Clinical Trials on Urea Cycle Disorder

Total 144703 results

Institut Paoli-Calmettes
Innate Pharma

Recruiting

A Phase 1 First-In-Human Study of the Anti-CD73 IPH5301 Alone or in Combination With Chemotherapy and Trastuzumab in Patients With Advanced Solid Tumors (CHANCES)

Metastatic Cancer | Metastatic Lung Cancer | Metastatic Breast Cancer | Advanced Solid Tumor | Endometrial Cancer | Metastatic Gastric Cancer | Metastatic Pancreatic Cancer | Oesophageal Cancer | Metastatic Ovary Cancer

France
Massachusetts General Hospital

Recruiting

Prostate Cancer Genetic Risk Evaluation and Screening Study (PROGRESS)

Lynch Syndrome | Genetic Predisposition to Disease | Prostate Cancer | BRCA1 Mutation | BRCA2 Mutation | Prostatic Neoplasm | ATM Gene Mutation | MMR Mutation

United States
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI); American Lebanese Syrian Associated Charities...

Recruiting

A Trial of Dabrafenib, Trametinib and Hydroxychloroquine for Patients With Recurrent LGG or HGG With a BRAF Aberration

Low Grade Glioma (LGG) of Brain With BRAF Aberration | High Grade Glioma (HGG) of the Brain With BRAF Aberration | Low Grade Glioma of Brain With Neurofibromatosis Type 1

United States
Institut Paoli-Calmettes
UNICANCER - Le Groupe génétique et cancer (GGC)

Recruiting

Genetic Predisposition to Breast and Ovarian Cancer: Prospective Study of BRCAx Gene Mutation (GENEPSO)

Breast Cancers | Ovarian Cancers

France
Mayo Clinic

Recruiting

Prospective Research Rare Kidney Stones (ProRKS) (ProRKS)

Cystinuria | Hyperoxaluria | Dent Disease | Lowe Syndrome | Adenine Phosphoribosyltransferase Deficiency

United States, Canada, Iceland, Israel
National Cancer Institute (NCI)
NRG Oncology

Active, not recruiting

Testing the Combination of Olaparib and Durvalumab, Cediranib and Durvalumab, Olaparib and Capivasertib, and Cediranib Alone in Recurrent or Refractory Endometrial Cancer Following the Earlier Phase of the Study That Tested Olaparib and Cediranib in Comparison to Cediranib Alone, and Olaparib Alone

Endometrial Mixed Cell Adenocarcinoma | Endometrial Serous Adenocarcinoma | Endometrial Undifferentiated Carcinoma | Stage IV Uterine Corpus Cancer AJCC v8 | Endometrial Adenocarcinoma | Endometrioid Adenocarcinoma

United States, Canada
University of Florida
Society for Pediatric Dermatology; Eunice Kennedy Shriver National Institute...

Completed

Antibiotic "Dysbiosis" in Preterm Infants

Bacteremia | Enterocolitis, Necrotizing | Intraventricular Hemorrhage | Chronic Lung Disease | Bronchopulmonary Dysplasia | Periventricular Leukomalacia | Ileal Perforation

United States
GOG Foundation
National Cancer Institute (NCI)

Active, not recruiting

Studying the Physical Function and Quality of Life Before and After Surgery in Patients With Stage I Cervical Cancer

Lymphedema | Cervical Adenocarcinoma | Cervical Adenosquamous Carcinoma | Cervical Squamous Cell Carcinoma | Stage IA2 Cervical Cancer AJCC v6 and v7 | Stage IB1 Cervical Cancer AJCC v6 and v7 | Stage IA1 Cervical Cancer AJCC v6 and v7

United States, Korea, Republic of, Canada
Allegheny Singer Research Institute (also known...
ElectroCore INC

Terminated

Study Assessing Vagus Nerve Stimulation in CoViD-19 Respiratory Symptoms (SAVIORII)

Respiratory Failure | COVID | Corona Virus Infection | Respiratory Distress Syndrome, Adult | SARS (Severe Acute Respiratory Syndrome) | ARDS, Human

United States
Duke University

Completed

Assessment of InfraScanner 2000™ in Detecting Subdural and Epidural Hematomas

Head Injuries, Closed | Head Trauma | Head Injuries | Craniocerebral Injuries | Crushing Skull Injury | Head Injuries, Multiple | Head Trauma,Closed | Head Trauma Injury | Head Trauma, Penetrating | Head Injury, Minor | Head Injury Major | Head Injury, Open | Injuries, Craniocerebral | Injuries, Head | Multiple Head... and other conditions

United States, Uganda
Lawson Health Research Institute

Active, not recruiting

Stereotactic Pelvic Adjuvant Radiation Therapy in Cancers of the Uterus.

