Clinical Trials on Vascular Anomaly in Czechia

Total 870 results

Pharming Technologies B.V.

Completed

A Phase 2 HAE Prophylaxis Study With Recombinant Human C1 Inhibitor

Hereditary Angioedema

United States, Canada, Czechia, Italy, Macedonia, The Former Yugoslav Republic of, Romania, Serbia
Novartis

Completed

Efficacy and Safety of Aliskiren 75 mg, 150 mg, and 300 mg in Elderly Patients With Essential Hypertension When Given With a Light Meal in a 8 Week Placebo-controlled Study

Hypertension

Slovakia, Italy, Netherlands, Argentina, Germany, Poland, Czech Republic, Iceland
St. Antonius Hospital

Completed

Antiplatelet Therapy for Patients Undergoing Transcatheter Aortic Valve Implantation (POPular-TAVI)

Myocardial Infarction | Stroke | Bleeding | Aortic Valve Disease

Netherlands, Belgium, Czechia, Luxembourg
Oxurion

Completed

A Study to Evaluate THR-149 Treatment for Diabetic Macular Oedema (KALAHARI)

Diabetes Mellitus | Diabetic Retinopathy | Diabetic Macular Edema

United States, France, United Kingdom, Spain, Germany, Italy, Slovakia, Czechia
Pharming Technologies B.V.

Recruiting

C1 Inhibitor Registry in the Treatment of Hereditary Angioedema (HAE) Attacks

Hereditary Angioedema

Germany, Bulgaria, Croatia, Czechia, France, Hungary, Italy, North Macedonia, Poland, Slovakia, Norway, Slovenia, Sweden
Biosense Webster, Inc.

Completed

RENABLATE-II Feasibility Study of Catheter Based Renal Denervation to Treat Resistant Hypertension - 157 (RENABLATE-II)

Hypertension, Renal

Czech Republic, Italy, New Zealand, Spain
Maquet Cardiovascular

Completed

Study Comparing Synthetic Vascular Grafts in Patients With Peripheral Artery Disease (PAD) Who Require Artery Bypass. (FINEST)

Peripheral Arterial Occlusive Disease

United States, Germany, Czechia
Wave Life Sciences Ltd.

Terminated

Efficacy and Safety Study of WVE-210201 (Suvodirsen) With Open-label Extension in Ambulatory Patients With Duchenne Muscular Dystrophy (DYSTANCE 51)

Duchenne Muscular Dystrophy

United States, Belgium, United Kingdom, Czechia, Canada, France, Italy, Sweden
The Medicines Company
The Cleveland Clinic

Completed

MDCO-216 Infusions Leading to Changes in Atherosclerosis: A Novel Therapy in Development to Improve Cardiovascular Outcomes - Proof of Concept Intravascular Ultrasound (IVUS), Lipids, and Other Surrogate Biomarkers Trial (PILOT)

Acute Coronary Syndrome

Poland, Netherlands, Hungary, Canada, Czechia
Shire

Completed

Sophisticated Assessment of Disease Burden in Patients With Fabry Disease (SOPHIA)

Fabry Disease

Finland, Sweden, Germany, Belgium, Czechia, Denmark
Terumo Europe N.V.
Cromsource

Completed

DIStal Versus COnventional RADIAL Access for Coronary Angiography and Intervention

Coronary Disease

Italy, Belgium, United Kingdom, Hungary, Japan, Czechia, Germany, Netherlands, North Macedonia, Switzerland
Kezar Life Sciences, Inc.

Completed

Open-label Extension to the Phase 2 Crossover Study (PRESIDIO) Evaluating KZR-616 in Patients With PM and DM.

