Clinical Trials on VEXAS Syndome

Total 34307 results

Lawson Health Research Institute
Alexion Pharmaceuticals, Inc.

Active, not recruiting

Paroxysmal Nocturnal Hemoglobinuria in ESUS & ETUS

Transient Ischemic Attack | Paroxysmal Nocturnal Hemoglobinuria | Cerebral Vein Thrombosis | Embolic Stroke of Undetermined Source

Canada
National Cancer Institute (NCI)

Completed

Nivolumab in Treating Patients With HTLV-Associated T-Cell Leukemia/Lymphoma

Acute Adult T-Cell Leukemia/Lymphoma | Adult T-Cell Leukemia/Lymphoma | Chronic Adult T-Cell Leukemia/Lymphoma | HTLV-1 Infection | Lymphomatous Adult T-Cell Leukemia/Lymphoma | Smoldering Adult T-Cell Leukemia/Lymphoma

United States
Pharvaris Netherlands B.V.

Completed

Dose-ranging Study of Oral PHA-022121 for Acute Treatment of Angioedema Attacks in Patients With Hereditary Angioedema (RAPIDe-1)

Hereditary Angioedema | Hereditary Angioedema Type I | Hereditary Angioedema Type II | Hereditary Angioedema Types I and II | Hereditary Angioedema Attack | Hereditary Angioedema With C1 Esterase Inhibitor Deficiency | Hereditary Angioedema - Type 1 | Hereditary Angioedema - Type 2 | C1 Esterase Inhibitor... and other conditions

Bulgaria, United States, Spain, Israel, Germany, Canada, Czechia, France, Hungary, Italy, Netherlands, Poland, United Kingdom
University of California, San Francisco

Completed

Study of Clofarabine and Fludarabine Drug Exposure in Pediatric Bone Marrow Transplantation (HCT)

Sickle Cell Disease | Hemoglobinopathies | Thalassemia | Hematologic Malignancies | Immunodeficiencies | Fanconi's Anemia | Nonmalignant Diseases | Genetic Inborn Errors of Metabolism

United States
University of California, San Francisco
Thrasher Research Fund

Completed

Study of Fludarabine Drug Exposure in Pediatric Bone Marrow Transplantation (HCT)

Sickle Cell Disease | Hemoglobinopathies | Fanconi Anemia | Thalassemia | Hematologic Malignancies | Immunodeficiencies | Nonmalignant Diseases | Genetic Inborn Errors of Metabolism

United States
Shiphrah Biomedical Inc.
University of South Australia

Terminated

UniSA BackOff! Study: Adelaide PrenaBelt Trial

Pregnancy Complications | Fetal Growth Retardation | Sleep-Disordered Breathing | Infant, Very Low Birth Weight | Stillbirth | Infant, Small for Gestational Age | Fetal Hypoxia | Infant, Low Birth Weight

Australia
Chang Gung Memorial Hospital

Completed

High-flow Nasal Cannula Oxygen Therapy for Ischemic Stroke Patients With Dysphagia and Obstructive Sleep Apnea

Sleep Apnea, Obstructive | Deglutition Disorders | Cerebral Infarction

Taiwan
Pfizer

Terminated

Observational Familial Adenomatous Polyposis Registry Study In Patients Receiving Celecoxib Compared to Control Patients

Familial Adenomatous Polyposis (FAP)

United States, Spain, Canada, Denmark
Federico II University
University of Genova; University Hospital, Udine, Italy; University of Perugia...

Completed

High Dose Somatostatin Analogues in Neuroendocrine Tumors (HIDONET)

Gastrointestinal Neoplasms | Respiratory Tract Neoplasms | Pancreatic Neoplasms | Multiple Endocrine Neoplasia | Thymic Neoplasms

Italy
National Institute of Neurological Disorders and...

Completed

Endolymphatic Sac Tumors in a Population of Patients With Von Hippel-Lindau Disease:The Natural History and Pathobiology, and a Prospective Non-Randomized Clinical Trial of Hearing Preservation Surgery in Patients With Early Stage Endolymphatic Sac Tumors

Neoplasms | Kidney Neoplasms | Kidney Diseases | Retinal Diseases | Deafness

United States
NeurogesX

Completed

Tolerability of Three Local Anesthetic Formulations in Conjunction With NGX-4010 for the Treatment of Neuropathic Pain

HIV Infections | Pain | Diabetes Mellitus | Diabetic Neuropathies | Peripheral Nervous System Diseases | Neuralgia | Herpes Zoster | Polyneuropathies

United States
IRCCS San Raffaele
Università Vita-Salute San Raffaele

Recruiting

Mechanisms of Somatic Mutation and Tumor Initiation in Pre-malignant Kidney Tubule Cells (SoMuKT)

Carcinoma, Renal Cell | Von Hippel-Lindau Disease

Italy
National Cancer Institute (NCI)

Recruiting

Testing Obeticholic Acid for Familial Adenomatous Polyposis

Familial Adenomatous Polyposis | Colorectal Carcinoma | Attenuated Familial Adenomatous Polyposis | Duodenal Carcinoma

United States, Puerto Rico
National Institute of Diabetes and Digestive and...

Recruiting

Natural History Study of Parathyroid Disorders

Primary Hyperparathyroidism | Pseudohypoparathyroidism | Parathyroid Cancer | Inheritable Bone Diseases | Multiple Endocrine Neoplasia, Type 1

United States
Universitätsklinikum Hamburg-Eppendorf

Completed

Psychosocial Situation of Children With Rare Solid Abdominal Tumors and Their Families (PsyRareCare)

Neuroblastoma | Hepatoblastoma | Nephroblastoma

Germany
Pharvaris Netherlands B.V.

Active, not recruiting

Dose-ranging Study of Oral PHA-022121 for Prophylaxis Against Angioedema Attacks in Patients With Hereditary Angioedema Type I or Type II (HAE CHAPTER-1)

Hereditary Angioedema | Hereditary Angioedema Type I | Hereditary Angioedema Type II | Hereditary Angioedema Types I and II | Hereditary Angioedema Attack | Hereditary Angioedema With C1 Esterase Inhibitor Deficiency | Hereditary Angioedema - Type 1 | Hereditary Angioedema - Type 2 | C1 Esterase Inhibitor... and other conditions

United States, Poland, Germany, Austria, Bulgaria, Canada, Ireland, Italy, United Kingdom
Barbara Ann Karmanos Cancer Institute
National Cancer Institute (NCI)

Withdrawn

Home Sleep Apnea Machine in Evaluating Obstructive Sleep Apnea in Patients With Stage III-IV Head and Neck Cancer

Metastatic Head and Neck Squamous Cell Carcinoma | Locally Advanced Head and Neck Squamous Cell Carcinoma

United States
University of California, San Francisco

Completed

Study of Melphalan Drug Exposure in Pediatric Hematopoietic Stem Cell Transplant Patients

Sickle Cell Disease | Hemoglobinopathies | Thalassemia | Hematologic Malignancies | Immunodeficiencies | Fanconi's Anemia | Nonmalignant Diseases | Genetic Inborn Errors of Metabolism

United States
National Cancer Institute (NCI)

Completed

Celecoxib With or Without Eflornithine in Preventing Colorectal Cancer in Patients With Familial Adenomatous Polyposis

Colorectal Cancer | Familial Adenomatous Polyposis

United States
Copenhagen University Hospital, Hvidovre

Completed

Endoscopic Evaluation of Duodenal Polyposis in Patients With Familial Adenomatous Polyposis (FAP)

Duodenal Cancer | Duodenal Polyposis | Familial Adenomatous Polyposes

Denmark
Nationwide Children's Hospital
Ohio State University

Completed

Opioid Use, Storage, and Disposal Among Pediatric Patients After Surgery

Hernia | Sleep Disordered Breathing | Hypospadias | Tonsillitis | Hydrocele | Circumcision | Undescended Testicle

United States
Centre Hospitalier Universitaire Dijon

Completed

Research Into the Molecular Bases of a New Phenotype Combining Premature White Hair, Polycystic Kidney Disease, Aortic Dilation/Dissection and Lymphopenia (BCL-2)

New Phenotype (Combining Premature White Hair, Polycystic Kidney Disease, Aortic Dilation/Dissection and Lymphopenia)

France
Genzyme, a Sanofi Company

Completed

A Study To Assess ZD6474 (ZACTIMA™) Monotherapy In Locally Advanced or Metastatic Hereditary Medullary Thyroid Cancer

Thyroid Cancer

Italy, Spain, Romania, Netherlands, Canada, United States, Switzerland, Australia
michal roll

Unknown

Erythromycin Treatment for Readthrough of APC Gene Stop Codon Mutation in Familial Adenomatous Polyposis-minors' Adjusted Version

FAP-Familial Adenomatous Polyposis
Radboud University Medical Center
Dutch Cancer Society

Completed

Prevention of Progression of Duodenal Adenomas in Patients With Familial Adenomatous Polyposis (PreDuoFAP)

Familial Adenomatous Polyposis | Duodenal Neoplasms | Duodenal Polyps

Netherlands
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Amifostine in Treating Peripheral Neuropathy Caused by Paclitaxel in Patients With Solid Tumors

Breast Cancer | Ovarian Cancer | Lung Cancer | Prostate Cancer | Unspecified Adult Solid Tumor, Protocol Specific | Neurotoxicity

United States
Third Military Medical University

Not yet recruiting

Spatial Proteomics Profiles of Aldosterone-producing Adenoma and Unilateral Hyperplasia

Primary Aldosteronism Due to Aldosterone Producing Adenoma | Primary Aldosteronism Due to Adrenal Hyperplasia (Bilateral)

China
Karl Landsteiner University of Health Sciences
Universitätsklinikum Tulln

Recruiting

Register Study: Implementation of Pharyngeal Electrostimulation Therapy for the Treatment of Acute Neurogenic Dysphagia (R:IphEst)

Stroke | Dysphagia | Traumatic Brain Injury | Intubation Complication | Neurogenic Dysphagia | Long Covid-19 | Polyradiculitis

Austria
Mayo Clinic

Enrolling by invitation

Clinico-Pathologic-Genetic-Imaging Study of Neurodegenerative and Related Disorders (AND1)

Parkinson Disease | Semantic Dementia | Behavioral Variant of Frontotemporal Dementia | CBD | Apraxia of Speech | MSA - Multiple System Atrophy | FTD | PPA | PSP | PCA | LPA | Semantic Aphasia

United States
University Health Network, Toronto

Unknown

Diagnosing Frontotemporal Lobar Degeneration

Progressive Supranuclear Palsy | Semantic Dementia | Corticobasal Syndrome | Progressive Nonfluent Aphasia | Behavioral Variant Frontotemporal Dementia | Amyotrophic Lateral Sclerosis and/or Frontotemporal Dementia

Canada
Oulu University Hospital
University of Oulu; Academy of Finland; Roche Diagnostics; PerkinElmer, Inc.; Sigrid... and other collaborators

Recruiting

PEPPI Study: Identification of Women at Risk for Placental Dysfunction

Cardiovascular Diseases | Polycystic Ovary Syndrome | Iron-deficiency | Pre-Eclampsia | Intrauterine Growth Restriction | Hypertensive Disorder of Pregnancy | Proteinuria in Pregnancy

Finland
University Health Network, Toronto

Recruiting

Myeloproliferative Neoplasms (MPNs) Patient Registry

Neoplasms | Primary Myelofibrosis | Polycythemia Vera | Essential Thrombocythemia | Leukemia, Myelomonocytic, Chronic | Leukemia, Myelomonocytic, Juvenile | Myelodysplastic-Myeloproliferative Diseases | Mastocytosis | Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative | Chronic Eosinophilic Leukemia-not...

Canada
Fundación para la Lucha contra las Enfermedades...
Entelai

Completed

Artificial Intelligence-powered Virtual Assistant for Emergency Triage in Neurology (AIDEN)

Stroke | Delirium | Migraine | Meningitis | Subarachnoid Hemorrhage | Guillain-Barre Syndrome | Trigeminal Neuralgia | Status Epilepticus | Facial Palsy | Vertigo Benign Positional

Argentina
Chang Gung Memorial Hospital

Enrolling by invitation

A Study to Evaluate Accuracy and Validity of the Chang Gung ECG Abnormality Detection Software

Myocardial Infarction | Left Bundle-Branch Block | Atrial Flutter | Left Ventricular Hypertrophy | Long QT Syndrome | Sinus Bradycardia | Right Bundle-Branch Block | Sinus Tachycardia | Premature Atrial Complexes | Premature Ventricular Complexes

Taiwan
Universitaire Ziekenhuizen KU Leuven
Norwegian Institute of Public Health; KU Leuven; University Ghent; Sciensano

Completed

Evidence-based Laboratory Test Order Sets in Primary Care

Liver Diseases | Cardiovascular Diseases | Sexually Transmitted Diseases | Hypertension | Obesity | Diabetes Mellitus | Fatigue | Chronic Kidney Diseases | Thyroid Diseases | Rheumatoid Arthritis | Diarrhea | Anemia | Acute Coronary Syndrome | Gout | Lung Embolism | Medication Monitoring | General Check-up

Belgium
University of South Florida

Completed

Reliability and Validity of the MINI International Neuropsychiatric Interview for Children and Adolescents (MINI-KID)

Alcohol Dependence | Anxiety Disorders | ADHD | Mania | Major Depression | Conduct Disorder | Oppositional Defiant Disorder | Eating Disorders | Dysthymia | Pervasive Developmental Disorder | Drug Dependence | Suicidality | Psychotic Disorder | Tourettes Disorder

United States
Changi General Hospital
Singapore General Hospital

Recruiting

Outcome of Patients With Primary Aldosteronism (PA_Outcome)

Primary Aldosteronism | Hypokalemia | Chronic Renal Disease | Cardiovascular Morbidity | Mineralocorticoid Excess | Adrenalectomy; Status | Primary Aldosteronism Due to Aldosterone Producing Adenoma | Primary Aldosteronism Due to Adrenal Hyperplasia (Bilateral) | Mineralocorticoid Antagonists [Aldosterone...

Singapore
Children's Oncology Group
National Cancer Institute (NCI)

Active, not recruiting

Risk-Adapted Chemotherapy in Treating Younger Patients With Newly Diagnosed Standard-Risk Acute Lymphoblastic Leukemia or Localized B-Lineage Lymphoblastic Lymphoma

Acute Lymphoblastic Leukemia | Down Syndrome | Philadelphia Chromosome Positive | Childhood B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1 | Childhood B Acute Lymphoblastic Leukemia | Adult B Lymphoblastic Lymphoma | Ann Arbor Stage I B Lymphoblastic Lymphoma | Ann Arbor Stage... and other conditions

United States, Canada, Puerto Rico, Australia, New Zealand, Switzerland, Ireland
Case Comprehensive Cancer Center
National Cancer Institute (NCI)

Terminated

Etoposide, Filgrastim, and Plerixafor in Improving Stem Cell Mobilization in Treating Patients With Non-Hodgkin Lymphoma

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Diffuse Small Cleaved Cell Lymphoma and other conditions

United States
Case Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Methoxyamine and Fludarabine Phosphate in Treating Patients With Relapsed or Refractory Hematologic Malignancies

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Diffuse Small Cleaved Cell Lymphoma and other conditions

United States
Stanford University
National Cancer Institute (NCI)

Terminated

Ipilimumab and Local Radiation for Selected Solid Tumors

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Diffuse Small Cleaved Cell Lymphoma and other conditions

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Terminated

Monoclonal Antibody Therapy Before Stem Cell Transplant in Treating Patients With Relapsed or Refractory Lymphoid Malignancies

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Diffuse Small Cleaved Cell Lymphoma and other conditions

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Terminated

Lenalidomide With or Without Rituximab in Treating Patients With Progressive or Relapsed Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, Prolymphocytic Leukemia, or Non-Hodgkin Lymphoma Previously Treated With Donor Stem Cell Transplant

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Diffuse Small Cleaved Cell Lymphoma and other conditions

United States
National Cancer Institute (NCI)

Completed

Study of Akt Inhibitor MK2206 in Patients With Relapsed Lymphoma

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Diffuse Small Cleaved Cell Lymphoma | Recurrent Adult Immunoblastic... and other conditions

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute...

Completed

Low-Dose Total Body Irradiation and Donor Peripheral Blood Stem Cell Transplant Followed by Donor Lymphocyte Infusion in Treating Patients With Non-Hodgkin Lymphoma, Chronic Lymphocytic Leukemia, or Multiple Myeloma

Stage II Multiple Myeloma | Stage III Multiple Myeloma | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma and other conditions

United States, Germany, Italy
National Cancer Institute (NCI)

Completed

Veliparib, Bendamustine Hydrochloride, and Rituximab in Treating Patients With Relapsed or Refractory Lymphoma, Multiple Myeloma, or Solid Tumors

Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Diffuse Small Cleaved Cell Lymphoma | Recurrent Adult Lymphoblastic Lymphoma | Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma and other conditions

United States
National Cancer Institute (NCI)

Completed

Alisertib in Combination With Vorinostat in Treating Patients With Relapsed or Recurrent Hodgkin Lymphoma, B-Cell Non-Hodgkin Lymphoma, or Peripheral T-Cell Lymphoma

Recurrent Adult Burkitt Lymphoma | Recurrent Adult Lymphoblastic Lymphoma | Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma | Recurrent Grade 3 Follicular Lymphoma | Recurrent Mantle Cell Lymphoma | Recurrent Marginal Zone Lymphoma | Splenic Marginal Zone Lymphoma | Waldenstrom... and other conditions

United States
Rigshospitalet, Denmark

Not yet recruiting

Enhancing Lung Health in Kids With Structural Lung Damage and Malformations: Azithromycin (AZI) for Airway Infection Prevention (TRALULALA-AZI)

Bronchiectasis | Bronchopulmonary Dysplasia (BPD) | Tracheomalacia | Cystic Lung Disease | Vascular Ring | Chronic Atelectasis
University of Liverpool

Recruiting

Multi-morbidity Screening in People With Type 2 Diabetes and Pre Diabetes

Heart Failure | Obstructive Sleep Apnea | Type 2 Diabetes | Pre Diabetes | Non-Alcoholic Fatty Liver Disease

United Kingdom
Centre hospitalier de l'Université de Montréal...

Recruiting

Tolerance and Benefits of Mandibular Advanced Device for Snoring and Sleep Apnea in Oropharyngeal Cancer. (Ronco-Onco)

Snoring | Sleep Apnea | Oral Cancer | Oral Squamous Cell Carcinoma | Pharynx Cancer

Canada

Clinical Trials on VEXAS Syndome

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