Clinical Trials on Undertreatment of Hypercholesterolaemia

Total 27685 results

AstraZeneca

Completed

Centralized Pan-South African Survey on the Undertreatment of Hypercholesterolaemia (CEPHEUS)

Undertreatment of Hypercholesterolaemia

South Africa
Sanofi
Regeneron Pharmaceuticals

Completed

Usability Study of the Commercial Auto-injector Device and the New Auto-injector Device (SYDNEY) in Patients With High or Very High CV Risk With Hypercholesterolemia Not Adequately Controlled With Their Lipid-Modifying Therapy

Hypercholesterolaemia

United States
GlaxoSmithKline

Completed

Acotral® Versus Zetia® Ezetimibe Bioequivalance Study.

Hypercholesterolaemia

India
AstraZeneca

Completed

Registry On Efficacy and Safety Of Rosuvastatin, and Atorvastatin and Simvastatin In Hypercholesterolaemia

Hypercholesterolaemia

Singapore
AstraZeneca

Completed

PULSAR - A Prospective Study to Evaluate the Utility of Low Doses of the Statins Atorvastatin and Rosuvastatin.

Hypercholesterolaemia
Akeso
AD Pharmaceuticals Co., Ltd.

Completed

A Study of PCSK9 Inhibitor AK102 in Healthy Subjects

Hypercholesterolaemia

China
GlaxoSmithKline

Completed

Rosuvastatin Calcium Bioequivalence Study - Fast

Hypercholesterolaemia

Brazil
AstraZeneca

Completed

Evaluation of Patients Treated With HMG-CoA Reductase Inhibitors to Reach Cholesterol Target Values

Hypercholesterolaemia

Bosnia and Herzegovina
AstraZeneca

Completed

Non-interventional Study (NIS) to Assess Reaching of Cholesterol Target Values in Patients Treated With HMG-CoA Reductase Inhibitors

Hypercholesterolaemia

Croatia
AstraZeneca

Completed

Rosuvastatin Efficacy and Safety Evaluation in Hypercholesterolaemic Patients (RESEARCH)

Hypercholesterolaemia

Greece
AstraZeneca

Completed

OLE Study to Evaluate Safety / Efficacy of ZD4522

Hypercholesterolaemia
Novartis Pharmaceuticals

Recruiting

Specified Drug-use Survey of Leqvio for s.c. Injection.

Hypercholesterolaemia | Familial Hypercholesterolaemia

Japan
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

Carotid Atorvastatin Study in Hyperlipidemic Post-Menopausal Women

Hypercholesterolaemia

France, Belgium, Netherlands
AstraZeneca

Terminated

Study of Asian Patients With Hypercholesterolaemia in the UK - Rosuvastatin 5mg Versus Atorvastatin 10mg

Hypercholesterolaemia

United Kingdom
Amgen

Terminated

Study to Evaluate the Safety of Repatha® in Pregnancy

Pregnancy | Hypercholesterolaemia

Belgium, Denmark, Italy, Czechia, United Kingdom, Australia, Austria, Greece, Switzerland, Netherlands, Spain, Sweden, Slovakia, Norway
AstraZeneca

Withdrawn

ORBITAL: Open-Label Primary Care Study: Rosuvastatin Based Compliance Initiatives Linked To Achievement Of LDL Goals

Primary Hypercholesterolaemia
Amgen

Completed

Chart Review of Repatha® in Subjects With Hyperlipidaemia (HEYMANS)

Hypercholesterolaemia

Austria, Italy, Belgium, Czechia, Switzerland, Spain, Slovakia, Germany, Portugal, Greece, Bulgaria, Sweden
Novo Nordisk A/S

Completed

A Research Study Investigating How NNC0385-0434 is Tolerated in People With or Without High Cholesterol Levels

Healthy Volunteers | Hypercholesterolaemia

United Kingdom
Organon and Co

Completed

TWICE (Ezetimibe Together With Any Statin Cholesterol Enhancement)(0653-060)

Hypercholesterolaemia | Hyperlipidaemia
Lescuyer Laboratory
BioFortis

Completed

Dose Effect of Limicol on (LDL)-Cholesterol Levels

Hypercholesterolaemia

France
Universiteit Antwerpen

Completed

The Effect of a Red Rice and Olive Extract Nutrition Supplement on Cholesterol Levels in Patients With Metabolic Syndrome

Hypercholesterolaemia

Belgium
AstraZeneca

Completed

Evaluation of the Efficacy and Safety of Rosuvastatin 5 mg Versus Pravastatin 40 mg and Atorvastatin 10 mg in Type IIa and IIb Hypercholesterolaemic Patients (CAP-Chol)

Type IIa and IIb Hypercholesterolaemia

France
Shanghai Junshi Bioscience Co., Ltd.

