Clinical Trials on Toe Deformity

Total 12386 results

DePuy International

Terminated

A Single Centre Study to Assess the Long-term Performance of the DePuy ASR™ System in Primary Hip Resurfacing Surgery

Osteoarthritis | Rheumatoid Arthritis | Avascular Necrosis | Post-traumatic Arthritis | Congenital Hip Dysplasia | Slipped Capital Femoral Epiphysis | Collagen Disorders | Nonunion of Femoral Fractures

South Africa
DePuy International

Completed

A Study to Assess the Long-term Performance of SmartSet® HV and SmartSet® GHV Bone Cements in Primary Total Hip Replacement

Osteoarthritis | Rheumatoid Arthritis | Avascular Necrosis | Post-traumatic Arthritis | Congenital Hip Dysplasia | Slipped Capital Femoral Epiphysis | Collagen Disorders | Traumatic Femoral Fractures | Nonunion of Femoral Fractures

Slovakia
DePuy International

Terminated

A Single Centre Study to Assess the Long-term Performance of the Pinnacle™ Cup With a Ceramic-on-ceramic Bearing in Primary Total Hip Replacement

Osteoarthritis | Rheumatoid Arthritis | Avascular Necrosis | Post-traumatic Arthritis | Congenital Hip Dysplasia | Slipped Capital Femoral Epiphysis | Collagen Disorders | Traumatic Femoral Fractures | Nonunion of Femoral Fractures

Czech Republic
DePuy International

Terminated

A Two Centre Study to Assess the Long-term Performance of the Pinnacle™ Cup With a Metal-on-Metal Bearing in Primary Total Hip Replacement

Osteoarthritis | Rheumatoid Arthritis | Avascular Necrosis | Post-traumatic Arthritis | Congenital Hip Dysplasia | Slipped Capital Femoral Epiphysis | Collagen Disorders | Traumatic Femoral Fractures | Nonunion of Femoral Fractures

United Kingdom, Italy
DePuy International

Terminated

A Multi-centre Study to Assess the Long-term Performance of the Summit™ Hip in Primary Total Hip Replacement

Osteoarthritis | Rheumatoid Arthritis | Avascular Necrosis | Post-traumatic Arthritis | Congenital Hip Dysplasia | Slipped Capital Femoral Epiphysis | Collagen Disorders | Traumatic Femoral Fractures | Nonunion of Femoral Fractures

China, Hong Kong, Italy, Korea, Republic of, New Zealand
60P Australia Pty Ltd

Not yet recruiting

A Clinical Evaluation of the Safety and Efficacy of Randomized Placebo Versus the 8-aminoquinoline Tafenoquine for Early Symptom Resolution in Patients With Mild to Moderate COVID 19 Disease and Low Risk of Disease Progression

Infectious Disease | SARS-CoV-2 | Severe Acute Respiratory Syndrome Coronavirus 2 | COVID 19 Disease | Mild to Moderate COVID 19 Disease
Inmunotek S.L.
LAT Research; Xolomon Tree S.L.

Not yet recruiting

Clinical Trial to Evaluate the Efficacy and Safety of Polymerized, Mannan-Conjugated Dermatophagoides Allergen Extract (MM09-SLIM)

Allergic Rhinitis | Allergic Asthma | Allergic Rhinoconjunctivitis | Allergy to House Dust Mite

Argentina
University of Miami

Recruiting

Database of Monochorionic Pregnancies

Twin to Twin Transfusion Syndrome | Twin; Complicating Pregnancy | Twin Reversal Arterial Perfusion Syndrome | Monochorionic Diamniotic Placenta | Monochorial Monoamniotic Placenta

United States
Maaynei Hayesha Medical Center

Recruiting

COVID 19 ANTOBODIES IN PREGNANT WOMEN AND THEIR CONNECTION TO BETA CELL FUNCTION IN THE FETUS

Generation of Anti COVID-19 Antibodies in a Fetus, Whose Mother Was Exposed to COVID or Was Vaccinated During Pregnancy

Israel
King's College Hospital NHS Trust
University of Pennsylvania; Gilead Sciences; The Leeds Teaching Hospitals NHS... and other collaborators

Active, not recruiting

Genetic Determinants of Kidney Disease in People of African Ancestry With HIV (GEN-AFRICA)

Cardiovascular Diseases | Kidney Diseases | Obesity | Diabetes Mellitus | Genetic Predisposition to Disease | Kidney Injury | HIV Nephropathy

United Kingdom
Autolus Limited

Enrolling by invitation

Long-term Follow-up of Patients Treated With Autologous T Cells Genetically Modified

Multiple Myeloma | DLBCL | T Cell Lymphoma | Patients Followed for up to 15 Years Following Their First Dose of AUTO CAR T Cell Therapy | ALL, Adult and Pediatric

United Kingdom
Lysovant

Withdrawn

ERAdicate S. Aureus in Patients With Bacteremia and Endocarditis (ERASE)

Endocarditis Infective | Bacteremia Due to Staphylococcus Aureus | Left Sided Infective Endocarditis (Disorder) | Right Sided Infective Endocarditis (Disorder)

United States
Universitaire Ziekenhuizen KU Leuven

Active, not recruiting

Mediators in Nasal Hyperreactivity in Allergic Rhinitis and Chronic Rhinosinusitis

Chronic Rhinosinusitis With Nasal Polyps | Hyperactivity | Allergic Rhinitis Due to House Dust Mite

Belgium
Ocuwize LTD

Completed

Evaluate the Efficacy and Safety of LO2A Eye Drops for Symptomatic Improvement of Dry Eye in Patients With Sjögren's Syndrome

Dry Eye Due to Sjögren's Syndrome

Israel
American Regent, Inc.

Completed

Treatment Response of Injectafer vs Oral Iron to Baseline Hepcidin Levels in Patients With Iron Deficiency Anemia (IDA) Secondary to Inflammatory Bowel Disease (IBD) or Gastric Bypass

Iron Deficiency Anemia Secondary to IBD or Gastric Bypass
Beijing Tsinghua Chang Gung Hospital
Chinese Medical Doctor Association; Institute for precision medicine of Tsinghua... and other collaborators

Completed

Efficacy of a Self-test and Self-alert Mobile Applet in Detecting Susceptible Infection of COVID-19 (COVID-19)

Susceptibility to Viral and Mycobacterial Infection

China
AstraZeneca
ISTITUTO REGINA ELENA - CENTRO RICERCHE SPERIMENTALI

Terminated

ZD4054 (Zibotentan) or Placebo Plus Chemotherapy in Patients With Advanced Ovarian Cancer

Patients With Advanced Ovarian Cancer Sensitive to Platinum-based Chemotherapy

Italy, Germany
OMNI Medical Services, LLC
OMNI Medical Services Inc

Recruiting

Outcomes Mandate National Integration With Cannabis as Medicine (OMNI-Can)

Depression | COVID-19 | Epilepsy | Multiple Sclerosis | Glaucoma | Cancer | Covid19 | Chronic Pain | Parkinson Disease | Inflammatory Bowel Diseases | Hepatitis C | Insomnia | HIV/AIDS | Amyotrophic Lateral Sclerosis | Fibromyalgia | Anxiety | Bipolar Disorder | Seizures | Crohn Disease | Traumatic Brain Injury | Ulcerative Colitis | Sickle... and other conditions

United States
Columbia University
International Agency for Research on Cancer

Recruiting

InterNatIonal CHildhood Leukemia Microbiome/MEtabolome Cohort (NICHE)

Acute Lymphoblastic Leukemia | Nutrition Aspect of Cancer | Genetic Predisposition | Microtia

United States, Guatemala, Brazil, Honduras, India, Tanzania
Hospital Clinic of Barcelona
Fundació La Marató de TV3

Unknown

Perifoveal Vascular Network Assessed by OCT-Angiography in Type I Diabetes Mellitus

Diabetes Mellitus | Diabetes Mellitus, Type 1 | Diabetic Retinopathy | Retinal Vascular | Retinal Disease | Retinal Ischemia | Retinal Ischaemia Due to Type 1 Diabetes Mellitus | Vessels; Retina, Tortuous

Spain
Actavis Inc.
Watson Laboratories, Inc.