Dermatomyositis | Polymyositis

United States, Czechia
General University Hospital, Prague
University of Iowa; Loyola University Chicago; Ministry of Health, Czech Republic and other collaborators

Unknown

The Prediction of Extent and Risk Profile of Coronary Atherosclerosis and Their Changes During Lipid-lowering Therapy Based on Non-invasive Techniques (PREDICT)

Coronary Artery Disease

United States, Czech Republic
Bayer

Completed

EXPERT, EXPosurE Registry RiociguaT in Patients With Pulmonary Hypertension (EXPERT)

Hypertension, Pulmonary

Turkey, Austria, Czechia, Russian Federation, Slovakia, Switzerland, Italy, Germany, United Kingdom, France, Belgium, Canada, Colombia, Greece, Luxembourg, Netherlands, Spain, Taiwan, Denmark, Sweden, Argentina, Portugal, Saudi Arabia, Austral... and more
Jazz Pharmaceuticals

Completed

A Safety, Efficacy and Tolerability Study of Sativex for the Treatment of Spasticity in Children Aged 8 to 18 Years

Cerebral Palsy

Czechia, Israel, United Kingdom
AOP Orphan Pharmaceuticals AG

Enrolling by invitation

A Prospective Non-interventional Observational Study to Observe Long-term Treatment and Outcomes in Pulmonary Arterial Hypertension (PAH) Patients (TripleTRE-NIS)

Pulmonary Arterial Hypertension

France, Spain, Germany, Italy, Hungary, Austria, Czechia, Poland, Romania
Stichting European Myeloma Network
Fondazione EMN Italy Onlus

Completed

COVID-19 Infection and Multiple Myeloma (EMN-COVID)

Covid19 | Multiple Myeloma | Corona Virus Infection

Czechia, Netherlands, United Kingdom, Belgium, Germany, Austria, Greece, Italy
Supernus Pharmaceuticals, Inc.
Solstice Neurosciences

Active, not recruiting

Efficacy and Safety Study of MYOBLOC® in the Treatment of Adult Lower Limb Spasticity

Spasticity

United States, Czechia
Boehringer Ingelheim

Completed

Treatment of Patients Undergoing Primary Unilateral Elective Total Knee or Hip Replacement With Dabigatran Etexilate

Arthroplasty, Replacement | Prevention of Venous Thromboembolism | Moderate Renal Impairment (CrCl 30-50 mL/Min)

Austria, Canada, Czechia, Finland, Netherlands, Sweden
Lung Biotechnology PBC

Completed

Dose-response Study of the Safety and Efficacy of Beraprost Sodium Modified Release (BPS-MR) in Patients With Pulmonary Arterial Hypertension (PAH)

Pulmonary Arterial Hypertension

United States, Belgium, Czechia, Germany, Ireland, Romania
Biosense Webster, Inc.

Completed

RENABLATE Feasibility Study CS156 (EC12-02) Study of Catheter Based Renal Denervation to Treat Resistant Hypertension

Hypertension, Renal

Belgium, Czech Republic, Italy, Australia, Denmark
Lung Biotechnology PBC

Completed

Extension of BPS-MR-PAH-203 in Pulmonary Arterial Hypertension (PAH) Patients

Pulmonary Arterial Hypertension

United States, Belgium, Czechia, Germany, Ireland, Romania
William Cook Europe
Cook Group Incorporated; MED Institute, Incorporated; William Cook Australia

Completed

Clinical Study to Assess Safety and Effectiveness of the Zenith® Dissection Endovascular System in Patients With Aortic Dissection

Aortic Dissection Involving the Descending Thoracic Aorta

Italy, Germany, Australia, Czech Republic, France
Molnlycke Health Care AB

Completed

A Multicenter, Post Marketing Clinical Follow up (PMCF) Investigation to Evaluate the Performance and Safety of a Soft Silicone Foam Dressing and to Evaluate the Performance of Standard Care in Exuding Venous Leg Ulcers

Venous Leg Ulcer (VLU)

Czech Republic
Boehringer Ingelheim

Completed

Efficacy and Tolerability CVI (A 12-week, Double-blind, Randomised, Placebo-controlled, Multicentre Trial (CVI)

Venous Insufficiency

Germany, Austria, Czech Republic
AOP Orphan Pharmaceuticals AG
GCP-Service International Ltd. & Co. KG; ANOVA CRO s.r.o.; PharmaLex Belgium; Aixial...

Recruiting

Initial Triple Therapy Including Parenteral Treprostinil vs Initial Double Oral Therapy in PAH Group I Patients (TripleTRE)

Pulmonary Arterial Hypertension

Austria, Spain, France, Germany, Italy, Czechia, Hungary, Poland, Portugal, Romania
Oncopeptides AB

Terminated

Study of Melphalan Flufenamide (Melflufen) + Dex With Bortezomib or Daratumumab in Patients With RRMM (ANCHOR)

Multiple Myeloma

United States, France, Spain, Czechia
INRESA Pharma
RCTs

Completed

The Sorbact® Antimicrobial Dressing in the Holistic Wound Management Of Diabetic Foot ulCers (Phase III Study) (ADHOC)

Foot Ulcer, Diabetic

France, Czechia, Poland
GlaxoSmithKline

Completed

Integrated Biomarker And Imaging Study - 2

Atherosclerosis

Netherlands, Belgium, Germany, Czechia, France, Austria, Spain, Norway, Poland, Denmark, Switzerland
Medtronic

Completed

Medtronic PSR TDD PMCF

Chronic Pain | Spasticity, Muscle

Belgium, Spain, Czechia, France, Netherlands, Slovenia, Switzerland, United Kingdom
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

A Study Comparing The Efficacy, Safety And Tolerability Of Latanoprost 75, 100 And 125 ug/ml To Xalatan In The Treatment Of Primary Open-Angle Glaucoma And Ocular Hypertension

Primary Open Angle Glaucoma | Ocular Hypertension

United Kingdom, France, Australia, Thailand, Portugal, Pakistan, Czechia, Greece
Lombard Medical

Completed

ARBITER-II: Aorfix™ Bifurcated Safety and Performance Trial: Phase II, Angulated Vessels (ARBITER-II)

Abdominal Aortic Aneurysm

Czech Republic, Germany, Poland, Spain, United Kingdom
European Myeloma Network
Janssen Research & Development, LLC

Active, not recruiting

Daratumumab, VELCADE (Bortezomib), Lenalidomide and Dexamethasone Compared to VELCADE, Lenalidomide and Dexamethasone in Subjects With Previously Untreated Multiple Myeloma (Perseus)

Multiple Myeloma

Norway, Denmark, Netherlands, Czechia, Australia, Turkey, Spain, Belgium, Switzerland, France, Greece, Italy, Poland
SurModics, Inc.

Active, not recruiting

Safety and Efficacy of the SurVeil™ Drug-Coated Balloon (TRANSCEND)

Peripheral Arterial Disease | Peripheral Vascular Disease | Femoropopliteal Artery Occlusion | Artery Disease, Peripheral

New Zealand, United States, Belgium, Latvia, Germany, Australia, Austria, Czechia, Italy
CENTOGENE GmbH Rostock

Completed

The Efficacy and Safety of Switch Between Agalsidase Beta to Agalsidase Alfa for Enzyme Replacement in Patients With Anderson-Fabry Disease (SWITCH)

Fabry Disease | Anderson-Fabry Disease | Fabry´s Disease

Argentina, Belgium, Croatia, Czechia, Denmark, France, Germany, United Kingdom
Bayer

Completed

Study to Investigate Adherence of Patients to Clodronate (Bonefos) Treatment (BONA)

Breast Neoplasms | Prostatic Neoplasms | Multiple Myeloma | Osteolysis

Czech Republic
ZOLL Circulation, Inc., USA

Completed

COOL-AMI EU Case Series Clinical Study

Acute Myocardial Infarction

Hungary, United Kingdom, Germany, Estonia, Poland, Serbia, Czechia, Lithuania
Fovea Pharmaceuticals SA

Completed

Safety and Efficacy Study of Topical Administration of FOV2304 (High Dose or Low Dose) for the Treatment of Center-involving Clinically Significant Macular Edema Associated With Diabetic Retinopathy

Diabetic Macular Edema

United States, Australia, Belgium, Czech Republic, France, Germany, Israel, Italy, Poland, Spain
Orchestra BioMed, Inc
Medtronic

Recruiting

BradycArdia paCemaKer With AV Interval Modulation for Blood prEssure treAtmenT (BACKBEAT)

Hypertension | Hypertension, Systolic | Hypertension,Essential

United States, Czechia, Spain, Hungary, Belgium
Austrian Forum Against Cancer

Completed

Bendamustine Plus Bortezomib Plus Dexamethasone in Relapsed or Refractory Multiple Myeloma (BBD)

Multiple Myeloma

Austria, Czech Republic
Novartis Pharmaceuticals

Active, not recruiting

Study of Efficacy and Safety of Secukinumab in Participants With Moderate-severe Rotator Cuff Tendinopathy

Rotator Cuff Tendinopathy

Argentina, United States, Slovakia, Chile, Malaysia, Canada, Portugal, Czechia, Bulgaria
UCB BIOSCIENCES GmbH
Aptiv Solutions

Completed

Alprostadil in Peripheral Arterial Occlusive Disease (PAOD) Stage IV (ESPECIAL)

Peripheral Arterial Occlusive Disease

Czechia, Germany, Mexico, Poland, Russian Federation, Ukraine
Jazz Pharmaceuticals

Completed

Trial to Evaluate the Effect of Nabiximols Oromucosal Spray on Clinical Measures of Spasticity in Participants With Multiple Sclerosis (RELEASE MSS1)

Spasticity in Participants With Multiple Sclerosis

Czechia, Poland
NHS National Waiting Times Centre Board
Stanford University; Catharina Ziekenhuis Eindhoven; Onze Lieve Vrouw Hospital; Brno University Hospital and other collaborators

Completed

Fractional Flow Reserve (FFR) Versus Instant Wave-Free Ratio (iFR)

Coronary Artery Disease | Plaque, Atherosclerotic

Netherlands, United States, Czech Republic, Belgium, Sweden
Pfizer

Completed

PF-00489791 For The Treatment Of Raynaud's

Peripheral Vascular Disease | Raynaud's Disease

Spain, United States, Czechia, Hungary, Poland, Korea, Republic of, Canada, Mexico, Germany, Colombia, Sweden
Kodiak Sciences Inc

Completed

A Study to Evaluate the Efficacy, Durability, and Safety of KSI-301 Compared to Aflibercept in Patients With Macular Edema Due to Retinal Vein Occlusion (RVO) (BEACON)

Macular Edema | Retinal Vein Occlusion

Spain, United States, Latvia, Israel, France, Italy, Hungary, Germany, Poland, Slovakia, Puerto Rico, Czechia
Aposcience AG
FGK Clinical Research GmbH

Completed

A Study to Evaluate Safety and Efficacy of APO-2 at Three Different Doses in Patients With Diabetic Foot Ulcer

Diabetic Foot Ulcer (DFU)

Austria, Czechia, Germany, Poland
NS Pharma, Inc.
Nippon Shinyaku Co., Ltd.

Active, not recruiting

Study to Assess the Safety and Efficacy of Viltolarsen in Ambulant Boys With DMD (RACER53-X)

Duchenne Muscular Dystrophy

Korea, Republic of, Chile, Japan, China, United Kingdom, Netherlands, Spain, Norway, Russian Federation, Australia, Greece, Italy, New Zealand, Turkey, Mexico, Czechia, Canada
CeleCor Therapeutics

Recruiting

A Phase 3 Study of Zalunfiban in Subjects With ST-elevation MI (CELEBRATE)

ST-elevation Myocardial Infarction (STEMI)

Netherlands, Canada, Czechia, France, Hungary, Romania
Daiichi Sankyo, Inc.
Daiichi Sankyo Europe, GmbH, a Daiichi Sankyo Company

Completed

Use of the Combination of Olmesartan and Hydrochlorothiazide in Essential Hypertension

Essential Hypertension

France, Poland, Ukraine, Germany, Spain, Bulgaria, Czechia

Clinical Trials on Vascular Anomaly in Czechia

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