Clinical Trials on Undiagnosed Disorders

Total 145651 results

NICHD Neonatal Research Network
National Center for Research Resources (NCRR)

Completed

Vitamin A Supplementation for Extremely-Low-Birth-Weight Infants (Vitamin A)

Sepsis | Respiratory Distress Syndrome, Newborn | Bronchopulmonary Dysplasia | Respiration, Artificial | Infant, Small for Gestational Age | Infant, Premature | Infant, Low Birth Weight | Infant, Newborn

United States
National Institute of Dental and Craniofacial Research...

Completed

Salivary Proteins in Disease and Health

Diabetes Mellitus | Head and Neck Neoplasms | Dental Caries | Sarcoidosis | Cystinosis | Sjorgren's Syndrome

United States
Hoffmann-La Roche
Association Française contre les Myopathies (AFM), Paris

Completed

Safety and Efficacy of Olesoxime (TRO19622) in 3-25 Years SMA Patients.

Spinal Muscular Atrophy Type II | Spinal Muscular Atrophy Type III Non Ambulant

Germany, Italy, France, Belgium, Poland, Netherlands, United Kingdom
Odense University Hospital

Completed

Paroxysmal Atrial Fibrillation in Patients With Acute Ischemic Stroke

Ischemic Stroke | Paroxysmal Atrial Fibrillation | Premature Atrial Complexes

Denmark
VA Office of Research and Development

Completed

Outlook Quality of Life Intervention Study

Cancer | Chronic Obstructive Pulmonary Disease (COPD) | End Stage Renal Disease (ESRD) | Congestive Heart Failure (CHF)

United States
Washington University School of Medicine

Completed

Effect of Diet-induced Weight Loss on HIV-associated Metabolic Syndrome

HIV Infections | Metabolic Syndrome | HIV (Human Immunodeficiency Virus)

United States
Cooperative International Neuromuscular Research...
Carolinas Medical Center lead study site

Completed

Evaluation of Limb-Girdle Muscular Dystrophy

Becker Muscular Dystrophy | Limb-Girdle Muscular Dystrophy, Type 2A (Calpain-3 Deficiency) | Limb-Girdle Muscular Dystrophy, Type 2B (Miyoshi Myopathy, Dysferlin Deficiency) | Limb-Girdle Muscular Dystrophy, Type 2I (FKRP-deficiency)

United States
HealthCore-NERI
National Heart, Lung, and Blood Institute (NHLBI); Thalassemia Clinical Research...

Completed

Thalassemia (Cooley's Anemia) Clinical Research Network (TCRN)

Hematologic Diseases | Iron Overload | Hypertension, Pulmonary | Osteoporosis | Thalassemia | Beta-Thalassemia | Anemia, Cooley's

United States, Canada
Genzyme, a Sanofi Company

Approved for marketing

Alglucosidase Alfa Temporary Access Program (ATAP)

Glycogen Storage Disease Type II (GSD-II) | Acid Maltase Deficiency Disease | Glycogenosis 2 | Pompe Disease (Late-Onset)

United States
Xiangya Hospital of Central South University

Completed

Early NCPAP Before Surfactant Treatment in Very Preterm Infants With RDS

Bronchopulmonary Dysplasia | Nasal Continuous Positive Airway Pressure, | Preterm Infants, | Surfactant Treatment, | Respiratory Distress Syndrome,
Mount Vernon Cancer Centre at Mount Vernon Hospital

Unknown

CA 125 Levels in Treating Patients With Relapsed Advanced Ovarian Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cancer Who Are Receiving Tamoxifen

Ovarian Cancer | Fallopian Tube Cancer | Primary Peritoneal Cavity Cancer

United Kingdom
Cambridge University Hospitals NHS Foundation Trust

Completed

Capecitabine and Streptozocin With or Without Cisplatin in Treating Patients With Unresectable or Metastatic Neuroendocrine Tumors

Islet Cell Tumor | Gastrointestinal Carcinoid Tumor

United Kingdom
National Cancer Institute (NCI)

Completed

Gefitinib in Treating Patients With Cervical Cancer

Cervical Cancer | Ovarian Cancer | Fallopian Tube Cancer | Primary Peritoneal Cavity Cancer

United States
Novartis

Completed

Zoledronate in Treating Patients With Solid Tumors That Have Spread to the Bone

Pain | Lung Cancer | Unspecified Adult Solid Tumor, Protocol Specific | Metastatic Cancer | Hypercalcemia of Malignancy

United States
National Cancer Institute (NCI)

Completed

Tariquidar and Docetaxel to Treat Patients With Lung, Ovarian, Renal and Cervical Cancer

Lung Neoplasms | Ovarian Neoplasms | Cervix Neoplasms | Renal Neoplasms

United States
The University of Texas Health Science Center at...
Sanchez Cancer Center

Terminated

Enbrel Versus Placebo With Radiation Therapy to Combat Fatigue and Cachexia

Neoplasm Metastasis | Lung Cancer | Bone Cancer | Prostate Cancer

United States
Johann Wolfgang Goethe University Hospital

Unknown

Status of Growth Hormone/ Insulin-like Growth Factor-1 (GH/IGF-1) Axis and Growth Failure in Ataxia Telangiectasia (AT) (GHAT)

Growth Failure | Ataxia Telangiectasia

Germany
Mayo Clinic

Completed

Spontaneous Coronary Artery Dissection (SCAD) and Autoimmunity

Multiple Sclerosis | Rheumatoid Arthritis | Systemic Lupus Erythematosus | Uveitis | Vasculitis | Psoriasis | Graves Disease | Systemic Sclerosis | Celiac Disease | Crohn Disease | Type 1 Diabetes Mellitus | Myasthenia Gravis | Ulcerative Colitis | Dermatomyositis | Polymyositis | Vitiligo | Hepatitis, Autoimmune | Polymyalgia... and other conditions

United States
National Cancer Institute (NCI)

Completed

XK469R in Treating Patients With Refractory Hematologic Cancer

Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Adult Acute Megakaryoblastic Leukemia (M7) | Adult Acute Minimally Differentiated Myeloid Leukemia (M0) | Adult Acute Monoblastic Leukemia (M5a) | Adult Acute Monocytic Leukemia (M5b) | Adult Acute Myeloblastic Leukemia... and other conditions

United States
Azienda Unità Sanitaria Locale Reggio Emilia
IRCCS San Raffaele; IRCCS Azienda Ospedaliero-Universitaria di Bologna; University... and other collaborators

Recruiting

National Project on Vaccines, COVID-19 and Frail Patients (VAX4FRAIL)

COVID-19 | Hematologic Diseases | Rheumatic Diseases | Solid Tumor | Neurologic Disorder

Italy
Vascutek Ltd.
Federation of Medical Specialties

Active, not recruiting

French Assessment of the Relay Plus and Relay NBS Plus Thoracic Stent-Graft

Aneurysm Thoracic | Dissection of Thoracic Aorta | Pathology of the Thoracic Aorta | Pseudo-aneurysm, Thoracic | Intramural Haematoma of Thoracic Aorta | Penetrating Ulcer of Aorta (Disorder) | Rupture of the Isthmus

France
Children's Oncology Group
National Cancer Institute (NCI)

Recruiting

Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors

Melanoma | Neuroblastoma | Pancreatic Ductal Adenocarcinoma | Refractory Malignant Solid Neoplasm | Endometrial Carcinoma | Recurrent Ewing Sarcoma | Recurrent Hepatoblastoma | Recurrent Malignant Solid Neoplasm | Recurrent Non-Hodgkin Lymphoma | Recurrent Osteosarcoma | Refractory Ewing Sarcoma | Refractory... and other conditions

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Recruiting

Naive T Cell Depletion for Preventing Chronic Graft-versus-Host Disease in Children and Young Adults With Blood Cancers Undergoing Donor Stem Cell Transplant

Acute Lymphoblastic Leukemia | Acute Leukemia | Blastic Plasmacytoid Dendritic Cell Neoplasm | Acute Leukemia of Ambiguous Lineage | Acute Undifferentiated Leukemia | Acute Biphenotypic Leukemia | Myelodysplastic Syndrome With Excess Blasts-1 | Mixed Phenotype Acute Leukemia | Blasts Under 5 Percent... and other conditions

United States
Shattuck Labs, Inc.

Completed

SL-279252 (PD1-Fc-OX40L) in Subjects With Advanced Solid Tumors or Lymphomas

Melanoma | Renal Cell Carcinoma | Hodgkin Lymphoma | Gastric Adenocarcinoma | Non Small Cell Lung Cancer | Squamous Cell Carcinoma of the Head and Neck | Diffuse Large B Cell Lymphoma | Urothelial Carcinoma | Gastroesophageal Junction Adenocarcinoma | Squamous Cell Carcinoma of the Skin | Squamous Cell Carcinoma... and other conditions

United States, Canada, Belgium, Spain
National Cancer Institute (NCI)

Withdrawn

Testing a New Anti-cancer Drug Combination, Entinostat and GSK525762C, for Advanced and Refractory Solid Tumors and Lymphomas

Advanced Lymphoma | Advanced Malignant Solid Neoplasm | Refractory B-Cell Non-Hodgkin Lymphoma | Refractory Lymphoma | Refractory Malignant Solid Neoplasm | Refractory Pancreatic Carcinoma | Refractory T-Cell Non-Hodgkin Lymphoma | Stage II Pancreatic Cancer AJCC v8 | Stage III Pancreatic Cancer AJCC... and other conditions
University of Nebraska
Nevro Corp

Not yet recruiting

SCS for Patient With Painful Diabetic Neuropathy and Peripheral Arterial Disease

Diabetes Mellitus, Type 2 | Chronic Pain | Peripheral Arterial Disease | Chronic Pain Syndrome | Painful Diabetic Neuropathy | Limb Pain | Spinal Cord Stimulation

United States
Zhongda Hospital

Recruiting

Identification of Risk Factors and Construction of Prediction Model for Postoperative Intestinal Anastomotic Leakage in Ovarian Cancer

Ovarian Cancer

China
Uppsala University Hospital
Norrlands Universitetssjukhus, Umea, Sweden

Recruiting

Early Detection of Relapse in Ovarian Cancer Using Capillary Home-sampling and a Protein Biomarker Test (FOLL-OV)

Ovarian Cancer | Fallopian Tube Cancer | Peritoneal Cancer

Sweden
Assiut University

Not yet recruiting

Vitamin B12 Status and Its Impact on Chronic Haemodialysis Patient (Haemodialysis)

Vitamin B 12 Deficiency | End Stage Renal Disease on Dialysis
University Medical Center Groningen
GlaxoSmithKline

Recruiting

eGPA and Local Inflammation Within the Ear, Nose and Throat Area

EGPA - Eosinophilic Granulomatosis With Polyangiitis

Netherlands
Anemia Working Group Romania
Carol Davila University of Medicine and Pharmacy; Sf Ioan Emergency Clinical... and other collaborators

Recruiting

Effect of Low Protein Diet on Top of Dapagliflozin on Chronic Kidney Disease in Patients With Type 2 Diabetes Mellitus (PRODAPA-CKD)

Chronic Kidney Diseases | Type 2 Diabetes Mellitus

Romania
Brigham and Women's Hospital

Recruiting

Subclinical Primary Aldosteronism in Diabetes At-Risk for Kidney Disease (SubPA-DKD)

Chronic Kidney Diseases | Type 2 Diabetes

United States
Power Life Sciences Inc.

Not yet recruiting

Investigating Participation Patterns Among Recurrent Ovarian Cancer Patients

Recurrent Ovarian Cancer

United States
Centre Hospitalier de Valence

Not yet recruiting

Evaluation of the Medical Service by Socio-aesthetics in Oncology (RCT-SE)

Anxiety Depression | Cancer, Breast | Cancer Pain | Cancer of Colon | Cancer, Lung | Cancer Prostate
Casa Colina Hospital and Centers for Healthcare
University of Southern California; Department of Health and Human Services; Rancho... and other collaborators

Recruiting

Peer Support for Patients With Diabetic Foot Ulcers

Diabetes Mellitus, Type 2 | Diabetic Foot | Diabetes Complications | Diabetic Foot Ulcer | Peripheral Neuropathy | Diabetic Wound

United States
Medical University of Vienna

Recruiting

Vagus Stimulation in Female Long COVID Patients. (Vagus)

Vagus Nerve Diseases | Post-COVID-19 Syndrome | Long COVID | Long Covid19 | Post COVID-19 Condition | Post-COVID Syndrome | Post COVID Condition

Austria
Closed Joint-Stock Company NeoCor
Research Institute for Complex Problems of Cardiovascular Diseases, Russia; CT Medical Limited Liability Company

Recruiting

Study on Efficacy, Safety and Durability of the UniLine Prosthesis in the Treatment of Aortic and Mitral Valve Disease

Diseases of Mitral and Aortic Valves | Valvular Heart Disease (Aortic and Mitral Valves) | Rheumatic Disorders of Mitral and Aortic Valves | Other Congenital Malformations of Aortic and Mitral Valves | Mitral Valve Insufficiency and Aortic Valve Insufficiency

Russian Federation
Centre Hospitalier Metropole Savoie

Recruiting

Prospective Study of Detection of Sarcopenia in Clinical Practice for Patient With Ovarian or Endometrial Cancer (SARCO-GYN)

Ovarian Neoplasms | Sarcopenia

France
Shanghai Yunying Medical Technology
Shanghai 10th People's Hospital

Recruiting

A Clinical Study on Oncolytic Virus Injection (R130) for the Treatment of Relapsed/Refractory Ovarian Cancer

Ovarian Cancer | Fallopian Tube Cancer | Peritoneal Carcinomatosis

China
Fondazione Policlinico Universitario Agostino Gemelli...

Recruiting

Diet in Twin Pregnancy: the Wellness of Mother and Babies. (FIT)

Diet, Healthy | Gestational Diabetes | Intrahepatic Cholestasis of Pregnancy | Food Habits | Twin Pregnancy, Antepartum Condition or Complication | Gestational Hypertension

Italy
Mount Sinai Hospital, Canada
London Health Sciences Centre; Royal Alexandra Hospital; Foothills Medical Centre

Recruiting

Prediction of Intraventricular Hemorrhage Using Echocardiography and Near Infrared Spectroscopy (PIONIRS)

Intraventricular Hemorrhage of Newborn Grade 2 | Intraventricular Hemorrhage of Newborn Grade 3 | Intraventricular Haemorrhage Grade IV

Canada
Intellia Therapeutics

Recruiting

Long-Term Follow-Up (LTFU) of Subjects Dosed With NTLA-2001

Transthyretin-Related (ATTR) Familial Amyloid Cardiomyopathy | Transthyretin-Related (ATTR) Familial Amyloid Polyneuropathy | Wild-Type Transthyretin Cardiac Amyloidosis

United Kingdom, New Zealand, Sweden
Sahlgrenska University Hospital, Sweden
Vastra Gotaland Region

Recruiting

Optimized Care of People With Diabetes and Foot Complication in Primary Care

Diabetes Mellitus, Type 2 | Diabetes Mellitus | Diabetes | Diabetic Foot | Diabetes Complications | Diabetes Mellitus, Type 1

Sweden
Maxima Medical Center

Recruiting

A Pilot Study to Explore the Use of Skin Biopsy as Diagnostic Tool in Anterior Cutaneous Nerve Entrapment Syndrome (ACNES) (Biopsy-ACNES)

Chronic Pain Syndrome | Diagnosis | Nerve Entrapment Syndrome | Anterior Cutaneous Nerve Entrapment Syndrome

Netherlands
Policlinico Hospital
Pfizer

Recruiting

Nosocomial Infections in Patients With ARDS Treated With ECMO (INF-ECMO)

Acute Respiratory Distress Syndrome | Extracorporeal Membrane Oxygenation Complication | Nosocomial Infection

Italy
Third Affiliated Hospital, Sun Yat-Sen University

Recruiting

Efficacy and Safety of Avatrombopag for Treating TCP in HBV-ACLF Patients Receiving ALSS Treatment

Acute-On-Chronic Liver Failure | Hepatitis B, Chronic | Thrombocytopenia

China
Medical College of Wisconsin
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Recruiting

Basic Needs Navigation Intervention to Address Multidimensional Adversity in African Americans With Diabetic Kidney Disease

Diabetes Mellitus, Type 2 | Chronic Kidney Diseases | Diabetic Nephropathies | Healthy Lifestyle

United States
Prokidney
Iqvia Pty Ltd

Not yet recruiting

A Study of Renal Autologous Cell Therapy (REACT) in Participants With Type 2 Diabetes and Chronic Kidney Disease

Chronic Kidney Diseases | Type 2 Diabetes Mellitus
German Diabetes Center

Recruiting

Metabolic Phenotyping and Follow-Up of Patients With and Without Diabetes After New Onset of STEMI (DISTEMI)

Diabetes Mellitus | Insulin Resistance | Non-Alcoholic Fatty Liver Disease | ST-segment Elevation Myocardial Infarction (STEMI)

Germany
University of Missouri-Columbia

Recruiting

Screening for Sacral Agenesis in Offspring of Mothers With Diabetes in Pregnancy

Infant of Diabetic Mother | Sacral Agenesis

United States

Clinical Trials on Undiagnosed Disorders

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Trinidad & Tobago

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations