Clinical Trials on Toxicity

Total 700 results

Universiti Kebangsaan Malaysia Medical Centre

Completed

Saliva Substitute Mouthwash in NPC Survivors With Xerostomia: A Randomized Controlled Trial

Xerostomia, Hyposalivation, Saliva Substitute, Radiation-induced Toxicity, Nasopharyngeal Cancer

Malaysia
Case Comprehensive Cancer Center

Completed

Low-Residue Diet in Treating Diarrhea in Patients Receiving Pelvic Radiation Therapy.

Sarcoma | Cervical Cancer | Diarrhea | Prostate Cancer | Radiation Toxicity

United States
Radiation Therapy Oncology Group
National Cancer Institute (NCI); NRG Oncology

Completed

Image-Guided Radiation Therapy in Treating Patients With Primary Soft Tissue Sarcoma of the Shoulder, Arm, Hip, or Leg

Sarcoma | Lymphedema | Radiation Toxicity | Radiation Fibrosis | Musculoskeletal Complications

United States, Canada
National Cancer Institute (NCI)

Terminated

Combination Chemotherapy Before and After Surgery in Treating Patients With Osteosarcoma

Sarcoma | Cardiac Toxicity

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Combination Chemotherapy With or Without Dexrazoxane in Treating Children With Hodgkin's Disease

Lymphoma | Cardiac Toxicity

United States, Canada, Switzerland
Haiyan Li
Peking University; Food and Drug Administration (FDA); Spaulding Clinical Research... and other collaborators

Unknown

Race Difference Moxifloxacin-induced QT Prolongation Between Healthy Chinese and Caucasian Volunteers

Cardiac Toxicity

United States, China
Pusan National University Hospital

Unknown

Acupuncture for Chemotherapy-induced Peripheral Neuropathy

Lymphoma | Multiple Myeloma | Peripheral Neuropathy | Toxicity Due to Chemotherapy

Korea, Republic of
Cambridge University Hospitals NHS Foundation Trust

Unknown

Combination Chemotherapy With or Without Bevacizumab in Treating Patients With Nonmetastatic Breast Cancer

Breast Cancer | Perioperative/Postoperative Complications | Cardiac Toxicity

United Kingdom
Norwegian School of Sport Sciences
Uppsala University

Recruiting

Effects of Exercise Training in Survivors of Lymphoma (LYMfit)

Cardiovascular Diseases | Lymphoma | Cardiotoxicity | Chemotherapeutic Toxicity | Physical Exercise

Norway, Sweden
Indiana University

Recruiting

Pre-Rehabilitation for Female Patients Undergoing Pelvic Radiotherapy

Sexual Dysfunction | Pelvic Pain | Radiation Toxicity | Dyspareunia

United States
Fondazione IRCCS Ca' Granda, Ospedale Maggiore...

Not yet recruiting

A Big Data Approach to Predict NEOnatal Acute Kidney Injury in Newborns expoSed to nephroTOxic Drugs (NeoAKI STOP) (NeoAKISTOP)

Premature Birth | Acute Kidney Injury | Drug Use | Machine Learning | Newborn Morbidity | Drug Interaction | Drug Toxicity | Drug-Induced Nephropathy

Italy
Anhui Provincial Hospital

Recruiting

Neoadjuvant Chemoradiotherapy Combined With Camrelizumab and Nimotuzumab for Esophageal Squamous Cell Carcinoma

Toxicity, Drug

China
Ass. Prof. Jan Nyman

Recruiting

Study on Proton Radiotherapy of Thymic Malignancies (PROTHYM)

Thymus Neoplasms | Cardiotoxicity | Pulmonary Toxicity

Sweden
Prof Corinne Faivre-Finn
The Leeds Teaching Hospitals NHS Trust; University of Leeds; Manchester University... and other collaborators

Recruiting

Avoiding Cardiac Toxicity in Lung Cancer Patients Treated With Curative-intent Radiotherapy (ACCOLADE)

Lung Cancer

United Kingdom
Abramson Cancer Center at Penn Medicine

Active, not recruiting

Risk-Guided Cardioprotection With Carvedilol in Breast Cancer Patients Treated With Doxorubicin and/or Trastuzumab (CCTGuide Pilot)

Heart Failure | Breast Cancer | Cardiomyopathies | Risk Factor, Cardiovascular | Cardiotoxicity | Toxicity Due to Chemotherapy

United States
University of Nottingham
National Institute for Health Research, United Kingdom; International Stem...

