Clinical Trials on Unknown Primary Cancer

Total 97548 results

Centre Leon Berard
GlaxoSmithKline

Recruiting

PREventing Second Cancers With DOSTARlimab (PREDOSTAR)

Recurrent Cancer | Second Cancer | Primary Cancer

France
The University of Texas Health Science Center,...
Napo Pharmaceuticals, Inc.

Recruiting

Yield of Diagnostic Tests and Effects of Crofelemer for Chronic Idiopathic Diarrhea In Non-HIV Patients

Chronic Diarrhea of Unknown Origin

United States
Samuel Vilchez
National Autonomous University of Nicaragua; Ministerio de Salud de Nicaragua; GID BIO

Completed

CKDu Treated With Intra-arterial Infusion of Autologous SVF Cells

Chronic Renal Failure of Unknown Cause

Nicaragua
University Hospital, Rouen

Completed

Targeted Next-generation Sequencing Panel for Identification of Germline Mutations in Early Onset Cancers With Sporadic or Hereditary Presentation (PANEL)

Breast Cancer | Colorectal Cancer | Ovarian Cancer | Pediatric Cancers | Multiple Primary Malignant Tumours

France
Assistance Publique - Hôpitaux de Paris

Completed

Unknown Cause of Acute Liver Failure (HASIPRO)

Liver Failure | Unknown Etiology

France
University of Utah

Withdrawn

A Phase I/II Study of Tivozanib and Erlotinib as Initial Treatment for Metastatic Non-small Cell Lung Cancer Assigned by VeriStrat® Serum Proteomic Evaluation

Non-small Cell Lung Cancer | Stage IV Disease | EGFR Unknown or Wild-type
Medtronic Cardiac Rhythm and Heart Failure

Completed

SEEQ™ Performance Study

Arrhythmia Type Unknown

United States
University of Southampton
BioNTech SE

Completed

HARE-40: HPV Anti-CD40 RNA vaccinE (HARE-40)

Unknown Primary Tumors | Head and Neck Neoplasm | Cervical Neoplasm | Penile Neoplasms Malignant | Human Papilloma Virus Related Carcinoma

United Kingdom
Keymed Biosciences Co.Ltd

Not yet recruiting

A Study of CM310 in Subjects With Chronic Pruritus

Chronic Pruritus of Unknown Origin
Aposense Ltd.

Terminated

18F ML-10 for Early Detection of Response of Brain Metastases to SRS

Metastasis to Brain of Unknown Primary
Emory University
National Cancer Institute (NCI); Pfizer; National Institutes of Health (NIH)

Completed

Palbociclib With Cisplatin or Carboplatin in Advanced Solid Tumors

Sarcoma | Head and Neck Cancer | Stage IIIA Non-Small Cell Lung Cancer | Stage IIIB Non-Small Cell Lung Cancer | Colorectal Cancer | Ovarian Cancer | Bladder Cancer | Stage IV Non-Small Cell Lung Cancer | Stage III Pancreatic Cancer | Stage IV Breast Cancer | Stage IIIA Breast Cancer | Stage IIIB Breast Cancer | Stage IIIC Breast Cancer and other conditions

United States
Taris Biomedical LLC
Bristol-Myers Squibb

Terminated

Safety and Tolerability of TAR-200 and Nivolumab in Subjects With Muscle-Invasive Bladder Cancer

Bladder Cancer TNM Staging Primary Tumor (T) T2 | Bladder Cancer TNM Staging Primary Tumor (T) T2A | Bladder Cancer TNM Staging Primary Tumor (T) T2B | Bladder Cancer TNM Staging Primary Tumor (T) T3 | Bladder Cancer TNM Staging Primary Tumor (T) T3A | Bladder Cancer TNM Staging Primary Tumor... and other conditions

United States
China Medical University Hospital
Academia Sinica, Taiwan

Unknown

Genomic Study of Congenital Malformation

Genomic Aberrations in Patients Diagnosed as Congenital Malformation With Unknown Etiology

Taiwan
University of Rome Tor Vergata
University Of Perugia; University of L'Aquila

Completed

Intravesical Adjuvant Electromotive Mitomycin-C (EMDA/MMC)

Bladder Cancer TNM Staging Primary Tumor (T) Ta | Bladder Cancer TNM Staging Primary Tumor (T) T1 | Bladder Cancer Transitional Cell Grade

