Clinical Trials on Unresectable Metastatic Colo-rectal Cancer

Total 15738 results

National Cancer Institute, Egypt

Recruiting

Reversal of a Defunctioning Ileostomy 3 Weeks After the Index Operation, RCT

Colo-rectal Cancer

Egypt
Cancer Institute and Hospital, Chinese Academy...

Recruiting

The Efficacy and Safety of Modified XELOX(mXELOX) Plus Cetuximab vs FOLFOX Plus Cetuximab in RAS and BRAF WT mCRC Pts

Colo-rectal Cancer

China
Shanghai Zhongshan Hospital

Recruiting

Fruquintinib as a Maintenance Therapy Following First-line Treatment for Metastatic Colorectal Cancer

Colo-rectal Cancer

China
Niguarda Hospital

Completed

Total Neoadjuvant Treatment Without Surgery For Locally Advanced Rectal Cancer (NO-CUT)

Colo-rectal Cancer

Italy
George Albert Fisher
Bristol-Myers Squibb

Terminated

A Phase 1-2 Trial of Cetuximab in Combination With Oxaliplatin, Capecitabine, and Radiation Therapy Followed by Surgery for Locally-advanced Rectal Cancer

Rectal Cancer | Colo-rectal Cancer

United States
University of Oxford
National Institute for Health Research, United Kingdom; Imunon

Withdrawn

PanDox: Targeted Doxorubicin in Pancreatic Tumours (PanDox)

Pancreatic Cancer Metastatic | Pancreatic Ductal Adenocarcinoma | Pancreatic Cancer Stage IV | Pancreatic Cancer Non-resectable

United Kingdom
Epigenomics, Inc

Active, not recruiting

CRC Detection Reliable Assessment With Blood (CRC-DRAW)

Gastrointestinal Neoplasms | Colonic Diseases, Functional | Intestinal Neoplasms | Rectal Diseases | Colorectal Cancer | Adenoma | Rectal Cancer | Polyps | Colon Cancer | Colon Disease | Colon Polyp | Intestinal Disease | Colon Lesion | Colon Neoplasm | Adenomas Colon | Rectal Polyp

United States
National Cancer Institute (NCI)

Recruiting

Adding Nivolumab to Usual Treatment for People With Advanced Stomach or Esophageal Cancer, PARAMUNE Trial

Clinical Stage III Gastric Cancer AJCC v8 | Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8 | Clinical Stage IV Gastric Cancer AJCC v8 | Clinical Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8 | Metastatic Gastric Adenocarcinoma | Metastatic Gastroesophageal Junction... and other conditions

United States
University Hospital, Linkoeping

Recruiting

Evaluation of Metastatic Disease and Oncological Treatment in Patients With Colon Cancer Using Zebra Fish Avatars (ZEBRA-COLON)

Colon Cancer

Sweden
Yonsei University

Unknown

Effects of Iloprost on Pulmonary Oxygenation in Obese Patients During One-lung Ventilation

Pulmonary Infection | Lung Cancer (Including Metastatic Cancer)
Memorial Sloan Kettering Cancer Center

Active, not recruiting

Hepatic Arterial Infusion With Floxuridine and Dexamethasone Combination With Chemotherapy With/Without Bevacizumab for Hepatic Metastases From Colorectal Cancer

Rectal Cancer | Colon Cancer | Hepatic Metastases

United States
Jazz Pharmaceuticals

Recruiting

A Study of JZP815 Oral Capsules in Adult Participants With Advanced or Metastatic Solid Tumors Harboring Mitogen Activated Protein Kinase (MAPK) Pathway Alterations to Investigate the Safety, Dosing, and Antitumor Activity of JZP815

Solid Tumor | Metastatic Cancer | Advanced Cancer

United States
Yonsei University

Not yet recruiting

First-line Trastuzumab, Gemcitabine, Cisplatin and Nivolumab in Advanced HER2- Positive Biliary Tract Cancer: a Multicenter, Open-label, Single-arm Phase Ib/II Trial (HERBOT)

HER2 Positive Advanced/Metastatic/Nonresectable Biliary Tract Cancer

Korea, Republic of
National Cancer Institute (NCI)

Recruiting

Testing the Combination of Two Anti-cancer Drugs, DS-8201a and AZD6738, for The Treatment of Patients With Advanced Solid Tumors Expressing the HER2 Protein or Gene, The DASH Trial

Anatomic Stage III Breast Cancer AJCC v8 | Anatomic Stage IV Breast Cancer AJCC v8 | Advanced Malignant Solid Neoplasm | Unresectable Malignant Solid Neoplasm | Stage III Uterine Corpus Cancer AJCC v8 | Stage IV Uterine Corpus Cancer AJCC v8 | Metastatic Malignant Solid Neoplasm | Clinical Stage... and other conditions

United States
Jiangxi Provincial Cancer Hospital

Recruiting

High- and Low-dose Radiotherapy Combined With Envafolimab for Metastatic Solid Tumor (ST-CR01)

Metastatic Cancer

China
University of Pittsburgh

Recruiting

Ubuntu - I Am Because We Are (Doulas-AC)

Metastatic Cancer

United States
Gustave Roussy, Cancer Campus, Grand Paris
Roche Pharma AG

Recruiting

Implementing Precision Medicine in cOmmunity HospiTALs (PRISM-POrTAL)

Metastatic Cancer

France
Milton S. Hershey Medical Center

Completed

Exercise Therapy in Radiation Therapy (EXERT)

Metastatic Cancer

United States
Hoffmann-La Roche

Completed

Study to Explore the Mechanism of Acquired Immune Escape In Participants With Metastatic Cancer Progressing on CPI Therapy

Neoplasms

United States, France, Spain, Korea, Republic of, United Kingdom
Alliance Foundation Trials, LLC.
Patient-Centered Outcomes Research Institute; Mayo Clinic; Dana-Farber Cancer... and other collaborators

Active, not recruiting

Electronic Patient Reporting of Symptoms During Cancer Treatment (PRO-TECT)

Metastatic Cancer

United States
National Institutes of Health Clinical Center (CC)

No longer available

Single Patient Protocol: A Phase II Study Using the Administration of Autologous T-Cells Genetically Engineered to Express T-Cell Receptors Reactive Against Mutated Neoantigens in a Patient With Metastatic Cancer Plus the Administration of Pembrolizumab
Jonsson Comprehensive Cancer Center

Completed

Radiation Therapy Following Surgery to Remove Brain Metastases

Metastatic Cancer

United States
Eli Lilly and Company

Completed

A Study of LY3007113 in Participants With Advanced Cancer

Metastatic Cancer

United States
Viatar LLC

Unknown

Evaluation of Viatar™ Oncopheresis System in Removing CTC From Whole Blood

Metastatic Cancer
Eli Lilly and Company

Completed

A Study of LY2624587 in Patients With Advanced Cancer

Metastatic Cancer

United States
Hospital Universitari de Bellvitge
Instituto de Salud Carlos III

Terminated

Resection vs no Resection of the Primary in Colorectal Cancer With Unresectable Metastases (CCRe-IV)

Colonic Cancer | Unresectable Metastasis Originating in Colonic Cancer

Spain
Corporacion Parc Tauli

Recruiting

PREHABILITATION RECTAL CANCER DURING ADJUVANCY VS BEFORE SURGERY (prehab-cspt)

Colo-rectal Cancer

Spain
Vejle Hospital

Active, not recruiting

Single-stapled Double Purse-string Technique for Colorectal Anastomosis

Colo-rectal Cancer

Denmark
Check-Cap Ltd.

Completed

Safety,Usability and Compliance of Using C-Scan System for Providing Information on Colonic Polypoid Lesions and Masses (C-Scan)

Colo-rectal Cancer

United States
Roswell Park Cancer Institute
National Cancer Institute (NCI)

Completed

Problem Solving Skills Training in Adult Cancer Survivors: Bright IDEAS-AC

Colo-rectal Cancer

United States
Check-Cap Ltd.

Completed

Development Study of Check-Cap Imaging System in Healthy Volunteers

Colo-rectal Cancer

Israel
Exact Sciences Corporation

Completed

Blood Collection Sub-Study for CRC Screening in Individuals 45-49 at Average Risk for CRC.

Colo-rectal Cancer

United States
Richard Crosby
Centers for Disease Control and Prevention

Completed

Assessing Repeat Fit Testing for CRC (ARFT)

Colo-rectal Cancer

United States
Abramson Cancer Center at Penn Medicine

Recruiting

A Phase I Dual Dose Escalation Study of Radiation and Nab-Paclitaxel in Patients With Unresectable and Borderline Resectable Pancreatic Cancer

Locally Advanced Unresectable Pancreatic Cancer Treated With Chemoradiotherapy | Borderline Resectable Pancreatic Cancer Treated With Chemoradiotherapy

United States
Michael Lidsky, M.D.

Withdrawn

Hepatic Artery Infusion (HAI) Program at Duke University

Intrahepatic Cholangiocarcinoma | Liver Cancer | Metastatic Colon Cancer
The Rogosin Institute
Vital Systems Inc.

Completed

Open-Label Phase 2 Efficacy Trial of Cancer Macrobeads in Patients With Treatment-Resistant Pancreatic/Colorectal Cancer (Macrobead)

Colorectal Cancer Metastatic | Pancreatic Adenocarcinoma Metastatic | Pancreatic Adenocarcinoma Non-resectable

United States
National Cancer Institute (NCI)

Recruiting

Testing the Safety and Efficacy of the Addition of A New Anti-cancer Drug, ZEN003694, to Chemotherapy Treatment (Etoposide and Cisplatin) for Adult and Pediatric Patients (12-17 Years) With NUT Carcinoma

Metastatic NUT Carcinoma | Unresectable NUT Carcinoma | Advanced NUT Carcinoma

United States
Letolab

Not yet recruiting

Phase II Clinical Study of LTC004 in Patients With Advanced Sarcoma

Unresectable or Metastatic Sarcoma
M.D. Anderson Cancer Center

Recruiting

Cetuximab for the Treatment of Advanced Unresectable or Metastatic Chordoma

Chordoma | Metastatic Chordoma | Unresectable Chordoma

United States
National Cancer Institute (NCI)

Terminated

Phase I Study of Cetuximab With RO4929097 in Metastatic Colorectal Cancer

Recurrent Colon Carcinoma | Recurrent Rectal Carcinoma | Stage IVA Colon Cancer | Stage IVA Rectal Cancer | Stage IVB Colon Cancer | Stage IVB Rectal Cancer | Colon Mucinous Adenocarcinoma | Colon Signet Ring Cell Adenocarcinoma | Rectal Mucinous Adenocarcinoma | Rectal Signet Ring Cell Adenocarcinoma

United States
Ohio State University Comprehensive Cancer Center

Completed

2 Phase Comparison of Pre-operative CT and PET Images for Metastatic Colorectal Cancer

Recurrent Colon Cancer | Recurrent Rectal Cancer | Stage IV A Bladder Cancer | Stage IV A Rectal Cancer | Stage IV B Colon Cancer | Stage IV B Rectal Cancer

United States
University of Florida
National Cancer Institute (NCI)

Completed

The United States Healthy Living Study

Colo-rectal Cancer

United States
Cascadian Therapeutics Inc.

Completed

A Trial of PX-12 in Patients With a Histologically or Cytologically Confirmed Diagnosis of Advanced or Metastatic Cancer

Metastatic Cancer | Advanced Cancer

United States
PharmAbcine

Completed

Phase I Trial of Tanibirumab in Advanced or Metastatic Cancer

Metastatic Cancer | Advanced Cancer

Korea, Republic of
Centre Leon Berard
Bayer

Active, not recruiting

A Retro-/Prospective, Non-interventional, Cohort Study in Adult Patients With Locally Advanced or Metastatic Tumors With a Neurotrophic Tyrosine Receptor Kinase (NTRK) Gene Fusion, Treated With Larotrectinib (LAROTRACKING)

Metastatic Cancer | Solid Tumor, Adult | Locally Advanced Solid Tumor

France
City of Hope Medical Center
National Cancer Institute (NCI)

Withdrawn

Perception of Cure Among Patients With Metastatic Cancer

Hematopoietic and Lymphoid Cell Neoplasm | Metastatic Malignant Solid Neoplasm

United States
University of Kansas Medical Center

Not yet recruiting

Dose-escalation Study of Ultra-high Dose Ablative Radiosurgery With Immunotherapy for Bulky Metastatic Cancer Patients

Solid Tumor

United States
The Belgian Society of Medical Oncology
Illumina, Inc.; OncoDNA; PierianDx

Recruiting

A Study to Examine the Clinical Value of Comprehensive Genomic Profiling Performed by Belgian NGS Laboratories: a Belgian Precision Study of the BSMO in Collaboration With the Cancer Centre (BALLETT)

Solid Tumor | Metastatic Cancer

Belgium
NCIC Clinical Trials Group
Assistance Publique - Hôpitaux de Paris; National Cancer Institute (NCI); Cancer... and other collaborators

Completed

Single vs Multiple-Fraction Therapy in Treating Patients With Previously Irradiated Painful Bone Metastases

Pain | Metastatic Cancer

Canada
Radiation Therapy Oncology Group
National Cancer Institute (NCI); NRG Oncology

Completed

Image-Guided Radiosurgery or Stereotactic Body Radiation Therapy in Treating Patients With Localized Spine Metastasis

Pain | Metastatic Cancer

United States, Canada, Israel

Clinical Trials on Unresectable Metastatic Colo-rectal Cancer

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