Clinical Trials on Transplant;Failure,Kidney

Total 22342 results

Arcus Biosciences, Inc.

Recruiting

Study of AB598 Monotherapy and Combination Therapy in Participants With Advanced Cancers (ARC-25)

Cervical Cancer | Gastric Cancer | Esophageal Cancer | Ovarian Cancer | Bladder Cancer | Advanced Cancer | Non-Small Cell Lung Cancer (NSCLC) | Advanced Malignancies | Renal Cell Carcinoma (RCC) | Triple Negative Breast Cancer (TNBC) | Head and Neck Squamous Cell Carcinoma (HNSCC) | Gastroesophageal-junction...

United States, Australia
Rahul Aggarwal
AstraZeneca

Recruiting

Ceralasertib (AZD6738) Alone and in Combination With Olaparib or Durvalumab in Patients With Solid Tumors

Clear Cell Renal Cell Carcinoma | Metastatic Renal Cell Carcinoma | Endometrial Cancer | Stage III Renal Cell Cancer | Locally Advanced Malignant Solid Neoplasm | Stage III Pancreatic Cancer | Stage IV Pancreatic Cancer | Metastatic Malignant Solid Neoplasm | Metastatic Urothelial Carcinoma | Stage IV... and other conditions

United States
Krystal Biotech, Inc.

Recruiting

A Study Assessing KB707 for the Treatment of Advanced Solid Tumor Malignancies Affecting the Lungs

Metastatic Renal Cell Carcinoma | Metastatic Colorectal Cancer | Lung Cancer Metastatic | Lung Cancer, Non-small Cell | Advanced Cancer | Solid Tumor, Adult | Metastatic Osteosarcoma | Metastatic Sarcoma | Metastatic Hepatocellular Carcinoma | Lung Cancer, Small Cell

United States
Eli Lilly and Company
ARMO BioSciences

Active, not recruiting

A Phase 1 Study of Pegilodecakin (LY3500518) in Participants With Advanced Solid Tumors (IVY)

Melanoma | Renal Cell Carcinoma | Breast Cancer | Ovarian Cancer | Prostate Cancer | Non-small Cell Lung Carcinoma | Solid Tumors | Colorectal Carcinoma | Pancreatic Carcinoma

United States
National Cancer Institute (NCI)

Completed

VEGF Trap in Treating Patients With Recurrent, Locally Advanced, or Metastatic Cancer of the Urothelium

Metastatic Transitional Cell Cancer of the Renal Pelvis and Ureter | Recurrent Bladder Cancer | Recurrent Transitional Cell Cancer of the Renal Pelvis and Ureter | Stage III Bladder Cancer | Stage IV Bladder Cancer | Transitional Cell Carcinoma of the Bladder | Adenocarcinoma of the Bladder | Distal... and other conditions

United States
Hospices Civils de Lyon

Recruiting

Retrospective and Prospective Follow-up of Patients With Primary Hyperoxaluria Type 1 Treated With Lumasiran in France. (DAILY-LUMA)

Patients With PH1 Treated With Lumasiran in France

France
Assistance Publique - Hôpitaux de Paris

Recruiting

AMIloride for the Treatment of Nephrogenic Diabetes Insipidus for Patients With Bipolar Disorder Treated With Lithium (AMIND)

Bipolar Disorder

France
Hoffmann-La Roche
Chugai Pharmaceutical

Recruiting

A Study Evaluating the Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of Crovalimab in Pediatric Participants With Atypical Hemolytic Uremic Syndrome (aHUS) (COMMUTE-p)

Atypical Hemolytic Uremic Syndrome

United States, Belgium, China, France, Spain, Canada, South Africa, Japan, Brazil, Italy, Poland, India, Hungary, Mexico, Israel
Shanghai Children's Hospital

Recruiting

Study of Hydroxychloroquine in Patients With X-linked Alport Syndrome in China (CHXLAS) (CHXLAS)

Alport Syndrome, X-Linked

China
Novartis Pharmaceuticals

Recruiting

Efficacy and Safety of Iptacopan (LNP023) in Adult Patients With Atypical Hemolytic Uremic Syndrome Naive to Complement Inhibitor Therapy (APPELHUS)

Atypical Hemolytic Uremic Syndrome

China, Korea, Republic of, Austria, Taiwan, Greece, Czechia, United States, Japan, Brazil, United Kingdom, India, Slovakia, Slovenia
Apellis Pharmaceuticals, Inc.

