- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT01613885
Understanding and Diagnosing Allergic Disease in Twins
March 15, 2021 updated by: Kari Christine Nadeau, MD, PhD, Stanford University
The purpose of this study is to gain better understanding of how the immune system works in twins with and without allergic disease.
Healthy volunteers are not specifically targeted.
Healthy non-allergic study participants may be found through the course of evaluation for the presence of allergies.
Study Overview
Detailed Description
The purpose of this study is to study the genetic control and gain better understanding of how the immune system works in twins with and without allergic disease.
Although healthy volunteers are not specifically targeted, they might be identified when non-allergic study participants are found through the course of evaluation for the presence of allergies.
Study Type
Observational
Enrollment (Actual)
340
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
-
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California
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Stanford, California, United States, 94305
- Stanford University School of Medicine
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Stanford, California, United States, 94305
- Sean N Parker Center for Allergy and Asthma Research at Stanford
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Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
1 second to 80 years (Child, Adult, Older Adult)
Accepts Healthy Volunteers
Yes
Genders Eligible for Study
All
Sampling Method
Non-Probability Sample
Study Population
Healthy volunteers are not specifically targeted.
Healthy non-allergic study participants may be found through the course of evaluation for the presence of allergies.
Women, minorities or children will not be excluded from this study.
Description
Inclusion Criteria:
- Twin participants ages 0 to 80 years who are with or without allergy disease.
Exclusion Criteria:
- Patients with special risks attendant to venipuncture will be excluded.
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
Cohorts and Interventions
Group / Cohort |
Intervention / Treatment |
---|---|
Twins
Twins that are ages 0 to 80 years, with or without allergy disease.
|
This study does not involve any intervention other than obtaining blood, nasal/cheek/throat/skin swabs, saliva, sputum, urine, and stool samples, breathing and skin tests.
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
Comparing immune systems of food allergic twins
Time Frame: 2 years
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Differences in genetic and phenotypic characteristics between twin siblings
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2 years
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Sponsor
Publications and helpful links
The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start (Actual)
August 1, 2010
Primary Completion (Actual)
October 1, 2019
Study Completion (Actual)
October 1, 2019
Study Registration Dates
First Submitted
June 5, 2012
First Submitted That Met QC Criteria
June 5, 2012
First Posted (Estimate)
June 7, 2012
Study Record Updates
Last Update Posted (Actual)
March 17, 2021
Last Update Submitted That Met QC Criteria
March 15, 2021
Last Verified
March 1, 2021
More Information
Terms related to this study
Additional Relevant MeSH Terms
Other Study ID Numbers
- SU-10042011-8546
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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