Not yet recruiting

Efficacy and Safety of JS002 as Monotherapy in Patients With Primary Hypercholesterolaemia and Mixed Dyslipidemia

Primary Hypercholesterolaemia and Mixed Dyslipidemia

China
Radboud University Medical Center
Merck Sharp & Dohme LLC

Completed

Pharmacokinetic Drug Interaction Study Between Raltegravir and Atorvastatin. (AVIATOR)

HIV | Hypercholesterolaemia

Netherlands
Sanofi
Regeneron Pharmaceuticals

Completed

Efficacy and Safety of Alirocumab Versus Placebo on Top of Maximally Tolerated Lipid Lowering Therapy in Patients With Hypercholesterolemia Who Have Type 1 or Type 2 Diabetes and Are Treated With Insulin (ODYSSEY DM - Insulin)

Hypercholesterolaemia

Belgium, Spain, Germany, Austria, Italy, United States, France, Netherlands, Switzerland, United Kingdom
Juan A. Arnaiz

Completed

Treatment With Rosuvastatin Versus Switching PI (Protease Inhibitor) in Patients HIV With High Cholesterol Levels (SOS)

HIV | Hypercholesterolaemia

Spain
Danone Research

Completed

Pilot Study in the Cholesterol Absorption Reduction After Consumption of Low-fat, Drinkable Fermented Milk Enriched With Plant Sterols

Mildly Hypercholesterolemic Subjects

Canada
Danone Research

Completed

Effects of Fermented Milk Product Enriched With Plant Sterols and Policosanols in Mild Hypercholesterolaemic Adults

Mildly Hypercholesterolemic Subjects

United Kingdom
Danone Research

Completed

Effect of the Consumption of a Fermented Milk Enriched With Plant Sterols (Italy)

Mildly Hypercholesterolemic Subjects

Italy
Merck Sharp & Dohme LLC

Completed

MK-0616 (Oral PCSK9 Inhibitor) Renal Impairment Study 2 (MK-0616-020)

Hypercholesterolaemia

United States
Sanofi
Regeneron Pharmaceuticals

Completed

An Efficacy and Safety Study of Alirocumab in Children and Adolescents With Heterozygous Familial Hypercholesterolemia

Hypercholesterolaemia

Czechia, France, Denmark, Netherlands, Austria, Mexico, Spain, United States, Argentina, Brazil, Bulgaria, Canada, Finland, Hungary, Italy, Lebanon, Norway, Poland, Russian Federation, Slovenia, South Africa, Sweden, Taiwan, Turkey
Sanofi
Regeneron Pharmaceuticals

Completed

An 8-Week Dose-Finding Study to Evaluate the Efficacy and Safety of Alirocumab in Children and Adolescents With Heterozygous Familial Hypercholesterolemia (ODYSSEY KIDS)

Hypercholesterolaemia

Norway, Russian Federation, Sweden, South Africa, Czechia, United States, Canada, France, Netherlands, Spain
Sanofi
Regeneron Pharmaceuticals

Completed

Efficacy and Safety of Alirocumab (SAR236553/REGN727) Versus Placebo on Top of Lipid-Modifying Therapy in Patients With Heterozygous Familial Hypercholesterolemia (ODYSSEY HIGH FH)

Hypercholesterolaemia

Netherlands, United States, Canada, Russian Federation, South Africa
Institute of Health Information and Statistics...
Centre of Cardiovascular and Transplantation Surgery, Czech Republic; The Central... and other collaborators

Recruiting

Pilot Project of Familial Hypercholesterolemia Screening in Newborns in the Czech Republic (CzeCH-IN)

Familial Hypercholesterolaemia

Czechia
Fundación Hipercolesterolemia Familiar
Instituto de Salud Carlos III; Fundación Centro Nacional de Investigaciones...

Recruiting

The Spanish Familial Hypercholesterolaemia Cohort Study (SAFEHEART)

Familial Hypercholesterolaemia

Spain
University of Ljubljana, Faculty of Medicine
University Medical Centre Ljubljana; Kinderkrankenhaus auf der Bult

Completed

Universal Familial Hypercholesterolemia Screening in Children

Familial Hypercholesterolemia | Polygenic Hypercholesterolaemia

Germany, Slovenia
Amryt Pharma

Active, not recruiting

Efficacy and Safety of Lomitapide in Paediatric Patients With Homozygous Familial Hypercholesterolaemia (HoFH)

Homozygous Familial Hypercholesterolaemia (HoFH)

Germany, Israel, Italy, Saudi Arabia, Spain, Tunisia
AstraZeneca

Completed

An Study to Evaluate Rosuvastatin in Children and Adolescents With Familial Hypercholesterolaemia

Familial Hypercholesterolaemia

United States, Netherlands, Norway, Canada, Belgium
The University of Western Australia
National Health and Medical Research Council, Australia

Unknown

Postprandial Lipid Metabolism in Familial Hypercholesterolaemia:Effects of Fish Oils (FIFH)

Familial Hypercholesterolaemia | Hypertriglyceridaemia

Australia
Merck Sharp & Dohme LLC

Recruiting

MK-0616 (Oral PCSK9 Inhibitor) Cardiovascular Outcomes Study (MK-0616-015) CORALreef Outcomes

Arteriosclerosis | Hypercholesterolaemia

United States, Taiwan, Canada, Israel, New Zealand, Hong Kong, Argentina, Korea, Republic of, Turkey, Australia, Chile, Brazil, Japan, Colombia, China, United Kingdom, Mexico, Peru
Organon and Co
Merck Sharp & Dohme LLC

Completed

Ezetimibe Plus Simvastatin Versus Simvastatin in Untreated Subjects With High Cholesterol (P03435)

Atherosclerosis | Hypercholesterolaemia
Karo Bio AB

Terminated

Efficacy and Safety Study of Eprotirome in HeFH Patients Who Are on Optimal Standard of Care (AKKA)

Heterozygous Familial Hypercholesterolaemia
Instituto Aragones de Ciencias de la Salud
Hospital Clinic of Barcelona; Instituto de Salud Carlos III

Completed

Effect of Weight Loss on Cholesterol Metabolism in Hereditary Hypercholesterolemias and Overweight or Obesity.

Obesity | Weight Loss | Familial Hypercholesterolemias | Familial Combined Hypercholesterolemia
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Cardiovascular Evaluation of Patients With High Cholesterol and Normal Volunteers

Homozygous Familial Hypercholesterolemic

United States
Sanofi

Completed

Non-interventional Study on the Monthly Administration of 300 mg AliRocumab (PRALUENT®) With the 2 ml SYDNEY Auto-injector (MARS)

Atherosclerotic Cardiovascular Disease | Primary Hypercholesterolaemia and Mixed Dyslipidaemia

Germany
Elpen Pharmaceutical Co. Inc.

Recruiting

Ezetimibe-Rosuvastatin Evaluation Study (ZEUS)

Hypercholesterolemia | Hyperlipidemias | Combinations of Drugs; Dependence

Greece
University of British Columbia
Vancouver Coastal Health Research Institute; Genome British Columbia

Recruiting

Advancing Cardiac Care Unit-based Rapid Assessment and Treatment of hypErcholesterolemia (ACCURATE)

Acute Coronary Syndrome | Familial Hypercholesterolemia | STEMI | NSTEMI - Non-ST Segment Elevation MI | Familial Hypercholesterolemia - Heterozygous | Familial Hypercholesterolemia Due to Genetic Defect of Apolipoprotein B | Familial Hypercholesterolemia Due to Heterozygous LDL Receptor Mutation and other conditions

Canada
Lescuyer Laboratory
BioFortis

Completed

Effect of Limicol on (LDL)-Cholesterol Levels in Moderate Hypercholesterolaemia

Delivery of Health Care

France
National Medical Research Center for Therapy and...
Moscow State University of Medicine and Dentistry

Recruiting

Genetic Testing and Motivational Counseling for FH (GENMOTIV-FH)

Medication Adherence | Adherence, Medication | Treatment Adherence | Familial Hypercholesterolemia | Motivational Interviewing | Adherence, Patient | Treatment Adherence and Compliance | Patient Compliance | Adherence | Hypercholesterolemia, Familial | Patient Adherence | Hypercholesterolemia, Autosomal Dominant and other conditions

Russian Federation
Jose Seijas Amigo

Completed

Study to Evaluate Changes in Cognitive Function in Patients Treated With PCSK9 Inhibitors (MEMOGAL)

Quality of Life | Hypercholesterolemia | Cognitive Function

Spain

Clinical Trials on Undertreatment of Hypercholesterolaemia

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CROs in Denmark

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