Completed

A Multi-center, Double-blind, Randomized Study, Comparing Clindamycin Phosphate Vaginal Cream 2% (Watson Laboratories, Inc.) to Clindesse® (Ther-Rx™, Clindamyin Phosphate Vaginal Cream 2%) and Both Active Treatments to a Placebo Control in the Treatment of Bacterial Vaginosis in Non-pregnant Women

BACTERIAL VAGINOSIS | Signs and Symptoms to be Evaluated and Recorded Include | Vaginal Discharge Color, Odor, and Consistency | Vulvovaginal Itching and Irritation (Subjective) Absent, Mild, Moderate, or Severe | Vulvovaginal Inflammation (Objective) Absent, Mild, Moderate, or Severe

United States, Dominican Republic, Puerto Rico
National Institute of Allergy and Infectious Diseases...

Terminated

Biochemical Response to Interferon-Gamma in Subjects With Specific Gene Mutation in Chronic Granulomatous Disease

IFN-Gamma Therapy | CGD Gene Mutation | CGD Response to IFNg | CGD - Chronic Granulomatous Disease | Immunodeficiency Disease

United States
Pontificia Universidad Catolica de Chile

Completed

Topical 10 % Nifedipine Versus 5% Sildenafil in Secondary Raynaud

Lupus Erythematosus, Systemic | Dermatomyositis | Ultrasound Therapy; Complications | Raynaud Disease | Raynaud Phenomenon Due to Trauma | System; Sclerosis

Chile
Georgetown University
Solstice Neurosciences

Completed

Myobloc Atrophy Study (MAS)

Stroke | Brain Injury | Tumor | Spinal Cord Injury (SCI) | Spasticity Secondary to Either a Disorder or Trauma

United States
National Institute of Allergy and Infectious Diseases...

Terminated

Treatment for Growth Failure in Patients With X-Linked Severe Combined Immunodeficiency: Phase 2 Study of Insulin-Like Growth Factor-1

Growth Failure | X-linked Severe Combined Immunodeficiency (XSCID) | Growth Hormone Resistence

United States
Shanghai Changzheng Hospital
First Affiliated Hospital of Zhejiang University; The First Affiliated Hospital... and other collaborators

Unknown

Duration and Adverse Events of Non-cuffed Catheter in Patients With Hemodialysis (DACAPO)

Venous Thrombosis | Central Venous Catheter Thrombosis | Renal Failure Chronic Requiring Hemodialysis | Venous Stenosis | Central Venous Catheterization | Inadequate Hemodialysis Blood Flow | Infection Due to Central Venous Catheter
Pomeranian Medical University Szczecin

Not yet recruiting

Early-initiated High Flow Oxygen Therapy vs Conventional Oxygen Therapy Among Patients With ARDS in the Course of SARS-CoV2 Pneumonia.

Oxygen Deficiency | Corona Virus Infection | ARDS Due to Disease Caused by Severe Acute Respiratory Syndrome Coronavirus 2

Poland
Children's Hospital Medical Center, Cincinnati

Not yet recruiting

Use of NGAL for Fluid Dosing and CRRT Initiation in Pediatric and Neonatal AKI (Taking Focus 2)

Acute Kidney Injury | Acute Kidney Injury Due to Sepsis | Neonatal Sepsis

United States
Yu-Hsiang Wu
Vanderbilt University Medical Center; National Institute on Deafness and Other...

Recruiting

Hearing Aid and Individuals With Cognitive Disorders

Alzheimer Disease 2 Due to Apoe4 Isoform | Presbycusis, Bilateral

United States
University of Nebraska
National Cancer Institute (NCI); VA Nebraska Western Iowa Health Care System; Virginia Mason Hospital/Medical Center

Recruiting

Blood Markers of Early Pancreas Cancer

Diabetes Mellitus, Type 2 | PreDiabetes | Genetic Predisposition to Disease | Chronic Pancreatitis | Inherited Disease | Pancreas Cyst

United States
H. Lee Moffitt Cancer Center and Research Institute
Bristol-Myers Squibb

Active, not recruiting

Pilot Study of Nivolumab w/Ipilimumab or Relatlimab in Surgically Resectable Melanoma Brain Metastases

Metastatic Melanoma | Metastasis to Brain

United States
Pfizer
Arena is a wholly owned subsidiary of Pfizer

Terminated

A Study to Assess the Effect of Oral Temanogrel on Digital Blood Flow in Adult Participants With Raynaud's Phenomenon Secondary to Systemic Sclerosis

Raynaud's Phenomenon Secondary to Systemic Sclerosis

United Kingdom, United States
Heidelberg Engineering GmbH

Completed

Repeatability of Static & Dynamic Composite Confocal Microscopy for Assessment of the Corneal Nerve Fiber Plexus in Early Diabetic Polyneuropathy

Normal Eyes of Subjects Without Diabetes Mellitus | Subjects With Diabetes Mellitus Type 2 Without Coexisting DPN | Subjects With Diabetes Mellitus Type 2 With Coexisting Early to Moderate DPN
Taipei Veterans General Hospital, Taiwan

Unknown

Entecavir for Biological Agents Associated HBV Reactivation in Inflammatory Arthritis Patients

Rheumatoid Arthritis | Exposure to Hepatitis B Virus | Hepatitis B Reactivation

Taiwan
Duke University
David Grant U.S. Air Force Medical Center

Completed

Genetic Risk and Health Coaching for Type 2 Diabetes and Coronary Heart Disease

Prediabetic State | Coronary Heart Disease, Susceptibility to, 5

United States
Norwegian School of Sport Sciences
National Dairy Council

Completed

The Health of Competitive Fitness Athletes

Depression | Exercise Addiction | Perfectionism | Binge Eating | Body Image | Eating Disorder | Resting Metabolic Rate | Dietary Deficiency | Bone Mineral Density, Low, Susceptibility to | Exercise-Related Amenorrhea | Dietary Amenorrhea

Norway
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Neurobehavioral Complications in Children Who Were Previously Treated With Steroids and Intrathecal Therapy for Acute Lymphoblastic Leukemia

Leukemia | Neurotoxicity | Long-term Effects Secondary to Cancer Therapy in Children | Psychosocial Effects of Cancer and Its Treatment

United States
Universitätsklinikum Hamburg-Eppendorf

Completed

Study of Repetitive Intestinal Lavage in Patients With EHEC Associated Hemorrhagic Colitis (EHEC-PEG)

Hemolytic Uremic Syndrome | Hemorrhagic Colitis | Intestinal Infectious Disease | Intestinal Infection Due to E. Coli

Germany
University of California, San Francisco
Varian Medical Systems

Recruiting

Radiation Therapy for the Treatment of Metastatic Gastrointestinal Cancers

Stage IV Anal Cancer AJCC v8 | Metastatic Gastroesophageal Junction Adenocarcinoma | Metastatic Colorectal Carcinoma | Stage IV Colorectal Cancer AJCC v8 | Stage IVA Colorectal Cancer AJCC v8 | Stage IVB Colorectal Cancer AJCC v8 | Stage IVC Colorectal Cancer AJCC v8 | Postneoadjuvant Therapy Stage... and other conditions

United States
National Cancer Institute (NCI)

Active, not recruiting

Tipifarnib for the Treatment of Advanced Solid Tumors, Lymphoma, or Histiocytic Disorders With HRAS Gene Alterations, a Pediatric MATCH Treatment Trial

Malignant Solid Neoplasm | Recurrent Melanoma | Recurrent Ependymoma | Recurrent Ewing Sarcoma | Recurrent Hepatoblastoma | Recurrent Langerhans Cell Histiocytosis | Recurrent Malignant Germ Cell Tumor | Recurrent Malignant Glioma | Recurrent Medulloblastoma | Recurrent Neuroblastoma | Recurrent Non-Hodgkin... and other conditions

United States, Puerto Rico
Sanford Health
National Ataxia Foundation; Beyond Batten Disease Foundation; Pitt Hopkins Research... and other collaborators

Recruiting

Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford (CoRDS)

Mitochondrial Diseases | Retinitis Pigmentosa | Myasthenia Gravis | Eosinophilic Gastroenteritis | Multiple System Atrophy | Leiomyosarcoma | Leukodystrophy | Anal Fistula | Spinocerebellar Ataxia Type 3 | Friedreich Ataxia | Kennedy Disease | Lyme Disease | Hemophagocytic Lymphohistiocytosis | Spinocerebellar Ataxia... and other conditions

United States, Australia
Roswell Park Cancer Institute

Recruiting

Genetically Engineered Cells (EGFRt/19-28z/IL-12 CAR T Cells) for the Treatment of Relapsed or Refractory CD19+ Hematologic Malignancies

Recurrent Mantle Cell Lymphoma | Recurrent Diffuse Large B-Cell Lymphoma | Refractory Diffuse Large B-Cell Lymphoma | Refractory Chronic Lymphocytic Leukemia | Refractory Mantle Cell Lymphoma | Recurrent High Grade B-Cell Lymphoma | Recurrent Transformed Follicular Lymphoma to Diffuse Large B-Cell... and other conditions

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

Loncastuximab Tesirine and Mosunetuzumab for the Treatment of Relapsed or Refractory Diffuse Large B-Cell Lymphoma

Recurrent Diffuse Large B-Cell Lymphoma | Recurrent Primary Mediastinal (Thymic) Large B-Cell Lymphoma | Refractory Diffuse Large B-Cell Lymphoma | Refractory Primary Mediastinal (Thymic) Large B-Cell Lymphoma | Recurrent High Grade B-Cell Lymphoma | Refractory High Grade B-Cell Lymphoma | Recurrent... and other conditions

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Image-guided Proton Therapy for the Treatment of Locally Advanced Unresectable Head and Neck Cancer

Stage III Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC v8 | Stage III Hypopharyngeal Carcinoma AJCC v8 | Stage III Laryngeal Cancer AJCC v8 | Stage III Oropharyngeal (p16-Negative) Carcinoma AJCC v8 | Unresectable Head and Neck Squamous Cell Carcinoma | Unresectable Oropharyngeal... and other conditions

United States
National Cancer Institute (NCI)

Terminated

Veliparib, Oxaliplatin, and Capecitabine in Treating Patients With Advanced Solid Tumors

Unspecified Adult Solid Tumor, Protocol Specific | Adenocarcinoma of the Pancreas | Recurrent Pancreatic Cancer | Stage IV Pancreatic Cancer | Stage IV Breast Cancer | Stage IV Ovarian Epithelial Cancer | Stage IV Ovarian Germ Cell Tumor | Stage II Breast Cancer | Stage IIIA Breast Cancer | Stage IIIB... and other conditions

United States
Academic and Community Cancer Research United

Not yet recruiting

Epcoritamab Compared to Observation for Treating B-cell Lymphoma Patients Not in Complete Remission After CD19-directed CAR-T Therapy

Primary Mediastinal Large B-Cell Lymphoma | Diffuse Large B-Cell Lymphoma, Not Otherwise Specified | Transformed Indolent B-Cell Non-Hodgkin Lymphoma to Diffuse Large B-Cell Lymphoma

United States
Lovisenberg Diakonale Hospital
University of Bergen

Not yet recruiting

Sucrase-isomaltase Deficiency as a Cause of Irritable Bowel Syndrome

Irritable Bowel Syndrome | Functional Gastrointestinal Disorders | Sucrase Isomaltase Deficiency | Sucrose Intolerance Due to Sucrase-Isomaltase Deficiency | Carbohydrate; Malabsorption
Merz Pharmaceuticals GmbH

Recruiting

Study to Compare the Efficacy and Safety of NT 201 (Botulinum Toxin) With Placebo for the Treatment of Lower Limb Spasticity Caused by Stroke or Traumatic Brain Injury (PATTERN)

Lower Limb or Combined Lower Limb and Upper Limb Spasticity Due to Stroke or Traumatic Brain Injury

United States, Belgium, Czechia, France, Germany, Italy, Poland, Spain, United Kingdom, Australia, Hungary, Norway, Switzerland, Slovakia, Ukraine, Russian Federation
David Bartlett
National Cancer Institute (NCI)

Completed

αDC1 Vaccine + Chemokine Modulatory Regimen (CKM) as Adjuvant Treatment of Peritoneal Surface Malignancies

Peritoneal Carcinomatosis | Malignant Neoplasm of Pancreas Metastatic to Peritoneal Surface | Malignant Peritoneal Mesothelioma

United States
City of Hope Medical Center

Recruiting

Early Detection of Advanced Adenomas and Colorectal Cancer (AACRC)

Colorectal Neoplasms | Colorectal Cancer | Colorectal Disorders | Colorectal Adenocarcinoma | Colorectal Cancer Stage II | Colorectal Cancer Stage III | Colorectal Cancer Stage IV | Colorectal Polyp | Colorectal Neoplasms Malignant | Colorectal Adenomatous Polyp | Colorectal Cancer Stage I | Colorectal Adenoma... and other conditions

United States, Italy, China, Spain, Japan

Clinical Trials on Toe Deformity

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