Clinical Trials on Twin Diseases in United Kingdom

Total 146728 results

Assaf-Harofeh Medical Center

Recruiting

Develop a Multi-disciplinary Approach for a Personalized Prenatal Diagnostics and Care for Twin Pregnancies (PRETWINSCREN)

Premature Birth | Twin Pregnancy With Antenatal Problem | Twin Pregnancy, Antepartum Condition or Complication | Twin Dichorionic Diamniotic Placenta | Twin Monochorionic Monoamniotic Placenta | Twin; Pregnancy, Affecting Fetus or Newborn | Prenatal Disorder

Belgium, Canada, Germany, Israel, Spain, United Kingdom
University of Liverpool
Imperial College London; Liverpool Women's NHS Foundation Trust

Recruiting

Is the Vaginal Microbiome and Metabolome Associated With Spontaneous Preterm Birth (sPTB) in Multiple Pregnancies? (SPRUCE)

Preterm Birth | Preterm Labor | Twin Dichorionic Diamniotic Placenta | Twin Monochorionic Monoamniotic Placenta | Vaginal Microbiome | Cervical Stiffness | Twin; Pregnancy, Affecting Fetus or Newborn | Multiple; Pregnancy, Complicated

United Kingdom
St George's, University of London

Unknown

Emergency Cerclage in Twin Pregnancies at Imminent Risk of Preterm Birth: an Open-Label Randomised Controlled Trial (ENCIRCLE)

Preterm Birth | Twin Pregnancy With Antenatal Problem | Twin to Twin Transfusion Syndrome

United Kingdom
Seattle Children's Hospital

Recruiting

Laser Photocoagulation of Communicating Vessels in Twin-to-Twin Transfusion Syndrome

Monochorionic Diamniotic Placenta | Twin to Twin Transfusion as Antepartum Condition

United States
University of North Carolina, Chapel Hill
National Institute of Mental Health (NIMH)

Completed

Early Brain Development in Twins

Twin Brain Development

United States
Universitaire Ziekenhuizen KU Leuven
University of Pittsburgh; Sheba Medical Center; Mount Sinai Hospital, Canada; Leiden... and other collaborators

Unknown

TRAP Intervention STudy: Early Versus Late Intervention for Twin Reversed Arterial Perfusion Sequence (TRAPIST)

Twin Reversal Arterial Perfusion Syndrome

Spain, Germany, Israel, Belgium, Netherlands, Canada, United States, Austria, France, Italy, United Kingdom
Eunice Kennedy Shriver National Institute of Child...
Children's Hospital Medical Center, Cincinnati

Unknown

Fetoscopic Selective Laser Photocoagulation in Twin-Twin Transfusion Syndrome

Twin to Twin Transfusion Syndrome

United States
University of Tennessee
Regional Medical Center, Regional One Health

Completed

Laser Photocoagulation in Twin to Twin Transfusion Syndrome (TTTS)

Twin to Twin Transfusion Syndrome

United States
University of Miami

Recruiting

Database of Monochorionic Pregnancies

Twin to Twin Transfusion Syndrome | Twin; Complicating Pregnancy | Twin Reversal Arterial Perfusion Syndrome | Monochorionic Diamniotic Placenta | Monochorial Monoamniotic Placenta

United States
Leiden University Medical Center
Karolinska University Hospital; Universitaire Ziekenhuizen KU Leuven; Boston... and other collaborators

Recruiting

Selective Fetal Growth Restriction in Monochorionic Twins - an International Investigation (CONTRAST)

Fetal Growth Retardation | Twin; Pregnancy, Affecting Fetus or Newborn | Twin Diseases | Twin Monochorionic Diamniotic Placenta

United States, Belgium, Netherlands, Sweden, Canada, Spain
University of South Florida

Completed

Selective Laser Photocoagulation of Communicating Vessels in Twin-Twin Transfusion Syndrome (TTTS)

Twin Twin Transfusion Syndrome

United States
University of Southern California

Active, not recruiting

Sequential vs. Standard Laser Treatment of Twin-twin Transfusion Syndrome

Twin Twin Transfusion Syndrome

United States
Jimmy Espinoza

Not yet recruiting

The Efficacy of the KARL STORZ Curved Fetoscope and Straight Fetoscope for Laser Photocoagulation of Placental Anastomoses

Twin to Twin Transfusion Syndrome

United States
Boston Children's Hospital

Not yet recruiting

A Prospective Study on the Role of Karl Storz Curved and Straight Fetoscopes (11508AAK and 11506AAK) for Fetoscopic Intrauterine Procedures

Pregnancy Related | Maternal; Procedure | Fetal Conditions | Twin Monochorionic Monoamniotic Placenta | Twin to Twin Transfusion Syndrome | Twin Reversal Arterial Perfusion Syndrome | Vasa Previa | In Utero Procedure Affecting Fetus or Newborn | Chorion; Abnormal | Chorioangioma

United States
Columbia University

Completed

Renal Artery Dopplers in Twin Twin Transfusion Syndrome

Twin Twin Transfusion Syndrome

United States
Catherine Cibulskis, MD
St. Louis University

Active, not recruiting

The Utility of MRI Scoring to Predict Neurodevelopmental Outcomes in Survivors of Twin-to-Twin Transfusion Syndrome

Fetofetal Transfusion

United States
Natera, Inc.

Recruiting

Clinical Utility of the Addition of a SNP-based NIPT Zygosity Determination in Twin Pregnancy Management. (ZTWINS)

Pregnancy Complications | Twin to Twin Transfusion Syndrome | Multiple Gestation; Maternal Care

United States
St. Louis University

Terminated

Cerclage for Short Cervix in Twins

Short Cervix, Twins

United States
Stanford University

Completed

Understanding and Diagnosing Allergic Disease in Twins

Allergies

United States
Leiden University Medical Center

Recruiting

The TAPS Trial - Fetoscopic Laser Surgery for Twin Anemia Polycythemia Sequence

Twin Anemia Polycythemia Sequence

United States, Italy, Netherlands, Spain, Sweden
Michael A Belfort
Baylor College of Medicine

Not yet recruiting

Safety and Efficacy of Fetoscopes Used in Fetoscopic Selective Laser Photocoagulation

Twin Monochorionic Diamniotic Placenta

United States
TriHealth Inc.

Completed

Fetal Lung Maturation in Twin Gestations

Discordance in Lung Maturity in Diamniotic Twins

United States
University of Edinburgh
NHS Lothian

Completed

An Open Randomised Trial of the Arabin Pessary to Prevent Pre-term Birth in Twin Pregnancy (STOPPIT-2)

Twin Pregnancy With Antenatal Problem

Belgium, United Kingdom
Children's Oncology Group
National Cancer Institute (NCI)

Recruiting

Somatic Mosaicism in Twins Discordant for Childhood Cancer

Central Nervous System Tumor | Somatic Mutation | Pediatric Central Nervous System Tumor | Discordant Twin

United States
Mayo Clinic

Terminated

Automated Myocardial Performance Index Using Samsung HERA W10

Congenital Diaphragmatic Hernia | Neural Tube Defects | Twin to Twin Transfusion Syndrome | Lower Urinary Tract Infection

United States
Thomas Jefferson University
Federico II University

Recruiting

Cerclage for Twins With Short Cervical Length ≤ 15mm (TWIN-UIC)

Preterm Birth | Twin Pregnancy With Antenatal Problem | Short Cervix

United States, Egypt, Italy, Spain
Medical College of Wisconsin
National Heart, Lung, and Blood Institute (NHLBI); University of Wisconsin,... and other collaborators

Recruiting

Fetal Electrophysiologic Abnormalities in High-Risk Pregnancies Associated With Fetal Demise

Sudden Infant Death | Congenital Heart Disease | Pregnancy Loss | Gastroschisis | Fetal Death | Brugada Syndrome | High Risk Pregnancy | Stillbirth | Long QT Syndrome | Fetal Demise | Birth Defect | Twin Monochorionic Monoamniotic Placenta | Twin Twin Transfusion Syndrome | Fetal Hydrops | Fetal Arrhythmia | Intrauterine... and other conditions

United States
Columbia University

Recruiting

Prophylactic Methylergonovine for Twin Cesarean

Postpartum Hemorrhage | Twin; Complicating Pregnancy

United States
Kemin Foods LC
DSM Nutritional Products, Inc.

Terminated

Effects of Lutein on Visual Function

Healthy | Nutrition Poor

United Kingdom
Mead Johnson Nutrition

Withdrawn

Evaluation of Fatty Acid Levels and Growth in Infants Fed Amino Acid Based (AA) Formulas

Cow's Milk Allergy | Intolerance to Extensively Hydrolyzed Formulas | Intolerance to Breast Milk

United Kingdom
Thomas Jefferson University
University Hospital, Geneva; University of Bologna; Columbia University; Federico... and other collaborators

Terminated

Physical Exam Indicated Cerclage in Twin Gestations (TWIN-PEIC)

Preterm Birth | Twin Pregnancy, Antepartum Condition or Complication | Cervical Dilation Premature

United States, Italy, Poland
University of Alabama at Birmingham

Recruiting

Gain of Keratinized Mucosa Around Teeth and Dental Implants Using a Combination of Strip Gingival Graft and Acellular Dermal Matrix

Gingival Recession | Thin Gingiva | Lack of Keratinized Attached Peri-implant Mucosa

United States
Imperial College London

Enrolling by invitation

Smart Watch Insights for Prevention of Exacerbations and Enhance Rehabilitation - Movement Study (SWIPER-MOVES)

Cardiovascular Diseases | Diabetes | Respiratory Disease | Non-Alcoholic Fatty Liver Disease

United Kingdom
Mannkind Corporation

Completed

A Study Designed to Determine if the Drugs Albuterol (Salbutamol) and Fluticasone Have an Effect on the Pharmacokinetics of the Investigational Product Technosphere® Insulin Inhalation Powder in Healthy Volunteers

Diabetes Mellitus | Healthy Subjects

United Kingdom
Prexton Therapeutics

Completed

A Phase I, Double Blind, Placebo Controlled, First in Human, Single and Multiple Ascending Oral Dose, Safety, Tolerability and Pharmacokinetic Study in Healthy Male and Female Subjects

Parkinson's Disease

United Kingdom
Natera, Inc.

Completed

Verification of Risk Assignment for Whole Chromosome Using SNP-based NIPT in Vanishing Twin Pregnancies (VANISH)

Trisomy 21 | Trisomy 18 | Trisomy 13 | Vanishing Twin

United States
Moorfields Eye Hospital NHS Foundation Trust

Completed

Advanced OCT and Adaptive Optics Imaging in Retinal Disease (The ACAD Study) (ACAD)

Retinal Diseases | Vitreous Diseases | Choroidal Diseases

United Kingdom
University of Oxford
Merck Sharp & Dohme LLC

Completed

Treatment of HDL to Reduce the Incidence of Vascular Events HPS2-THRIVE (HPS2-THRIVE)

Cardiovascular Disease | Diabetes Mellitus | Peripheral Arterial Disease | Coronary Heart Disease

United Kingdom
University of Leicester

Recruiting

Usability and Acceptability Study of the P-STEP Mobile Application

Heart Failure | Chronic Obstructive Pulmonary Disease | Asthma | Type 2 Diabetes | Coronary Heart Disease | Interstitial Lung Disease

United Kingdom
AstraZeneca
Parexel

Recruiting

AZD7798 Safety, Tolerability, and Pharmacokinetics After a Single Ascending and Repeat Dose Administrations to Healthy Subjects, and Patients With Crohn's Disease

Healthy Subjects | Crohns Disease

United Kingdom
University of Hull

Recruiting

PREhabilitation in Patients Awaiting Acute Inpatient Cardiac SurgEry ((PREP-ACE))

Coronary Artery Disease | Aortic Valve Disease | Endocarditis | Cardiac Disease | Valve Heart Disease

United Kingdom
Guy's and St Thomas' NHS Foundation Trust

Completed

The Role of HNHF to Improve Clinical Outcomes Following Severe AECOPD

Chronic Obstructive Pulmonary Disease

United Kingdom
Guy's and St Thomas' NHS Foundation Trust

Completed

NRD to Predict COPD Exacerbations at Home

Chronic Obstructive Pulmonary Disease

United Kingdom
Philips Respironics

Completed

Evaluating Forced Oscillation Technique (FOT) in Abolishing Flow Limitation

Chronic Obstructive Pulmonary Disease

United Kingdom
GlaxoSmithKline
University of Cambridge

Completed

Effects Of Oral Prednisolone On Bone Metabolism In Patients With Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease

United Kingdom
King's College London

Completed

The Feasibility of Following the Crohn's Diet

Inflammatory Bowel Diseases | Crohn Disease | Dietary Modification

United Kingdom
King's College Hospital NHS Trust
University of Brighton

Completed

The Effects of a Home Exercise Video Programme for Patients With COPD

Chronic Obstructive Pulmonary Disease (COPD)

United Kingdom
University of Leeds
The Leeds Teaching Hospitals NHS Trust

Recruiting

Evaluating Treatable Traits Across the Spectrum of Chronic Obstructive Airways Disease

Airway Disease

United Kingdom
University of Edinburgh

Not yet recruiting

Innate Immunity in COPD

Chronic Obstructive Pulmonary Disease

United Kingdom
Imperial College London

Withdrawn

Endotoxin and Inflammatory Markers in Healthy Non-Smokers and Current Smokers Including Patients With Chronic Obstructive Pulmonary Disease (COPD)

Chronic Obstructive Pulmonary Disease

United Kingdom

Clinical Trials on Twin Diseases in United Kingdom

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