Clinical Trials on Unresectable Malignant Gastrointestinal Stromal Tumor

Total 3478 results

Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Recruiting

Phase I Clinical Trial of TQB3915 Tablets in Subjects With Advanced Malignant Solid Tumors

Advanced Malignant Tumor

China
Shanghai Hengrui Pharmaceutical Co., Ltd.

Recruiting

A First-in-human Study of HRS2398 Tablets in Subjects With Advanced Malignant Tumors

Advanced Malignant Tumor

China
Qilu Pharmaceutical Co., Ltd.

Recruiting

A Study of Bispecific Antibody QLS31901 in Patients With Advanced or Metastatic Malignancies

Advanced Malignant Tumor

China
Jiangsu Aosaikang Pharmaceutical Co., Ltd.
Jiangsu Aosaikang Biomedicine Co. LTD.

Recruiting

A 1/2 Phase Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Antitumor Activity of ASKB589 in Patients With Locally Advanced or Metastatic Solid Tumors

Malignant Solid Tumor

China
Nanjing Leads Biolabs Co.,Ltd
Henan Cancer Hospital; Hunan Cancer Hospital; Shandong Cancer Hospital and Institute

Completed

Evaluation of LBL-003 Phase I Study in Patients With Advanced Malignancies

Advanced Malignant Tumor

China
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Unknown

A Study of TQ-B3101 Capsules in Subjects With Advanced Malignant Tumor

Advanced Malignant Tumor

China
National Cancer Institute (NCI)

Active, not recruiting

Pazopanib Hydrochloride in Treating Patients With Progressive Carcinoid Tumors

Metastatic Digestive System Neuroendocrine Tumor G1 | Recurrent Digestive System Neuroendocrine Tumor G1 | Regional Digestive System Neuroendocrine Tumor G1 | Metastatic Neuroendocrine Tumor | Midgut Neuroendocrine Tumor G1 | Foregut Neuroendocrine Tumor | Hindgut Neuroendocrine Tumor | Neuroendocrine...

Canada, United States
Children's Oncology Group
National Cancer Institute (NCI)

Recruiting

Biomarkers in Tumor Tissue Samples From Patients With Newly Diagnosed Neuroblastoma or Ganglioneuroblastoma

Localized Resectable Neuroblastoma | Localized Unresectable Neuroblastoma | Regional Neuroblastoma | Stage 4S Neuroblastoma | Ganglioneuroblastoma | Stage 4 Neuroblastoma

United States, Puerto Rico, Canada, Australia, New Zealand, Netherlands, Saudi Arabia, Switzerland
OHSU Knight Cancer Institute
National Institute of Neurological Disorders and Stroke (NINDS); Oregon Health...

Active, not recruiting

Melphalan, Carboplatin, Mannitol, and Sodium Thiosulfate in Treating Patients With Recurrent or Progressive CNS Embryonal or Germ Cell Tumors

Medulloblastoma | Recurrent Malignant Germ Cell Tumor | Recurrent Medulloblastoma | Germ Cell Tumor | Primitive Neuroectodermal Tumor | Medulloepithelioma | Recurrent Primitive Neuroectodermal Tumor | Embryonal Tumor With Multilayered Rosettes, C19MC-Altered | Recurrent Childhood Central Nervous System... and other conditions

United States
National Cancer Institute (NCI)

Completed

Gefitinib in Treating Patients With Progressive Metastatic Neuroendocrine Tumors

Gastrinoma | Glucagonoma | Insulinoma | Metastatic Gastrointestinal Carcinoid Tumor | Pancreatic Polypeptide Tumor | Recurrent Gastrointestinal Carcinoid Tumor | Recurrent Islet Cell Carcinoma | Somatostatinoma | WDHA Syndrome

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Prognostic Biomarkers in Tumor Tissue Samples From Young Patients With Neuroblastoma

Recurrent Neuroblastoma | Disseminated Neuroblastoma | Localized Resectable Neuroblastoma | Localized Unresectable Neuroblastoma | Stage 4S Neuroblastoma

United States
Children's Oncology Group
National Cancer Institute (NCI)

Active, not recruiting

Induction Therapy Including 131 I-MIBG and Chemotherapy in Treating Patients With Newly Diagnosed High-Risk Neuroblastoma Undergoing Stem Cell Transplant, Radiation Therapy, and Maintenance Therapy With Isotretinoin

Localized Resectable Neuroblastoma | Localized Unresectable Neuroblastoma | Regional Neuroblastoma | Stage 4S Neuroblastoma | Ganglioneuroblastoma | Stage 4 Neuroblastoma

United States
Sichuan Baili Pharmaceutical Co., Ltd.
SystImmune Inc.; Baili-Bio (Chengdu) Pharmaceutical Co., Ltd.

