
Novo Nordisk A/S

Completed

Safety and Efficacy of Long-term Somatropin Treatment in Children (GrowthWIN II)

Turner Syndrome | Growth Hormone Disorder | Growth Hormone Deficiency in Children | Genetic Disorder | Foetal Growth Problem | Small for Gestational Age | Growth Disorder | Idiopathic Short Stature

Germany
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI)

Completed

Suberoylanilide Hydroxamic Acid in Treating Patients With Advanced Solid Tumors That Have Not Responded to Previous Therapy

Lymphoma | Leukemia | Small Intestine Cancer | Prostate Cancer | Unspecified Adult Solid Tumor, Protocol Specific | Multiple Myeloma and Plasma Cell Neoplasm

United States
National Cancer Institute (NCI)

Recruiting

A Study Combining the Peposertib (M3814) Pill With Standard Chemotherapy in Patients With Ovarian Cancer With an Expansion in High Grade Serous Ovarian Cancer and Low Grade Serous Ovarian Cancer

Recurrent Fallopian Tube Carcinoma | Recurrent Ovarian Carcinoma | Recurrent Primary Peritoneal Carcinoma | Ovarian Seromucinous Carcinoma | Ovarian Undifferentiated Carcinoma | Fallopian Tube Transitional Cell Carcinoma | Primary Peritoneal High Grade Serous Adenocarcinoma | Fallopian Tube Clear... and other conditions

United States
Fondazione Policlinico Universitario Agostino Gemelli...

Recruiting

Gestional Trophoblastic Neoplasia Ultrasound Assessment: Titanium Study (TITANIUM)

Describe Typical Gray Scale/Color Doppler Ultrasound Features of Gestational Trophoblastic Neoplasia at the US Examination | To Assess if There Are Differences at the Baseline US Scan Between Low-risk and High-risk Patients | To Identify Ultrasound Predictors of Resistance to First-line... and other conditions

Italy
Princess Anna Mazowiecka Hospital, Warsaw, Poland
Medical University of Warsaw

Not yet recruiting

The High Initial Dose of Monitored Vitamin D Supplementation in Preterm Infants. (HIDVID)

Nephrolithiasis | Vitamin D Deficiency | Metabolic Bone Disease | Osteopenia of Prematurity | Late-Onset Neonatal Sepsis

Poland
Sun Yat-sen University

Not yet recruiting

First-line Maintenance Treatment With Fluzoparib Plus Bevacizumab in Advanced BRCA Wild Type Ovarian Cancer

Ovarian Cancer | Primary Peritoneal Cancer | High Grade Serous Adenocarcinoma of Ovary | High Grade Endometrioid Ovarian Cancer | Fallopian-tube Cancer

China
University College, London
Barts & The London NHS Trust; Anticancer Fund, Belgium; JP Moulton Charitable...

Recruiting

Adaptive ChemoTherapy for Ovarian Cancer in Patients With Replased Platinum-sensitive High Grade Serous or High Grade Endometrioid Ovarian Cancer (ACTOv)

Ovarian Cancer | Fallopian Tube Cancer | Relapsed Ovarian Cancer | Peritoneal Cancer | High Grade Serous Carcinoma | Ovary Cancer | Endometrioid Carcinoma

United Kingdom
National Research Centre, Egypt
Egyptian Military Medical Services

Not yet recruiting

Clinical Assessment of Oral Lactoferrin as a Safe Antiviral and Immunoregulatory in Treating COVID-19 Disease (COVID-19_LF)

COVID-19 | Coronavirus Infection | SARS-CoV 2 | Acute Respiratory Distress Syndrome | Corona Virus Infection | Middle East Respiratory Syndrome (MERS)

Egypt
Compugen Ltd

Recruiting

COM902 (A TIGIT Inhibitor) in Subjects With Advanced Malignancies

Multiple Myeloma | Ovarian Cancer | Lung Cancer | Advanced Cancer | Colon Cancer | Plasma Cell Neoplasm | HNSCC | Microsatellite Stable Colorectal Carcinoma | MSS-CRC

United States
Regeneron Pharmaceuticals

Recruiting

Study of REGN4018 Administered Alone or in Combination With Cemiplimab in Adult Patients With Recurrent Ovarian Cancer or Other Recurrent Mucin-16 Expressing (MUC16+) Cancers

Recurrent Endometrial Cancer | Recurrent Ovarian Cancer | Recurrent Fallopian Tube Cancer | Recurrent Primary Peritoneal Cancer

United States, Spain, Korea, Republic of, Italy, United Kingdom, Netherlands, Belgium, Australia, France, Israel
University of Alberta
Canadian Institutes of Health Research (CIHR)

Active, not recruiting

Evidence Based Mental Wellness Programming Online for Adults Across Chronic Physical Conditions (EMPOwer)

Heart Failure | Cancer | Chronic Kidney Diseases | Cirrhosis, Liver | Primary Biliary Cholangitis | Digestive Diseases | Women Who Have Experienced a Cardiac Event | Post-Transplant | Other Chronic Physical Condition

Canada

Clinical Trials on Tissue and Organ Donation

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