Clinical Trials on Valve Disease, Heart in United Kingdom

Total 148043 results

Abbott Medical Devices

Completed

St. Jude Medical Percutaneous Mitral Valve Repair Study (SJM PMVr)

Mitral Valve Prolapse

United Kingdom
Edwards Lifesciences

Completed

EDWARDS INTUITY Valve System FOUNDATION Study (FOUNDATION)

Aortic Stenosis | Aortic Valve Disease | Rapid Deployment Valves

Spain, United Kingdom, Austria, Netherlands, Italy, France, Germany, Denmark, Switzerland
Brighton and Sussex University Hospitals NHS Trust
Terumo Medical Corporation; University of Melbourne

Completed

Neurocognitive Assessment in TAVI (NEAT TAVI)

Aortic Valve Disease

United Kingdom
Oxford University Hospitals NHS Trust
Edwards Lifesciences

Recruiting

Early Discharge After Mitral and Tricuspid Edge-to-edge Repair: an Assessment of Feasibility and Safety (EARLY-Edge)

Heart Failure | Mitral Regurgitation | Tricuspid Regurgitation | Mitral Repair

United Kingdom
Edwards Lifesciences

Completed

CE Mark Study for the Harpoon Medical Device (TRACER)

Mitral Valve Insufficiency | Mitral Valve Prolapse | Mitral Valve Regurgitation

Italy, United Kingdom
Papworth Hospital NHS Foundation Trust

Recruiting

Quality of Life After Cardiac Surgery (QUACS)

Aortic Valve Stenosis | Coronary Artery Bypass Graft | Mitral Valve Disease | Tricuspid Valve Disease | Aorta Disease

United Kingdom
Guy's and St Thomas' NHS Foundation Trust
King's College Hospital NHS Trust; Manchester Metropolitan University

Completed

Percutaneous Mitral Valve Intervention: Predicting Improvements in Left Ventricular Performance (PMVI-PiP)

Mitral Regurgitation | Mitral Valve Insufficiency

United Kingdom
University of East Anglia
Clinical Research and Trials Unit (Norfolk & Norwich University Hospital,...

Recruiting

The Role of SGLT2i in Management of Moderate AS

Moderate Aortic Valve Stenosis

United Kingdom
University Hospitals, Leicester

Recruiting

The BRAVE Study- The Identification of Genetic Variants Associated With Bicuspid Aortic Valve Using a Combination of Case-control and Family-based Approaches. (BRAVE)

Cardiovascular Diseases

United Kingdom
Imperial College London
McGill University; Erasmus Medical Center; Academisch Medisch Centrum - Universiteit... and other collaborators

Completed

Protocoled Quantitative Assessment of Aortic Regurgitation Using Videodensitometry in a Multicontinental Trial in Rotterdam, Montreal, Yamaguchi, Segeberg, Amsterdam. (ASSESS-REGURGE)

Aortic Valve Insufficiency | Aortic Valve Regurgitation

Netherlands, Canada, Germany, Japan, United Kingdom
Imperial College London

Unknown

Determination of the Acute Effects of Aortic Stenosis on Coronary Artery Haemodynamics

Aortic Valve Stenosis

United Kingdom
University Hospital Birmingham NHS Foundation Trust
British Heart Foundation

Completed

The Role of Myocardial Fibrosis in Degenerative Mitral Regurgitation

Mitral Regurgitation | Mitral Valve Regurgitation

United Kingdom
James Cook University Hospital
Medela AG

Unknown

Enhanced Recovery After Cardiac Surgery (ERAS)

Coronary Artery Disease | Aortic Valve Disease | Cardiac Surgery | Mitral Valve Disease | Tricuspid Valve Disease | Aortic Root Dilatation

United Kingdom
University of Hull

Recruiting

PREhabilitation in Patients Awaiting Acute Inpatient Cardiac SurgEry ((PREP-ACE))

Coronary Artery Disease | Aortic Valve Disease | Endocarditis | Cardiac Disease | Valve Heart Disease

United Kingdom
University of Edinburgh
British Heart Foundation; Life Molecular Imaging SA

