Clinical Trials on Transplantation, Liver

Total 15192 results

Astellas Pharma Europe Ltd.

Completed

A Study to Compare How the Body Absorbs and Processes Two Different Formulations of the Anti-rejection Medication Tacrolimus (Advagraf® or Prograf®) in Children Receiving an Organ Transplant, and How Safe and Effective They Are Over a Longer Period of Time

Liver Transplantation | Kidney Transplantation | Heart Transplantation

Czechia, France, Italy, Poland, United Kingdom
The Hospital for Sick Children

Completed

Pharmacogenetic Trial of Tacrolimus After Pediatric Transplantation

Liver Transplantation | Kidney Transplantation | Heart Transplantation

Canada
Astellas Pharma Europe Ltd.

Terminated

A Paediatric, Open, Follow up Study With Modigraf Examining Safety and Efficacy in de Novo Allograft Recipients (PROGRESSION)

Liver Transplantation | Kidney Transplantation | Heart Transplantation

Belgium, France, Germany, Poland, Spain, United Kingdom
Astellas Pharma Europe Ltd.

Completed

Study to Ascertain if Prolonged Release Tacrolimus (FK506E - MR4) is Safe and Effective When Used in the Long Term and in Combination With Other Immunosuppressive Drugs in Patients Who Have Received a Transplant

Liver Transplantation | Kidney Transplantation | Heart Transplantation

Spain, Australia, France, Germany, Canada, Italy, United Kingdom, Belgium, South Africa, Switzerland, Sweden, United States, Austria, Brazil, Czechia, Denmark, Finland, Hungary, Ireland, Mexico, Netherlands, New Zealand, Poland
Astellas Pharma Europe Ltd.

Completed

A Study to Determine Pharmacokinetics of Children Receiving Modigraf (Tacrolimus Granules) Following Solid Organ Transplantation (OPTION)

Liver Transplantation | Kidney Transplantation | Heart Transplantation

Belgium, France, Germany, Poland, Spain, United Kingdom
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Treg Cell Therapy in Liver and Kidney Transplantation - Preclinical Validation of Batches of Treg Cells Amplified in Vitro (PRE-TREG)

Liver Transplantation | Kidney Transplantation

France
Astellas Pharma China, Inc.

Completed

A Study to Evaluate the Safety and Efficacy of a Modigraf® Based Immunosuppression Regimen in De Novo Pediatric Allograft Liver and Kidney Transplantation Recipients

Liver Transplantation | Kidney Transplantation

China
Astellas Pharma China, Inc.

Completed

A Study of Modigraf® (Tacrolimus Granules) to Evaluate the Pharmacokinetics and Long-term Safety and Efficacy in De Novo Pediatric Allograft Liver and Kidney Transplantation Recipients

Liver Transplantation | Kidney Transplantation

China
Rennes University Hospital

Completed

Impact of P-gp, MRP2, ENT-1 and CNT3 on the Blood Concentration / Intra-PBMC Concentration of Tacrolimus (TRANS-TAC)

Liver Transplantation | Kidney Transplantation

France
Helsinki University Central Hospital
Tampere University Hospital

Completed

Immunogenicity of 13-valent Pneumococcal Conjugate Vaccine Compared to the Pneumococcal Polysaccharide Vaccine in Adult Kidney and Liver Transplant Patients (SOT13)

Liver Transplantation | Kidney Transplantation

Finland
National Taiwan University Hospital

Unknown

The Influence of ABCB1、CYP3A4、CYP3A5、POR Genetic Polymorphism and Other Factors on Tacrolimus Blood Concentration

Liver Transplantation | Kidney Transplantation

Taiwan
Astellas Pharma Inc

Completed

A Study to Demonstrate Safety and Efficacy of Advagraf in Patients Undergoing Kidney or Liver Transplantation in India

Liver Transplantation | Kidney Transplantation

India
National Taiwan University Hospital
National Science Council, Taiwan

Unknown

Organ Transplantation Rehabilitation: Effect of Bedside Exercise Device and Activity Reinforcement

Liver Transplantation | Heart Transplantation

Taiwan
Novartis

Completed

Conversion Trial From Mycophenolate Mofetil (MMF) to Enteric-coated Mycophenolate Sodium (EC-MPS) in Stable Transplanted Patients Suffering From Gastrointestinal (GI) Adverse Events While on Mycophenolate Mofetil Therapy (MMF) Therapy

Liver Transplantation | Kidney Transplantation

Switzerland
University of Wisconsin, Madison

Terminated

Cytokine Kinetics Test to Assess the Presence or Absence of Tolerance in Organ Transplant

Liver Transplantation | Kidney Transplantation

United States
Astellas Pharma Europe Ltd.