Available

C3G/Primary IC-MPGN EAP

C3G | IC-MPGN | C3 Glomerulopathy | C3 Glomerulonephritis | Complement 3 Glomerulopathy | Complement 3 Glomerulopathy (C3G) | Complement 3 Glomerulonephritis | Dense Deposit Disease | DDD | Membranoproliferative Glomerulonephritis | Membranoproliferative Glomerulonephritis (MPGN) | Immune Complex Membranoproliferative...

United States
Apellis Pharmaceuticals, Inc.

Active, not recruiting

Phase III Study Assessing the Efficacy and Safety of Pegcetacoplan in Patients With C3 Glomerulopathy or Immune-Complex Membranoproliferative Glomerulonephritis (VALIANT)

C3G | IC-MPGN | C3 Glomerulopathy | C3 Glomerulonephritis | Complement 3 Glomerulopathy | Complement 3 Glomerulopathy (C3G) | Complement 3 Glomerulonephritis | Dense Deposit Disease | DDD | Membranoproliferative Glomerulonephritis | Membranoproliferative Glomerulonephritis (MPGN) | Immune Complex Membranoproliferative...

United States, Spain, France, Germany, United Kingdom, Netherlands, Brazil, Israel, Japan, Australia, Austria, Italy, Switzerland, Korea, Republic of, Czechia, Belgium, Argentina, Canada, Poland
Apellis Pharmaceuticals, Inc.

Active, not recruiting

An Open-Label, Nonrandomized, Multicenter Extension Study to Evaluate the Long-term Safety and Efficacy of Pegcetacoplan in Participants With C3 Glomerulopathy or Immune-Complex Membranoproliferative Glomerulonephritis (VALE)

C3G | IC-MPGN | C3 Glomerulopathy | C3 Glomerulonephritis | Complement 3 Glomerulopathy | Complement 3 Glomerulopathy (C3G) | Complement 3 Glomerulonephritis | Dense Deposit Disease | DDD | Membranoproliferative Glomerulonephritis | Membranoproliferative Glomerulonephritis (MPGN) | Immune Complex Membranoproliferative...

United States, Australia, Brazil, Czechia, France, Italy, Korea, Republic of, Netherlands, Spain, Switzerland, United Kingdom
Otsuka Pharmaceutical Co., Ltd.

Completed

A Multicenter Trial to Investigate the Efficacy and Safety of Tolvaptan in Patients With Hyponatremia in SIADH

Syndrome of Inappropriate Antidiuretic Hormone Secretion

Japan
Nanjing Children's Hospital

Unknown

The Research of Standard Diagnosis and Treatment for HSPN With Mild Proteinuria in Children

Henoch-Schoenlein Purpura Nephritis

China
Dr Anders Ullén

Completed

A Trial With Vinflunine in Patients With Metastatic Bladder Cancer and Impaired Renal Function (VINGEM)

Bladder Cancer | Urothelial Carcinoma | Urethra Cancer | Ureter Cancer | Renal Pelvis Cancer

Denmark, Sweden
Poitiers University Hospital

Completed

Copeptin and the S-100b Protein in Stroke

Vertigo, Peripheral | Vertigo, Brain Stem | Vertigo; Central | Vertigo; Cerebral
Otsuka Pharmaceutical Development & Commercialization...

Completed

A PK Study of 3 Dosages of Tolvaptan in Patients With Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH)

Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH)

Germany, United Kingdom, Spain, Sweden, Hungary, Czech Republic, Denmark
Peking University First Hospital

Recruiting

Fractional Flow Reserve-guided Stenting Versus Medical Therapy in Atherosclerosis Renal Artery Stenosis (FAIR)

Renal Artery Stenosis Atherosclerotic | Secondary Hypertension Renal Arterial

China
Hospital Universitario 12 de Octubre

Not yet recruiting

Registry of Patients in Shock Treated With Vasopressin

Shock | Vasopressor Adverse Reaction | Vasopressin Causing Adverse Effects in Therapeutic Use | Vasopressin Deficiency

Spain
Sohag University

Not yet recruiting

the Association Between Metabolic Syndrome and Its Components With Lupus Nephritis in Systemic Lupus Erythematosus Patients

Lupus Nephritis

Egypt
Novartis Pharmaceuticals

Recruiting

Efficacy and Safety of Switching From Anti-C5 Antibody Treatment to Iptacopan Treatment in Study Participants With Atypical Hemolytic Uremic Syndrome (aHUS)

Atypical Hemolytic Uremic Syndrome

Japan, Turkey
Institut National de la Santé Et de la Recherche...

Recruiting

Eurbio-Alport (RaDiCo Cohort) (RaDiCo Eurbio-Alport) (Eurbio-Alport)

Alport Syndrome

France
Novartis Pharmaceuticals

Recruiting

Evaluate Long-term Safety, Tolerability and Efficacy of Iptacopan in Study Participants With aHUS

Atypical Hemolytic Uremic Syndrome

Brazil
NovelMed Therapeutics

Not yet recruiting

Study of NM8074 in Patients With aHUS With Evidence of Ongoing Thrombotic Microangiopathy

aHUS - Atypical Hemolytic Uremic Syndrome
Dicerna Pharmaceuticals, Inc., a Novo Nordisk company

Recruiting

Nedosiran in Pediatric Patients From Birth to 11 Years of Age With PH and Relatively Intact Renal Function (PHYOX8)

Primary Hyperoxaluria Type 3 | Primary Hyperoxaluria Type 2 | Primary Hyperoxaluria Type 1 | Primary Hyperoxaluria

United States, Canada, Lebanon, Turkey, United Kingdom, Germany, Italy, Japan, Poland, Spain, United Arab Emirates
Vastra Gotaland Region

Completed

Accuracy and Treatment Experience of Two Glucose Monitoring Systems Tested in Patients With Type 1 Diabetes and Renal Impairment

Renal Impairment | Diabetes Mellitus Complication

Sweden
The Hospital for Sick Children

Completed

Hydroxychloroquine Administration for Reduction of Pexophagy (HARP)

Zellweger Syndrome | Peroxisome Biogenesis Disorders

Canada
ViiV Healthcare

Completed

Pharmacokinetics Study of GSK1265744 in Subjects With Severe Renal Impairment

HIV Infections | Infection, Human Immunodeficiency Virus

United States
University of Aarhus

Completed

Effect of Gastric Bypass Surgery on Diabetes Status and Microvascular Complications in Obese Type 2 Diabetic Patients

Obesity | Type 2 Diabetes Mellitus | Diabetic Retinopathy | Diabetic Nephropathy

Denmark
Alexion Pharmaceuticals

Completed

Safety and Efficacy Study of Eculizumab in Shiga-Toxin Producing Escherichia Coli Hemolytic-Uremic Syndrome (STEC-HUS) (STEC-HUS)

Shiga-like Toxin-producing Escherichia Coli

Germany
Peking University First Hospital

Recruiting

Fractional Flow Reserve to Determine Atherosclerosis Renovascular Hypertension Stenting (FAIR-Pilot)

Renal Artery Stenosis Atherosclerotic | Secondary Hypertension Renal Arterial

China
Alice Bertaina
California Institute for Regenerative Medicine (CIRM)

Recruiting

Early Trial of Allogeneic Hematopoietic Stem Cell Transplantation for Patients Who Will Receive a Kidney Transplant From the Same Donor

CKD Stage 4 | Cystinosis | FSGS | SLE Nephritis | SIOD

United States
Hoffmann-La Roche
Chugai Pharmaceutical

Recruiting

A Study Evaluating the Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of Crovalimab in Adult and Adolescent Participants With Atypical Hemolytic Uremic Syndrome (aHUS) (COMMUTE-a)

Atypical Hemolytic Uremic Syndrome

Canada, United States, Japan, France, Spain, Mexico, Peru, Brazil, New Zealand, Belgium, China, Germany, Hungary, Israel, Italy, Poland, South Africa, Turkey, India
Maastricht University Medical Center

Recruiting

Complement Prospective Evaluation of Thrombotic Microangiopathy on Endothelium (COMPETE)

Thrombotic Microangiopathies | Hemolytic-Uremic Syndrome | Hemolytic Uremic Syndrome, Atypical

Netherlands
SynAct Pharma Aps

Recruiting

A Study of the Safety, Tolerability, Pharmacokinetics and Efficacy of Treatment With AP1189 in Patients With iMN and Severe Proteinuria

Nephrotic Syndrome Due to Idiopathic Membranous Nephropathy | Severe Proteinuria Due to Idiopathic Membranous Nephropathy

Denmark
Hospices Civils de Lyon

Recruiting

CYSTEA-BONE Clinical Study (CYSTEA-BONE)

Nephropathic Cystinosis

France, Germany, Italy, Turkey
Progenity, Inc.

