Clinical Trials on Vaccines, Adverse Effects in South Africa

Total 187 results

Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating a 13-valent Pneumococcal Conjugate Vaccine in Elderly Subjects

Vaccines, Pneumococcal Conjugate Vaccine

South Africa
Companion Dx Reference Lab, LLC

Unknown

Utility of PharmacoGenomics for Reducing Adverse Drug Effects (UPGRADE)

Genetics of Drug Metabolism

United States
PATH
Bill and Melinda Gates Foundation; Children's Hospital Medical Center, Cincinnati and other collaborators

Completed

Mixed Schedule Study of Live Oral Rotavirus Vaccines and Trivalent P2-VP8 Subunit Rotavirus Vaccine

Rotavirus Vaccine

South Africa
University of Cape Town
Medical Research Council, South Africa

Completed

A Trial Of Intravenous N-Acetylcysteine In The Management Of Antituberculous Drug-Induced Hepatitis (NAC in TB DIH)

Drug-Induced Liver Injury

South Africa
PATH

Completed

Phase I/II Descending Age Study of P2VP8 Subunit Parenteral Rotavirus Vaccine in Healthy Toddlers and Infants

Evaluation of a Rotavirus Vaccine

South Africa
Boston Medical Center
Boston University; National Institute of Allergy and Infectious Diseases (NIAID) and other collaborators

Completed

The Impact of Alcohol Consumption on Tuberculosis Treatment Outcomes

Tuberculosis | Alcohol Consumption | Treatment Adverse Effect

South Africa
HIV Vaccine Trials Network
South Africa AIDS Vaccine Initiative

Completed

Safety of and Immune Response to a DNA HIV Vaccine Boosted With a Modified Vaccinia HIV Vaccine and Protein HIV Vaccine in Healthy Adults

HIV Seronegativity | HIV Preventive Vaccine

South Africa
Murdoch Childrens Research Institute

Recruiting

Minimising Adverse Drug Reactions and Verifying Economic Legitimacy in Children (MARVEL-PIC) (MARVEL-PIC)

Neoplasms | Bone Marrow Transplantation

Australia
Brigham and Women's Hospital
University of Chicago; University of Wisconsin, Madison; University of California... and other collaborators

Completed

Multi-Center Medication Reconciliation Quality Improvement Study (MARQUIS)

Medication Administered in Error | Adverse Drug Events

United States
GlaxoSmithKline

Completed

Immunogenicity and Safety of a Candidate Tuberculosis (TB) Vaccine Given to Healthy Adults in a TB-endemic Region

Tuberculosis (TB) | Tuberculosis Vaccines

South Africa
Faculty of Medicine

Completed

Uterotonic Efficacy of Oxytocin 2.5 Versus 10 Units During Caesarean Section at Mulago Hospital

Uterine Hemorrhage | Adverse Effect of Oxytocic Drugs | Inappropriate Dose of Drug Administered

Uganda
University of Cape Town
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Recruiting

B. Infantis Supplementation to Improve Immunity in Infants Exposed to HIV (BifIID)

Vaccine Reaction | Hiv | Microbial Colonization | Infant Development

South Africa
Pfizer

Completed

13vPnC Multidose Vial Safety, Tolerability and Immunogenicity Study in Healthy Infants.

Pneumococcal Vaccines

Gambia
Shabir Madhi

Not yet recruiting

Pertussis Vaccination Among HIV-infected and HIV-uninfected Pregnant Women

dTap Vaccine

South Africa
Pharmaceutical Project Solutions, Inc.

Completed

Topical Anesthetic for Procedures Through the Nose

Drug Reaction to Analgesic Nos

United States
Abbott Medical Devices

Completed

Safety and Efficacy of the Accent Magnetic Resonance Imaging™ (MRI) Pacemaker and Tendril MRI™ Lead

Adverse Effect of MRI on an Implanted Pacemaker Lead | Adverse Effect of MRI on an Implanted Pacemaker

United States, Netherlands, Australia, Belgium, Finland
Renaissance RX
Syntactx

Unknown

Diagnosing Adverse Drug Reactions Registry (DART)

Genetics of Drug Metabolism

United States
GLYCAR SA (Pty) Ltd

Recruiting

Post Market Observational Retrospective Study of Glycar Bovine Pericardial Patch (CIP-003)

Cardiac Anomaly | Cardiac Defect | Pericardial Defect

South Africa
GlaxoSmithKline
Aeras

Completed

Study to Evaluate the Efficacy of GlaxoSmithKline (GSK) Biologicals' Candidate Tuberculosis (TB) Vaccine in Adults

Tuberculosis | Tuberculosis Vaccines

South Africa, Kenya, Zambia
Flinders University
Flinders Medical Centre; Lyell McEwin Hospital

Recruiting

Assessment of Myocardial Injury in Patients Treated With Immune Checkpoint Inhibitors (MIICI)

Myocardial Injury | Myocarditis | Cardiotoxicity | Immune Checkpoint Inhibitors

Australia
Sanofi Pasteur, a Sanofi Company

Completed

Study to Evaluate the Immune Response After Booster Vaccination With Tdap-IPV Vaccine (Against Tetanus, Diphtheria, Pertussis and Poliomyelitis) in Children Who Received Different Pertussis Primary Vaccine Regimens in Republic of South Africa

Pertussis Immunisation | Diphtheria Immunisation | Tetanus Immunisation | Poliomyelitis Vaccine

South Africa
Duke University
University of South Carolina

Completed

Increase Vaccine Uptake in Adolescent in Rural South (INVEST)

Vaccine Hesitancy

United States
Pfizer

Completed

A Clinical Trial to Study the Safety, Tolerance and Immunogenic Response to MCV4, Tdap and Bivalent rLP2086 Vaccine When Given at the Same Time to Children Between the Ages of 10 Through 12 Years of Age

Vaccines | Meningococcal Vaccines

United States
The University of New South Wales

Completed

The Effect of Timing of Transcranial Direct Current Stimulation (tDCS) for Enhancing Learning During Cognitive Training

Effects on Learning

Australia
Vaxcyte, Inc.

Completed

Safety, Tolerability, and Immunogenicity Study of a 24-Valent Pneumococcal Conjugate Vaccine (VAX-24) in Older Adults

Pneumococcal Vaccines

United States
Vaxcyte, Inc.

Completed

Safety, Tolerability, and Immunogenicity Study of a 24-Valent Pneumococcal Conjugate Vaccine (VAX-24) in Adults

Pneumococcal Vaccines

United States
Kevin Winthrop
Medical University of South Carolina; Mayo Clinic; University of Washington; National... and other collaborators

Not yet recruiting

Prevention of Ototoxicity in NTM Patients Treated With IV Amikacin

Ototoxicity, Drug-Induced

United States
IDeA States Pediatric Clinical Trials Network
National Institutes of Health (NIH); University of Nebraska; University of Montana

Active, not recruiting

Improving Pediatric COVID-19 Vaccine Uptake Using an mHealth Tool (MoVeUP)

Telemedicine | Pediatric ALL | Vaccine Hesitancy | COVID-19 Vaccines

United States
University of Nebraska Lincoln
Centers for Disease Control and Prevention; Bennington College

Completed

The Impact of an Adapted Version of the Strengthening Families Program on IPV Among Caregivers and ACEs Among Children

Domestic Violence | Adverse Childhood Experiences

United States
Universitas Sriwijaya

Active, not recruiting

Efficacy of Extra Virgin Olive Oil (EVOO) Supplementation on Hand-Foot Syndrome Incidence in Patients With Capecitabine (EVOO)

Capecitabine | Hand and Foot Syndrome | Hand and Foot Skin Reaction

Indonesia
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study to Evaluate a 13-valent Pneumococcal Conjugate Vaccine in Infants.