Carcinosarcoma | Endometrioid Adenocarcinoma | Clear Cell Carcinoma | Serous Carcinoma | Dedifferentiated Carcinoma

Canada
National Cancer Institute (NCI)

Completed

Selumetinib in Treating Patients With Neurofibromatosis Type 1 and Cutaneous Neurofibroma

Neurofibromatosis Type 1 | Cutaneous Neurofibroma | Optic Nerve Glioma

United States
US Biotest, Inc.

Terminated

Safety and Efficacy of USB002 for Respiratory Distress Due to COVID-19

SARS-CoV-2 Infection | Respiratory Distress Syndrome, Adult | Adult Respiratory Distress Syndrome | COVID-19 Virus Infection | SARS Coronavirus 2 Infection | 2019 Novel Coronavirus Infection

United States
Mercy Medical Center

Active, not recruiting

HOT: HIPEC in Ovarian Cancer as Initial Treatment (CRS/HIPEC)

Fallopian Tube Cancer | Epithelial Ovarian Cancer | Fallopian Tube Carcinoma | Ovarian Carcinoma | Primary Peritoneal Carcinoma | Stage IV Ovarian Cancer | Stage III Ovarian Cancer

United States
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI)

Completed

Autologous T Cells With or Without Cyclophosphamide and Fludarabine in Treating Patients With Recurrent or Persistent Advanced Ovarian Epithelial Cancer, Primary Peritoneal Cavity Cancer, or Fallopian Tube Cancer (Fludarabine Treatment Closed as of 12/01/2009)

Ovarian Cancer | Fallopian Tube Cancer | Primary Peritoneal Cavity Cancer

United States
Alexandria University
Science and Technology Development Fund (STDF), ,Egypt

Completed

Safety and Effectiveness of Cyclosporin in the Management of COVID19 ARDS Patients in Alexandria University Hospital

Pulmonary Fibrosis | Cytokine Release Syndrome | COVID-19 Acute Respiratory Distress Syndrome

Egypt
EpicentRx, Inc.

Completed

RRx-001 in Lung Cancer, Ovarian Cancer and Neuroendocrine Tumors Prior to Re-administration of Platinum Based Doublet Regimens (QUADRUPLE THREAT)

Carcinoma, Non-Small-Cell Lung | Ovarian Epithelial Cancer | Neuroendocrine Tumors | Small Cell Carcinoma

United States
Instituto Venezolano de Investigaciones Cientificas

Completed

Study to Verify the Effectiveness and Safety of Isothymol or Carvacrol Compound Against SARS-CoV-2 in COVID-19 Patients

COVID-19 | COVID-19 Pneumonia | COVID-19 Respiratory Infection | COVID-19 Acute Respiratory Distress Syndrome | COVID-19 Lower Respiratory Infection

Venezuela
Hôpital Louis Mourier

Completed

Extended Prone Position Duration COVID-19-related ARDS: a Retrospective Study

Pressure Ulcer | Hypoxemic Respiratory Failure | COVID-19 Acute Respiratory Distress Syndrome | Respiratory Distress Syndrome, Acute

France
National Cancer Institute (NCI)

Terminated

Tocilizumab for Patients With Cancer and COVID-19 Disease

Hematopoietic and Lymphoid Cell Neoplasm | Malignant Solid Neoplasm | Pneumonia | Symptomatic COVID-19 Infection Laboratory-Confirmed | Severe Acute Respiratory Distress Syndrome | Pneumonitis

United States
UNC Lineberger Comprehensive Cancer Center

Completed

PET/MRI in CNS and Extra-CNS Tumors of Patients With Neurofibromatosis-1 (NF1)

Optic Glioma | Plexiform Neurofibroma | Neurofibromatosis-1

United States
VA Office of Research and Development
US Department of Veterans Affairs

Completed

Evaluation of Implementation of a National Point-of-Care Ultrasound Training Program

Heart Failure | Pneumonia | Cellulitis | Urinary Retention | Deep Venous Thrombosis | Hydronephrosis | Pleural Effusion | Abdominal Aortic Aneurysm | Acute Cholecystitis | Other Acute Illnesses Presenting to the Hospital | Peritoneal Free Fluid

United States
MedDay Pharmaceuticals SA

Completed

SERENDEM : MD1003 in Patients Suffering From Demyelinating Neuropathies, an Open Label Pilot Study

Charcot-Marie-Tooth Disease | Peripheral Neuropathy | Chronic Inflammatory Demyelinating Polyneuropathy | Charcot-Marie-Tooth Disease Type 1A | Charcot-Marie-Tooth Disease, Type 1B | Anti-MAG Neuropathy

France
Melaka Manipal Medical College

Completed

Knowledge, Attitude and Practice of Dental Students About COVID-19

Myalgia | Cough | Septic Shock | Bleeding | Fever | Acute Respiratory Distress Syndrome | Acute Lung Injury | Corona Virus Infection | Dyspnea

Malaysia
Manchester University NHS Foundation Trust

Completed

Effect of Implant Position on Magnetic Resonance Image Distortion

Neurofibromatosis Type 2

United Kingdom
M.D. Anderson Cancer Center
Merck Sharp & Dohme LLC

Terminated

Chemoradiation-Induced Nausea and Emesis: Quality of Life

Cervical Cancer | Gastric Cancer | Pancreatic Cancer | Vulvar Cancer | Endometrial Cancer | Anal Cancer

United States
National Cancer Institute (NCI)

Terminated

Amatuximab for High Mesothelin Cancers

Carcinoma, Non-Small-Cell Lung | Ovarian Neoplasms | Mesothelioma | Carcinoma, Pancreatic Ductal

United States
Peking University Third Hospital

Completed

MISA to NRDS：a Multicenter Study in China

Necrotizing Enterocolitis | Intraventricular Hemorrhage | Bronchopulmonary Dysplasia | Patent Ductus Arteriosus | Periventricular Leukomalacia

China
Oregon Health and Science University

Terminated

Sterol and Isoprenoid Disease Research Consortium: Smith-Lemli-Opitz Syndrome (STAIR-SLOS)

Smith-Lemli-Opitz Syndrome

United States
PTC Therapeutics
United States Department of Defense

Terminated

PTC299 for Treatment of Neurofibromatosis Type 2

Neurofibromatosis 2

United States
Centre Hospitalier Universitaire de Nice

Unknown

Cutaneous and Mucosal Manifestations of Neurofribromatosis Type 2 in Children Under 15

Neurofibromatosis 2 | Dermatology/Skin - Other

France
Ipsen

Completed

A Study With Tasquinimod Treating Patients With Hepatocellular, Ovarian, Renal Cell and Gastric Cancers

Metastatic Renal Cell Cancer | Advanced or Metastatic Hepatocellular Cancer | Advanced or Metastatic Ovarian Cancer | Advanced or Metastatic Gastric Carcinoma

Belgium, Canada, France, Spain, United Kingdom
National Cancer Institute (NCI)

Completed

AZD2171 in Treating Patients With Recurrent or Stage IV Melanoma

Intraocular Melanoma | Recurrent Melanoma | Stage IV Melanoma | Ciliary Body and Choroid Melanoma, Medium/Large Size | Ciliary Body and Choroid Melanoma, Small Size | Iris Melanoma | Extraocular Extension Melanoma | Acral Lentiginous Malignant Melanoma | Lentigo Maligna Malignant Melanoma | Superficial... and other conditions

Canada
Gynecologic Oncology Group
National Cancer Institute (NCI)

Terminated

Combination Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Stage III Ovarian Cancer

Ovarian Clear Cell Cystadenocarcinoma | Ovarian Endometrioid Adenocarcinoma | Ovarian Serous Cystadenocarcinoma | Primary Peritoneal Carcinoma | Malignant Ovarian Mixed Epithelial Tumor | Ovarian Mucinous Cystadenocarcinoma | Undifferentiated Ovarian Carcinoma | Stage III Ovarian Cancer

United States
Eunice Kennedy Shriver National Institute of Child...

Withdrawn

A Long-Term Study of Cholesterol Supplements for Smith-Lemli-Opitz Syndrome

Smith-Lemi-Opitz Syndrome
DePuy International

Terminated

A Multi-centre Study to Assess the Long-term Performance of the DePuy ASR™ System in Primary Hip Resurfacing Surgery

Osteoarthritis | Rheumatoid Arthritis | Avascular Necrosis | Post-traumatic Arthritis | Congenital Hip Dysplasia | Slipped Capital Femoral Epiphysis | Collagen Disorders | Nonunion of Femoral Fractures

Australia, Germany, United Kingdom
Assistance Publique - Hôpitaux de Paris

Completed

Efficacy and Safety Study of RAD001 in the Growth of the Vestibular Schwannoma(s) in Neurofibromatosis 2 (NF2) Patients (AFINF2)

Neurofibromatosis 2

France
DePuy International

Terminated

Multi-Centre Study to Assess the Long-term Performance of the DePuy ASR™ System in Resurfacing and Primary Total Hip Replacement

Osteoarthritis | Rheumatoid Arthritis | Avascular Necrosis | Post-traumatic Arthritis | Congenital Hip Dysplasia | Slipped Capital Femoral Epiphysis | Collagen Disorders | Nonunion of Femoral Fractures

Austria, Czech Republic, Finland, Germany, Norway, Portugal, Switzerland, United Kingdom
Massachusetts General Hospital
The Children's Tumor Foundation

Completed

Resiliency Training for Patients With Neurofibromatosis Via Videoconferencing With Skype

Neurofibromatosis | Neurofibromatosis 2 | Schwannomatosis | Neurofibromatosis I

United States
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI); Dana-Farber Cancer Institute

Completed

Sunitinib in Treating Patients With Metastatic, Locally Advanced, or Locally Recurrent Sarcomas

Sarcoma | Small Intestine Cancer | Ovarian Cancer | Endometrial Cancer | Desmoid Tumor | Adult Malignant Fibrous Histiocytoma of Bone

United States
Case Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Disease Management Program or Usual Care in Patients With Stage III or Stage IV Lung Cancer, Pancreatic Cancer, Ovarian Cancer, or Colorectal Cancer, and Their Caregivers

Colorectal Cancer | Pancreatic Cancer | Ovarian Cancer | Lung Cancer

United States
Eunice Kennedy Shriver National Institute of Child...

Completed

Prenatal Screening For Smith-Lemli-Opitz Syndrome

Pregnancy | Smith-Lemli-Opitz Syndrome

United States
UMC Utrecht
Dutch Health Care Insurance Board

Completed

Prevention of Glucocorticoid-Induced Osteoporosis in Rheumatic Diseases: Alendronate Versus Alfacalcidol.

Rheumatoid Arthritis | Polymyositis | Giant Cell Arteritis | Polymyalgia Rheumatica | Wegener's Granulomatosis

Netherlands
National Center for Research Resources (NCRR)
Oregon Health and Science University

Unknown

Phase II Study of Dietary Cholesterol for Smith-Lemli-Opitz Syndrome

Smith-Lemli-Opitz Syndrome

United States
Northwestern University
Seagen Inc.

Terminated

Brentuximab Vedotin + Rituximab as Frontline Therapy for Pts w/ CD30+ and/or EBV+ Lymphomas

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Diffuse Small Cleaved Cell Lymphoma | Recurrent Adult Immunoblastic Large Cell... and other conditions

United States
Princess Anna Mazowiecka Hospital, Warsaw, Poland
Medical University of Warsaw

Not yet recruiting

The High Initial Dose of Monitored Vitamin D Supplementation in Preterm Infants. (HIDVID)

Nephrolithiasis | Vitamin D Deficiency | Metabolic Bone Disease | Osteopenia of Prematurity | Late-Onset Neonatal Sepsis

Poland
Sun Yat-sen University

Not yet recruiting

First-line Maintenance Treatment With Fluzoparib Plus Bevacizumab in Advanced BRCA Wild Type Ovarian Cancer

Ovarian Cancer | Primary Peritoneal Cancer | High Grade Serous Adenocarcinoma of Ovary | High Grade Endometrioid Ovarian Cancer | Fallopian-tube Cancer

China
Australian and New Zealand Intensive Care Research...
The Alfred

Not yet recruiting

Trial of ECMO to De-Sedate, Extubate Early and Mobilise in Hypoxic Respiratory Failure (REDEEM)

Pneumonia | Extracorporeal Membrane Oxygenation | Mechanical Ventilation Complication | Hypoxemia | COVID-19 Respiratory Infection | Acute Respiratory Distress Syndrome Due to COVID-19

Australia, Germany
Sunnybrook Health Sciences Centre
Centre hospitalier de l'Université de Montréal (CHUM); Exactis Innovation; Princess...

Recruiting

Combination of Olaparib and Navitoclax in Women With HGSC and TNBC

Ovarian Cancer | Triple Negative Breast Cancer | High Grade Serous Carcinoma

Canada
University College, London
Barts & The London NHS Trust; Anticancer Fund, Belgium; JP Moulton Charitable...

Recruiting

Adaptive ChemoTherapy for Ovarian Cancer in Patients With Replased Platinum-sensitive High Grade Serous or High Grade Endometrioid Ovarian Cancer (ACTOv)

Ovarian Cancer | Fallopian Tube Cancer | Relapsed Ovarian Cancer | Peritoneal Cancer | High Grade Serous Carcinoma | Ovary Cancer | Endometrioid Carcinoma

United Kingdom

Clinical Trials on Urea Cycle Disorder

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Senegal

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations