Clinical Trials on Tumors, Central Nervous System

Total 141628 results

Roswell Park Cancer Institute
National Cancer Institute (NCI)

Withdrawn

Sirolimus and Vaccine Therapy in Treating Patients With Stage II-IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

Recurrent Fallopian Tube Carcinoma | Recurrent Ovarian Carcinoma | Recurrent Primary Peritoneal Carcinoma | Stage IIA Fallopian Tube Cancer | Stage IIA Ovarian Cancer | Stage IIB Fallopian Tube Cancer | Stage IIB Ovarian Cancer | Stage IIC Fallopian Tube Cancer | Stage IIC Ovarian Cancer | Stage IIIA Fallopian... and other conditions

United States
UCSF Benioff Children's Hospital Oakland
Genentech, Inc.

Completed

Trial Comparing the Effects of Intermittent Vismodegib vs. PDT in Patients With Multiple Basal Cell Carcinomas (Vismodegib)

Basal Cell Nevus Syndrome | Gorlin's Syndrome

United States
Anne Chang
Novartis Pharmaceuticals

Terminated

Pilot Study of Sonidegib and Buparlisib in Treating Patients With Advanced or Metastatic Basal Cell Carcinoma

Carcinoma, Basal Cell | Skin Neoplasms | Basal Cell Nevus Syndrome | Recurrent Skin Cancer

United States
Yale University
National Cancer Institute (NCI)

Completed

Topical Sirolimus in Patients With Basal Cell Nevus Syndrome and in Healthy Participants

Non-melanomatous Skin Cancer | Neoplastic Syndrome
National Cancer Institute (NCI)

Terminated

Obatoclax and Bortezomib in Treating Patients With Aggressive Relapsed or Recurrent Non-Hodgkin Lymphoma

Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma | Recurrent Grade 3 Follicular Lymphoma | Recurrent Mantle Cell Lymphoma | Recurrent Marginal Zone Lymphoma | Recurrent Small Lymphocytic Lymphoma | Adult Non-Hodgkin Lymphoma

United States
University of Colorado, Denver

Completed

Health, Fitness, and Quality of Life in Adolescent Girls With Turner Syndrome

Turner Syndrome | Turner Syndrome Mosaicism, 45, X/46, XX or XY | Turner Syndrome Mosaicism 46,X,I(X)(Q10)/45,X | Turner Syndrome Karyotype 46,X With Abnormal Sex Chromosome , Except I(Xq)

United States
Asan Medical Center
Astellas Pharma Korea, Inc.

Unknown

Micafungin Prevention Study for Fungal Disease in Child Receiving Allogenic Hematopoietic Stem Cell Transplantation

Neutropenia | Hematopoietic Stem Cell Transplantation | Invasive Fungal Disease

Korea, Republic of
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Gardasil 9 Vaccine in Preventing HPV Infection in Patients With Hematologic Malignancies Undergoing Donor Stem Cell Transplant

Hematopoietic and Lymphoid Cell Neoplasm | Allogeneic Hematopoietic Stem Cell Transplant Recipient

United States
Zachariah Michael DeFilipp
Regimmune Corporation

Active, not recruiting

Haplo Peripheral Blood Sct In GVHD Prevention

Acute Myeloid Leukemia | Myelodysplastic Syndromes | Hodgkin Lymphoma | Chronic Myelomonocytic Leukemia | Acute Lymphoblastic Leukemia | AML | Non Hodgkin Lymphoma | MDS | Myeloproliferative Disorder | GVHD | Graft Vs Host Disease | ALL | CMML | Blood Stem Cell Transplant Failure | MPN | Chemosensitive Hodgkin Lymphoma

United States
Occyo GmbH
University Clinic for Ophthalmology and Optometry- Salzburg

Completed

CDL Validation Study

Limbal Stem-cell Deficiency | Cornea Disease | Eyes Dry Chronic | Chronic Conjunctivitis of Both Eyes | Eye Lesion | Eye Disease; Cataract | Eyes Dry Feeling of | Cornea Inflamed | Cornea; Injury, Abrasion | Cornea Infection

Austria
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Completed

Music in Reducing Anxiety and Pain in Adult Patients Undergoing Bone Marrow Biopsy for Hematologic Cancers or Other Diseases