Completed

18F-GP1 PET-CT to Detect Bioprosthetic Aortic Valve Thrombosis

Aortic Valve Disease | Thrombosis Cardiac

United Kingdom
University of Oxford
British Heart Foundation

Active, not recruiting

Oxford - Fibrates in Aortic Stenosis (OxFAST)

Aortic Valve Stenosis

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust

Completed

Does Cardiac REhabilitation Improve Functional, Independence, Frailty and Emotional outCOmes Following Trans Catheter Aortic ValvE Replacement? (RECOVER-TAVR)

Aortic Stenosis

United Kingdom
University of Edinburgh

Recruiting

The Scottish Aortic Stenosis LongiTudinal Imaging and biomarkeR (SALTIRE) Programme (SALTIRE)

Aortic Stenosis

United Kingdom
University College, London
Barts & The London NHS Trust

Recruiting

Mechanisms of Excess Risk in Aortic Stenosis (MASTER)

Heart Failure | Aortic Stenosis | Non-Sustained VT

United Kingdom
London North West Healthcare NHS Trust

Completed

Clinical Value of Stress Echocardiography in Moderate Aortic Stenosis

Aortic Valve Stenosis

United Kingdom
Metanoic Health Ltd.
Abbott Medical Devices

Completed

Incidence of Significant Mitral Regurgitation in Acute Heart Failure Patients (MRAHF)

Mitral Regurgitation | Acute Heart Failure

United Kingdom
St. George's Hospital, London

Completed

Indexed Aortic Area in Bicuspid Aortic Valve Aortopathy

Thoracic Aortic Aneurysm | Bicuspid Cardiac Valve

United Kingdom
University Hospitals Coventry and Warwickshire...
Coventry University

Completed

Early Initiation of Post Sternotomy CArdiac Rehabilitation (SCAR)

Coronary Artery Disease | Aortic Valve Disease | Mitral Valve Disease

United Kingdom
East and North Hertfordshire NHS Trust
Royal Brompton & Harefield NHS Foundation Trust

Not yet recruiting

Avr Thrombosis OutcoMe Study (ATOM)

Aortic Stenosis

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust

Withdrawn

A Comparison of Advanced Imaging Techniques in Aortic Stenosis (AIm-AS)

Aortic Stenosis

United Kingdom
Guy's and St Thomas' NHS Foundation Trust
King's College London

Not yet recruiting

Outcome Prediction in Patients With Aortic Stenosis After TAVI (PREDICT-TAVI)

Aortic Stenosis, Severe

United Kingdom
St George's, University of London
King's College Hospital NHS Trust; Guy's and St Thomas' NHS Foundation Trust

Completed

Exercise Training in Hypertrophic Cardiomyopathy: (SAFE-HCM) (SAFE-HCM)

Hypertrophic Cardiomyopathy

United Kingdom
Edwards Lifesciences

Terminated

A Clinical Study of the CardiAQ™ TMVI System (Transapical DS)

Cardiovascular Disease | Heart Disease | Heart Valve Disease | Mitral Insufficiency

Netherlands, United Kingdom, Denmark, France
University College, London
British Heart Foundation

Unknown

Trimetazidine Therapy in Hypertrophic Cardiomyopathy

Hypertrophic Cardiomyopathy

United Kingdom
Barts & The London NHS Trust

Active, not recruiting

Pacemaker Therapy for Drug-refractory Symptoms in Mid-cavity Hypertrophic Cardiomyopathy

Cardiomyopathy, Hypertrophic

United Kingdom
University Hospital Southampton NHS Foundation...

Completed

Reactive Oxygen Species Following Aortic Valve Replacement (ROS)

Aortic Stenosis

United Kingdom
Barts & The London NHS Trust
Barts Cardiovascular CTU (Queen Mary University of London)

Not yet recruiting

Non-Invasive Radiation Ablation in Patients With Hypertrophic CardioMyopathy: NIRA-HOCM (NIRA-HOCM)

Hypertrophic Cardiomyopathy

United Kingdom
University of Edinburgh
Sir Jules Thorn Charitable Trust

Active, not recruiting

Early Valve Replacement Guided by Biomarkers of LV Decompensation in Asymptomatic Patients With Severe AS (EVoLVeD)

Aortic Valve Stenosis | Hypertrophy, Left Ventricular

United Kingdom
Newcastle-upon-Tyne Hospitals NHS Trust
Assistance Publique - Hôpitaux de Paris; Azienda Ospedaliero-Universitaria... and other collaborators

Completed

Lifestyle and Pharmacological Interventions in Hypertrophic Cardiomyopathy (SILICOFCM)

Hypertrophic Cardiomyopathy

United Kingdom
Abbott Medical Devices

Completed

First in Human Experience of the St. Jude Medical TAVI Valve and Delivery System (SJM TAVI FIH)

Symptomatic Aortic Stenosis

United Kingdom
University College, London

Completed

Regression of Myocardial Fibrosis After Aortic Valve Replacement (RELIEF-AS)

Aortic Stenosis

United Kingdom
University College, London
Inherited Cardiac Diseases Unit, The Heart Hospital, London

Unknown

Morbidity and Mortality in Patients With Hypertrophic Cardiomyopathy: a CALIBER Study (HCM)

Hypertrophic Cardiomyopathy

United Kingdom
Medstar Health Research Institute
Food and Drug Administration (FDA)

Completed

Transcatheter Aortic Valve Intervention-Live Transmission (VERITAS)

Aortic Valve Disorder

Italy, Switzerland, United States, Germany, Canada, United Kingdom
Medtronic Bakken Research Center

Completed

Engager Direct Aortic Clinical Study

Aortic Valve Stenosis

United Kingdom, Germany, Czechia
University of East Anglia
Norfolk and Norwich University Hospitals NHS Foundation Trust; British Medical...

Unknown

Nitrite in Hypertrophic Cardiomyopathy (HCM) Study

Cardiomyopathy, Hypertrophic

United Kingdom
Abbott Medical Devices

Withdrawn

Assessment of St Jude Medical Portico Re-sheathable Transapical Aortic Valve System (Portico TA EU)

Severe Symptomatic Aortic Stenosis

United Kingdom
Barts & The London NHS Trust
University College, London

Not yet recruiting

Immune Responsiveness and Outcome After Aortic Valve Surgery (Measure) (Measure)

Aortic Valve Disease | Surgery--Complications | Immune System Disorder

United Kingdom
Imperial College London
British Heart Foundation; Humboldt-Universität zu Berlin

Completed

Identifying an Ideal Cardiopulmonary Exercise Test Parameter (PVA)

Mitral Regurgitation | Left Ventricular Systolic Dysfunction

United Kingdom
University of Edinburgh
British Heart Foundation

Completed

The Role of Myocardial Fibrosis in Patients With Aortic Stenosis

Aortic Stenosis

United Kingdom
University of Leicester
University of Edinburgh

Recruiting

MRI in Randomised Cohorts of Asymptomatic AS

Aortic Stenosis, Severe

United Kingdom
Medtronic Bakken Research Center

Completed

Hancock II Ultra Porcine Bioprosthesis Hemodynamic Study

Aortic Heart Valve Diseases

Belgium, Netherlands, Italy, United Kingdom
Barts & The London NHS Trust

Recruiting

Atrial Functional Mitral Regurgitation and Tricuspid Regurgitation

Atrial Fibrillation | Functional Mitral Regurgitation | Functional Tricuspid Regurgitation

United Kingdom
Barts & The London NHS Trust

Terminated

Paced Dyssynchrony and Myocardial Perfusion IN apiCal Hcm (PINCHcm)

Hypertrophic Cardiomyopathy

United Kingdom
Imperial College London
British Heart Foundation

Recruiting

Electromechanically Optimised Right Ventricular Pacing In Hypertrophic Cardiomyopathy (EMORI-HCM) (EMORI-HCM)

Hypertrophic Cardiomyopathy | Hypertrophic Obstructive Cardiomyopathy

United Kingdom
corlife
Universitaire Ziekenhuizen KU Leuven; Hannover Medical School; Hospital Clinic... and other collaborators

Completed

Aortic Replacement Using Individualised Regenerative Allografts - ARISE (the "Surveillance") (ARISE)

Heart Valve Disease

Germany, Switzerland, Belgium, Italy, Netherlands, Spain, United Kingdom

Clinical Trials on Valve Disease, Heart in United Kingdom

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Denmark

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations