Clinical Trials on Tyrosine Kinase Inhibitor

Total 662 results

Ankara City Hospital Bilkent

Completed

The Effect of Using Preendoscopic Proton Pump Inhibitors in Upper Gastrointestinal System Bleeding on Patient Prognosis

Upper Gastrointestinal Bleeding, Proton Pump Inhibitors

Turkey
Stanford University

Completed

Empagliflozin in Diuretic Refractory Ascites (DRAin-Em 01)

Liver Cirrhosis | Cirrhosis | Ascites | Ascites Hepatic | Sodium-Glucose Transporter 2 Inhibitors

United States
Duke University
David Grant U.S. Air Force Medical Center

Completed

Genetically Guided Statin Therapy

Hypercholesterolemia | Hydroxy-methylglutaryl-coenzyme A (HMG Co-A) Reductase Inhibitors Adverse Reaction

United States
Sun Yat-sen University

Recruiting

HAIC Combined With Lenvatinib and PD-1 Inhibitor in Infiltrative Hepatocellular Carcinoma

Hepatocellular Carcinoma | PD-1 Inhibitor | Lenvatinib | Hepatic Arterial Infusion Chemotherapy

China
Novo Nordisk A/S

Completed

Non-Interventional Study of NovoSeven® Used in Patients With Haemophilia A and B With Inhibitors When Undergoing Surgery

Congenital Bleeding Disorder | Haemophilia A With Inhibitors | Haemophilia B With Inhibitors

Japan
Novo Nordisk A/S

Completed

Safety and Tolerability of Intravenous Doses of Activated Recombinant Human Factor VII in Healthy Volunteers

Healthy | Congenital Bleeding Disorder | Haemophilia A With Inhibitors | Haemophilia B With Inhibitors

France
Novo Nordisk A/S

Completed

High Dose of Activated Recombinant Human Factor VII for Treatment of Mild/Moderate Joint Bleeds in Haemophilia Patients With Inhibitors

Congenital Bleeding Disorder | Haemophilia A With Inhibitors | Haemophilia B With Inhibitors

France, United Kingdom, Spain, Israel, Poland, Turkey, Hungary
Novo Nordisk A/S

Completed

Prediction of the Efficacy of Activated Recombinant Human Factor VII in Adult Congenital Haemophilia A or B Patients With Inhibitors by Use of Thromboelastography

Congenital Bleeding Disorder | Haemophilia A With Inhibitors | Haemophilia B With Inhibitors

United States, Denmark, France, United Kingdom
Peking Union Medical College Hospital

Recruiting

Regorafenib Combined With PD-1 Inhibitor Therapy for Second-line Treatment of Hepatocellular Carcinoma

Hepatocellular Carcinoma | PD-1 Inhibitor | Regorafenib

China
Tianjin Chest Hospital

Recruiting

Effect of Evolocumab Added to Moderate-Intensity Statin Therapy on LDL-C Lowering and Cardiovascular Adverse Events in Patients With Acute Coronary Syndrome (EMSIACS)

Acute Coronary Syndrome | Proprotein Convertase Subtilisin/Kexin Type 9 Inhibitor

China
Funch-Jensen, Peter, M.D., D.M.Sc.
Medtronic - MITG

Completed

Pain Relieving Efficacy of TAP Block in Patients After Laparoscopic Gastric Bypass.

Pain | Obesity | Surgery | Neuromuscular Inhibition

Denmark
RenJi Hospital

Recruiting

Bladder Sparing Treatment of Tislelizumab, Gemcitabine and Cisplatin for Patients With PD-L1 Positive Muscle Invasive Bladder Cancer

Urothelial Carcinoma Bladder | PD-1 Inhibitor

China
University Hospital, Brest

Completed

Thyroid Dysfunction and Nivolumab Reponse in NSCLC (THYRONIVO)

Non Small Cell Lung Cancer Metastatic | Prognosis | Thyroid Dysfunction | Immune Checkpoint Inhibitor | Treatment Adverse Effect

France
University Hospital, Bordeaux

Recruiting

AntiPlatelet theraPy stratEgy followiNg Left Atrial appenDAGe closurE (APPENDAGE)

Stroke | Atrial Fibrillation | Anticoagulants | Platelet Aggregation Inhibitors | Atrial Appendage

France
Hoffmann-La Roche

Completed

An Observational Study to Evaluate Physical Activity, Bleeding Incidence and Health Related Quality of Life, in Participants With Haemophilia A Without Inhibitors Receiving Standard of Care Treatment (POWER)

Haemophilia A | Moderate Hereditary Factor VIII Deficiency Disease Without Inhibitor | Severe Hereditary Factor VIII Deficiency Disease Without Inhibitor

Italy
Universidade Estadual Paulista Júlio de Mesquita...

Completed

Combined Training on Body Composition of Postmenopausal Women Undergoing Treatment for Breast Cancer

Breast Cancer | Aromatase Inhibitors | Postmenopausal
First People's Hospital of Hangzhou

Not yet recruiting

The Efficacy of Chemotherapy Combined With Immunocheckpoint Inhibitors in Advanced Biliary Malignancies

Biliary Tract Cancer | Gemcitabine | Immune Checkpoint Inhibitors

China
Washington University School of Medicine

Terminated

Treatment of Angiotensin Converting Enzyme Inhibitor-induced Angioedema

Angioedema Caused by Angiotensin-Converting-Enzyme Inhibitor

United States
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Recruiting

Correlation Between Pre-transplant ICI Exposure and Post-transplant Graft Rejection

Hepatocellular Carcinoma | Graft Rejection | Immunotherapy | Immune Checkpoint Inhibitor

China
National Liver Institute, Egypt

Completed

Proton Pump Inhibitors in Cirrhotic Patients

Liver Cirrhosis | Proton Pump Inhibitor Adverse Reaction

Egypt
Mansoura University

Active, not recruiting

A Randomized Trial to Evaluate Efficacy and Safety of Intracavernosal Injection of Platelet-Rich Plasma Versus Phosphodiesterase Type-5 Inhibitors for Treatment of Erectile Dysfunction.

Erectile Dysfunction Following Radiation Therapy | Phosphodiesterase Inhibitor Adverse Reaction | Platelet- Rich Plasma (PRP)

Egypt
Catherine Buettner
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

Completed

Clinical Trial of CoQ10 for Mild-to-Moderate Statin-Associated Muscle Symptoms

Pain | Weakness | HMG COA Reductase Inhibitor Adverse Reaction | Cramps | Myalgia or Myositis Nos

United States
Universidad de Almeria

Completed

Effect of Biodanza on Desire, Excitation and Sexual Inhibition

Sexual Arousal Disorder | Sexual Desire Disorder | Sexual Inhibition

Spain
Ruijin Hospital

Withdrawn

Proton Pump Inhibitor Prevent Dual Antiplatelet Agents Induced Gastrointestinal Ulcer After Coronary Artery Bypass Graft (DACAB-GI-2)

Gastric Ulcer Induced by Antiplatelet Agent | Ulcer of the Gastrointestinal Tract | Proton Pump Inhibitor

China
Takeda

Completed

A Study to Determine Progression-free Survival (PFS) and Evaluate Participant Experience for Participants With Metastatic Anaplastic Lymphoma Kinase-positive (ALK+) Non-Small Cell Lung Cancer (NSCLC) Treated With Anaplastic Lymphoma Kinase (ALK) Inhibitors

Carcinoma Non-small-cell Lung | Anaplastic Lymphoma Kinase-positive

United States
Novo Nordisk A/S

Completed

Epidemiological Study on Haemophilia Care and Orthopaedic Status in Developing Countries (HAEMOcare)

