Clinical Trials on Undiagnosed Disorders

Total 145559 results

National Cancer Institute (NCI)

Completed

RO4929097 and Capecitabine in Treating Patients With Refractory Solid Tumors

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Diffuse Small Cleaved Cell Lymphoma and other conditions

United States, Canada
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Withdrawn

Genetically Modified Peripheral Blood Stem Cell Transplant in Treating Patients With HIV-Associated Non-Hodgkin or Hodgkin Lymphoma

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Diffuse Small Cleaved Cell Lymphoma and other conditions

United States
National Cancer Institute (NCI)

Terminated

Fenretinide and Rituximab in Treating Patients With B-Cell Non-Hodgkin Lymphoma

Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Lymphoblastic Lymphoma | Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma | Recurrent Mantle Cell Lymphoma | Recurrent Marginal Zone... and other conditions

United States
National Cancer Institute (NCI)

Completed

17-DMAG in Treating Patients With Metastatic or Unresectable Solid Tumors or Lymphomas

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Diffuse Small Cleaved Cell Lymphoma and other conditions

United States
National Cancer Institute (NCI)

Completed

MS-275 and Isotretinoin in Treating Patients With Metastatic or Advanced Solid Tumors or Lymphomas

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Diffuse Small Cleaved Cell Lymphoma and other conditions

United States
National Cancer Institute (NCI)

Completed

7-Hydroxystaurosporine and Perifosine in Treating Patients With Relapsed or Refractory Acute Leukemia, Chronic Myelogenous Leukemia or High Risk Myelodysplastic Syndromes

Recurrent Adult Acute Myeloid Leukemia | Adult Acute Megakaryoblastic Leukemia (M7) | Adult Acute Minimally Differentiated Myeloid Leukemia (M0) | Adult Acute Monoblastic Leukemia (M5a) | Adult Acute Monocytic Leukemia (M5b) | Adult Acute Myeloblastic Leukemia With Maturation (M2) | Adult Acute... and other conditions

United States
Regeneron Pharmaceuticals

Not yet recruiting

A Study to Learn if 27T51, a Mucin-16 (MUC16) Protein Targeting Immune Cell Therapy, Administered Alone or in Combination is Safe and How Well it Works for Adult Participants With Recurrent or Treatment Resistant Ovarian Cancers

Fallopian Tube Cancer | Epithelial Ovarian Cancer | Primary Peritoneal Carcinoma

United States
Swiss GO Trial Group
Tumor Profiler Center Switzerland

Not yet recruiting

OV Precision: Study Examining the Benefit of a Tumor- and Patient-specific Cancer Therapy (OVPrecision)

Fallopian Tube Neoplasms | Ovarian Neoplasm Epithelial | High-grade Serous Ovarian Carcinoma (HGSOC) | Ovarian Endometrioid Carcinoma

Switzerland
PYC Therapeutics

Not yet recruiting

SAD of IVT PYC-001 in OPA1 Mutation-Associated Autosomal Dominant Optic Atrophy (Sundew)

Autosomal Dominant Optic Atrophy | Kjer Optic Atrophy | OPA1 Gene Mutation | Hereditary Optic Atrophies
Maastricht University Medical Center
Diabetes Fonds

Recruiting

The Effect of Pyridoxamine Supplementation on Microvascular Function in Type 2 Diabetes (PYRAMID)

Type 2 Diabetes | Neuropathy, Diabetic | Nephropathy, Diabetic | Microvascular Function | Retinopathy, Diabetic

Netherlands
Hans Bahlmann
Linkoeping University

Recruiting

Spinal Morphine or Intravenous Lidocaine in Robot-assisted Upper Urologic Surgery (SMILe)

Renal Cancer | Ureter Cancer | Other Specified Disorders of Kidney and Ureter | Benign Neoplasm of Ureter | Calculus of Kidney and Ureter | Ureteric Reflux | Congenital Ureteric Anomaly | Benign Renal Neoplasm

Sweden
AstraZeneca

Recruiting

Assessment of Safety of Olaparib in Chinese Patients With Ovarian Cancer in the Real-World Setting

Using NCID Database to Assess the Safety of Olaparib in Chinese Patients With Ovarian Cancer by Examining the Incidence, Seriousness, and Severity of All AE

China
Dana-Farber Cancer Institute
ImmunityBio, Inc.

Not yet recruiting

Intraperitoneal Cytokine-Induced Memory Like (CIML) Natural Killer (NK) Cells in Recurrent Ovarian Cancer

Ovarian Cancer | Platinum-resistant Ovarian Cancer | Ovarian Carcinoma | Recurrent Ovary Cancer | Ovarian Carcinoma, Recurrent

United States
The First Hospital of Jilin University

Not yet recruiting

To Explore the Feasibility of Dynamic Changes of TCR Diversity in Peripheral Blood in Monitoring Recurrence and Evaluating Prognosis of Epithelial Ovarian Cancer

Epithelial Ovarian Cancer | Stage IV Ovarian Cancer | Stage III Ovarian Cancer
Foundation For Rare Disease Research
Institute for Asthma & Allergy; Virant Diagnostics, Inc.; MedBio Reference Laboratories...

Not yet recruiting

Angioedema Biomarker Research Study

Angioedema | Urticaria | C1 Inhibitor Deficiency | Angioedemas, Hereditary | Mastocytosis | Indolent Systemic Mastocytosis | Systemic Mastocytoses | ACE Inhibitor-Induced Angioedema
Brigham and Women's Hospital
Agency for Healthcare Research and Quality (AHRQ)

Not yet recruiting

Care Transitions App for Patients With Multiple Chronic Conditions

Heart Failure | Diabetes Mellitus | Diabetes | Chronic Kidney Diseases | Congestive Heart Failure
University Hospital Ostrava
University of Ostrava

Recruiting

Nasal Obstruction Compared by Rhinomanometry and Nasal Inspiratory Peak Flow After Endoscopic Nasal Surgery

Nasal Obstruction | Pituitary Adenoma Invasive

Czechia
Universitat Jaume I

Recruiting

Abdominopelvic Cancer Prehabilitation

Cancer of Colon | Prehabilitation | Cancer of Rectum | Cancer, Ovarian

Spain
University of Aarhus
Department of Clinical Medicine, Aarhus University; Department of Gynaecology... and other collaborators

Recruiting

Improved Diagnosis of Ovarian Cancer

Ovarian Cysts | Ovarian Neoplasms | Ovarian Cancer | Adnexal Mass | Adnexal Lesion | Adnexal Carcinoma | Adnexal Neoplasm

Denmark
McMaster University
Canadian Institutes of Health Research (CIHR)

Recruiting

Relative Impacts on Preventative Primary Care--a Longitudinal Evaluation of COVID-19:Phase 1 (RIPPLE-C)

Diabetes Mellitus | Chronic Kidney Diseases | Chronic Obstructive Pulmonary Disease | Osteoarthritis | Dementia | Congestive Heart Failure | Depression, Anxiety

Canada
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Impact of ECMO Cannula Chlorhexidine-impregnated Dressings to Decrease Extracorporeal Membrane Oxygenation-cannula Related Infection Rate (DRESSING-ECMO)

Infections | Acute Respiratory Distress Syndrome | Cardiogenic Shock | Extracorporeal Membrane Oxygenation Complication
Hopital du Sacre-Coeur de Montreal

Not yet recruiting

Optic Nerve Sheath Ultrasound in Giant Cell Arteritis (ONS-GCA)

Optic Neuropathy, Ischemic | Anterior Ischemic Optic Neuropathy | Giant Cell Arteritis

Canada
Centre Hospitalier Universitaire Dijon
Novartis Pharmaceuticals

Recruiting

Assessment of the Efficacy and Safety of Alpelisib (BYL719) in Pediatric and Adult Patients With Megalencephaly-CApillary Malformation Polymicrogyria Syndrome (MCAP) (SESAM)

Megalencephaly-capillary Malformation Polymicrogyria Syndrome (MCAP)

France
Acrivon Therapeutics
GOG Foundation

Recruiting

A Study of ACR-368 in Ovarian Carcinoma, Endometrial Adenocarcinoma, and Urothelial Carcinoma

Platinum-resistant Ovarian Cancer | Urothelial Carcinoma | Endometrial Adenocarcinoma

United States
OPKO Health, Inc.