Italy
Memorial Sloan Kettering Cancer Center

Completed

Breast MRI Spectroscopy

Suspicion of, or Known Breast Cancer

United States
University of Chicago
National Cancer Institute (NCI)

Completed

Genetic Analysis-Guided Dosing of FOLFIRABRAX in Treating Patients With Advanced Gastrointestinal Cancer

Pancreatic Adenocarcinoma | Gastric Adenocarcinoma | Metastatic Pancreatic Adenocarcinoma | Malignant Gastrointestinal Neoplasm | Stage III Pancreatic Cancer | Stage IV Pancreatic Cancer | Gallbladder Carcinoma | Stage IV Gallbladder Cancer | Stage IV Gastric Cancer | Stage IIIA Gallbladder Cancer | Stage... and other conditions

United States
Assistance Publique Hopitaux De Marseille

Unknown

Digestive Microbiota Transplant

Antibiotic Resistant Infection | Clostridium Difficile | Chronic Diarrhea of Unknown Origin

France
University Health Network, Toronto

Recruiting

Genomic Investigation of Unusual Responders (GENIUS)

Cancer | Breast Cancer | Colorectal Cancer | Non-small Cell Lung Cancer | Melanoma (Skin) | Genitourinary Cancer | Gynecological Cancer | Rare Cancer | Carcinoma of Unknown Primary | Pancreatobiliary Gastrointestinal Cancer | Upper Aerodigestive Tract Cancer

Canada
AstraZeneca

Completed

Evaluation of Target Organs Damage in Hypertensive Patients (PreVENT-A GP)

Hypertensive | Target Organs Damage | no Known Cardiovascular | no Known Renal Disease

France
Fadoi Foundation, Italy

Recruiting

Fever of Unknown Orgin Registry in Internal Medicine Unit and Infectious Disease Units (FUO)

Fever of Unknown Origin

Italy
Foundation Medicine
The Cleveland Clinic; Rush University Medical Center; St. Luke's Hospital and... and other collaborators

Completed

Outcomes of FoundationOne Directed Therapy in Cancer of Unknown Primary

Neoplasms, Unknown Primary | CUP | Metastatic Disease | Poorly Differentiated Adenocarcinoma | Poorly Differentiated Carcinoma | Squamous Carcinoma Poorly Differentiated

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Thermal Ablation and Spine Stereotactic Radiosurgery in Treating Patients With Spine Metastases at Risk for Compressing the Spinal Cord

Sarcoma | Metastatic Melanoma | Thyroid Gland Carcinoma | Metastatic Malignant Neoplasm of Unknown Primary | Spinal Cord Compression | Stage IV Breast Cancer AJCC v6 and v7 | Malignant Digestive System Neoplasm | Metastatic Malignant Neoplasm in the Spine | Metastatic Kidney Carcinoma | Metastatic Head... and other conditions

United States
Zhujiang Hospital

Recruiting

A Multicenter RCT Study of 3DV Technology in the Diagnosis and Treatment of PLC

Primary Liver Cancers

China
Kasey Phifer

Terminated

PEMF Therapy to Treat Lingering Symptoms of Lyme Disease After Treatment With Antibiotics (PEMF)

Lyme Disease | Lyme Arthritis | Lyme Neuroborreliosis | Unknown Origin Fever

United Kingdom
SpeciCare
University of Washington; Georgia Institute of Technology; Predictive Oncology; Netnoid... and other collaborators

Recruiting

The PIONEER Initiative: Precision Insights On N-of-1 Ex Vivo Effectiveness Research Based on Individual Tumor Ownership (Precision Oncology) (PIONEER)

Melanoma | Sarcoma | Renal Cell Carcinoma | Breast Cancer | Hepatocellular Carcinoma | Transitional Cell Carcinoma | Glioblastoma Multiforme | Cholangiocarcinoma | Small-cell Lung Cancer | Oligodendroglioma | Cancer of Head and Neck | Cancer of Liver | Cancer of Pancreas | Cancer of Brain and Nervous System | Adrenal... and other conditions

United States
The Netherlands Cancer Institute

Recruiting

The Prospective Observational COMPRAYA Cohort Study (COMPRAYA)