Pain | Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Multiple Myeloma and Plasma Cell Neoplasm | Precancerous Condition | Psychosocial Effects of Cancer and Its Treatment | Lymphoproliferative Disorder | Myelodysplastic/Myeloproliferative Neoplasms

United States
The Lymphoma Academic Research Organisation
Lymphoma Study Association

Not yet recruiting

Golcadomide Post-CAR T-cell in R/R Aggressive Large B-cell Lymphoma Patients With High Risk of Relapse

Refractory High Grade B-Cell Lymphoma | Diffuse Large B-cell Lymphoma Refractory | Refractory Transformed B-cell Non-Hodgkin Lymphoma | Refractory Primary Mediastinal Large B-Cell Lymphoma

France
University of Modena and Reggio Emilia
Azienda USL - IRCCS di Reggio Emilia

Recruiting

The Unmet Needs of Cancer Survivors in Ausl IRCCS Reggio Emilia (Survivorship)

Neoplasms | Lymphoma | Cancer | Breast Cancer | Multiple Myeloma | Colorectal Cancer | Prostate Cancer | Thyroid Cancer

Italy
National Cancer Institute, Naples

Not yet recruiting

PRO for Fighting FT in Ovarian Cancer (MITO45-ProFFiT)

Ovarian Cancer

Italy
Northwestern University
National Cancer Institute (NCI)

Recruiting

Vudalimab for the Treatment of Locally Advanced or Metastatic Anaplastic Thyroid Cancer or Hurthle Cell Thyroid Cancer

Locally Advanced Thyroid Gland Anaplastic Carcinoma | Metastatic Thyroid Gland Anaplastic Carcinoma | Metastatic Thyroid Gland Oncocytic Carcinoma

United States
SWOG Cancer Research Network
National Cancer Institute (NCI)

Active, not recruiting

Treatment Effects on Development of Chemotherapy-Induced Peripheral Neuropathy in Patients With Cancer

Anatomic Stage I Breast Cancer AJCC v8 | Anatomic Stage IA Breast Cancer AJCC v8 | Anatomic Stage IB Breast Cancer AJCC v8 | Anatomic Stage II Breast Cancer AJCC v8 | Anatomic Stage IIA Breast Cancer AJCC v8 | Anatomic Stage IIB Breast Cancer AJCC v8 | Anatomic Stage III Breast Cancer AJCC v8 | Anatomic... and other conditions

United States, Colombia, Mexico, Chile
Advocate Health Care

Completed

Psychometric Properties of the SMART Feeding Tool

Trauma and Stressor Related Disorders | Nurse's Role | Premature Infant Disease | Feeding; Difficult, Newborn | Malnutrition, Infant | Dysphagia of Newborn | Feeding Disorder of Infancy or Early Childhood | Deglutition Disorders in Infants

United States
M.D. Anderson Cancer Center

Active, not recruiting

Prophylactic Salpingectomy With Delayed Oophorectomy

Ovarian Carcinoma

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Talazoparib and Radiation Therapy in Treating Patients With Locally Recurrent Gynecologic Cancers

Recurrent Fallopian Tube Carcinoma | Recurrent Ovarian Carcinoma | Recurrent Primary Peritoneal Carcinoma | Recurrent Endometrial Carcinoma | Stage IV Uterine Corpus Cancer AJCC v8 | Stage IVA Uterine Corpus Cancer AJCC v8 | Stage IVB Uterine Corpus Cancer AJCC v8 | Recurrent Cervical Carcinoma | Malignant... and other conditions

United States
Vienna Hospital Association

Recruiting

Non-invasive Nervus Vagus Stimulation in Patients With COVID-19 and ARDS

COVID-19 | ARDS | Cytokine Storm

Austria
The First Affiliated Hospital of Soochow University

Recruiting

Application of Nanopore Sequencing in Newly Diagnosed Acute Myeloid Leukemia Patients With Bloodstream Infection

Acute Myeloid Leukemia | Gut Microbiota | Blood Stream Infection

China
Todd C. Lee MD MPH FIDSA

Recruiting

Combination Cefazolin With Ertapenem for Methicillin-susceptible Staphylococcus Aureus Bacteremia (CERT)

Staphylococcus Aureus Bacteremia | Staphylococcus Aureus Endocarditis | Staphylococcus Aureus Septicemia | Staphylococcal Sepsis

Canada
Olatec Therapeutics LLC
CTI Clinical Trial and Consulting Services

Terminated

Safety and Efficacy of Dapansutrile for Treatment of Moderate COVID-19 Symptoms and Evidence of Early Cytokine Release Syndrome

Covid19 | Cytokine Release Syndrome

United States, Switzerland
Prisma Health-Upstate

Completed

Therapeutic Plasma Exchange Alone or in Combination With Ruxolitinib in COVID-19 Associated CRS

COVID19 | Cytokine Release Syndrome

United States
Avicenna Research Institute
Tehran University of Medical Sciences

Completed

Menstrual Blood Stem Cells in Severe Covid-19

Covid19 | Cytokine Storm

Iran, Islamic Republic of
William Beaumont Hospitals

Terminated

Betadine Bladder Irrigations vs. Standard of Care Prior to Indwelling Catheter Removal

Urinary Tract Infections | Catheter Infection | Catheter-Related Infections | Catheter; Infection (Indwelling Catheter) | Catheter Bacteraemia

United States
Children's Hospital of Philadelphia
Patient-Centered Outcomes Research Institute; Baylor College of Medicine; Dana-Farber... and other collaborators

Completed

Home Away From Home - Medical Outcomes (Aim 1)

Acute Myeloid Leukemia | Neutropenia | Bacteremia

United States
University College, London
Medical Research Council

Completed

Zibotentan Better Renal Scleroderma Outcome Study (ZEBRA)

Chronic Kidney Disease | Scleroderma | Scleroderma Renal Crisis

United Kingdom
Maastricht University Medical Center
Dirinco B.V.

Terminated

Concentrated Citrate Locking to Reduce the Incidence of CVC-related Complications in Hematological Patients

Thrombosis | Bacteremia | Hematological Malignancies

Netherlands
University Hospital Hradec Kralove
American Association for Thoracic Surgery

Recruiting

AOrtic Surgery: Systemic Inflammatory Response Versus Sepsis (AOSIS)

Infections | Systemic Inflammatory Response Syndrome | Immunological Abnormality | Aortic Diseases | Thoracic Aortic Aneurysm

Czechia
Cardio Med Medical Center
George Emil Palade University of Medicine, Pharmacy, Sciences and Technology... and other collaborators

Completed

Impact of Cardiac Rehabilitation Programs on Left Ventricular Remodeling After Acute Myocardial Infarction - the REHAB Trial

Acute Coronary Syndrome | Acute Myocardial Infarction | Systemic Inflammation | Ventricular Remodeling | Non-ST Elevation Myocardial Infarction

Romania
Benha University

Completed

Intercellular Adhesion Molecule-1 and TNF-α in Patients With COVID-19

COVID-19 | Cytokine Storm

Egypt
Bactiguard AB
Danderyd Hospital

Terminated

BIP CVC in Access Center at Danderyd Hospital, Stockholm, Sweden (IMPROWE)

Catheter-Related Infections | Catheter Bacteraemia | Vascular Access Complication | Catheter Complications | Catheter Site Discomfort | Catheter Blockage | Catheter Thrombosis

Sweden
UNICEF
Pak Emirates Military Hospital Rawalpindi

Completed

Therapeutic Plasma Exchange for Coronavirus Disease-2019 Triggered Cytokine Release Storm; (Plex)

COVID-19 | Cytokine Release Syndrome

Pakistan
Koç University

Completed

Turkish Prospective Cohort Study on Carbapenem Resistant Klebsiella Pneumonia Bacteremia (THREAT)

Bacteremia | Klebsiella Pneumonia

Turkey
Firat Ergin

Completed

Is Neutrophil to Lymphocyte Ratio a Prognostic Factor of Sepsis in Newborns With Operated Congenital Heart Disease

Sepsis Newborn
Institute of Liver and Biliary Sciences, India

Unknown

Early Versus Late Sustained Low Efficiency Dialysis in Critically Ill Cirrhotics With Septic Shock and Acute Kidney Injury

