Clinical Trials on Urea Cycle Disorder

Total 145006 results

Floor Backes
Eisai Inc.

Completed

Lenvatinib and Weekly Paclitaxel for Patients With Recurrent Endometrial or Ovarian Cancer

Fallopian Tube Carcinoma | Recurrent Endometrial Cancer | Primary Peritoneal Carcinoma | Recurrent Ovarian Cancer

United States
University Hospital, Angers

Completed

Comparison of Different PEEP Titration Strategies Using Electrical Impedance Tomography in Patients With ARDS (DELTA)

Acute Lung Injury | ARDS (Acute Respiratory Distress Syndrome) | Positive End Expiratory Pressure (PEEP) | Electrical Impedance Tomography (EIT)

France
Enzyvant Therapeutics GmBH
National Institute of Allergy and Infectious Diseases (NIAID); Eunice Kennedy... and other collaborators

Completed

Thymus Transplantation With Immunosuppression (884)

DiGeorge Syndrome | DiGeorge Anomaly | Complete DiGeorge Anomaly | Complete DiGeorge Syndrome

United States
Rush University Medical Center

Completed

Early PP With HFNC Versus HFNC in COVID-19 Induced Moderate to Severe ARDS

Acute Respiratory Distress Syndrome | Corona Virus Infection | High Flow Nasal Cannula | Prone Positioning

United States
Blueprint Medicines Corporation
Analysis Group, Inc.

Completed

Retrospective Study Assessing the Effect of Avapritinib Versus Best Available Therapy in Patients With AdvSM

Mast Cell Leukemia | Aggressive Systemic Mastocytosis | Advanced Systemic Mastocytosis | Systemic Mastocytosis With an Associated Hematological Neoplasm

United States, Austria, Germany, Spain, United Kingdom
Central Hospital, Nancy, France

Completed

Efficacy of Infusions of MSC From Wharton Jelly in the SARS-Cov-2 (COVID-19) Related Acute Respiratory Distress Syndrome (MSC-COVID19)

COVID19 ARDS

France
Integra LifeSciences Corporation

Terminated

Diabetic Foot Ulcer Study Comparing Cytal Wound Matrix 1-Layer to Standard of Care

Diabetes Mellitus, Type 2 | Diabetes | Diabetic Foot | Diabetes Mellitus, Type 1

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Peptide Vaccinations to Treat Patients With Low-Risk Myeloid Cancers

Acute Myeloid Leukemia (AML) | Myelodysplastic Syndrome (MDS) | Chronic Myeloid Leukemia (CML)

United States
Abramson Cancer Center of the University of Pennsylvania

Completed

Optional Sub-study to Intraoperative Imaging With ICG Registry

Lung, Prostate, Breast, Colon, Pancreatic, Renal, Bladder,Thyroid, Ovarian, Head and Neck,GI (Foregut - Esophagus),GI (Midgut) Cancer | Cancer of the Ovarian, Head and Neck,GI (Foregut - Esophagus),GI (Midgut), Sarcoma Cancer | Cancer of Neuro-onc, Parathyroid, Desmoid Tumors, Melanoma...

United States
Assistance Publique - Hôpitaux de Paris

Completed

FX06 to Rescue Acute Respiratory Distress Syndrome During Covid-19 Pneumonia (FX-COVID)

Pneumonia | Covid19 | Ards

France
University Hospital, Strasbourg, France

Completed

Metabolic Efficiency of Combined Pancreatic Islet and Lung Transplant for the Treatment of End-Stage Cystic Fibrosis (PIM)

Cystic Fibrosis | Insulin-dependent Diabetes | Diabetes Related Cystic Fibrosis

France
Bispebjerg Hospital

Completed

MRI for the Early Evaluation of Acute Intracerebral Hemorrhage

Brain Neoplasms | Cerebral Hemorrhage | Intracranial Arteriovenous Malformations | Intracranial Hemorrhage, Hypertensive

Denmark
CanariaBio Inc.

Terminated

The Safety and Antitumor Activity of the Combination of Oregovomab and Hiltonol in Recurrent Advanced Ovarian Cancer

Ovary Cancer | Ovarian Cancer Stage IV | Neoplasms, Ovarian | Ovarian Cancer Stage III | Ovarian Cancer Recurrent | Cancer of Ovary

United States
Unity Health Toronto
Defence Research and Development Canada

Unknown

RIC as an Adjunct Therapy for Severe COVID-19 Disease: a Prospective Randomized Pilot Study

COVID | Ischemia Limb | Acute Respiratory Distress Syndrome | Acute Lung Injury | Corona Virus Infection
Xiaoxiang Chen

Unknown

Efficacy and Safety of Niraparib Combined With Bevacizumab in Platinum Refractory/Resistant Recurrent Ovarian Cancer (AVANIRA3)

Neoplasms | Neoplasms by Histologic Type | Urogenital Neoplasms | Neoplasms by Site | Carcinoma | Neoplasms, Glandular and Epithelial | Genital Neoplasms, Female | Endocrine System Diseases | Ovarian Diseases | Adnexal Diseases | Gonadal Disorders | Endocrine Gland Neoplasms | Ovarian Neoplasms | Fallopian Tube Neoplasms and other conditions

China
Hospital Sírio-Libanês
Hospital Israelita Albert Einstein; Ache Laboratorios Farmaceuticos S.A.; Hospital... and other collaborators

Terminated

COVID-19-associated ARDS Treated With Dexamethasone: Alliance Covid-19 Brasil III (CoDEX)

Coronavirus Infection | Pneumonia, Viral | Acute Respiratory Distress Syndrome

Brazil
Azienda USL Toscana Nord Ovest
Azienda Ospedaliero, Universitaria Pisana; Azienda Ospedaliera Universitaria... and other collaborators

Unknown

Ruxolitinib for the Treatment of Acute Respiratory Distress Syndrome in Patients With COVID-19 Infection (RESPIRE)

Severe Acute Respiratory Syndrome Coronavirus 2
Universitätsmedizin Mannheim

Unknown

Evaluation of Novel Lung Function Parameters in Patients With Interstitial Lung Disease (ILD)

Idiopathic Pulmonary Fibrosis | Interstitial Lung Disease | Sarcoidosis | Pulmonary Healthy Controls | Non-specific Interstitial Pneumonia | Granulomatosis With Polyangiitis (Wegener's Disease)

Germany
Gynecologic Oncology Group
National Cancer Institute (NCI)

Withdrawn

Vaccine Therapy and OPT-821 or OPT-821 Alone in Treating Patients With Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cancer in Complete Remission

Ovarian Cancer | Fallopian Tube Cancer | Primary Peritoneal Cavity Cancer
University Hospital Schleswig-Holstein
University College, London; Academisch Medisch Centrum - Universiteit van Amsterdam... and other collaborators

Completed

Continuous Regional Analysis Device for Neonate Lung (CRADL)

Acute Respiratory Distress Syndrome | Infant Respiratory Distress Syndrome | Acute Bronchiolitis

Netherlands, Finland, Cyprus
Wills Eye
University of Medicine and Dentistry of New Jersey

Terminated

Treatment of Port-wine Mark in Sturge-Weber Syndrome Using Topical Timolol

Sturge Weber Syndrome | Port-wine Mark

United States
Rigshospitalet, Denmark

Terminated

Lung and Systemic Inflammation in the Critically Ill Patient

Sepsis | Acute Respiratory Distress Syndrome (ARDS) | Systemic Inflammatory Response Syndrome (SIRS)

Denmark
Ole Thorlacius-Ussing, MD, DMSc, Professor of Surgery

Unknown

Venous Thromboembolic Complications in Ovarian Cancer

Ovarian Neoplasms | Ovarian Cancer | Deep Vein Thrombosis | Venous Thromboembolism | Lung Embolism

Denmark
Genzyme, a Sanofi Company

Withdrawn

ILX-295501 in Treating Patients With Stage III or Stage IV Ovarian Cancer That Has Not Responded to Previous Treatment

Ovarian Cancer | Fallopian Tube Cancer | Metastatic Cancer | Primary Peritoneal Cavity Cancer

United States
Novartis Pharmaceuticals

Completed

Efficacy, Safety and Tolerability of ACZ885 in Pediatric Patients With the Following Cryopyrin-associated Periodic Syndromes: Familial Cold Autoinflammatory Syndrome, Muckle-Wells Syndrome, or Neonatal Onset Multisystem Inflammatory Disease

Familial Cold Autoinflammatory Syndrome | Muckle-Wells Syndrome | Neonatal Onset Multisystem Inflammatory Disease | Cryopyrin-associated Periodic Syndromes

Germany, France, Belgium, Canada, Spain, Switzerland, United Kingdom
Montefiore Medical Center

Completed

Effect of Supine or Prone Position After Caesarean Birth

Transient Tachypnea of the Newborn | Respiratory Distress | Delayed Transition of the Newborn | Persistent Pulmonary Hypertension

United States
Indonesia University

Unknown

The Effect of β-Carotene, Vitamin D3 and Zinc on Hyaline Membrane Disease and Feeding Intolerance in Premature Neonates

Hyaline Membrane Disease | Necrotizing Enterocolitis of Newborn

Indonesia
Mononuclear Therapeutics Ltd.
Chinese University of Hong Kong; China Spinal Cord Injury Network

Unknown

Feasibility and Safety of Umbilical Cord Blood Transfusion in the Treatment of Neonatal Cerebral Ischemia and Anemia

Anemia, Neonatal | Hypoxic-Ischemic Encephalopathy | Hypoxia Neonatal | Cerebral Ischemia of Newborn

Hong Kong
Johann Wolfgang Goethe University Hospital

Unknown

Susceptibility to Infections, Tumor Risk and Liver Disease in Patients With Ataxia Telangiectasia

Ataxia Telangiectasia

Germany
First Affiliated Hospital Xi'an Jiaotong University
Xijing Hospital; Shaanxi Provincial People's Hospital; Second Affiliated Hospital... and other collaborators

Unknown

Effect of Erythropoietin in Premature Infants on White Matter Lesions and Neurodevelopmental Outcome

Cerebral Palsy | Intracranial Hemorrhages | Premature Infants | Periventricular Leukomalacia

China
NICHD Neonatal Research Network
Canadian Institutes of Health Research (CIHR); National Center for Research... and other collaborators

Terminated

Early Inhaled Nitric Oxide for Respiratory Failure in Newborns (Early iNO)

Respiratory Insufficiency | Hypertension, Pulmonary | Pneumonia, Aspiration | Persistent Fetal Circulation Syndrome | Respiratory Distress Syndrome, Newborn | Infant, Newborn

United States
NICHD Neonatal Research Network
National Center for Research Resources (NCRR)

Completed

In Utero Magnesium Sulfate Exposure: Effects on Extremely-Low-Birth-Weight Infants (MgSO4)

Cerebral Palsy | Intracranial Hemorrhages | Infant, Small for Gestational Age | Infant, Premature | Leukomalacia, Periventricular | Infant, Low Birth Weight | Infant, Newborn

United States
Institute Of Cardiology & Internal Diseases, Kazakhstan
Merck Sharp & Dohme LLC; Synergy Research Group

Unknown

Open-Label Efficacy and Safety Study of the Elbasvir/ Grazoprevir Fixed Dose Combination Patients With Chronic HCV GT1b

Metabolic Syndrome | Fibrosis, Liver | Cirrhoses, Liver | Chronic Hepatitis C Genotype 1B

Kazakhstan
Colorado State University
National Institute for Biomedical Imaging and Bioengineering (NIBIB)

Completed

Electrical Impedance Imaging of Patients on Mechanical Ventilation

Pneumothorax | Emphysema | Hyperinflation | Acute Respiratory Distress Syndrome | Pulmonary Edema | Pleural Effusion | Atelectasis | Pulmonary Contusion

United States
Baylor College of Medicine
Novartis Pharmaceuticals

Withdrawn

Adjunctive Everolimus (RAD 001) Therapy for Epilepsy in Children With Sturge-Weber Syndrome (SWS)

Sturge Weber Syndrome

United States
National Cancer Institute (NCI)

Completed

Phase II Study of Clinical Activity of Pegaspargase in Women With Relapsed or Refractory Epithelial Ovarian Cancer, Fallopian Tube Cancer, and/or Primary Peritoneal Cancer

Ovarian Neoplasms | Fallopian Tube Neoplasms | Primary Peritoneal Neoplasms

United States
Southwest Oncology Group
National Cancer Institute (NCI); Eastern Cooperative Oncology Group

Terminated

S9624 Ifosfamide in Treating Patients With Meningeal Tumors

Chondrosarcoma | Adult Rhabdomyosarcoma | Adult Fibrosarcoma | Adult Leiomyosarcoma | Adult Malignant Meningioma | Adult Brain Malignant Hemangiopericytoma

United States, Australia, Peru, Puerto Rico
University Hospital, Clermont-Ferrand

Completed

Influence of Acute Respiratory Distress Syndrome (ARDS) and Severe Sepsis on sRAGE Levels in ICU Patients

Septic Shock | Acute Respiratory Distress Syndrome | Acute Lung Injury | Severe Sepsis | Mechanical Ventilation

France
Medical Research Council

Completed

Carboplatin and Paclitaxel With or Without Bevacizumab in Treating Patients With Newly Diagnosed Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cavity Cancer

Ovarian Cancer | Fallopian Tube Cancer | Primary Peritoneal Cavity Cancer

France, Australia, United Kingdom, Norway, Germany
Chiltern Pesquisa Clinica Ltda

Completed

Immunogenicity, Safety, and Tolerability of an MF59-Adjuvanted Versus Non-Adjuvanted Influenza Vaccines in Patients With Chronic Pulmonary Disease, Chronic Heart Disease, or Diabetes Mellitus

Diabetes Mellitus | Chronic Pulmonary Disease | Chronic Heart Disease | H1N1 Influenza Virus

Brazil
Ohio State University Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

PS-341 in Treating Patients With Metastatic Neuroendocrine Tumors

Islet Cell Tumor | Gastrointestinal Carcinoid Tumor

United States
National Cancer Institute (NCI)

Completed

3-AP and Cisplatin in Treating Patients With Recurrent or Persistent Platinum-Resistant Ovarian Epithelial or Primary Peritoneal Cancer

Stage IV Ovarian Epithelial Cancer | Primary Peritoneal Cavity Cancer | Recurrent Ovarian Epithelial Cancer | Stage III Ovarian Epithelial Cancer

United States
M.D. Anderson Cancer Center
Millennium Pharmaceuticals, Inc.

Completed

PS-341 Plus Carboplatin in Platinum and Taxane Resistant Recurrent Ovarian Cancer, Primary Peritoneal Cancer, and Fallopian Tube Cancer

Ovarian Cancer | Fallopian Tube Cancer | Primary Peritoneal Cancer

United States
Canadian Immunodeficiency Research Collaborative
Pur Medical Corporation

Completed

Safety, Efficacy and Psychological Effects of Treating Antiretroviral Drug-Induced Facial Lipoatrophy With Bio-Alcamid

Human Immunodeficiency Virus | Facial Lipoatrophy

Canada
Radboud University Medical Center

Unknown

A Study of Combination of Temsirolimus (Torisel®) and Pegylated Liposomal Doxorubicin (PLD, Doxil®/Caelyx®) in Advanced or Recurrent Breast, Endometrial and Ovarian Cancer

Ovarian Cancer | Endometrial Cancer | Advanced/Recurrent Breast Cancer

Netherlands
Clarassance, Inc.
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Safety, Pk and Anti-inflammatory Effects of CC10 Protein in Premature Infants With Respiratory Distress Syndrome (RDS)

Bronchopulmonary Dysplasia | Respiratory Distress Syndrome in Premature Infant

United States
National Center for Research Resources (NCRR)
University of California, San Diego

Completed

Study of the Metabolism of Pyruvate and Related Problems in Patients With Lactic Acidemia

MELAS Syndrome | Lactic Acidosis | Mitochondrial Myopathy

United States
National Center for Complementary and Integrative...

Completed

Massage Therapy for Cancer-Related Fatigue

Breast Neoplasms | Prostatic Neoplasms | Colorectal Neoplasms | Ovarian Neoplasms

United States
Bellus Health Inc
National Institute of Neurological Disorders and Stroke (NINDS)

Completed

Cerebril™ in Patients With Lobar Hemorrhage Related to Cerebral Amyloid Angiopathy

Stroke | Neurologic Diseases, General

United States
Chunling Jiang

Not yet recruiting

Quality of Life Change in Patients Undergoing Parathyroidectomy With End-stage Renal Failure

Secondary Hyperparathyroidism | End Stage Renal Failure

Clinical Trials on Urea Cycle Disorder

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Medical Conditions

Drug Interventions

CROs by country

CROs in Algeria

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