Cancer | Fertility Issues | Genetic Disease | Lifestyle | Survivorship | Distress, Emotional | Second Cancer

Netherlands
Arbeitsgemeinschaft medikamentoese Tumortherapie
Roche Pharma AG; AstraZeneca

Recruiting

Genomic Testing and Resulting Medical Decisions

Hematologic Neoplasms | Cancer Head Neck | Cancer, Breast | Cancer of Stomach | Cancer of Unknown Origin | Cancer Colorectal | Cancer, Lung | Cancer of Skin | Cancer of Esophagus | Cancer Refractory | Cancer, Bladder | Cancer, Uterus | Cancer Cervix | Cancer Liver | Cancer, Kidney

Austria
Dartmouth-Hitchcock Medical Center
National Cancer Institute (NCI)

Completed

Combination Chemotherapy Plus Filgrastim in Treating Patients With Advanced Solid Tumors

Sarcoma | Breast Cancer | Head and Neck Cancer | Gastric Cancer | Pancreatic Cancer | Esophageal Cancer | Ovarian Cancer | Lung Cancer | Prostate Cancer | Bladder Cancer | Melanoma (Skin) | Carcinoma of Unknown Primary

United States
Beijing Friendship Hospital
Beijing Chao Yang Hospital

Unknown

Clinical Research for the Diagnosis of Tick-borne Diseases in Patients With Unexplained Acute Fever

Fever of Unknown Origin | Tick-borne Diseases

China
Excel Diagnostics and Nuclear Oncology Center

Withdrawn

Phase-II Study of Lu177DOTATOC in Adults With STTR(+)Pulmonary, Pheochromocytoma, Paraganglioma, Unknown Primary, Thymus NETs (PUTNET), or Any Other Non-.GEP-NET. (PUTNET)

Neuroendocrine Tumors | Pheochromocytoma | Paraganglioma | Unknown Primary Tumors | Pulmonary Neuroendocrine Neoplasm | Thymus Carcinoid | Neuroendocrine Skin Carcinoma | Neuroendocrine Breast Tumor | Neuroendocrine Carcinoma Metastatic | Neuroendocrine Neoplasm of Ovary

United States
University of Pennsylvania

Terminated

RCT for Women With a Persisting Pregnancy of Unknown Location (PPUL)

Ectopic Pregnancy | Persistent Pregnancy of Unknown Location

United States
University of Nebraska

Recruiting

Integrated Cancer Repository for Cancer Research (iCaRe2)

Melanoma | Sarcoma | Kidney Cancer | Leukemia | Breast Cancer | Laryngeal Cancer | Hypopharyngeal Cancer | Nasopharyngeal Cancer | Multiple Myeloma | Gastric Cancer | Pancreatic Cancer | Esophageal Cancer | Small Intestine Cancer | Ovarian Cancer | Lynch Syndrome | Lung Cancer | Rectal Cancer | Prostate Cancer | Gastrointestinal... and other conditions

United States
University of Virginia
National Cancer Institute (NCI)

Completed

Vaccine Therapy in Treating Patients With Ovarian Epithelial or Primary Peritoneal Cancer

Ovarian Cancer | Primary Peritoneal Cavity Cancer

United States
Gynecologic Oncology Group
National Cancer Institute (NCI)

Completed

Combination Chemotherapy in Treating Patients With Stage III or Stage IV Ovarian Epithelial or Primary Peritoneal Cancer

Ovarian Cancer | Primary Peritoneal Cavity Cancer

United States, Canada
Gynecologic Oncology Group
National Cancer Institute (NCI)

Terminated

Combination Chemotherapy in Treating Patients With Previously Untreated Stage III or Stage IV Ovarian or Primary Peritoneal Cancer

Ovarian Cancer | Primary Peritoneal Cavity Cancer

United States, Canada
Merck Sharp & Dohme LLC

Terminated

Paclitaxel Plus Carboplatin With or Without SCH-58500 in Treating Patients With Newly Diagnosed Stage III Ovarian or Stage III Primary Peritoneal Cancer

Ovarian Cancer | Primary Peritoneal Cavity Cancer
Grand River Hospital

Unknown

Telemedicine Clinic for Prostate Cancer Patients

Cancer, Treatment-Related

Canada
Saliva Biomarkers, Inc.

Unknown

Comparison of Salivary and Serum Free Testosterone in Normal and Hypogonadal Men

Known Androgen Deficiency

United States
University of Hawaii
GlaxoSmithKline

Recruiting

TSR-022 (Anti-TIM-3 Antibody) and TSR-042 (Anti-PD-1 Antibody) in Patients With Liver Cancer

Advanced Adult Primary Liver Cancer | Localized Unresectable Adult Primary Liver Cancer | Adult Primary Liver Cancer

United States
Roswell Park Cancer Institute
National Cancer Institute (NCI)

Withdrawn

Vaccine Therapy and IDO1 Inhibitor INCB024360 in Treating Patients With Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cancer Who Are in Remission

Stage IV Ovarian Epithelial Cancer | Recurrent Ovarian Epithelial Cancer | Recurrent Primary Peritoneal Cavity Cancer | Stage IV Primary Peritoneal Cavity Cancer | Recurrent Fallopian Tube Cancer | Stage IIA Fallopian Tube Cancer | Stage IIB Fallopian Tube Cancer | Stage IIC Fallopian Tube Cancer | Stage... and other conditions
Yale University
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Optimal Treatment for Women With a Persisting Pregnancy of Unknown Location (ACTorNOT)

Ectopic Pregnancy | Persistent Pregnancy of Unknown Location

United States
Hartford Hospital

Completed

Development of an Anxiety Sensitivity-Based Intervention for Substance Use and Anxiety Comorbidity (SUD/Anx)

Other (or Unknown) Substance Use Disorders

United States
Roswell Park Cancer Institute
National Cancer Institute (NCI); Sanofi Pasteur, a Sanofi Company

Completed

Sirolimus and Vaccine Therapy in Treating Patients With Stage II-IV Ovarian Epithelial, Fallopian Tube, or Primary Peritoneal Cavity Cancer

Stage IV Ovarian Epithelial Cancer | Recurrent Ovarian Epithelial Cancer | Recurrent Primary Peritoneal Cavity Cancer | Stage IV Primary Peritoneal Cavity Cancer | Recurrent Fallopian Tube Cancer | Stage IIA Fallopian Tube Cancer | Stage IIB Fallopian Tube Cancer | Stage IIC Fallopian Tube Cancer | Stage... and other conditions

United States
Abramson Cancer Center of the University of Pennsylvania

Completed

RADVAX: A Stratified Phase I Trial of Pembrolizumab With Hypofractionated Radiotherapy in Patients With Advanced and Metastatic Cancers

Metastatic Cancers

United States
Gynecologic Oncology Group
National Cancer Institute (NCI)

Completed

Gefitinib in Treating Patients With Recurrent or Persistent Ovarian Epithelial Cancer or Primary Peritoneal Cancer

Ovarian Cancer | Primary Peritoneal Cavity Cancer

United States, Canada, United Kingdom, Australia
Gynecologic Oncology Group
National Cancer Institute (NCI)

Completed

Enzastaurin in Treating Patients With Persistent or Recurrent Ovarian Epithelial Cancer or Primary Peritoneal Cancer

Ovarian Cancer | Primary Peritoneal Cavity Cancer

United States
Gynecologic Oncology Group
National Cancer Institute (NCI); Eli Lilly and Company

Completed

Pemetrexed Disodium in Treating Patients With Ovarian Epithelial Cancer or Primary Peritoneal Cancer

Ovarian Cancer | Primary Peritoneal Cavity Cancer

United States
Gynecologic Oncology Group
National Cancer Institute (NCI)

Terminated

Paclitaxel in Treating Patients With Ovarian Epithelial Cancer or Primary Peritoneal Cancer

Ovarian Cancer | Primary Peritoneal Cavity Cancer

United States
University of Wisconsin, Madison

Completed

Stress Reduction in Ovarian Cancer

Ovarian, Fallopian, and Primary Peritoneal Cancer

United States
Memorial Sloan Kettering Cancer Center
Genentech, Inc.

Recruiting

Trial of Ado-Trastuzumab Emtansine for Patients With HER2 Amplified or Mutant Cancers

Lung Cancer | Bladder Cancer | Solid Tumor Cancers | Urinary Tract Cancers

United States

Clinical Trials on Unknown Primary Cancer

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Slovenia

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

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