Cirrhotics With Septic Shock and Acute Kidney Injury

India
Virginia Commonwealth University

Completed

Ascorbic Acid (Vitamin C) Infusion in Human Sepsis

Sepsis | Septic Shock | Hypotension | Acute Lung Injury

United States
Chinese PLA General Hospital

Completed

Diagnostic Value of sTREM-1 and PCT Level as Well as CPIS Score for Ventilator-Associated Pneumonia Among ICU Sepsis Patients

Sepsis | Ventilator-Associated Pneumonia

China
University of California, Irvine
Jarrow Formulas Inc

Not yet recruiting

Effect of NAC on Preventing Chemo-Related Cognitive Impairments in Ovarian Ca Pts Treated W/ PBT

Cognitive Impairment | Ovarian Cancer
Academic and Community Cancer Research United

Not yet recruiting

Epcoritamab Compared to Observation for Treating B-cell Lymphoma Patients Not in Complete Remission After CD19-directed CAR-T Therapy

Primary Mediastinal Large B-Cell Lymphoma | Diffuse Large B-Cell Lymphoma, Not Otherwise Specified | Transformed Indolent B-Cell Non-Hodgkin Lymphoma to Diffuse Large B-Cell Lymphoma

United States
Washington University School of Medicine
Genentech, Inc.

Recruiting

Mosunetuzumab in Combination With Platinum-Based Salvage Chemotherapy in Autologous Stem Cell Transplant-Eligible Patients With Relapsed/Refractory Aggressive B Cell Lymphoma

Diffuse Large B Cell Lymphoma | High-grade B-cell Lymphoma | Transformed B-Cell Lymphoma | Follicular Lymphoma Grade 3B

United States
Susan Lutgendorf
University of Miami; University of Iowa; University of Washington

Recruiting

Living WELL: A Web-Based Program for Ovarian Cancer Survivors

Ovarian Cancer

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Gemcitabine Hydrochloride, Clofarabine, and Busulfan Before Donor Stem Cell Transplant in Treating Patients With Refractory B-Cell or T-Cell Non-Hodgkin Lymphoma or Hodgkin Lymphoma

Refractory Hodgkin Lymphoma | Refractory B-Cell Non-Hodgkin Lymphoma | Refractory T-Cell Non-Hodgkin Lymphoma | Hematopoietic Cell Transplantation Recipient

United States
Harbin Medical University

Active, not recruiting

The Effect of a Psychosomatic Symptom Intervention Program on the Primary Treatment of Differentiated Thyroid Cancer

Pathologically Confirmed Differentiated Thyroid Carcinoma | All Patients Are in the Initial Treatment Phase | Normal Cognitive and Communicative Abilities, Capable of Reading and Understanding Questionnaires in Chinese | Ability to Use a Smartphone | Voluntary Participation in the Study...

China
Juan C. Ramos, MD

Withdrawn

Safety Trial of STING-dependent Activators and Stimulated Dendritic Cells for Aggressive Relapsed/Refractory Leukemias

Acute Lymphoblastic Leukemia | Acute Myelogenous Leukemia | Refractory Leukemia | Adult T-Cell Leukemia/Lymphoma | Relapsed Leukemia

United States
ARCAGY/ GINECO GROUP
Tesaro, Inc.

Completed

NIraparib and Quality Of LifE is a Longitudinal Study Evaluating in Real Life the Tolerability of Niraparib. (NiQoLe)

Ovarian Cancer

France
Puerta de Hierro University Hospital
Hospital de Basurto; Hospital Universitario Virgen Macarena; Hospital Universitario... and other collaborators

Recruiting

Evaluation of the Usefulness of Echocardiography in Patients With Staphylococcus Aureus Bacteremia (ET-AUREUS Study). (ET-AUREUS)

Infective Endocarditis | Staphylococcus Aureus Bacteremia

Spain
University of British Columbia

Recruiting

Smart Discharges for Mom & Baby

Neonatal Sepsis | Maternal Sepsis

Canada
University of Toledo Health Science Campus

Completed

Fluoxetine to Reduce Intubation and Death After COVID19 Infection

COVID-19 | Cytokine Storm

United States

Clinical Trials on Tumors, Central Nervous System

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