Clinical Trials on Urethral Neoplasms

Total 107762 results

M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Gemcitabine, Paclitaxel, Doxorubicin in Metastatic or Unresectable Bladder Cancer With Decreased Kidney Function

Metastatic Transitional Cell Cancer of the Renal Pelvis and Ureter | Recurrent Bladder Cancer | Recurrent Transitional Cell Cancer of the Renal Pelvis and Ureter | Regional Transitional Cell Cancer of the Renal Pelvis and Ureter | Stage III Bladder Cancer | Stage IV Bladder Cancer | Transitional... and other conditions

United States
Mayo Clinic
National Cancer Institute (NCI)

Completed

Avelumab in Combination With Fluorouracil and Mitomycin or Cisplatin and Radiation Therapy in Treating Participants With Muscle-Invasive Bladder Cancer

Stage III Bladder Cancer AJCC v8 | Stage III Renal Pelvis Cancer AJCC v8 | Stage III Ureter Cancer AJCC v8 | Stage III Urethral Cancer AJCC v8 | Stage IIIA Bladder Cancer AJCC v8 | Stage IIIB Bladder Cancer AJCC v8 | Urethral Urothelial Carcinoma | Stage II Bladder Cancer AJCC v8 | Stage II Renal Pelvis... and other conditions

United States
Emory University
National Cancer Institute (NCI)

Recruiting

Immune Checkpoint Inhibitors With or Without Propranolol Hydrochloride In Patients With Urothelial Carcinoma

Metastatic Bladder Urothelial Carcinoma | Metastatic Renal Pelvis Urothelial Carcinoma | Metastatic Ureter Urothelial Carcinoma | Metastatic Urethral Urothelial Carcinoma | Metastatic Urothelial Carcinoma | Stage IV Bladder Cancer AJCC v8 | Stage IV Renal Pelvis Cancer AJCC v8 | Stage IV Ureter Cancer... and other conditions

United States
National Cancer Institute (NCI)

Completed

Gemcitabine Hydrochloride and Cisplatin With or Without Bevacizumab in Treating Patients With Advanced Urinary Tract Cancer

Metastatic Prostate Carcinoma | Metastatic Bladder Urothelial Carcinoma | Metastatic Renal Pelvis Urothelial Carcinoma | Metastatic Ureter Urothelial Carcinoma | Metastatic Urethral Urothelial Carcinoma | Metastatic Urothelial Carcinoma | Stage IV Bladder Urothelial Carcinoma AJCC v7 | Stage IV Renal... and other conditions

United States, Puerto Rico
Urotronic Inc.

Completed

ROBUST I Pilot Study, Re-Establishing Flow Via Drug Coated Balloon For The Treatment Of Urethral Stricture Disease (ROBUST)

Stricture Urethra

United States
National Cancer Institute (NCI)

Terminated

Sorafenib in Treating Patients With Regional or Metastatic Cancer of the Urothelium

Metastatic Transitional Cell Cancer of the Renal Pelvis and Ureter | Recurrent Bladder Cancer | Recurrent Transitional Cell Cancer of the Renal Pelvis and Ureter | Regional Transitional Cell Cancer of the Renal Pelvis and Ureter | Stage III Bladder Cancer | Stage IV Bladder Cancer | Transitional... and other conditions

United States
National Cancer Institute (NCI)

Active, not recruiting

Testing the Addition of the Anti-cancer Drug, Cabozantinib, to the Usual Immunotherapy Treatment, Avelumab, in Patients With Metastatic Urothelial Cancer, MAIN-CAV Study

Advanced Bladder Urothelial Carcinoma | Advanced Ureter Urothelial Carcinoma | Metastatic Bladder Urothelial Carcinoma | Metastatic Renal Pelvis Urothelial Carcinoma | Metastatic Ureter Urothelial Carcinoma | Metastatic Urethral Urothelial Carcinoma | Stage III Bladder Cancer AJCC v8 | Stage III... and other conditions

United States, Canada
National Cancer Institute (NCI)

Recruiting

Testing Combination Erdafitinib and Enfortumab Vedotin in Metastatic Bladder Cancer After Treatment With Chemotherapy and Immunotherapy