Recruiting

Phase 3 Safety and Efficacy Study of CTAP101 Extended-release Capsules in Children With Secondary Hyperparathyroidism

Secondary Hyperparathyroidism | Chronic Kidney Disease stage4 | Chronic Kidney Disease stage3 | Vitamin d Deficiency

United States
Uniformed Services University of the Health Sciences

Recruiting

Ivabradine for Long-Term Effects of COVID-19 With POTS Cohort (COVIVA)

Postural Orthostatic Tachycardia Syndrome | Long Haul COVID

United States
Vitti Labs, LLC

Recruiting

Safety and Effectiveness of Placental Derived Exosomes and Umbilical Cord Mesenchymal Stem Cells in Moderate to Severe Acute Respiratory Distress Syndrome (ARDS) Associated With the Novel Corona Virus Infection (COVID-19)

Respiratory Distress Syndrome | COVID-19 Acute Respiratory Distress Syndrome

United States
Roswell Park Cancer Institute
National Comprehensive Cancer Network

Recruiting

Quality of Life Intervention to Inform Patient Decision-Making in Early-Stage Lung Cancer

Lung Non-Small Cell Carcinoma | Stage II Lung Cancer AJCC v8 | Stage IIA Lung Cancer AJCC v8 | Stage IIB Lung Cancer AJCC v8 | Stage I Lung Cancer AJCC v8 | Stage IA1 Lung Cancer AJCC v8 | Stage IA2 Lung Cancer AJCC v8 | Stage IA3 Lung Cancer AJCC v8 | Stage IB Lung Cancer AJCC v8

United States
Ramos Mejía Hospital

Recruiting

Recruitment Assessment in Patients With Acute Respiratory Distress Syndrome and Covid-19

Acute Respiratory Distress Syndrome | Recruitment | COVID-19 Pneumonia

Argentina
Pharmazz, Inc.

Not yet recruiting

Multicentric, Randomized Study to Assess Safety and Efficacy of Centhaquine in COVID-19 Patients With ARDS

COVID-19 Acute Respiratory Distress Syndrome
Assistance Publique - Hôpitaux de Paris

Recruiting

Impact of COVID-19 SARS-CoV-2 Variability in ICU Hospitalized Patients With Severe Disease (SEVARVIR)

SARS-CoV2 Infection | Mutation | COVID-19 Acute Respiratory Distress Syndrome

France
University Medical Center Groningen
UMCG Kanker Researchfonds

Recruiting

Early Ageing During Therapy in AYA Cancer Patients

Cervical Cancer | Leukemia | Cancer | Breast Cancer | Hodgkin Lymphoma | Osteosarcoma | Ewing Sarcoma | Testicular Cancer

Netherlands
NUMEN Foundation
Hospital de Emergencias Enfermera Isabel Zendal de Madrid

Not yet recruiting

Effect of Vojta Therapy on Covid-19 Respiratory Disease

COVID-19 Acute Respiratory Distress Syndrome
Daping Hospital and the Research Institute of Surgery...
Children's Hospital of Chongqing Medical University

Recruiting

Optimal Dose of Surfactant for Preterm Infants With Respiratory Distress Syndrome

Respiratory Distress Syndrome, Newborn | Bronchopulmonary Dysplasia | Patent Ductus Arteriosus | Preterm

China
National Cancer Institute (NCI)

Recruiting

Testing the Combination of ZEN003694 and Nivolumab With or Without Ipilimumab in Solid Tumors

Recurrent Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm | Recurrent Platinum-Resistant Ovarian Carcinoma | Refractory Ovarian Carcinoma

United States
ARCAGY/ GINECO GROUP
Merck Sharp & Dohme LLC; OSE Immunotherapeutics

Recruiting

OSE2101 Alone or in Combination With Pembrolizumab vs BSC in Patient With Platinum-sensitive Recurrent OC (TEDOVA)

Relapsed Ovarian Cancer | Platinum-sensitive Ovarian Cancer

Belgium, France, Germany
Martin-Luther-Universität Halle-Wittenberg

Not yet recruiting

Treatment of Classic Mid-trimester PPROM by Means of Continuous Amnioinfusion (AmnionFlush)

Necrotizing Enterocolitis | Intracranial Hemorrhages | Bronchopulmonary Dysplasia

Germany
M.D. Anderson Cancer Center

Recruiting

Prediction of Recurrence Among Low Risk Endometrial Cancer Patients

FIGO Grade 1 Endometrial Endometrioid Adenocarcinoma | FIGO Grade 2 Endometrial Endometrioid Adenocarcinoma

United States
SWOG Cancer Research Network
National Cancer Institute (NCI)

Recruiting

A Study of miRNA 371 in Patients With Germ Cell Tumors

Seminoma | Germ Cell Tumor | Metachronous Malignant Neoplasm | Stage I Testicular Cancer AJCC v8 | Stage IA Testicular Cancer AJCC v8 | Stage IB Testicular Cancer AJCC v8 | Stage IS Testicular Cancer AJCC v8

Canada, United States, Guam
Beijing Anzhen Hospital

Recruiting

China Extracorporeal Life Support Registry

Heart Failure | Cardiac Arrest | Acute Respiratory Distress Syndrome | Cardiogenic Shock | Acute Respiratory Failure

China
Center for Neurological Studies
Novo Nordisk A/S

Recruiting

Growth Hormone Replacement Therapy for Retried Professional Football Players

TBI (Traumatic Brain Injury) | Growth Hormone Deficiency | Hypopituitarism | Sport Injury | Concussion, Brain | Anterior Pituitary Hyposecretion Syndrome

United States
National Cancer Institute (NCI)

Recruiting

A Study of the Drugs Selumetinib Versus Carboplatin/Vincristine in Patients With Neurofibromatosis and Low-Grade Glioma

Neurofibromatosis Type 1 | Low Grade Glioma | Visual Pathway Glioma

United States, Canada, Puerto Rico
William Shomali
Incyte Corporation

Recruiting

Ruxolitinib in Treating Patients With Hypereosinophilic Syndrome or Primary Eosinophilic Disorders

Eosinophilia | Hypereosinophilic Syndrome | Blasts More Than 5 Percent of Bone Marrow Nucleated Cells | Splenomegaly | Hepatomegaly | Chronic Eosinophilic Leukemia, Not Otherwise Specified | JAK2 Gene Mutation | BCR-JAK2 Fusion Protein Expression | Blasts 20 Percent or Less of Peripheral Blood White... and other conditions

United States
Target PharmaSolutions, Inc.

Recruiting

A Longitudinal Observational Study of Patients Undergoing Therapy for IMISC (TARGET-DERM)

Psoriasis | Atopic Dermatitis | Vitiligo | Hidradenitis Suppurativa | Alopecia Areata | Chronic Spontaneous Urticaria

United States, Spain, Canada, Germany
Leiden University Medical Center
Amgen

Recruiting

Denosumab in Subjects With Giant Cell Rich Tumors of Bone

Aneurysmal Bone Cysts | Giant Cell Granuloma | Osteoblastoma | Chondroblastoma | Chondromyxoid Fibroma

France, Italy, Netherlands
AstraZeneca

Recruiting

iCaReMe Global Registry (iCaReMe)

Heart Failure | Hypertension | Type 2 Diabetes | Chronic Kidney Disease

Greece, Peru, Mexico, Costa Rica, Ecuador, Egypt, Ghana, India, Indonesia, Kenya, Nigeria, Philippines, South Africa
University of Alabama at Birmingham

Recruiting

Pulmonary Function Using Non-invasive Forced Oscillometry (PUFFOR)

Infant, Newborn, Diseases | Infant, Premature, Diseases | Respiratory Distress Syndrome, Newborn | Bronchopulmonary Dysplasia | Meconium Aspiration Syndrome | Transient Tachypnea of the Newborn

United States
Baylor College of Medicine
National Institute of Neurological Disorders and Stroke (NINDS)

Recruiting

Prediction of Brain Injury in Premature Infants

Brain Injury | Intraventricular Hemorrhage | Periventricular Leukomalacia | Extreme Prematurity

United States
ATI Holdings, LLC

Recruiting

ATI Evidence-based Guide Investigating Clinical Services (AEGIS)

Osteoarthritis | Knee Osteoarthritis | Carpal Tunnel Syndrome | Shoulder Impingement Syndrome | Sprain | Hip Osteoarthritis | Fracture | Spine Osteoarthritis

United States
Medical University of Vienna

Recruiting

Establishment of a Tumor Bank for Tissue Samples

Endocrine Gland Neoplasms | Breast Neoplasms | Lung Neoplasms | Colorectal Neoplasms | Ovarian Neoplasms | Neoplasms of the Female Genitalia

Austria, Germany, Belgium

Clinical Trials on Undiagnosed Disorders

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Kenya

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations