Clinical Trials on Tobacco Use in Canada

Total 203 results

St. Justine's Hospital

Active, not recruiting

A Brief Digital Screening Tool to Address Tobacco and E-cigarette Use in Pediatric Medical Care (CanCEASE)

Tobacco Cessation | Tobacco Use | Smoking, Tobacco | Second Hand Tobacco Smoke | Vaping

Canada
Women's College Hospital

Recruiting

Screening While You Wait 2: Alcohol and Tobacco Use (SWYW2)

Alcohol; Harmful Use | Tobacco Use | Tobacco Use Cessation | Alcohol Use, Unspecified

Canada
Philip Morris Products S.A.

Active, not recruiting

Pharmacokinetics and Comparative Bioavailability of Nicotine From Two Variants of NP2, NP2-4mg and NP2-6mg, Compared to Nicotine Lozenge 4mg (Loz-4mg) and Nicotine Gum 4mg (Gum-4mg)

Tobacco Use

Canada
Lawson Health Research Institute
University of Western Ontario, Canada

Completed

Effect of a Perioperative Smoking Cessation Program on Smoking Cessation/Reduction and Perioperative Complications

Smoking | Tobacco Use

Canada
Centre for Addiction and Mental Health

Completed

Targeting Mailed Nicotine Patch Distribution Interventions to Rural Regions of Canada

Tobacco Use Cessation

Canada
Centre for Addiction and Mental Health

Completed

Offering Nicotine Patches to All Households in a Municipality With High Smoking Rates

Tobacco Use Cessation

Canada
Centre for Addiction and Mental Health

Completed

Exploring Occupancy of Dopamine D3 Receptor by Buspirone in Humans Using PET

Smoking Cessation | Tobacco Use Cessation

Canada
Sanofi

Completed

Efficacy and Safety of Dianicline Treatment as an Aid to Smoking Cessation in Cigarette Smokers (AMERIDIAN)

Smoking Cessation | Tobacco Use Cessation

United States, Canada
Centre for Addiction and Mental Health
Canadian Cancer Society (CCS)

Recruiting

Smoking Cessation and Menstrual Cycle Phase (MC-NRT)

Smoking Cessation | Tobacco Smoking | Substance Use Disorders | Nicotine Dependence | Nicotine Use Disorder

Canada
Centre for Addiction and Mental Health

Completed

Using Non-invasive Brain Stimulation (tDCS) With Varenicline for Treating Tobacco Dependence

Smoking Cessation | Tobacco Smoking | Tobacco Use Disorder | Substance Use Disorders | Molecular Mechanisms of Pharmacological Action | Tobacco Dependence | Physiological Effects of Drugs

Canada
Ottawa Hospital Research Institute
Operation Come Home

Active, not recruiting

Tobacco-Concurrent Addictions in At-Risk Youth in Ottawa (TCAY-Ottawa)

Tobacco Use | Substance Use

Canada
University of British Columbia
Provincial Health Services Authority

Withdrawn

Tobacco Retraining of Automatic Approach to Treat Individuals With Tobacco Dependence and Severe Concurrent Disorders.

Tobacco Retraining of Automatic Approach | Placebo Task

Canada
Ottawa Hospital Research Institute

Unknown

E-Cigarette Inner City RCT

Substance Use | Mental Illness | Tobacco Dependence | COPD Asthma

Canada
Centre for Addiction and Mental Health
Canadian Institutes of Health Research (CIHR)

Completed

Use of Pharmacotherapy to Reduce Cue-responsiveness in Smokers

Nicotine Dependence | Tobacco Dependence

Canada
University of British Columbia
Vancouver Coastal Health Research Institute

Completed

Emergency Department Smoking Cessation Study

Tobacco Use Cessation

Canada
Centre for Addiction and Mental Health
Canadian Institutes of Health Research (CIHR)

Completed

Effect of Varenicline on Reactivity to Smoking and Drinking Cues

Alcohol Dependence | Tobacco Dependence

Canada
Marco Leyton

Active, not recruiting

Investigation of Cigarette Cravings in Smokers

Tobacco Use | Addiction Nicotine | Cigarette Smoking

Canada
Laval University

Unknown

Combining Noninvasive Brain Stimulation and Cognitive Training on Tobacco Craving

Tobacco Use Disorder

Canada
Centre for Addiction and Mental Health

Recruiting

Cytisine for Smoking Cessation

Smoking Cessation | Tobacco Use Disorder | Alcohol Use Disorder

Canada
Centre for Addiction and Mental Health
Pfizer

Completed

Smoking-induced Dopamine Release: a [11C]-(+)-PHNO PET Study in Humans

Tobacco Use Disorder

Canada
Laval University

Unknown

Effects of Non-invasive Brain Stimulation in Tobacco Use Disorder

Tobacco Use Disorder

Canada
Centre for Addiction and Mental Health

Completed

Smoking While on Transdermal Nicotine Replacement Therapy: Effects on Craving and Cessation

Nicotine Dependence

Canada
Centre for Addiction and Mental Health

Completed

Initial Screening of Gemfibrozil as a Novel Treatment for Tobacco Addiction

Nicotine Dependence

Canada
Centre for Addiction and Mental Health
Pfizer; Ontario Lung Association

Completed

The Effect of Varenicline on D2/D3 Receptor Binding in Smokers

Nicotine Dependence

Canada
Centre for Addiction and Mental Health
Ontario Lung Association

Terminated

Prazosin for Smoking Cessation

Nicotine Dependence

Canada
Centre for Addiction and Mental Health
Pfizer; Brainsway

Completed

Deep rTMS and Varenicline for Smoking Cessation

Smoking Cessation | Tobacco Use Disorder

Canada
Centre for Addiction and Mental Health

Completed

Nicotine Metabolizers and [11C]-(+)-PHNO (MET)

Nicotine Dependence

Canada
Centre for Addiction and Mental Health
Nuraleve, Inc.

Withdrawn

Transcranial Direct Current Stimulation in a Smoking Cessation Trial (tDCS)

Nicotine Dependence

Canada
Centre for Addiction and Mental Health
Ottawa Heart Institute Research Corporation; Canadian Cancer Society (CCS)

Completed

Personalized Dosing of Nicotine Replacement (NRT to Effect)

Tobacco Use Disorder | Nicotine Dependence

Canada
Centre for Addiction and Mental Health

Terminated

Efficacy and Neural Correlates of Personalized Treatment With Transdermal Nicotine Replacement (iT-NRT)

Tobacco Use Disorder | Nicotine Dependence

Canada
Centre for Addiction and Mental Health
Global Research Awards for Nicotine Dependence (GRAND)

Completed

The MATCH (Medication Aids for Tobacco Cessation and Health) Study (MATCH)

Tobacco Use Disorder | Nicotine Dependence

Canada
Centre for Addiction and Mental Health
Canadian Tobacco Control Research Initiative

Terminated

Baclofen for Smoking Cessation in a Non-Psychiatric Population (Baclofen)

Nicotine Dependence

Canada
Centre for Addiction and Mental Health
Canadian Tobacco Control Research Initiative

Terminated

Testing a Full Substitution Therapy Approach As Treatment of Tobacco Dependence

Nicotine Dependence

Canada
Centre for Addiction and Mental Health
Ontario Ministry of Health and Long Term Care

Completed

Distribution of Bupropion and Varenicline to Increase Smoking Cessation Attempts

Smoking | Smoking Cessation | Tobacco Use Disorder

Canada
Centre for Addiction and Mental Health

Completed

A Dietary Supplement for Early Cigarette Withdrawal (CIGAR)

Nicotine Dependence, Cigarettes, With Withdrawal

Canada
Centre for Addiction and Mental Health

Completed

Electronic Cigarettes in Daily Dependent Smokers

Nicotine Dependence | Substance Withdrawal Syndrome

Canada
Centre for Addiction and Mental Health
Canadian Institutes of Health Research (CIHR); Canadian Tobacco Control Research...

Completed

Study of Varenicline (Champix) for Smoking Cessation/Reduction in Patients With Bipolar Disorder

Nicotine Dependence

Canada
Centre for Addiction and Mental Health
Canadian Institutes of Health Research (CIHR)

Completed

Effects of rTMS on Cigarette Smoking and Cognition in Schizophrenia (rTMSsmokelab)

Schizophrenia | Nicotine Addiction

Canada
British Columbia Cancer Agency
National Cancer Institute (NCI); University of Cincinnati

Terminated

Green Tea Extract in Treating Current or Former Smokers With Bronchial Dysplasia

Tobacco Use Disorder | Lung Cancer | Precancerous Condition

Canada
University of Pennsylvania
National Institute on Drug Abuse (NIDA)

Completed

Pharmacogenetics of Nicotine Addiction Treatment

Nicotine Addiction

United States, Canada
Ottawa Heart Institute Research Corporation
Canadian Institutes of Health Research (CIHR)

Active, not recruiting

The INITIATE Study: Initiating Nicotine Dependence Treatment for Smokers Admitted to Emergency Departments (INITIATE)

Nicotine Dependence, Cigarettes | Nicotine Withdrawal

Canada
Ottawa Hospital Research Institute

Recruiting

A Healthy People Initiative: Building the Socio-Economic Capital of Low Income Population At-Risk for HIV and Hepatitis-C

Substance Use Disorders | Nicotine Dependence

Canada
Juul Labs, Inc.
Inflamax Research Incorporated

Completed

Study to Evaluate Constituents in Exhaled Breath and Room Air From Use of E-vapor Products and Conventional Cigarettes

Second Hand Tobacco Smoke

Canada
Centre for Addiction and Mental Health
Canadian Psychiatric Research Foundation

Completed

Neural Inhibition as a Mechanism of Nicotine Dependence Among Persons With Schizophrenia

Smoking | Schizophrenia | Schizoaffective Disorder | Psychosis | Nicotine Dependence | Schizophreniform Disorders

Canada
British Columbia Cancer Agency
National Cancer Institute (NCI); University of Cincinnati

Completed

Green Tea Extract in Preventing Cancer in Former and Current Heavy Smokers With Abnormal Sputum

Tobacco Use Disorder | Lung Cancer

Canada
Centre for Addiction and Mental Health
Ontario Ministry of Health and Long Term Care

Completed

STOP Study: Effectiveness of Zyban in a Clinical Population

Smoking Cessation | Cigarette Smoking | Nicotine Addiction

Canada
University Health Network, Toronto
Ontario Ministry of Health and Long Term Care

Completed

Surgical Patient Knowledge and Safe Use of Opioids

Opioid Use

Canada
University Health Network, Toronto

Completed

Improving Surgical Patient Knowledge and Safe Use of Opioids

Opioid Use

Canada
Hamilton Health Sciences Corporation
McMaster University

Terminated

Perioperative Pregabalin for Reducing Opioid Consumption After Cardiac Surgery (OPIATE)

Opioid Use

Canada
Masimo Corporation

Terminated

Feasibility and Acceptability of Oxygen Saturation Monitoring Using Masimo SafetyNet Alert (MSNA) in a Supportive Housing Program

Opioid Use

Canada

Clinical Trials on Tobacco Use in Canada

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Romania

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Rare Diseases

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