Metastatic Bladder Urothelial Carcinoma | Metastatic Renal Pelvis Urothelial Carcinoma | Metastatic Ureter Urothelial Carcinoma | Metastatic Urethral Urothelial Carcinoma | Metastatic Urothelial Carcinoma | Recurrent Bladder Urothelial Carcinoma | Recurrent Renal Pelvis Urothelial Carcinoma | Recurrent... and other conditions

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Erlotinib Hydrochloride in Treating Participants With Muscle Invasive or Recurrent Urothelial Cancer

Recurrent Bladder Urothelial Carcinoma | Recurrent Renal Pelvis Urothelial Carcinoma | Recurrent Ureter Urothelial Carcinoma | Recurrent Urethral Urothelial Carcinoma | Stage III Renal Pelvis Cancer AJCC v8 | Stage III Ureter Cancer AJCC v8 | Stage III Urethral Cancer AJCC v8 | Stage 0a Bladder Cancer... and other conditions

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Durvalumab and Tremelimumab in Treating Patients With Muscle-Invasive, High-Risk Urothelial Cancer That Cannot Be Treated With Cisplatin-Based Therapy Before Surgery

Hydronephrosis | Infiltrating Bladder Urothelial Carcinoma, Plasmacytoid Variant | Stage III Bladder Urothelial Carcinoma AJCC v6 and v7 | Stage III Renal Pelvis Cancer AJCC v7 | Stage III Ureter Cancer AJCC v7 | Stage III Urethral Cancer AJCC v7 | Stage IV Renal Pelvis Cancer AJCC v7 | Stage IV... and other conditions

United States
National Cancer Institute (NCI)

Recruiting

Comparing the New Anti-cancer Drug Eribulin With Chemotherapy Against the Usual Chemotherapy Alone in Metastatic Urothelial Cancer

Metastatic Bladder Urothelial Carcinoma | Metastatic Renal Pelvis Urothelial Carcinoma | Metastatic Ureter Urothelial Carcinoma | Metastatic Urethral Urothelial Carcinoma | Metastatic Urothelial Carcinoma | Stage IV Bladder Cancer AJCC v8 | Stage IV Renal Pelvis Cancer AJCC v8 | Stage IV Ureter Cancer... and other conditions

United States
National Cancer Institute (NCI)

Active, not recruiting

Atezolizumab With or Without Eribulin Mesylate in Treating Patients With Recurrent Locally Advanced or Metastatic Urothelial Cancer

Metastatic Bladder Urothelial Carcinoma | Metastatic Renal Pelvis Urothelial Carcinoma | Metastatic Ureter Urothelial Carcinoma | Metastatic Urethral Urothelial Carcinoma | Recurrent Bladder Urothelial Carcinoma | Recurrent Renal Pelvis Urothelial Carcinoma | Recurrent Ureter Urothelial Carcinoma and other conditions

United States
Marmara University

Completed

Is Urethral Catheter Necessary After Ureteroscopy and DJ Stent Placement?

Lower Urinary Tract Symptoms | Ureteral Catheterization | Flank Pain | Ureteroscopy | Complications; Urethral Catheter

Turkey
Fox Chase Cancer Center

Terminated

Gemcitabine Hydrochloride and Cisplatin Before Surgery in Treating Patients With Muscle Invasive Bladder Cancer

Stage III Bladder Cancer | Distal Urethral Cancer | Proximal Urethral Cancer | Squamous Cell Carcinoma of the Bladder | Urethral Cancer Associated With Invasive Bladder Cancer | Stage II Bladder Cancer

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Short-Term Low-Dose Interferon Alfa in Treating Patients With Cancer of the Urothelium

Bladder Cancer | Urethral Cancer

United States
Memorial Sloan Kettering Cancer Center

Completed

Combination Chemotherapy in Patients With Advanced Urinary Tract Cancer

Bladder Cancer | Urethral Cancer

United States
Southwest Oncology Group
National Cancer Institute (NCI)

Completed

S0121, Neoadjuvant Carboplatin, Paclitaxel, and Gemcitabine Followed by Cisplatin and Radiation Therapy in Treating Patients With Locally Advanced or Recurrent Carcinoma of the Urothelium

Bladder Cancer | Urethral Cancer

United States
M.D. Anderson Cancer Center
Millennium Pharmaceuticals, Inc.

