Clinical Trials on VHL Gene Inactivation in Italy
Total 69 results
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Relay Therapeutics, Inc.Active, not recruitingCholangiocarcinoma | Intrahepatic Cholangiocarcinoma | FGFR2 Gene Mutation | FGFR2 Amplification | FGFR2 Gene Fusion/Rearrangement | FGFR2 Gene Translocation | FGFR2 Gene Activation | Other Solid Tumors, AdultUnited States, France, Italy, United Kingdom, Korea, Republic of, Spain, Taiwan, Sweden, Germany, Netherlands, Singapore, Australia, Hong Kong
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European Institute of OncologyActive, not recruitingLobular Breast Carcinoma | CDH1 Gene InactivationItaly
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Cervesi Hospital, Cattolica, ItalyRecruiting
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IRCCS Azienda Ospedaliero-Universitaria di BolognaRecruitingCancer Gene MutationItaly
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European Institute of OncologyIstituto Oncologico Veneto IRCCS; Ente Ospedaliero Ospedali Galliera; Istituto...Not yet recruitingDuctal Carcinoma in Situ | RAD51C Gene Mutation | RAD51D Gene Mutation | PALB2 Gene Mutation | Lobular Carcinoma in Situ | ATM Gene Mutation | CDH1 Gene Mutation | CHEK2 Gene Mutation | BRCA MutationItaly
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Istituto Clinico HumanitasCelgeneUnknownAcute Myeloid Leukemia | IDH2 Gene Mutation | IDH1 Gene MutationItaly
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Centre Leon BerardRecruitingCancer | Cancer Metastatic | ALK Fusion Protein Expression | FGFR2 Gene Translocation | FGFR3 Gene Translocation | NTRK Family Gene Mutation | Gene Fusion | ROS1 Gene Translocation | NTRK Gene Fusion Overexpression | ATIC-ALK Fusion Protein Expression | BCR-FGFR1 Fusion Protein Expression | COL1A1-PDGFB Fusion... and other conditionsFrance, Denmark, Netherlands, Austria, Germany, Italy, United Kingdom, Czechia, Poland, Slovenia, Spain
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University of Roma La SapienzaColuzzi Flaminia; Peruzzi Mariangela; Nocella Cristina; Loffredo Lorenzo; Marullo... and other collaboratorsCompletedEndothelial Dysfunction | Platelet Activation | Oxidative Stress InductionItaly
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Arog Pharmaceuticals, Inc.AvailableFLT3-ITD Mutation | FLT3/TKD Mutation | PDGFR-Alpha D842V | PDGFRA Gene AmplificationItaly
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San Raffaele UniversityUnita' di Gastroenterologia - Policlinico Universitario di Bari; Unita' di... and other collaboratorsRecruitingLynch Syndrome | MLH1 Gene Mutation | MSH2 Gene Mutation | MSH6 Gene Mutation | PMS2 Gene Mutation | Lynch Syndrome II | Small Bowel Adenocarcinoma | Lynch Syndrome IItaly
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University Medical Center NijmegenRecruitingOvarian Cancer | BRCA1 Gene Mutation | BRCA2 Gene Mutation | RAD51C Gene Mutation | RAD51D Gene Mutation | BRIP1 Gene MutationNetherlands, United States, Belgium, Norway, Poland, Italy, Australia, Mexico, Brazil, Sweden, Uruguay
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Cervesi Hospital, Cattolica, ItalyUnknown
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Fondazione Policlinico Universitario Agostino Gemelli...RecruitingGenetic Predisposition to Disease | Gene Rearrangement | Genome InstabilityItaly
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QED Therapeutics, Inc.Helsinn Healthcare SATerminatedFGFR2 Gene Mutation | Advanced CholangiocarcinomaUnited States, Belgium, Germany, Italy, Korea, Republic of, Russian Federation, Singapore, Spain, Taiwan, Thailand, United Kingdom
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Monaldi HospitalRecruitingHeart Failure | Lamin A/C Gene Mutation | LaminopathyItaly
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Blueprint Medicines CorporationCompletedSystemic Mast Cell Activation | KIT D816V MutationUnited States, France, United Kingdom, Italy, Germany, Belgium, Spain, Switzerland
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Università Politecnica delle MarcheNot yet recruitingLymphoma | Lung Neoplasms | Tuberculosis | EGF-R Positive Non-Small Cell Lung Cancer | Sarcoidosis | Mediastinal Lymphadenopathy | Hilar Lymphadenopathy | ROS1 Gene Mutation | PDL1 Gene Mutation | ALK TranslocationItaly