Active, not recruiting

Study to Compare the Pharmacokinetics of Tacrolimus in Stable Pediatric Allograft Recipients Converted From Prograf® to Advagraf®

Liver Transplantation | Kidney Transplantation | Heart Transplantation | Lung Transplantation | Intestine Transplantation

Belgium, Czechia, France, Germany, Italy, Poland, United Kingdom
National Institute of Allergy and Infectious Diseases...
PPD; Rho Federal Systems Division, Inc.; Immune Tolerance Network (ITN)

Completed

Evaluation of Donor Specific Immune Senescence and Exhaustion as Biomarkers of Tolerance Post Liver Transplantation (OPTIMAL)

Liver Transplantation | Liver Transplant

United States
National Institute of Allergy and Infectious Diseases...
Immune Tolerance Network (ITN)

Completed

Withdrawal of Immunosuppression in Pediatric Liver Transplant Recipients (WISP-R)

Liver Transplantation | Liver Transplant

United States
Johns Hopkins University

Completed

A Study of mDOT for Immunosuppressant Adherence in Solid Organ Transplant Recipients

Liver Transplantation | Medication Adherence | Kidney Transplantation

United States
National Institute of Allergy and Infectious Diseases...
Clinical Trials in Organ Transplantation

Completed

Discovery and Validation of Proteogenomic Biomarker Panels in Liver Transplant Recipients (PROGENI-LI)

Liver Transplantation | Liver Transplant Recipients

United States
Organ Recovery Systems, Inc.

Recruiting

Continued Access Study to Evaluate Performance of the Organ Recovery Systems _LifePort® Liver Transporter System, a Machine Perfusion System, for Liver Transplant (PILOT™_CA) (PILOT™_CA)

Liver Transplantation

United States
Chang Gung Memorial Hospital
Astellas Pharma Taiwan, Inc.

Recruiting

A Study of Patient Adherence and Convenience to Immunosuppressive Agents in Newly Liver Transplant

Liver Transplantation

Taiwan
Rennes University Hospital

Recruiting

APCext : Effect of Temporary Porto-caval Shunt During Liver Transplantation on Function of Liver Graft From Extended Criteria Donor (APCext)

Liver Transplantation

France
University Hospital, Bordeaux

Completed

Rapid Diagnostic of Hyperfibrinolysis in Liver Transplantation (FILYTHO)

Liver Transplantation

France
University of Southern California

Enrolling by invitation

Transportation Assistance Program for Liver Transplant (TAP-LT)

Liver Transplantation

United States
Shanghai General Hospital, Shanghai Jiao Tong University...

Completed

Tumor Feeding Vessels Deprivation Combined With Tyrosine Kinase Inhibitor in Liver Transplantation

Liver Transplantation

China
Beth Israel Deaconess Medical Center

Completed

Efficacy of Low Dose, SubQ Interleukin-2 (IL-2) to Expand Endogenous Regulatory T-Cells in Liver Transplant Recipients

Liver Transplantation

United States
Assistance Publique - Hôpitaux de Paris

Terminated

Removable Intraductal Stenting in Duct-to-duct Biliary Reconstruction in Liver Transplantation (BILIDRAINT)

Transplantation, Liver

France
Rennes University Hospital

Completed

Interest of an Early Rehabilitation Program in Liver Transplant Surgery (RAC-TH)

Liver Transplantation

France
University Hospital Heidelberg

Unknown

Evaluation of the Impact of Tacrolimus-based Immunosuppression on Heidelberg Liver Transplant Cohort (HDTACRO): Study Protocol for an Investigator Initiated, Non-interventional Prospective Study

Liver Transplantation

Germany
Pitié-Salpêtrière Hospital

Unknown

INTERNATIONAL SURVEY ON COMPLEXITY IN LIVER TRANSPLANTATION

Liver Transplantation

France
Novartis Pharmaceuticals

Completed

Efficacy of Everolimus in Combination With Tacrolimus in Liver Transplant Recipients (HEPHAISTOS)

Liver Transplantation

Germany
Novartis Pharmaceuticals

Completed

Efficacy and Safety of Everolimus in Liver Transplant Recipients of Living Donor Liver Transplants

Liver Transplantation

United States, Japan, Saudi Arabia, Taiwan, Egypt, Italy, Korea, Republic of, Germany, India, Canada, Russian Federation, Singapore, Turkey
The Cleveland Clinic
Genzyme, a Sanofi Company

Completed

Low Dose Thymoglobulin to Protect Kidney Function After Liver Transplant

Liver Transplantation

United States
Taipei Veterans General Hospital, Taiwan
Duke University

Unknown

Physiological Data Analysis of Patients Undergoing Anesthesia for Liver Transplantation

Liver Transplantation
Kim, Seoung-Hoon
Astellas Pharma Korea, Inc.; Linical Korea

Completed

To Evaluate the Efficacy and Safety of ADVAGRAF® After Treatment With a Tacrolimus in New Liver Transplant Recipients

Liver Transplantation
Hopital Foch

Terminated

Closed-loop Anesthesia, Using Bispectral Index as the Control Variable, During Liver Transplantation (Drone-TH)

Liver Transplantation

France
Astellas Pharma Inc

Completed

A Study to Compare the Efficacy and Safety of FK506MR vs Prograf® in Patients Undergoing Liver Transplantation

Liver Transplantation

China
Astellas Pharma Inc

Completed

Comparing Efficacy & Safety of Tacrolimus With/Without MMF or Monoclonal Anti-IL2R Antibody in Liver Transplantation. (MARSILEA)

Liver Transplantation

Belgium, Germany, Italy, Switzerland, Spain, Denmark, United Kingdom, Hungary, Finland, Sweden, Poland
Astellas Pharma Inc

Completed

Tacrolimus and Daclizumab Versus Tacrolimus and Steroids in Liver Recipients Receiving Sub-optimal Grafts (PANTERA)

LIVER TRANSPLANTATION

Italy
Astellas Pharma Inc

Completed

Sequential Therapy (FK506 + Monoclonal Anti-IL2R Antibodies + MMF) Versus FK506 With Steroids in Liver TX (TAST)

Liver Transplantation

Italy
University Health Network, Toronto

Unknown

Duct-to-duct vs Roux-en-y Hepaticojejunostomy for Biliary Reconstruction in Adult Living Donor Liver Transplantation

Liver Transplantation

Canada
Astellas Pharma Inc

Completed

A Study to Evaluate the Safety and Efficacy of FK506E (MR4) in Patients Undergoing Primary Liver Transplantation.

Liver Transplantation

France, Italy, Poland, Belgium, Spain, Germany, Switzerland, Canada, Finland, Brazil, Czech Republic, Australia, Norway, Sweden, United Kingdom, Ireland
Samsung Medical Center

Completed

Vecuronium Requirements According to the Operation Phase During Liver Transplantation Under Desflurane Anesthesia

Liver Transplantation

Korea, Republic of
Hospital Clinic of Barcelona

Terminated

Pilot Study of Immunosuppression Drug Weaning in Liver Recipients Exhibiting Biomarkers of High Likelihood of Tolerance

Liver Transplantation

Spain
University Hospital, Limoges

Completed

Reduction in the Risk of Rejection by Mycophenolate Mofetil Dose Adjustment in Liver Transplant Patients With Side Effects Caused by the Calcineurine Inhibitors (MONOCEPT)

Liver Transplantation

France
Seoul National University Hospital

Completed

Effect of Rapid Transfusion With Fluid Management System 2000® (FMS) (FMS)

Liver Transplantation

Korea, Republic of
Yonsei University

Completed

The Predictors for Continuous Renal Replacement Therapy in Liver Transplant Patient

Liver Transplantation

Korea, Republic of
University of Erlangen-Nürnberg Medical School

Unknown

Acoustic Radiation Force Impulse Imaging (ARFI) in Patients After Liver Transplantation

Liver Transplantation

Germany
University Hospital, Gentofte, Copenhagen
University of Copenhagen

Unknown

Intact Liver Innervation and Glucose and Glucagon-like Peptide-1 (GLP-1) Induced Insulin Secretion

Liver Transplantation

Denmark

3

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