Congenital Bleeding Disorder | Haemophilia A With Inhibitors | Haemophilia B With Inhibitors | Haemophilia A | Haemophilia B

India, Morocco, South Africa, Oman
Novo Nordisk A/S

Completed

Observational Patient Diary Study of Treatment Doses for Patients With Haemophilia With Inhibitors to Factors VIII and IX (DOSE)

Congenital Bleeding Disorder | Haemophilia A With Inhibitors | Haemophilia B With Inhibitors

United States
Novo Nordisk A/S

Completed

A Trial Investigating the Pharmacokinetics and Pharmacodynamics of rFVIIa in Patients With Haemophilia A or B With or Without Inhibitors

Congenital Bleeding Disorder | Haemophilia A With Inhibitors | Haemophilia B With Inhibitors | Haemophilia A | Haemophilia B

Spain
University of Bern

Recruiting

Differences Between Suicide Attempters and Suicide Ideators. Influence of the Brief Therapy Attempted Suicide Short Intervention Program (ASSIP) on Neuropsychological Correlates and Psychological Process Factors - Project 2 (NePsyAssip HT)

Suicide, Attempted | Self Efficacy | Suicide Ideation | Locus of Control | Inhibitory Control | Process Factors | Movement Synchrony

Switzerland
University Hospital, Montpellier
CryoMed Millenaire

Recruiting

Assessment of Cryotherapy's Analgesic Impact in Anti-aromatase-induced Arthralgia (CRYOMATASE)

Breast Cancer | Aromatase Inhibitors

France
Creighton University

Terminated

Vitamin D Replacement: The Effect on Statin-Related Myalgias

HMG-CoA Reductase Inhibitors-related Myalgias

United States
Yonsei University
CanariaBio Inc.

Recruiting

Oregovomab and PLD in PARP Inhibitor Resistant Ovarian, Fallopian Tube, or Primary Peritoneal Cancer Patients Not Candidate for Platinum Retreatment

PARP Inhibitor Resistant Ovarian, Fallopian Tube, or Primary Peritoneal Cancer Patients Not Candidate for Platinum Retreatment

Korea, Republic of
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
First Affiliated Hospital of Jinan University; Shenzhen University General...

Recruiting

Pemigatinib Combined With PD-1 Inhibitor in Unresectable or Metastatic Intrahepatic Cholangiocarcinoma

Carcinoma | Digestive System Neoplasms | Intrahepatic Cholangiocarcinoma | First-line Treatment | PD-1 Inhibitor

China
Hippocration General Hospital

Completed

Pleiotropic Effects of Atorvastatin in High Cardiovascular Risk Patients

Coronary Artery Disease | Atherosclerosis | Endothelial Dysfunction | Oxidative Stress | HMG-CoA Reductase Inhibitor Toxicity

Greece
HaEmek Medical Center, Israel

Completed

Prepulse Inhibition (PPI) of Startle Reflex in Schizophrenia Patients Related to Type of Treatment and Illness Duration

Schizophrenia | Medication Adherence | Inhibition (Psychology)

Israel
G.Gennimatas General Hospital
2nd Department of Cardiology, "Attikon" University Hospital, National and...

Not yet recruiting

Dapagliflozin to Prevent the Incidence of Contrast Induced Nephropathy After Heart Catheterization and Percutaneous Coronary Intervention

Acute Kidney Injury | Percutaneous Coronary Intervention | Left Cardiac Catheterization | Sodium-glucose Co-transporter 2 Inhibitors

Greece
Peking Union Medical College Hospital

Recruiting

irAE Prediction of Anti-PD-1/L1 in Lung Cancer

Lung Cancer | Immune Checkpoint Inhibitors

China
Peking University

Unknown

Phase I/II Clinical Study of Decitabine Combined With TQB2450 Injection or Decitabine + Anlotinib Combined With TQB2450 Injection in the Treatment of PD-1 Monoclonal Antibody-resistant Digestive System Tumors

Patients With Digestive System Tumors Resistant to PD-1 Inhibitors
University Hospital, Gentofte, Copenhagen

Completed

The Effect of HMG-CoA Reductase Inhibition on Postprandial GLP-1 Secretion

Diabetes Mellitus, Type 2 | Hydroxymethylglutaryl-CoA Reductase Inhibitors

Denmark
Peking Union Medical College Hospital
Betta Pharmaceuticals Co., Ltd.

Recruiting

A Real World Study of Ensartinib in Advanced ALK-positive NSCLC

Carcinoma, Non-Small-Cell Lung | Anaplastic Lymphoma Kinase I1171N | Ensartinib

China
Fudan University

Recruiting

Tislelizumab Combing Chemoradiotherapy in Recurrent Cervical Cancer

Cervical Cancer | Chemoradiotherapy | Immune Checkpoint Inhibitor

China
Federation Francophone de Cancerologie Digestive

Recruiting

Study to Evaluate Efficacy and Safety of Selective Internal Radiation Therapy Plus Xelox, Bevacizumab and Atezolizumab (Immune Chekpoint Inhibitor) in Patients With Liver-dominant Metastatic Colorectal Cancer (SIRTCI)

Metastatic Colorectal Cancer | MSS | pMMR | Immune Checkpoint Inhibitor | Internal Radiotherapy

France
University Hospital, Caen

Completed

Delirium Related to Proton Pump Inhibitors Use

Delirium | Hyponatremia | Proton Pump Inhibitor Adverse Reaction

France
Novo Nordisk A/S

Completed

A Long-term Assessment of Physical Activity, Range of Motion, and Functional Status Following Elective Orthopedic Surgery in Hemophilia Patients With Inhibitors

Congenital Bleeding Disorder | Haemophilia A With Inhibitors | Haemophilia B With Inhibitors

United States
Novo Nordisk A/S

Completed

Non-Interventional Study of NovoSeven® Used in Patients With Haemophilia A and B With Inhibitors Under Normal Clinical Practice

Congenital Bleeding Disorder | Haemophilia A With Inhibitors | Haemophilia B With Inhibitors

Japan
Novo Nordisk A/S

Completed

Observational Registry of NovoSeven® Used as On-demand Treatment of Bleeds in Patients With Haemophilia A and B With Inhibitors (ONE)

Congenital Bleeding Disorder | Haemophilia A With Inhibitors | Haemophilia B With Inhibitors

Saudi Arabia, Algeria, Turkey, Germany, Poland, Netherlands, Italy, Belgium, South Africa, United Kingdom, Sweden, Austria, Portugal, France, Czech Republic, Venezuela
Sichuan University

Recruiting

Safety and Tolerability of Low Dose Radiotherapy Concurrent SBRT and PD-1 Inhibitors in Advanced NSCLC.

NSCLC | PD-1 Inhibitor | Stereotactic Body Radiotherapy | Low Dose Radiotherapy

China
Trabzon Arakli Bayram Halil Public Hospital

Recruiting

Asymptomatic Bacteriuria, Urinalysis Abnormality at the Initiation of SGLT2 Inhibitors and UTI Risk

Type2diabetes, SGLT2 Inhibitor, Urinary Tract Infection

Turkey
University Hospital, Grenoble
University Hospital, Rouen; University Hospital, Paris

Recruiting

Bradykinin-degradating Enzymes Activities in Angiotensin-Converting Enzyme Inhibitors-associated Angioedema (KIN-ACE)

Angio-Oedema Caused by Angiotensin-Converting-Enzyme Inhibitor

France
Ascension Healthcare Development Limited

Recruiting

A Pharmacokinetic and Clotting Activity Study of FVIII-PEGLip

Hemophilia A With Inhibitor

Russian Federation

Clinical Trials on Tyrosine Kinase Inhibitor

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