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Catholic University of the Sacred HeartUnknownRetinal Degeneration | Genetic Disease | Single-Gene Defects | Macular DystrophyItaly
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Fondazione Matilde Tettamanti Menotti De Marchi...RecruitingCLL | B-cell NHLItaly
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Maastricht University Medical CenterRecruitingPost-Infarction Heart Rupture | Gene PolymorphismItaly
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Orthofix s.r.l.CompletedJoint Diseases | Genu Varum | Genu Valgum | Knee Deformity | Ankle Deformity | Length Inequality, Leg | Discrepancy Length; Congenital | Deformity of LimbItaly
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ETOP IBCSG Partners FoundationAstraZenecaActive, not recruitingNSCLC Stage IV | EGFR Gene MutationSingapore, Sweden, Korea, Republic of, Spain, Switzerland, Netherlands, Italy, Poland
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Arog Pharmaceuticals, Inc.Centre Leon Berard; Fox Chase Cancer CenterUnknownGIST With D842V Mutated PDGFRA GeneUnited States, France, Spain, Italy, Germany, Norway, Poland
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QED Therapeutics, Inc.Helsinn Healthcare SATerminatedFGFR2 Gene Mutation | Advanced CholangiocarcinomaKorea, Republic of, United States, Belgium, Spain, Taiwan, China, United Kingdom, France, Canada, Germany, Thailand, Italy, Portugal, Australia, Puerto Rico
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Fondazione Policlinico Universitario Agostino Gemelli...RecruitingNSCLC Stage IV | ALK Gene Mutation | ALK Sensitizing MutationItaly
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Taiho Oncology, Inc.Active, not recruitingAdvanced Cholangiocarcinoma | FGFR2 Gene RearrangementsUnited States, Spain, United Kingdom, Australia, Taiwan, Italy, France, Korea, Republic of, Belgium, Japan, Thailand, Germany, Brazil, Peru, Portugal, Argentina, Hong Kong, Mexico, Netherlands, Poland
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Centro di Riferimento Oncologico - AvianoRecruitingBreast Neoplasms | Breast Diseases | Antineoplastic Agents | Aromatase Inhibitors | Neoplasms, Breast | Hormone Receptor Positive Breast Carcinoma | ESR1 Gene MutationItaly
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Fondazione I.R.C.C.S. Istituto Neurologico Carlo...University of Campania "Luigi Vanvitelli"; IRCCS National Neurological Institute...Active, not recruitingParkinson Disease | GBA Gene MutationItaly
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BayerRecruitingLocally Advanced or Metastatic Solid Tumor Harboring an NTRK Gene FusionUnited States, Austria, Denmark, Germany, Italy, Norway, Spain, United Kingdom, Brazil, Russian Federation, Switzerland, Taiwan, Canada, China, Australia, Greece, Belgium, Sweden, Korea, Republic of, France, Argentina, Finland, Ireland and more
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Istituto Ortopedico RizzoliRecruitingScoliosis Idiopathic | Genu Varum | Flat Feet | Hyperlordosis | Hyperkyphosis | Laxity of Ligament | Genu Valgus | Cavus Foot | Varus; Talipes | Valgus, Talipes | Angular Limb DeformityItaly
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Blueprint Medicines CorporationRecruitingIndolent Systemic Mastocytosis | Monoclonal Mast Cell Activation SyndromeUnited States, Spain, Australia, France, Netherlands, Switzerland, Norway, United Kingdom, Austria, Belgium, Germany, Italy, Portugal
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AstraZenecaMerck Sharp & Dohme LLC; Myriad Genetic Laboratories, Inc.Active, not recruitingBreast Cancer Metastatic | BRCA 1 Gene Mutation | BRCA 2 Gene MutationItaly, Spain, United States, Czechia, Romania, France, Korea, Republic of, United Kingdom, Hungary, Japan, Peru, Poland, Russian Federation, Turkey, China, Taiwan, Bulgaria, Switzerland, Mexico
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PfizerMedivation, Inc.CompletedBreast Neoplasms | BRCA 1 Gene Mutation | BRCA 2 Gene MutationKorea, Republic of, United States, Australia, Spain, Belgium, France, Ireland, Taiwan, Poland, Germany, Israel, Brazil, United Kingdom, Italy, Russian Federation, Ukraine
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Consorzio OncotechActive, not recruitingMetastatic Breast Cancer | Triple Negative Breast Cancer | PD-L1 Gene MutationItaly
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Istituto Scientifico Romagnolo per lo Studio e...TerminatedEstrogen Receptor Positive Breast Cancer | Androgen Receptor Gene Overexpression | Progesterone Receptor Positive Tumor | Metastatic Breastcancer | Estrogen Receptor Negative Neoplasm | Progesterone Receptor Negative NeoplasmItaly
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Gruppo Italiano Malattie EMatologiche dell'AdultoNot yet recruitingChronic Lymphocytic Leukemia | Small Lymphocytic Lymphoma | CLL-like MBL | Varicella-zoster Virus ReactivationItaly
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Taiho Oncology, Inc.RecruitingAdvanced Cholangiocarcinoma | FGFR2 Fusions | Gene RearrangementUnited States, Korea, Republic of, Spain, Japan, Portugal, Italy, China, Argentina, Brazil, Poland, Australia
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IRCCS San RaffaeleRecruitingClear Cell Renal Cell Carcinoma | VHL SyndromeItaly
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Centro di Riferimento Oncologico - AvianoRecruitingNon Small Cell Lung Cancer Metastatic | ALK Gene MutationItaly
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Rhythm Pharmaceuticals, Inc.CompletedPro-opiomelanocortin (POMC), Proprotein Convertase Subtilisin/Kexin Type 1 (PCSK1) and Leptin Receptor (LepR) Gene MutationsUnited States, Israel, Canada, Germany, Greece, Italy, Portugal
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PfizerTerminatedLocally Advanced or Metastatic Solid Tumors | Genes, BRCA 1United States, Belgium, Spain, Denmark, Japan, France, Italy, Netherlands, United Kingdom
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Swedish Orphan BiovitrumCompletedArthritis, Juvenile | Lymphohistiocytosis, Hemophagocytic | Macrophage Activation Syndrome | Adult Onset Still DiseaseUnited States, Spain, United Kingdom, France, Italy
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Swedish Orphan BiovitrumRecruitingStill's Disease, Adult-Onset | Macrophage Activation Syndrome | Stills Disease, Juvenile-OnsetUnited States, Canada, France, Germany, Italy, Netherlands, Spain
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Blueprint Medicines CorporationActive, not recruitingIndolent Systemic MastocytosisCanada, United States, Spain, United Kingdom, Germany, Belgium, Switzerland, Italy, Netherlands, Denmark, France, Norway, Sweden
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Basilea PharmaceuticaCompletedIntrahepatic Cholangiocarcinoma | Combined Hepatocellular and CholangiocarcinomaCanada, United States, Spain, Belgium, Italy, Korea, Republic of, Germany, Switzerland, France, United Kingdom, Ireland
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Centre Leon BerardMinistry of Health, FranceTerminatedHistologically Confirmed Medulloblastoma | Activation of the Sonic Hedgehog (SHH) PathwayFrance, Italy, Switzerland, United Kingdom
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Kura Oncology, Inc.Active, not recruitingHNSCC | HRAS Gene MutationUnited States, Belgium, Spain, United Kingdom, Taiwan, Denmark, Korea, Republic of, Netherlands, Thailand, Germany, Malaysia, Austria, Italy, Greece, Australia, Norway
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Tesaro, Inc.European Organisation for Research and Treatment of Cancer - EORTC; Breast... and other collaboratorsTerminatedOvarian Neoplasms | BRCA1 Gene Mutation | BRCA2 Gene Mutation | Neoplasms, Breast | Human Epidermal Growth Factor 2 Negative Carcinoma of Breast | Carcinoma of BreastUnited States, Spain, Belgium, Israel, United Kingdom, Italy, Poland, Canada, Hungary, Netherlands, France, Portugal, Greece, Iceland
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PfizerTerminatedDilated Cardiomyopathy | Lamin A/C Gene MutationUnited States, Spain, Canada, Belgium, Italy, Argentina, Mexico, Netherlands, Norway, United Kingdom
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Cogent Biosciences, Inc.RecruitingMastocytosis | Mastocytosis, Systemic | SSM | Mastocytosis, IndolentUnited States, Italy, Canada, Australia, Spain, Switzerland, Norway, United Kingdom, Belgium, Poland, Netherlands, Germany, France, Czechia, Greece, Ireland