Recruiting

A Study of BL-M02D1 in Patients With Locally Advanced or Metastatic Gastrointestinal Tumors or Other Solid Tumors

Solid Tumor | Locally Advanced or Metastatic Digestive Tract Tumors

China
BioNTech SE
Genmab

Recruiting

Safety and Preliminary Efficacy of BNT314 With or Without an Immune Checkpoint Inhibitor in Cancer Patients With Malignant Solid Tumors

Advanced Malignant Solid Tumor

United States, United Kingdom
Shanghai Virogin Biotech Co., Ltd.

Recruiting

A Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Biologic Effect of VG2025 in Patients With Solid Tumors

Advanced Malignant Solid Tumor

China
Sun Yat-sen University
First Affiliated Hospital, Sun Yat-Sen University; Sixth Affiliated Hospital...

Unknown

Prospective Screening Programme for Malignant Tumors

Malignant Tumor | Hematologic Tests

China
C17 Council

Completed

Phase I Dose Finding Study for Melatonin in Pediatric Oncology Patients With Relapsed Solid Tumors

Relapsed Malignant Solid Tumor

Canada
Unity Health Toronto

Unknown

EUS-FNB vs. Single-incision Needle-knife (SINK) Biopsy for Gastrointestinal SELs

Gastrointestinal Neoplasms | Gastrointestinal Stromal Tumors | Disorder of Upper Gastrointestinal Tract

Canada
Xijing Hospital

Not yet recruiting

Comparative Study of 99mTc-FAPI SPECT/CT and 68Ga-FAPI PET/CT

99mTc-FAPI-positive Gastrointestinal Tumor
Fudan University

Recruiting

Efficacy and Safety of Pyrotinib in HER2 Positive Gastrointestinal Tumors

Effect of Drug | Gastrointestinal Tumor

China
SCRI Development Innovations, LLC
Ipsen

Terminated

Study of Lanreotide in Patients With Metastatic Gastrointestinal Neuroendocrine Tumors Who Are Undergoing Liver-directed Radioembolization With Yttrium-90 Microspheres

Gastrointestinal Neoplasms | Neuroendocrine Tumors | Carcinoid Tumors

United States
Peking University People's Hospital

Recruiting

Clinical Research of Drug Holiday Based on MRD Detection in GIST Patients at High Risk of Recurrence

Gastrointestinal Stromal Tumors

China
West China Hospital

Recruiting

The Application of Novel Oncolytic Virus in Late Stage Solid Tumors

Malignant Tumor

China
Xinqiao Hospital of Chongqing

Recruiting

A Real-world Study of the Efficacy and Safety of ICIs as First-line Therapy for Advanced Malignancies

Artificial Intelligence | Malignant Tumor | Immunotherapy

China
Susan Chi, MD
Bristol-Myers Squibb; Epizyme, Inc.

Recruiting

Tazemetostat+Nivo/Ipi in INI1-Neg/SMARCA4-Def Tumors

Chordoma | Epithelioid Sarcoma | Atypical Teratoid Rhabdoid Tumor | INI1 (SMARCB1)-Deficient Primary CNS Malignant Tumors | SMARCA4-deficient Primary CNS Malignant Tumors | Malignant Rhabdoid Tumor (MRT) | Rhabdoid Tumor of the Kidney (RTK)

United States
Assistance Publique - Hôpitaux de Paris
Institut National de Recherche en Informatique et en Automatique

Unknown

Liver Resection Modeling (LRM)

Cirrhosis | Benign Liver Tumor | Malignant Tumor Liver
National Cancer Institute (NCI)

Terminated

EF5 and Motexafin Lutetium in Detecting Tumor Cells in Patients With Abdominal or Non-Small Cell Lung Cancer

Fallopian Tube Cancer | Small Intestine Lymphoma | Recurrent Pancreatic Cancer | Stage III Pancreatic Cancer | Stage IV Pancreatic Cancer | Stage IV Ovarian Epithelial Cancer | Stage IV Ovarian Germ Cell Tumor | Primary Peritoneal Cavity Cancer | Stage IIIA Non-small Cell Lung Cancer | Stage IIIB Non-small... and other conditions

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Genetic Analysis Using Blood or Bone Marrow From Participants With Neuroblastoma or Noncancerous Conditions

Recurrent Neuroblastoma | Localized Resectable Neuroblastoma | Localized Unresectable Neuroblastoma | Regional Neuroblastoma | Stage 4 Neuroblastoma

United States
Akeso

Not yet recruiting

A Study to Evaluate the Safety, Tolerance, Pharmacokinetics, and Preliminary Antineoplastic Activity of AK132 in Advanced Malignant Solid Tumor

Advanced Malignant Solid Tumor

China
GE Healthcare

Recruiting

A Study to Evaluate GEH200520/GEH200521 (18F) Safety and Tolerability When Used for PET Scans in Patients With Solid Tumour Malignancies

Oncology | Malignant Solid Tumor

Netherlands
SUNHO（China）BioPharmaceutical CO., Ltd.

Recruiting

A Clinical Trial to Evaluate the Effect of IAE0972 in Patients With Advanced Malignant Solid Tumors.

Advanced Malignant Solid Tumor

China
Sir Run Run Shaw Hospital
Hangzhou Neoantigen Therapeutics Co., Ltd.

Recruiting

Clinical Study of a Personalized Neoantigen Cancer Vaccine Combined With Anti-PD-1 and RFA in Patients With Solid Tumors

Advanced Malignant Solid Tumor

China
CNBG-Virogin Biotech (Shanghai) Ltd.

Recruiting

Clinical Study of VG161 in Subjects With Advanced Malignant Solid Tumors

Advanced Malignant Solid Tumor

China
Molecular Partners AG

Terminated

First-in-human Safety and Tolerability of MP0317 in Patients With Relapsed/Refractory Advanced Solid Tumors

Advanced Malignant Solid Tumor

Netherlands, France
Innovative Cellular Therapeutics Co., Ltd.
Anhui Provincial Cancer Hospital

Not yet recruiting

CART Therapy in Digestive System Tumors

Malignant Neoplasms of Digestive Organs

China
University Hospital, Lille
Ministry of Health, France

Terminated

Rates DMBT1 ( Glycoprotein) in Sputum of CF Patients With Pseudomonas Aeruginosa (DMBT1)

Malignant Brain Tumor

France
Xinhua Hospital, Shanghai Jiao Tong University...
CNOG-MC001 Collaborative Group

Completed

National Wide Cross-sectional Study in Paediatric Central Nervous System Tumours in China -- the CNOG-MC001 Registry

Pediatric Brain Tumor | Malignant Brain Tumor | Tumors, Central Nervous System | Benign Brain Tumor

China
National Cancer Institute (NCI)

Active, not recruiting

Isotretinoin With or Without Dinutuximab, Aldesleukin, and Sargramostim Following Stem Cell Transplant in Treating Patients With Neuroblastoma

Recurrent Neuroblastoma | Localized Resectable Neuroblastoma | Localized Unresectable Neuroblastoma | Regional Neuroblastoma | Stage 4S Neuroblastoma | Stage 4 Neuroblastoma

United States, Canada, Australia, New Zealand, Puerto Rico
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Comparing Two Different Myeloablation Therapies in Treating Young Patients Who Are Undergoing a Stem Cell Transplant for High-Risk Neuroblastoma

Recurrent Neuroblastoma | Localized Resectable Neuroblastoma | Localized Unresectable Neuroblastoma | Regional Neuroblastoma | Stage 4S Neuroblastoma | Stage 4 Neuroblastoma

United States, Canada, Australia, New Zealand, Puerto Rico, Switzerland
Massachusetts General Hospital
Boehringer Ingelheim; Incyte Corporation

Recruiting

Pemigatinib + Afatinib in Advanced Refractory Solid Tumors

Cholangiocarcinoma | Advanced Solid Tumor | Metastatic Solid Tumor | Unresectable Solid Tumor

United States
Xueding Wang
Sun Yat-sen University

Unknown

A Retrospective Pharmacokinetics and Pharmacogenomics Research of Imatinib in Gastrointestinal Stromal Tumor Treatment

Gastrointestinal Stromal Tumors | Somatic Mutation | Plasma Concentration | Germline Mutation

China
ABM Therapeutics Shanghai Company Limited

Recruiting

A Study of ABM-1310 in Patients With BRAF V600-Mutant Relapsed and Drug Resistant Primary Malignant Brain Tumors

Primary Malignant Brain Tumor

China
Masaryk Memorial Cancer Institute

Unknown

Acupuncture as the Therapeutic Modalities of Acute Toxicity in the Radiotherapy of Head and Neck Tumors

Malignant Tumor of Soft Tissue of Head, Face and Neck

Czechia
Asan Medical Center

Unknown

A Randomized Phase II Open Label Study to Compare the Safety and Efficacy of Subcutaneous Dalteparin Versus Direct Oral Anticoagulants for Cancer-associated Venous Thromboembolism (PRIORITY)

Stomach Cancer | Hepatocellular Carcinoma | Pancreatic Cancer | Esophageal Cancer | Duodenal Cancer | Esophagogastric Junction Cancer | Cancer-associated Thrombosis | Ampulla of Vater Cancer | Malignant Gastrointestinal Stromal Tumor | Biliary Cancer (Cholangiocarcinoma, Gall Bladder Cancer)

Korea, Republic of
Jinling Hospital, China
National Natural Science Foundation of China

Unknown

Gastrointestinal Postoperative Early Enteral Nutrition: Immuno-enhanced Versus Standard Early Enteral Nutrition (ISEEN)

Gastrointestinal Malignant

China
Gustave Roussy, Cancer Campus, Grand Paris

Completed

Temozolomide in Association With Topotecan in Refractory or Relapsed Malignant Tumors in Children and Adolescents

Malignant Tumors | Refractory Tumors

France
Frontier Medicines Corporation

Recruiting

A Study Evaluating FMC-376 in Participants With KRAS G12C Mutated Solid Tumors (PROSPER)

Colorectal Cancer | Pancreatic Cancer | Non Small Cell Lung Cancer | Metastatic Solid Tumor | Solid Tumor, Adult | Unresectable Solid Tumor | KRAS G12C | Advanced Solid Tumors With KRAS G12C Mutations

United States
Kliniken Ludwigsburg-Bietigheim gGmbH

Terminated

Endoscopic Full Thickness Resection of Gastric Subepithelial Tumors (FROST)

Gastrointestinal Stromal Tumors | Gastric Neoplasms

Germany
National Cancer Institute (NCI)

Active, not recruiting

Testing Treatment With Ipilimumab and Nivolumab Compared to Treatment With Ipilimumab Alone in Advanced Melanoma

Unresectable Cutaneous Melanoma | Unresectable Melanoma | Clinical Stage III Cutaneous Melanoma AJCC v8 | Melanoma of Unknown Primary | Mucosal Melanoma | Clinical Stage IV Cutaneous Melanoma AJCC v8

United States
M.D. Anderson Cancer Center

Withdrawn

Chemotherapy and Donor Stem Transplant for the Treatment of Patients With High Grade Brain Cancer

Malignant Glioma | Medulloblastoma | Anaplastic Ependymoma | Recurrent Malignant Glioma | Recurrent Medulloblastoma | Atypical Teratoid/Rhabdoid Tumor | Primitive Neuroectodermal Tumor | Choroid Plexus Carcinoma | Recurrent Atypical Teratoid/Rhabdoid Tumor | Malignant Brain Neoplasm | Central Nervous System... and other conditions

United States

Clinical Trials on Unresectable Malignant Gastrointestinal Stromal Tumor

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Argentina

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations