Clinical Trials on Vulval Intraepithelial Neoplasia

Total 107067 results

University of Manchester
British Society for the Study of Vulval Disease

Completed

Early Detection of Vulval CAncer Through Self-Examination (EDuCATE): Intervention Study

Vulvar Cancer | Lichen Planus | Vulvar Lichen Sclerosus | Self-Examination | Vulval Intraepithelial Neoplasia | Vulval Cancer | Vulval Intraepithelial Neoplasia With Lichen Sclerosus

United Kingdom
Sidney Kimmel Comprehensive Cancer Center at Johns...
Frantz Viral Therapeutics, LLC

Active, not recruiting

Artesunate Ointment for the Treatment of High Grade Vulvar Intraepithelial Neoplasia (HSIL VIN2/3) (ART-VIN)

Vulvar Diseases | Vulvar Dysplasia | HPV-Related Vulvar Intraepithelial Neoplasia | Preinvasive Vulvar Disease | Vulva Intraepithelial Neoplasia

United States
ViMREX GmbH
Frankfurter Institut für Klinische Krebsforschung IKF GmbH am Krankenhaus...

Active, not recruiting

Clinical Trial With Local Decitabine Treatment of HPV-Induced VIN Grade 2/3 (DelVIN) (DelVIN)

Vulvar Intraepithelial Neoplasia Grade 2 | Vulvar Intraepithelial Neoplasia Grade 3

Germany
National Cancer Institute (NCI)

Terminated

Immunotherapy With E7 T Cell Receptor T Cells for Vulvar High-Grade Squamous Intraepithelial Lesions

Neoplasms, Squamous Cell | Squamous Lntraepithelial Lesions of Vulva | Vulvar HSIL

United States
Maruho Co., Ltd.

Completed

Pharmacodynamics, Safety/Tolerability and Efficacy of Topical Omiganan in Patients With uVIN

Usual Type Vulval Intraepithelial Neoplasia (uVIN)

Netherlands
Medical University of Graz
Austrian Science Fund (FWF)

Completed

Primary Imiquimod Treatment Versus Surgery for Vulvar Intraepithelial Neoplasia (PITVIN)

Vulvar Intraepithelial Neoplasia

Austria
University of Colorado, Denver
Stryker Instruments

Completed

Ultrasonic Aspiration Versus CO2 Laser Ablation for the Treatment of Vulvar Intraepithelial Neoplasia

Vulvar Intraepithelial Neoplasia (VIN)

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Terminated

HPV Vaccine Therapy in Interrupting Progression in Patients With High-Grade Vulvar or Anal Lesions

High Grade Anal Canal Intraepithelial Neoplasia | High Grade Vulvar Squamous Intraepithelial Lesion

United States
Institut de Cancérologie de Lorraine

Recruiting

Evaluation of New Diagnostic Tool Using Fluorescence to Detect High-grade Vulvar Intraepithelial Neoplasia (PhotodiVIN)

Vulvar Intraepithelial Neoplasia | Vulvar High Grade Squamous Intraepithelial Lesion | Differentiated Vulvar Intraepithelial Neoplasia

France
Inovio Pharmaceuticals

Completed

Evaluation of VGX-3100 and Electroporation Alone or in Combination With Imiquimod for the Treatment of HPV-16 and/or HPV-18 Related Vulvar HSIL (Also Referred as: VIN 2 or VIN 3)

Human Papillomavirus (HPV) | Vulvar Dysplasia | Vulvar Intraepithelial Neoplasia (VIN) | Vulvar High Grade Squamous Intraepithelial Lesion (HSIL) | VIN2 | VIN3 | Pre-cancerous Lesions of the Vulva

United States
St.Gallen University of Applied Sciences
Medical University of Vienna; University Hospital Inselspital, Berne; University... and other collaborators

Completed

The Impact of the "WOMAN-PRO II Program" on Patients With Vulvar Neoplasia to Minimize Post-surgical Symptom Prevalence (WOMAN-PROII)

Vulvar Cancer | Vulvar Intraepithelial Neoplasia

Switzerland
Jun Zhang
Xiamen Innovax Biotech Co., Ltd; Beijing Wantai Biological Pharmacy Enterprise...

Recruiting

The Durability of Protection and Immuno-persistence Study of a Recombinant HPV 16/18 Bivalent Vaccine in Female

Cervical Cancer | Cervical Intraepithelial Neoplasia | Vaginal Intraepithelial Neoplasia | Vulvar Intraepithelial Neoplasia | Persistent Infection

China
Centre Hospitalier Universitaire de Nice

Terminated

Interest of the Confocal Microscope in the Diagnosis of Epidermoid Carcinoma of the Vulva and Their Precursors

Vulvar Intraepithelial Neoplasia | Vulvar Mucosa Lesions

France
Xiamen Innovax Biotech Co., Ltd
Jiangsu Province Centers for Disease Control and Prevention; Dongtai City Centers...

Completed

Lot Consistency Clinical Trial of of Recombinant HPV Bivalent Vaccine in 9 to14 Years Old Healthy Female

Cervical Cancer | Cervical Intraepithelial Neoplasia | Vaginal Intraepithelial Neoplasia | Vulvar Intraepithelial Neoplasia | Persistent Infection

China
Jun Zhang
Xiamen Innovax Biotech Co., Ltd; Beijing Wantai Biological Pharmacy Enterprise...

Completed

Immuno-persistence Study of a Recombinant Human Papillomavirus 16/18 Bivalent Vaccine in Preadolescent Girls

Cervical Cancer | Cervical Intraepithelial Neoplasia | Vaginal Intraepithelial Neoplasia | Vulvar Intraepithelial Neoplasia | Persistent Infection

China
Jun Zhang
Xiamen Innovax Biotech Co., Ltd; Beijing Wantai Biological Pharmacy Enterprise...

Completed

A Bridging Study of a Recombinant Human Papillomavirus 16/18 Bivalent Vaccine in Preadolescent Girls

Cervical Cancer | Cervical Intraepithelial Neoplasia | Vaginal Intraepithelial Neoplasia | Vulvar Intraepithelial Neoplasia | Persistent Infection

China
Jun Zhang
Xiamen Innovax Biotech Co., Ltd; Beijing Wantai Biological Pharmacy Enterprise...

Recruiting

The Durability of Protection Study of a Recombinant HPV 16/18 Bivalent Vaccine in Female

Cervical Cancer | Cervical Intraepithelial Neoplasia | Vaginal Intraepithelial Neoplasia | Vulvar Intraepithelial Neoplasia | Persistent Infection

China
Jun Zhang
Xiamen Innovax Biotech Co., Ltd; Beijing Wantai Biological Pharmacy Enterprise...

Active, not recruiting

Immuno-persistence Study of a Recombinant Human Papillomavirus 16/18 Bivalent Vaccine in Preadolescent Girls (54m)

Cervical Cancer | Cervical Intraepithelial Neoplasia | Vaginal Intraepithelial Neoplasia | Vulvar Intraepithelial Neoplasia | Persistent Infection

China
University of Basel
University Hospital Inselspital, Berne; Foundation Cancer Research Switzerland

Unknown

A New Patient Reported Outcome Instrument to Assess Symptom Experience in Women With Vulvar Neoplasms (WOMAN-PRO) (WOMAN-PRO)

Women With Vulvar Intraephitelial Neoplasia or Vulvar Cancer

Switzerland, Germany
Northwestern University
National Cancer Institute (NCI)

Withdrawn

Colposcopy and High Resolution Anoscopy in Screening For Anal Dysplasia in Patients With Cervical, Vaginal, or Vulvar Dysplasia or Cancer

Cervical Intraepithelial Neoplasia Grade 1 | Cervical Intraepithelial Neoplasia Grade 2 | Cervical Intraepithelial Neoplasia Grade 3 | Stage III Vulvar Cancer | Recurrent Cervical Cancer | Recurrent Vaginal Cancer | Recurrent Vulvar Cancer | Stage 0 Cervical Cancer | Stage 0 Vaginal Cancer | Stage 0 Vulvar... and other conditions
Integra LifeSciences Corporation

Active, not recruiting

Cavitronic Ultrasonic Surgical Aspiration (CUSA) Women's Health Study

Condylomata Acuminata | Vulvar Intraepithelial Neoplasia

United States
Xiamen University
Ministry of Science and Technology of the People´s Republic of China; Xiamen... and other collaborators

Completed

Efficacy and Immunogenicity Study of Recombinant Human Papillomavirus Bivalent（Type 16/18 ）Vaccine

Cervical Cancer | Cervical Intraepithelial Neoplasia | Vaginal Intraepithelial Neoplasia | Vulvar Intraepithelial Neoplasia | Persistent Infection

China
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Biospecimen Collection and Testing for the Prevalence of Anal Dysplasia and Anal Cancer in Patients With Cervical, Vaginal and Vulvar Dysplasia and Cancer

Cervical Intraepithelial Neoplasia | Cervical Adenocarcinoma | Cervical Squamous Cell Carcinoma, Not Otherwise Specified | Vaginal Adenocarcinoma | Vulvar Intraepithelial Neoplasia | Stage I Cervical Cancer AJCC v8 | Stage IA Cervical Cancer AJCC v8 | Stage IA1 Cervical Cancer AJCC v8 | Stage IA2 Cervical... and other conditions

United States
University Women's Hospital Tübingen

Completed

Electrochemotherapy for the Inoperable Vulva Carcinoma

Advanced Inoperable Vulva Carcinoma

Germany
Brookdale University Hospital Medical Center

Unknown

Multispectral Digital Colposcope With Probe for Detection of Cervical Intraepithelial Neoplasia (MDCwProbe)

Carcinoma in Situ of Uterine Cervix | Cervical Intraepithelial Neoplasias | High Grade Cervical Intraepithelial Neoplasia

United States
Leiden University Medical Center
University Medical Center Groningen; Erasmus Medical Center

Not yet recruiting

Neo-adjuvant Pembrolizumab in Vulvar Squamous Cell Carcinoma: a Clinical Proof-of-concept Study (Apollo)

Squamous Cell Cancer | Vulva Cancer | Vulva Neoplasm
Krankenhaus Barmherzige Schwestern Linz
Medical University of Vienna

Completed

TRICIN: Prospective Study on the Efficacy of Single Topical Trichloroacetic Acid (TCA) 85% in the Treatment of Cervical Intraepithelial Neoplasia (CIN 1/2) (TRICIN)

Cervical Intraepithelial Neoplasia Grade 1 | Cervical Intraepithelial Neoplasia Grade 2

Austria
The Netherlands Cancer Institute

Recruiting

Treatment of Locally Advanced VULvar CArcinoma in a Neoadjuvant Setting With Carboplatin and Paclitaxel Chemotherapy (VULCANize) (VULCANize)

Locally Advanced, Squamous Cell Carcinoma of the Vulva

Netherlands
The Netherlands Cancer Institute

Recruiting

Treatment of Metastatic Vulvar Carcinoma With Carboplatin and Paclitaxel Chemotherapy (CRAVAT)

Metastatic Squamous Cell Carcinoma of the Vulva

Netherlands
Coordinación de Investigación en Salud, Mexico
University of Guadalajara; Instituto Mexicano del Seguro Social

Completed

Topical Interferon Alfa 2b and Mitomycin C in Conjunctival-Corneal Intraepithelial Neoplasia

Conjunctival Intraepithelial Neoplasia | Corneal Intraepithelial Neoplasia

Mexico
Genexine, Inc.

Completed

Safety of GX-188E DNA Therapeutic Vaccine Administered by Electroporation to Cervical Intraepithelial Neoplasia Grade 3 (CIN3)

Cervical Intraepithelial Neoplasia 3

Korea, Republic of
Nykode Therapeutics ASA
Theradex; Vaccibody AS

Completed

An Exploratory Safety and Immunogenicity Study of HPV16+ Immunotherapy VB10.16 in Women With HSIL; CIN 2/3)

High Grade Cervical Intraepithelial Neoplasia

Germany
University of Alabama at Birmingham
National Cancer Institute (NCI)

Completed

An Alternative Treatment for Cervical Intraepithelial Neoplasia Using the Focal Loop Electrosurgical Excision Procedure

High-grade Cervical Intraepithelial Neoplasia

United States
Barretos Cancer Hospital
M.D. Anderson Cancer Center; National Cancer Institute (NCI); William Marsh Rice...

Unknown

HRME in the Screening of Cervical Cancer Precursor Lesions in Brazil (UH3 - Brazil) (UH3)

Cervical Cancer | Neoplasm Cervix | Intraepithelial Neoplasia | Intraepithelial Neoplasm, Cervical

Brazil
BioLeaders Corporation

Unknown

A Trial to Evaluate the Efficacy and Safety of BLS-ILB-E710c in Patients With Cervical Intraepithelial Neoplasia 2/3 (CIN2/3)

Cervical Intraepithelial Neoplasia Grade 2/3

Korea, Republic of
University Medical Centre Maribor

Recruiting

The Role of FAM19A4 and Hsa-mir-124 Methylation in Predicting Prognosis of Untreated Cervical Intraepithelial Neoplasia 2 (CIN 2)

Cervical Intraepithelial Neoplasia Grade 2 | DNA Methylation

Slovenia
Jinan Military General Hospital

Unknown

Nonneoplastic Epithelial Disorders of Vulva and High Intensity Focused Ultrasound

Vulva Intraepithelial Nonneoplastic

China
National Cancer Institute (NCI)

Terminated

Photodynamic Therapy Using Lutetium Texaphyrin in Treating Patients With Cervical Intraepithelial Neoplasia

Cervical Cancer | Cervical Intraepithelial Neoplasia Grade 2 | Cervical Intraepithelial Neoplasia Grade 3

United States
Medtronic - MITG

Completed

A Safety and Tolerability of Circumferential Anal Canal Radiofrequency Ablation For Anal Intraepithelial Neoplasia

Anal Intraepithelial Neoplasia (AIN) | High-grade Squamous Intraepithelial Lesions (HSIL)

United States
Genexine, Inc.

Unknown

Safety and Efficacy of GX-188E DNA Therapeutic Vaccine Administered by Electroporation After Observation (GX-188E)

Cervical Intraepithelial Neoplasia 3

Korea, Republic of
AGO Research GmbH

Not yet recruiting

Pembrolizumab in Combination With Lenvatinib in Patients With Recurrent, Persistent, Metastatic or Locally Advanced Vulvar Cancer Not Amenable to Curative Surgery or Radiotherapy (PIERCE)

Recurrent Vulvar Cancer | Persistent Vulvar Cancer | Metastatic Vulva Cancer | Locally Advanced Vulvar Cancer
Tufts Medical Center

Not yet recruiting

SLN Mapping and ICG Dye for Vulvar Cancer

Vulva Cancer

United States
University of Pittsburgh
National Cancer Institute (NCI)

Completed

A Pilot Study of Lycopene Supplementation in Prostatic Intraepithelial Neoplasia

Prostatic Intraepithelial Neoplasia

Trinidad and Tobago
GTx

Completed

A Chemoprevention Study of an Investigational Drug in Men With High Grade Prostate Intraepithelial Neoplasia (PIN)

Prostatic Intraepithelial Neoplasia

United States
Quadram Institute Bioscience

Completed

Broccoli, Peas and PIN

Prostatic Intraepithelial Neoplasia
Maternal and Child Health Hospital of Hubei Province

Completed

Methylene Blue Injection for Nonneoplastic Epithelial Disorders of Vulva (NNEDsMB)

Nonneoplastic Epithelial Disorders of Vulva
Huazhong University of Science and Technology

Recruiting

Comparison of pCLE and EB in Gastric Lesion Diagnosis

Early Gastric Cancer | Low Grade Intraepithelial Neoplasia | High Grade Intraepithelial Neoplasia | Gastric Intraepithelial Neoplasia

China
Shandong University

Unknown

Detection of Early Esophageal Squamous Neoplasia

Esophageal Squamous Intraepithelial Neoplasia

China
Rigshospitalet, Denmark
Aarhus University Hospital

Recruiting

Optical Guided Sentinel Node Biopsy for Staging of Vulvar Cancer (SENTIVUC II)

Sentinel Lymph Node | Vulva Cancer

Denmark
Diana Zach
Sahlgrenska University Hospital, Sweden; University Hospital, Linkoeping; Skane...

Completed

Sentinel Node Extended in Squamous Cell Vulvar Cancer (SNEX)

Sentinel Lymph Node | Vulva Cancer

Sweden

Clinical Trials on Vulval Intraepithelial Neoplasia

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