Suspended

Prevalence and Impact on QoL From Ototoxicity in Cancer Survivors

Cancer | Hearing Loss, Sensorineural | Tinnitus, Subjective | Chemotherapeutic Toxicity

United Kingdom
University of California, San Francisco
National Cancer Institute (NCI)

Completed

Effects of Chemotherapy on the Brain in Women With Newly Diagnosed Early-Stage Breast Cancer

Breast Cancer | Fatigue | Neurotoxicity | Cognitive/Functional Effects | Psychosocial Effects of Cancer and Its Treatment | Long-term Effects Secondary to Cancer Therapy in Adults | Chemotherapeutic Agent Toxicity

United States
Children's Oncology Group
National Cancer Institute (NCI); Children's Cancer Group

Completed

Chemotherapy Followed by Radiation Therapy in Treating Young Patients With Newly Diagnosed Hodgkin's Disease

Lymphoma | Cardiac Toxicity

United States, Australia, Canada
Henan Provincial People's Hospital
Merck Sharp & Dohme LLC

Unknown

Compare to the Safety of Efavirenz and Nevirapine in Treating HIV Positive Patients With Mild Baseline Liver Function Test Impairment, and/or Hepatitis B or Hepatitis C Co-infection

HIV Infections | Liver Toxicity | Hepatitis Co-infection
Odense University Hospital

Recruiting

OPC5: Pressurized IntraThoracic Aerosol Chemotherapy (PITAC) in Patients With Malignant Pleural Effusion.

Quality of Life | Pleural Carcinomatosis | Chemotherapy Effect | Pleural Neoplasms | Chemotherapeutic Toxicity | Malignant Pleural Effusion | Pleural Cavity Effusion

Denmark
National University of Ireland, Galway, Ireland
Clinical Research Facility Galway; CORRIB Research Centre for Advanced Imaging...

Recruiting

Understanding CARdiac Events in Breast Cancer (UCARE)

Heart Failure | Breast Cancer | Cardiomyopathies | Cardiotoxicity | Chemotherapeutic Toxicity | Oncology

Ireland
Imperial College London

Recruiting

Video Game Hearing Tests for Remote Monitoring of Ototoxicity (VAROT)

Hearing Loss | Aminoglycoside Toxicity | Video Games | Aminoglycoside-Induced Hearing Loss

United Kingdom
Assiut University

Not yet recruiting

Cardiac Toxicity of Hypo Fractionated Radiotherapy in Left Breast Cancer

Breast Cancer Female
Hospital General de Mexico

Recruiting

Efficacy of the Use of Bortezomib for the Treatment of Relapsed Leukemia or Positive MRD

Acute Lymphoblastic Leukemia, in Relapse | Chemotherapeutic Toxicity | Minimal Residual Disease

Mexico
Fundacion CRIS de Investigación para Vencer el...
BTG International Inc.; BioClever 2005 S.L.; Eurofins ADME, S.L.; NTShub, S.L.

Terminated

Reduction of MTX Levels After Glucarpidase Treatment in DLBCL Patients at Risk of CNS

Diffuse Large B-Cell Lymphoma | Drug Toxicity

Spain
Beth Faiman
National Cancer Institute (NCI)

Terminated

Glutamine in Preventing Peripheral Neuropathy in Patients With Multiple Myeloma Receiving Bortezomib

Multiple Myeloma | Peripheral Neuropathy | Chemotherapeutic Agent Toxicity

United States
Odense University Hospital
University of Southern Denmark

Completed

Cardiac Toxicity in Medical Treatment of Breast Cancer (CaTOB)

Heart Failure | Breast Cancer

Denmark
National Institute of Diabetes and Digestive and...

Completed

Evaluation of Albuminuria HIV-Infected Patients

Proteinuria | Albuminuria | HIV-Associated Focal Segmental Glomerulosclerosis | Renal Tubular Toxicity | HIV-Associated Collapsing Glomerulopathy

United States
Vanderbilt University
National Cancer Institute (NCI)

Completed

Side Effects Involving the Heart in Women With Breast Cancer Receiving Doxorubicin and Trastuzumab (PACE in BC)

Breast Cancer | Cardiac Toxicity | Cardiovascular Complications

United States
Centre Francois Baclesse

Terminated

Early Detection of Cardiac Toxicity of Trastuzumab (Herceptin ®) in Patients Treated for Breast Carcinoma: Value of Magnetic Resonance Imaging (MRTOX)

Cancer, Breast | LV Dysfunction

France
Radiation Therapy Oncology Group
National Cancer Institute (NCI)

Completed

Radiation Therapy With or Without Chemotherapy in Reducing Mouth Dryness in Patients With Nasopharyngeal Cancer

Head and Neck Cancer | Radiation Toxicity | Oral Complications of Radiation Therapy

United States
North Central Cancer Treatment Group
National Cancer Institute (NCI)

Completed

Mometasone Furoate in Preventing Radiation Dermatitis in Patients Undergoing Radiation Therapy to the Breast or Chest Wall for Invasive Breast Cancer or Ductal Carcinoma in Situ

Breast Cancer | Radiation Toxicity | Skin Reactions Secondary to Radiation Therapy | Dermatologic Complications

United States
Sophie JACOB
Institut National de la Santé Et de la Recherche Médicale, France; Institut... and other collaborators

Withdrawn

REBECCA Study (RadiothErapy for BrEast Cancer and CArdiotoxicity) (REBECCA)

Breast Cancer | Toxicity Due to Radiotherapy | Lesion; Cardiac

France
University Hospital, Lille
Institut National de la Santé Et de la Recherche Médicale, France

Completed

Outcome of Patients Treated by iv Rt-PA for Cerebral Ischaemia According to the Ratio Sc-tPA/Tc-tPA (OPHELIE)

Stroke, Acute | Drug Toxicity

France
University College, London
Cancer Research UK

Completed

Methotrexate, Glucarpidase, and Leucovorin in Treating Patients With Newly Diagnosed Primary Central Nervous System Lymphoma

Lymphoma | Mucositis | Neurotoxicity | Chemotherapeutic Agent Toxicity

United Kingdom
Jianxing He

Not yet recruiting

Efficacy and Safety of Perioperative Use of Breztri Aerosphere to Relieve Cough After Lobectomy

Cough | Drug Effect | Lung Cancer, Nonsmall Cell | Perioperative | Drug Toxicity
En Chu Kong Hospital

Active, not recruiting

Evaluation of Colchicine and Nonsteroidal Anti-inflammatory Drug Combination Therapy and Renal Function in Gout Patients

Renal Impairment | Gout | Nonsteroidals (NSAIDs)Toxicity | Colchicine Adverse Reaction
Marilyn Dodd
National Cancer Institute (NCI)

Completed

GM-CSF Mouthwash for Preventing and Treating Mucositis in Patients Undergoing Radiation Therapy for Head and Neck Cancer

Head and Neck Cancer | Radiation Toxicity | Tongue Cancer | Mucositis Oral

United States
University College, London

Recruiting

Focal Therapy for Prostate Cancer Using HIFU (INDEX)

Urinary Incontinence | Prostate Cancer | Male Erectile Disorder | Therapy-related Toxicity

United Kingdom
Sidney Kimmel Comprehensive Cancer Center at Johns...
Avon Foundation

Terminated

Detection and Prevention of Anthracycline-Related Cardiac Toxicity With Concurrent Simvastatin

Breast Cancer | Stage I Breast Cancer | Stage II Breast Cancer | Stage III Breast Cancer

United States
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Completed

MRI in Detecting Heart Damage in Patients With Cancer Receiving Chemotherapy With Exercise Capacity Addendum

Breast Cancer | Malignant Neoplasm | Cardiac Toxicity

United States
Instituto do Cancer do Estado de São Paulo
Servier

Recruiting

Adult Acute Lymphoblastic Leukemia Treated With Pediatric Regimen in Brazil (BRALLA)

Acute Lymphoid Leukemia | Chemotherapeutic Toxicity | Minimal Residual Disease | Gene Abnormality

Brazil
National Institute of Diabetes and Digestive and...

Recruiting

Search for New Methods to Detect Acute Renal Failure

Kidney Failure, Chronic | Healthy Volunteers | Kidney Failure | Kidney Disease | Renal Tubular Toxicity

United States
Jessa Hospital

Completed

Antibiotic Prophylaxis in Transurethral Prostate Resection (TURP) and Transurethral Bladder Tumour Resection (TURB) (Prophylaxis001)

Bladder Cancer | Antibiotic-associated Diarrhea | Antibiotic Resistant Infection | Antibiotic Resistant Strain | Antibiotic Toxicity | Prostate Hyperplasia | Urosepsis

Belgium
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Completed

Changes in Semen or Sperm Caused by Temozolomide in Patients With Newly Diagnosed, Progressive, or Recurrent Primary Malignant Brain Tumors

Infertility | Brain and Central Nervous System Tumors | Chemotherapeutic Agent Toxicity

United States
East and North Hertfordshire NHS Trust
British Acupuncture Council

Unknown

Limiting Chemotherapy Side Effects by Using Moxa

Genital Neoplasms, Female | Breast Neoplasms | Colorectal Neoplasms | Toxicity Due to Chemotherapy

United Kingdom
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Combination Chemotherapy Plus Dexrazoxane in Treating Patients With Newly Diagnosed Nonmetastatic Osteosarcoma

Sarcoma | Cardiac Toxicity

United States, Canada, Netherlands, Puerto Rico, Switzerland, Australia
Prof Gérard WAEBER
Centre Hospitalier Universitaire Vaudois; University of Lausanne; Center for...

Terminated

A Double Blind Randomised Placebo-controlled Trial to Assess the Role of Iron Repletion in Glucose Homeostasis. (DIAFER)

Iron-deficiency | Safety Issues | Metabolic Disorder, Glucose | Iron Toxicity | Glucose Metabolism Disorders (Including Diabetes Mellitus) | Metabolic Side Effects of Drugs

Switzerland
Xijing Hospital

Unknown

Chemotherapy Combined With Whole-body Hyperthermia to Treat Stage IIIB/IV Non Small Cell Lung Cancer (WBH&NSCLC)

Toxicity Due to Chemotherapy | Non-small Cell Lung Cancer Stage IIIB

China
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Completed

Donepezil in Treating Young Patients With Primary Brain Tumors Previously Treated With Radiation Therapy to the Brain

Brain and Central Nervous System Tumors | Neurotoxicity | Radiation Toxicity | Cognitive/Functional Effects | Long-term Effects Secondary to Cancer Therapy in Children | Psychosocial Effects of Cancer and Its Treatment

United States

Clinical Trials on Toxicity

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Turkmenistan

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

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