Active, not recruiting

Bortezomib With Gemcitabine/Doxorubicin in Patients With Urothelial Cancer and Other Solid Tumors

Solid Tumor | Urethral Cancer

United States
National Cancer Institute (NCI)

Active, not recruiting

Atezolizumab and CYT107 in Treating Participants With Locally Advanced, Inoperable, or Metastatic Urothelial Carcinoma

Advanced Bladder Urothelial Carcinoma | Advanced Ureter Urothelial Carcinoma | Metastatic Bladder Urothelial Carcinoma | Metastatic Renal Pelvis Urothelial Carcinoma | Metastatic Ureter Urothelial Carcinoma | Metastatic Urethral Urothelial Carcinoma | Metastatic Urothelial Carcinoma | Recurrent Bladder... and other conditions

United States
Eastern Cooperative Oncology Group
National Cancer Institute (NCI)

Completed

Combination Chemotherapy in Treating Patients With Bladder Cancer

Bladder Cancer | Urethral Cancer

United States
M.D. Anderson Cancer Center

Recruiting

Nivolumab for the Treatment of Patients With Metastatic Urothelial Cancer With ARID1A Mutation and Stratify Response Based on CXCL13 Expression

Metastatic Bladder Urothelial Carcinoma | Metastatic Renal Pelvis Urothelial Carcinoma | Metastatic Ureter Urothelial Carcinoma | Metastatic Urethral Urothelial Carcinoma | Metastatic Urothelial Carcinoma | Recurrent Bladder Urothelial Carcinoma | Recurrent Renal Pelvis Urothelial Carcinoma | Recurrent... and other conditions

United States
National Cancer Institute (NCI)

Completed

Pazopanib in Treating Patients With Metastatic Urothelial Cancer

Recurrent Bladder Cancer | Recurrent Transitional Cell Cancer of the Renal Pelvis and Ureter | Stage IV Bladder Cancer | Transitional Cell Carcinoma of the Bladder | Distal Urethral Cancer | Proximal Urethral Cancer | Recurrent Urethral Cancer | Urethral Cancer Associated With Invasive Bladder Cancer

United States, China, Korea, Republic of
Fuda Cancer Hospital, Guangzhou

Completed

Irreversible Electroporation(IRE) For Unresectable Renal Pelvic and Ureteral Neoplasms (IRE)

Renal Pelvic and Ureteral Neoplasms

China
Tokushukai Medical Group

Unknown

A Clinical Study of the Living Renal Transplantation With Restored Kidneys Between Family Members

Renal Insufficiency | Kidney Stone | Ureteral Stricture | Kidney Neoplasm | Ureteral Tumor

Japan
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Fluorouracil, Leucovorin, Gemcitabine, and Cisplatin in Treating Patients With Metastatic or Unresectable Adenocarcinoma of the Urothelium or Urachal Remnant

Bladder Cancer | Urethral Cancer | Urachal Cancer

United States
Imperial College London
4D pharma plc

Active, not recruiting

MRx0518 in Patients With Solid Tumours Waiting Surgical Removal of the Tumour (MICROBIOME)

Melanoma | Breast Cancer | Head and Neck Cancer | Ovarian Cancer | Lung Cancer | Prostate Cancer | Bladder Cancer | Renal Cancer | Urethral Cancer | Uterine Cancer

United Kingdom
University Hospital, Ghent

Completed

Pre-operative Assessment by Sonourethrography Only in Anterior Urethral Strictures. (PASTIS)

Anterior Urethral Stricture, Male

Belgium
University Hospital, Ghent

Completed

Post-Operative Imaging After Urethroplasty With Peri-catheter Retrograde Urethrography Or Trial of Voiding With Voiding Cysto-urethrography (POIROT)

Urethral Stricture

Belgium
Oslo University Hospital
Helsinki University Central Hospital; Sahlgrenska University Hospital, Sweden; Region Örebro County

Completed

Scandinavian Urethroplasty Study (SUPS)

Urethral Stricture

Finland, Norway, Sweden
Universitaire Ziekenhuizen KU Leuven

Completed

Functional Outcome of Urethral Reconstructive Surgery

Urethral Stricture

Belgium
Betul Kartal
Istanbul Medipol University Hospital

Recruiting

Assessing the Knowledge and Self-confidence of Healthcare Workers to Perform Transurethral Catheterization: A Multicenter Survey

Catheter Complications | Catheter Related Complication | Urethral Catheterization | Urethral Catheterization Related Injury

Turkey
Urotronic Inc.

Withdrawn

Re-Establishing Flow Via Drug Coated Balloon for the Treatment of Urethral Stricture Disease - Registry Study (ROBUST IV)

Lower Urinary Tract Symptoms | Urethral Stricture | Urethral Stricture, Anterior | Anterior Urethral Stricture
National Cancer Institute (NCI)

Completed

TRC105 in Adults With Advanced/Metastatic Urothelial Carcinoma

Urothelial Carcinoma | Ureteral Neoplasms | Ureter Cancer | Cancer of the Ureter | Neoplasm, Ureteral

United States
University Hospital, Ghent

Withdrawn

Diagnosis of Urethral Stricture With Sono-urethrography vs Conventional Urethrography (SONO-URETHRA) (SONO-URETHRA)

Urethral Stricture Disease

Belgium
Lepu Medical Technology (Beijing) Co., Ltd.

Recruiting

Treatment of Urethral Stricture With Urethral Drug Ball

Urethral Stricture Less Than 2 cm

China
University Hospital Virgen de las Nieves
Instituto de Investigación Biosanitaria de Granada (ibs.Granada)

Recruiting

Urethral Stricture After Transurethral Resection of the Prostate/Bladder: a Prospective Study of Risk Factors (STRICT-TURP)

Fibrosis | Hormone Deficiency | Urethral Stricture, Male

Spain
Mansoura University

Recruiting

Overnight Bladder Drainage and Posterior Urethral Valve Sequelae

Posterior Urethral Valve

Egypt
Burnasyan Federal Medical Biophysical Center

Unknown

Effectiveness and Safety of Autologous Adipose-Derived Regenerative Cells for the Treatment of Urethral Strictures

Urethral Strictures in Males

Russian Federation
State University of New York - Upstate Medical...

Unknown

Liquid Buccal Mucosa Graft Urethroplasty (LBMG)

Urethral Stricture

United States
Services Hospital, Lahore
Armed Forces Institute of Urology, Rawalpindi

Completed

Role of Oral Steroids in Reducing Recurrence of Urethral Stricture After Direct Vision Internal Urethrotomy

Recurrence

Pakistan
Assistance Publique Hopitaux De Marseille

Recruiting

Safety and Potential Effect of Innovative Treatment by Adjuvant Injection of Stromal Vascular Fraction From Autologous Adipose Tissue of URethral Stenosis With Endoscopic Urethrotomy (SURF)

Urethral Stenosis

France
Sheba Medical Center

Unknown

Efficiency of Cold vs. Laser Internal Urethrotomy Treatment of Urethral Strictures (IU)

Urethral Strictures

Israel
Regenosca SA

Recruiting

Bioengineered Collagen Implant for Urethral Stricture Repair

Urethral Stricture

Malaysia
Ain Shams University

Completed

Holmium Laser Uretherotomy in Combination With Intralesional Steroids in Bulbar Uretheral Stricture

Urethral Stricture

Egypt
I.M. Sechenov First Moscow State Medical University

Unknown

Tissue-engineered Construct Based on Buccal Mucosa Cells and Matrix From Collagen and Polylactoglycolide Fibers

Urethral Stricture

Russian Federation
Pnn Medical DK

Completed

Memokath® 044TW Stent for Treatment of Urethral Stricture

Urethral Stricture

United States
Rahul Aggarwal
National Cancer Institute (NCI); U.S. Army Medical Research Acquisition Activity

Recruiting

64Cu-GRIP B in Patients With Advanced Malignancies

Prostate Cancer | Advanced Solid Tumor | Renal Cancer | Urethral Cancer | Solid Tumor, Adult | Metastatic Castration-resistant Prostate Cancer

United States
Coloplast A/S

Completed

Safety and Performance of a New Coating for Urinary Intermittent Catheters

Intermittent Urethral Catheterization

Denmark
University of Alabama at Birmingham
Astellas Pharma Inc

Completed

Medication Effects on Periurethral Sensation,Urethral Sphincter Activity and Pressure Flow Parameters

Urethral Sphincter Activity

United States
Groupe de Recherche Clinique en Neuro-Urologie

Completed

Urethral Sensory Profile: a New Technique to Evaluate Urethral Sensation Prospective Evaluation in Patients With or Without Neurological Disorders

Urethral Cyst

France

Clinical Trials on Urethral Neoplasms

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