Clinical Trials on Vulvar Intraepithelial Neoplasia Grade 2

Total 1957 results

University of Southern California
National Cancer Institute (NCI); Brooklyn ImmunoTherapeutics, LLC

Active, not recruiting

IRX-2 Regimen in Treating Women With Cervical Squamous Intraepithelial Neoplasia 3 or Squamous Vulvar Intraepithelial Neoplasia 3

Cervical Squamous Cell Carcinoma In Situ | Vulvar High Grade Squamous Intraepithelial Lesion

United States
Antiva Biosciences

Completed

Study of Topical ABI-1968 in Subjects With Precancerous Cervical Lesions From Human Papillomavirus (HPV) Infection.

Cervical Cancer | Human Papilloma Virus | HSIL, High Grade Squamous Intraepithelial Lesions | Cervical Dysplasia | HSIL of Cervix | High-Grade Cervical Intraepithelial Neoplasia | HIV Negative | CIN - Cervical Intraepithelial Neoplasia | Cervical Neoplasm

South Africa
Medtronic - MITG

Completed

A Trial of Radiofrequency Ablation for Anal Intraepithelial Neoplasia Using the HALO Ablation System (AIN)

HIV-negative Subjects With Intra-anal Intraepithelial Neoplasia Containing High-Grade Squamous Intraepithelial Lesions

United States
Peking University People's Hospital
BeijingNewBiorayTechnologyCo.,Ltd.; Hangzhou Newhorizon Health Technology Co...

Active, not recruiting

Primary Cervical Cancer Screening by Self-sampling HPV Test (PREVENT)

Cervical Cancer | Cervical Adenocarcinoma | Cervical Squamous Cell Carcinoma | Human Papillomavirus Infection | Adenocarcinoma in Situ | Low-Grade Squamous Intraepithelial Lesions | High-Grade Squamous Intraepithelial Lesions | Cervical Intraepithelial Neoplasia Grade II | Cervical Intraepithelial Neoplasia... and other conditions

China
Integra LifeSciences Corporation

Active, not recruiting

Cavitronic Ultrasonic Surgical Aspiration (CUSA) Women's Health Study

Condylomata Acuminata | Vulvar Intraepithelial Neoplasia

United States
Muğla Sıtkı Koçman University

Completed

Evaluation of Thioldisulfide Balance in Cervical Preinvasive Lesions

Oxidative Stress | Low Grade Squamous Intraepithelial Lesion | High-Grade Squamous Intraepithelial Lesions

Turkey
University of Aarhus
National Cancer Institute (NCI); University of Virginia; University of Cambridge and other collaborators

Active, not recruiting

Biomarkers Predictive for Cervical Intraepithelial Neoplasia Grade 2 (CIN2) Evolvement

Cervical Intraepithelial Neoplasia Grade 2 (CIN2)

Denmark
Sidney Kimmel Comprehensive Cancer Center at Johns...
National Cancer Institute (NCI)

Recruiting

HPV DNA Vaccine Via Electroporation for HPV16 Positive Cervical Neoplasia

Human Papillomavirus Type 16 | Cervical Intraepithelial Neoplasia Grade II | Cervical Intraepithelial Neoplasia, Grade III

United States
DySIS Medical Inc.

Completed

IMproved PRactice Outcomes and Value Excellence in Colposcopy (IMPROVE-COLPO)

High Grade Cervical Intraepithelial Neoplasia

United States
David Finch
Lancashire Teaching Hospitals NHS Foundation Trust

Not yet recruiting

COrSIcA: Disease Measurement

Anal Intraepithelial Neoplasia | Anal High-grade Squamous Intraepithelial Lesion | Anal HSIL
Inovio Pharmaceuticals

Completed

REVEAL 2 Trial (Evaluation of VGX-3100 and Electroporation for the Treatment of Cervical HSIL)

Cervical Dysplasia | Cervical High Grade Squamous Intraepithelial Lesion | HSIL

United States, Spain, Lithuania, Estonia, South Africa, Argentina, Brazil, Finland, Poland, Puerto Rico
Evangelisches Krankenhaus Düsseldorf

Completed

ESD Versus EMR for Treatment of Early Barrett's Adenocarcinoma

Barrett Adenocarcinoma | High Grade Intraepithelial Neoplasia

Germany
European Institute of Oncology

Not yet recruiting

Evaluation of the PreCursor-M+® in CIN2

Cervical Intraepithelial Neoplasia Grade 2

Italy
University Hospital, Geneva

Completed

The HPV Self-test as a Test of Cure in Madagascar

Human Papilloma Virus Infection | Cervical Intraepithelial Neoplasia Grade 2/3

Madagascar
University of Washington
National Cancer Institute (NCI)

Completed

Home-Based or Clinic-Based Human Papillomavirus (HPV) Screening

Cervical Carcinoma | Human Papillomavirus Infection | Health Status Unknown | Cervical Intraepithelial Neoplasia Grade 2/3 | Stage 0 Cervical Cancer | Atypical Squamous Cell of Undetermined Significance | Low Grade Cervical Squamous Intraepithelial Neoplasia

United States
Saint Thomas Hospital, Panama

Completed

Observational vs. Ablative Treatment for Low-grade Squamous Intraepithelial Lesions.

LSIL, Low-Grade Squamous Intraepithelial Lesions

Panama
University of Wisconsin, Madison
Wisconsin Partnership Program

Recruiting

Lopinavir/Ritonavir in PLWH With High-Grade AIN

High-Grade Anal Intraepithelial Neoplasia

United States
Xiamen University
Ministry of Science and Technology of the People´s Republic of China; Xiamen... and other collaborators

Completed

Efficacy and Immunogenicity Study of Recombinant Human Papillomavirus Bivalent（Type 16/18 ）Vaccine

Cervical Cancer | Cervical Intraepithelial Neoplasia | Vaginal Intraepithelial Neoplasia | Vulvar Intraepithelial Neoplasia | Persistent Infection

China
Lei Li

Unknown

DNA Methylation for Screening Uterine Cervical Lesions

DNA Methylation | Uterine Cervical Cancer | High Grade Squamous Intraepithelial Lesions | Low Grade Squamous Intraepithelial Lesions

China
Lei Li

Unknown

DNA Methylation for Screening Uterine Cervical Lesions: A Case-control Study

DNA Methylation | Uterine Cervical Cancer | High Grade Squamous Intraepithelial Lesions | Low Grade Squamous Intraepithelial Lesions

China
Antiva Biosciences

Completed

Study of Topical ABI-1968 in Subjects With Precancerous Cervical Lesions From Human Papillomavirus (HPV) Infection

Cervical Cancer | Cervical Intraepithelial Neoplasia | CIN | Human Papilloma Virus | Cervical Dysplasia | HSIL of Cervix | Cervical Neoplasm | HSIL | High-Grade Squamous Intraepithelial Lesions | High-grade Cervical Intraepithelial Neoplasia

United States, Australia
AIDS Malignancy Consortium
National Cancer Institute (NCI); The Emmes Company, LLC; Inovio Pharmaceuticals

Active, not recruiting

VGX-3100 and Electroporation in Treating Patients With HIV-Positive High-Grade Anal Lesions

Anal Intraepithelial Neoplasia | High Grade Squamous Intraepithelial Neoplasia | HIV Positivity | Human Papillomavirus-16 Positive | Human Papillomavirus-18 Positive

United States, Puerto Rico
Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co...

Completed

Aminolaevulinic Acid Photodynamic Therapy for HPV+ Low Grade Cervical Intraepithelial Neoplasia (LSIL;CIN1)

Cervical Intraepithelial Neoplasia | Papillomavirus Infections | Low-Grade Squamous Intraepithelial Lesions

China
Charles University, Czech Republic

Not yet recruiting

The Adjuvant Effect of HPV Vaccination on Recurrence of Cervical Precancer or Carcinoma in Women Undergoing Conization

Recurrence | Cervical Intraepithelial Neoplasia Grade 2/3

Czechia
Xiuli Zuo

Active, not recruiting

Artificial Intelligence for Determination of Gastroscopy Surveillance Intervals

Early Gastric Cancer | Gastric Cancer | Helicobacter Pylori Infection | Intestinal Metaplasia | Atrophic Gastritis | Low Grade Intraepithelial Neoplasia | High Grade Intraepithelial Neoplasia

China
Khon Kaen University

Terminated

Cryotherapy for Human Papillomavirus Clearance in Biopsy-confirmed Cervical Low-grade Squamous Intraepithelial Lesions (Cryotherapy)

Human Papillomavirus Clearance at 12 Months

Thailand
University Women's Hospital Tübingen

Completed

Electrochemotherapy for the Inoperable Vulva Carcinoma

Advanced Inoperable Vulva Carcinoma

Germany
Gloucestershire Hospitals NHS Foundation Trust

Suspended

Evaluation of the Role of Vibrational Spectroscopy in the Assessment of Vulval Disease (Vulval VS)

Lichen Sclerosus | Squamous Cell Carcinoma | Normal Vulval Skin | High Grade Dysplasia - Usual Type ('VIN 2-3') | High Grade Dysplasia - Differentiated Type ('VIN 2-3') | Epithelial Hyperplasia Without Atypia | Atypia Not Otherwise Specified/ Low Grade Dysplasia ('VIN 1') | Pagets Disease of the...

United Kingdom
Leiden University Medical Center
University Medical Center Groningen; Erasmus Medical Center

Not yet recruiting

Neo-adjuvant Pembrolizumab in Vulvar Squamous Cell Carcinoma: a Clinical Proof-of-concept Study (Apollo)

Squamous Cell Cancer | Vulva Cancer | Vulva Neoplasm
Sidney Kimmel Comprehensive Cancer Center at Johns...
National Cancer Institute (NCI); National Institutes of Health (NIH)

Completed

Therapeutic Vaccination for Patients With HPV16+ Cervical Intraepithelial Neoplasia (CIN2/3)

HPV16 Positive | Cervical Intraepithelial Neoplasia (CIN 2/3)

United States
Universidad de Antioquia
Barts and the London School of Medicine and Dentistry; Instituto Colombiano... and other collaborators

Completed

Optimal Strategy for the Management of ASCUS Cytology in Health Care Services of Medellin, Colombia (ASCUS-COL)

Cervical Cancer | Cervical Abnormalities | Cervical Intraepithelial Neoplasia Grade 2/3

Colombia
Miquel Angel Pavon Ribas
Catalan Institute of Health; Hospital del Mar

Recruiting

A Study to Assess the Reduction of Human Papillomavirus (HPV) Viral Infectivity and Transmission in HPV-Positive Women After Vaccination With 9vHPV (RIFT-HPV) (RIFT-HPV)

Cervical Intraepithelial Neoplasia Grade I/ II/ III (CIN I/II/III) | Human Papillomavirus (HPV) Infections | High-risk HPV | HPV-16/ 18

Spain
National Health Research Institutes, Taiwan

Completed

A Multi-center Survey of HPV in Cervical Intraepithelial Neoplasia (CIN) With Longitudinal Follow-up of LSIL Cases

Cervical Cancer | Human Papillomavirus | Low-grade Squamous Intraepithelial Lesion,

Taiwan
The Netherlands Cancer Institute

Recruiting

Treatment of Locally Advanced VULvar CArcinoma in a Neoadjuvant Setting With Carboplatin and Paclitaxel Chemotherapy (VULCANize) (VULCANize)

Locally Advanced, Squamous Cell Carcinoma of the Vulva

Netherlands
The Netherlands Cancer Institute

Recruiting

Treatment of Metastatic Vulvar Carcinoma With Carboplatin and Paclitaxel Chemotherapy (CRAVAT)

Metastatic Squamous Cell Carcinoma of the Vulva

Netherlands
University Hospital, Strasbourg, France

Unknown

Diagnostic and Prognostic Value of p16INK4a Expression in Low Grade Squamous Intraepithelial Lesions of the Cervix.

Cervical Intraepithelial Neoplasia Grade 1 (CIN 1)

France
University Fernando Pessoa

Recruiting

ANAL PRECANCEROUS LESIONS IN HIGH-RISK PATIENTS. (PACCO)

HSIL, High Grade Squamous Intraepithelial Lesions | AIN3 | AIN2

Portugal
National Cancer Institute (NCI)

Completed

SGN-00101 Vaccine in Treating Human Papillomavirus in Patients Who Have Abnormal Cervical Cells

Cervical Cancer | High-grade Squamous Intraepithelial Lesion | Atypical Squamous Cells of Undetermined Significance | Low-grade Squamous Intraepithelial Lesion

United States
RinuaGene Biotechnology Co., Ltd.

Not yet recruiting

A Study in Subjects With Human Papillomavirus 16 or 18 Associated Cervical Intraepithelial Neoplasia Grade 2 or 3

Cervical Intraepithelial Neoplasia Grade 2/3 | Human Papillomavirus Associated Intraepithelial Neoplasia | Human Papillomavirus Type 16 Infection | Human Papillomavirus Type 18 Infection
Medical University of Vienna

Completed

Confocal Laser Endomicroscopy and Endoscopic Mucosal Resection

Barrett's Mucosa With High Grade Intraepithelial Neoplasia (HGIEN)

Austria
AGO Research GmbH

Not yet recruiting

Pembrolizumab in Combination With Lenvatinib in Patients With Recurrent, Persistent, Metastatic or Locally Advanced Vulvar Cancer Not Amenable to Curative Surgery or Radiotherapy (PIERCE)

Recurrent Vulvar Cancer | Persistent Vulvar Cancer | Metastatic Vulva Cancer | Locally Advanced Vulvar Cancer
National Cancer Institute (NCI)

Terminated

Immunotherapy With E6 T Cell Receptor (TCR) T Cells for Vulvar High-Grade Squamous Intraepithelial Lesions

Human Papillomavirus | HPV-16 | High Grade Squamous Intraepithelial Lesion

United States
University of Witwatersrand, South Africa
Merck Sharp & Dohme LLC

Completed

Randomized, Double Blind Trial of the Quadrivalent HPV Vaccine to Improve Responses to LEEP Treatment of Cervical HSIL

Cervical High Grade Squamous Intraepithelial Lesion
Southwest Oncology Group
National Cancer Institute (NCI)

Withdrawn

S0212 Celecoxib in Treating Patients With High-Grade Squamous Intraepithelial Lesions of the Cervix

Stage 0 Cervical Cancer | High-grade Squamous Intraepithelial Lesion
Gynecologic Oncology Group
National Cancer Institute (NCI)

Terminated

Megestrol in Treating Patients With Endometrial Neoplasia or Endometrial Hyperplasia

High Grade Squamous Intraepithelial Neoplasia | Stage 0 Uterine Corpus Cancer

United States
Brugmann University Hospital

Completed

A Prolongation of a Clinical Study to Evaluate the Efficacy of an Aqueous Gel Containing 2% (w/w) of Cidofovir, Directly Applied on the Cervix Exhibiting High Grade Squamous Intraepithelial Lesions.

High Grade Cervical Epithelial Neoplasia (CIN2+)

Belgium
Tigris Pharmaceuticals

Completed

Safety and Efficacy of A-007 Topical Gel in the Treatment of High-Grade Squamous Intraepithelial Lesions (HSIL) of the Cervix

Cervical Intraepithelial Neoplasia | Uterine Cervical Dysplasia

United States
Tufts Medical Center

Not yet recruiting

SLN Mapping and ICG Dye for Vulvar Cancer

Vulva Cancer

United States
Tigris Pharmaceuticals

Completed

A Two-Stage Phase 2 Study Of A-007 Topical Gel in High-Grade Squamous Intraepithelial Lesions (HSIL) (TG-003)

Cervical Intraepithelial Neoplasia | Uterine Cervical Dysplasia

United States
Rigshospitalet, Denmark
Aarhus University Hospital

Recruiting

Optical Guided Sentinel Node Biopsy for Staging of Vulvar Cancer (SENTIVUC II)

Sentinel Lymph Node | Vulva Cancer

Denmark

Clinical Trials on Vulvar Intraepithelial Neoplasia Grade 2

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