Vaccines, Pneumococcal

Spain
Pfizer

Completed

A Clinical Trial to Study the Safety, Tolerance and Immunogenic Response to Gardasil and Bivalent rLP2086 Vaccine When Given at the Same Time to Children Between the Ages of 11 and 17

Vaccines | Meningococcal Vaccines

United States
Sound Pharmaceuticals, Incorporated
Medical University of South Carolina; Cystic Fibrosis Foundation

Enrolling by invitation

SPI-1005 for Prevention and Treatment of Tobramycin Induced Ototoxicity

Ototoxicity

United States
Sheffield Teaching Hospitals NHS Foundation Trust
University of Sheffield

Completed

Effects of Serotonin Excess on Bone in Carcinoid Syndrome

Carcinoid Syndrome

United Kingdom
Pfizer

Completed

Study Comparing 13-valent Pneumococcal Conjugate Vaccine With 7-valent Pneumococcal Conjugate Vaccine

Vaccines, Pneumococcal

United States
Vaxcyte, Inc.

Active, not recruiting

Safety, Tolerability, and Immunogenicity Study of a 31-Valent Pneumococcal Conjugate Vaccine (VAX-31) in Adults

Pneumococcal Vaccines

United States
Pfizer

Completed

A Trial to Describe the Safety and Immunogenicity of MenABCWY When Administered on 2 Schedules

Meningococcal Vaccine

United States
Avera McKennan Hospital & University Health Center

Terminated

Use of Metformin to Reduce Cardiac Toxicity in Breast Cancer

Breast Cancer | Breast Tumors

United States
Providence Therapeutics Holdings Inc.

Completed

PTX-COVID19-B, an mRNA Humoral Vaccine, Intended for Prevention of COVID-19 in a General Population. This Study is Designed to Demonstrate the Safety, Tolerability, and Immunogenicity of PTX-COVID19-B in Comparison to the Pfizer-BioNTech COVID-19 Vaccine.

Covid19 Vaccine

Canada, South Africa
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating 13-valent Pneumococcal Conjugate Vaccine In Healthy Infants

Vaccines, Pneumococcal

United States
EyeGene Inc.
Novotech (Australia) Pty Limited

Active, not recruiting

Study to Assess the Safety, Tolerability and Explore the Immunogenicity of EG-COVID and EG-COVARo in Healthy Adult Volunteers

COVID-19 Vaccine

Australia
Lykos Therapeutics

Completed

Psychological Effects of Methylenedioxymethamphetamine (MDMA) When Administered to Healthy Volunteers (MT-1)

Psychological Effects of Study Drug

United States
Masaryk University
University of Kiel; University of Giessen; F.D. Roosevelt Teaching Hospital with... and other collaborators

Unknown

Oral Side Effects of COVID-19 Vaccine

Covid19 | Vaccine Adverse Reaction | Oral Manifestations

Czechia, Germany, Slovakia
University of South Carolina

Completed

Sistas Inspiring Sistas Through Activity and Support (SISTAS)

Prevention Harmful Effects

United States
Pfizer

Completed

MenABCWY Noninferiority Study in Healthy Participants ≥10 to <26 Years of Age

Meningococcal Vaccine

United States, Denmark, Hungary, Czechia, Poland
Royal Prince Alfred Hospital, Sydney, Australia

Completed

Cardiotoxicity of Adjuvant Trastuzumab (CATS)

Heart Failure | Breast Neoplasms

Australia
South Australian Health and Medical Research Institute
University of Sydney; Telethon Kids Institute; Flinders University; Royal Adelaide... and other collaborators

Recruiting

Antibiotics and Vaccine Immune Responses Study (AVIRS)

Vaccine Response Impaired

Australia
Case Comprehensive Cancer Center

Terminated

Older Patients With Newly Diagnosed Breast Cancer or Colon Cancer

Breast Cancer | Colorectal Cancer | Cognitive/Functional Effects | Psychosocial Effects of Cancer and Its Treatment

United States
Pfizer

Completed

A Trial to Describe the Immunogenicity and Safety of 2 Doses of Bivalent rLP2086 (Trumenba) and a Pentavalent Meningococcal Vaccine in Healthy Subjects >=10 to <26 Years of Age.

Meningococcal Vaccine

United States, Finland, Czechia, Poland
Ipsen

Completed

An Efficacy and Safety Study of Somatuline Depot (Lanreotide) Injection to Treat Carcinoid Syndrome (ELECT)

Carcinoid Syndrome

United States, Turkey, Brazil, India, Ukraine, South Africa, Czechia, Latvia, Poland, Russian Federation, Serbia

Clinical Trials on Vaccines, Adverse Effects in South Africa

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