Completed

Collection of Samples From Pregnant Women for the Evaluation of Preeclampsia (Pre-E) Biomarkers

Hypertension | Renal Insufficiency | Proteinuria | Thrombocytopenia | Preeclampsia | Pulmonary Edema | Impaired Liver Function

United States
University of Tennessee, Chattanooga

Withdrawn

Airway Pressure Release Ventilation (APRV) Compared to ARDSnet Ventilation (PRESSURE)

Acute Lung Injury | Kidney Injury | Adult Respiratory Distress Syndrome

United States
Universitaire Ziekenhuizen KU Leuven

Completed

Prematurity as Predictor of Children's Cardiovascular-renal Health (PREMATCH)

Renal Impairment | Ventricular Dysfunction, Left | Endothelial Dysfunction | Visual Disturbances and Blindness | Sublingual Capillary Glycocalyx and Density

Belgium
Hoffmann-La Roche

Completed

A Study Of Mircera In Patients With Kidney Disease Who Are Not On Dialysis

Renal Tubular Acidosis, Distal, With Hemolytic Anemia

Serbia
AHEPA University Hospital
Aristotle University Of Thessaloniki

Unknown

Ramipril and Clopidogrel in Oxidative Stress, Vascular Inflammation and Endothelial Dysfunction in Type 2 Diabetes and Diabetic Nephropathy

Diabetic Nephropathy | Diabetes Type 2 | Vascular Disease

Greece
Masonic Cancer Center, University of Minnesota

Active, not recruiting

UCB Transplant for Hematological Diseases Using a Non Myeloablative Prep

Follicular Lymphoma | Acute Myeloid Leukemia | Multiple Myeloma | Hodgkin Lymphoma | Lymphoplasmacytic Lymphoma | Acute Leukemia | Myelodysplastic Syndrome | Chronic Myelogenous Leukemia | Prolymphocytic Leukemia | Plasma Cell Leukemia | Bone Marrow Failure Syndromes | Burkitt's Lymphoma | Acute Lymphoblastic Leukemia... and other conditions

United States
Siriraj Hospital

Recruiting

The Efficacy of P0.1-guided Sedation Protocol in Critically Ill Patients Receiving Invasive Mechanical Ventilation: A Randomized Controlled Trial

Critical Illness | Respiratory Failure | Lung Injury | Respiratory Distress Syndrome, Adult | Mechanical Ventilation Complication

Thailand
Assiut University

Not yet recruiting

HVNI Versus NIV In Management Of Acute Hypercapnic Respiratory Failure In OHS

Obesity Hypoventilation Syndrome (OHS)
University of Calgary
Alberta Health services

Recruiting

Identification and Treatment of Hypoxemic Respiratory Failure and ARDS With Protection, Paralysis, and Proning Pathway

Acute Respiratory Distress Syndrome | ARDS, Human | Hypoxemic Respiratory Failure

Canada
University Medical Centre Ljubljana

Active, not recruiting

Conduction System Pacing Versus Biventricular Pacing for Cardiac resYNChronization (CSP-SYNC)

Heart Failure | Left Bundle-Branch Block | Cardiac Remodeling, Ventricular | Dilated Cardiomyopathy With Conduction Defect | Resynchronization Therapy

Slovenia
Groupe Hospitalier Paris Saint Joseph

Completed

Predictors of Non-accESs to therapeutiC EducAtion Programs Among Patients With Type 2 Diabetes, and/or Asthma, and/or Chronic Heart Failure in an Emergency Setting (ESCAPE)

Heart Failure | Diabetes | Emergencies | Asthma | Therapeutic Education Program

France
Arbor Research Collaborative for Health
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

Adult-to-Adult Living Donor Transplant Cohort Study (A2ALL-2)

End Stage Liver Disease | Liver Diseases | Liver Cirrhosis | Hepatitis C | Hepatocellular Cancer

United States, Canada
Bispebjerg Hospital

Completed

The Copenhagen City Heart Study (CCHS)

Myocardial Infarction | Heart Failure | Stroke | Cancer | Chronic Obstructive Pulmonary Disease | Coronary Heart Disease

Clinical Trials on Transplant;Failure,Kidney

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