Clinical Trials on WHO Grade IV Gliomas

Total 507 results

Seoul National University Hospital

Unknown

Permeability Map to Distinguish Progression From Pseudoprogression in High-Grade Glioma

High Grade Glioma

Korea, Republic of
Oncoscience AG
Heinrich-Heine University, Duesseldorf; University of Cologne; Universitätsklinikum... and other collaborators

Completed

Nimotuzumab in Children With HGG

High Grade Glioma

Germany
Jennie Taylor
University of Minnesota

Active, not recruiting

Neo-adjuvant Evaluation of Glioma Lysate Vaccines in WHO Grade II Glioma

Glioma | Malignant Glioma | Oligodendroglioma | Astrocytoma, Grade II | Glioma, Astrocytic | Oligoastrocytoma, Mixed

United States
Universitaire Ziekenhuizen KU Leuven
Carl Zeiss Meditec AG; Imec

Recruiting

HyperSpectral Imaging in Low Grade Glioma (HSI-LGG-2019)

Low Grade Glioma of Brain

Belgium
Beijing Tiantan Hospital

Unknown

The Impact of Anesthesia on High- Grade Glioma Patients

Anesthesia, Outcome, High-grade Glioma

China
Tocagen Inc.

Withdrawn

A Study of the Safety of Toca 511, a Retroviral Replicating Vector, Combined With Toca FC in Subjects With Newly Diagnosed High Grade Glioma Receiving Standard of Care (Toca7)

Newly Diagnosed High Grade Glioma (HGG)
National Cancer Institute (NCI)

Completed

Valproic Acid With Temozolomide and Radiation Therapy to Treat Brain Tumors

Brain Tumors | High Grade Gliomas

United States
Dana-Farber Cancer Institute
Novartis; Pediatric Oncology Experimental Therapeutics Investigators' Consortium

Completed

Everolimus (RAD001) for Children With Chemotherapy-Refractory Progressive or Recurrent Low-Grade Gliomas

Glioma | Astrocytoma | Low-grade Glioma

United States
Tata Memorial Centre
Bhabha Atomic Research Centre (BARC)

Recruiting

A Study of Chlorophyllin for the Management of Brain Radio-necrosis in Patients With Diffuse Glioma (CHROME)

Glioblastoma Multiforme | High Grade Glioma | Diffuse Glioma | Radionecrosis of Brain

India
National Cancer Institute (NCI)

Completed

Rituximab Plus Interleukin-2 in Treating Patients With Hematologic Cancer

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Diffuse Small Cleaved Cell Lymphoma and other conditions

United States
Case Comprehensive Cancer Center

Recruiting

Expedited Laser Interstitial Thermal Therapy + Chemoradiation For Newly Diagnosed High Grade Gliomas

High Grade Glioma

United States
University of Cincinnati

Completed

Radiation Planning Study for High Grade Brain Tumors

High Grade Glioma

United States
Chinese PLA General Hospital

Recruiting

A Phase ll Trial of the Combination of Zanubrutinib, Rituximab and Venetoclax in Patients With Previously Untreated Follicular Lymphoma (ZARAV)

Ann Arbor Stage II Follicular Lymphoma | Ann Arbor Stage III Follicular Lymphoma | Ann Arbor Stage IV Follicular Lymphoma | Grade 1 Follicular Lymphoma | Grade 2 Follicular Lymphoma | Grade 3a Follicular Lymphoma

China
Daniel Morgenstern
The Hospital for Sick Children

Recruiting

Pilot Study of Vinblastine and Tovorafenib in Pediatric Patients With Recurrent/Progressive RAF Altered Low Grade Gliomas (VICTORY)

Low-grade Glioma

Canada
University of Alabama at Birmingham

Recruiting

Multiparametic Metabolic and Hypoxic PET/MRI for Disease Assessment in High Grade Glioma

High Grade Glioma

United States
Weiguo Zhang

Recruiting

How the Precise Habitats Can Predict the IDH Mutation Status and Prognosis of the Patients With High-grade Gliomas

High-grade Glioma

China
Laminar Pharmaceuticals
Dana-Farber Cancer Institute; Hackensack Meridian Health; Laminar Pharma Inc

Recruiting

Study of LAM561 Acid in Pediatric Patients With Malignant Glioma and Other Advanced Solid Tumors

High-grade Glioma | Solid Tumor, Unspecified, Child

United States
Nationwide Children's Hospital

Not yet recruiting

Intra-tumoral Injection of Natural Killer Cells in High-Grade Gliomas (NK HGG)

High Grade Glioma

United States
James Felker
National Cancer Institute (NCI); Connor's Cure

Recruiting

A Vaccine Trial for Low Grade Gliomas

Low Grade Glioma

United States
WPD Pharmaceuticals Sp. z o.o.
Worldwide Clinical Trials

Withdrawn

A Multicenter, Study of the Safety and Pharmacokinetics of Intravenously Infused Berubicin in Pediatric Patients With Progressive, Refractory, or Recurrent High Grade Gliomas

High Grade Glioma
University of California, San Francisco
National Cancer Institute (NCI); Ipsen

Completed

Study of Convection-Enhanced, Image-Assisted Delivery of Liposomal-Irinotecan In Recurrent High Grade Glioma

High Grade Glioma

United States
University Hospital, Basel, Switzerland
University Basel, Department of Sport, Exercise and Health, Division of Sport...

Completed

Glioma and Exercising

High Grade Glioma

Switzerland
Centre Oscar Lambret
National Cancer Institute, France; Pierre Fabre Laboratories

Completed

Phase II Trial of Oral Vinorelbine in Children With Recurrent or Progressive Unresectable Low-Grade Glioma (OVIMA-1210)

Low-Grade Glioma

France
Tata Memorial Hospital
Terry Fox Foundation

Unknown

SCRT Versus Conventional RT in Children and Young Adults With Low Grade and Benign Brain Tumors (SCRT)

Craniopharyngioma | Meningiomas | Ependymomas | Low Grade Gliomas

India
Beijing Sanbo Brain Hospital

Completed

Study of Recombinant Human Endostatin Combined With CV Regimen in the Treatment of Pediatric Low-grade Gliomas

Low-grade Glioma | Pediatric Brain Tumor

China
European Organisation for Research and Treatment...
Cooperative Trials Group for Neuro-Oncology (COGNO)

Terminated

Trial in Low Grade Glioma Patients: Wait or Treat (IWOT)

Temozolomide | Low-grade Glioma | Phase III | Wait or Treat

Spain, Australia, Switzerland, France, Belgium, Italy, Austria, Netherlands, United Kingdom, Denmark
St. Olavs Hospital
Norwegian University of Science and Technology

Recruiting

68Ga/177Lu-PSMA Theranostics in Recurrent Grade 3 and Grade 4 Glioma

High Grade Glioma

Norway
Central Hospital, Nancy, France

Recruiting

Contribution of Cerebral 18F-DOPA PET-CT Scan in High-grade Recurrent Gliomas (DORA)

High Grade Glioma

France
Nader Sanai
InSightec; SonALAsense, Inc.; Barrow Neurological Institute; Ivy Brain Tumor Center

Recruiting

Study of Sonodynamic Therapy in Participants With Recurrent High-Grade Glioma

High Grade Glioma

United States
The First People's Hospital of Lianyungang
The Affiliated Hospital of Qingdao University; Shandong Cancer Hospital and... and other collaborators

Unknown

Apatinib and Irinotecan in Treating Patients With Recurrent High-grade Glioma

High-grade Glioma

China
Institut Curie

Terminated

AsiDNA Children, Adolescents and Young Adults (AsiDNA)

Recurrent High-grade Glioma

France
Case Comprehensive Cancer Center

Terminated

Lenalidomide And Rituximab as Maintenance Therapy in Treating Patients With B-Cell Non-Hodgkin Lymphoma

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Diffuse Small Cleaved Cell Lymphoma and other conditions

United States
Alpheus Medical, Inc.

Active, not recruiting

Study to Evaluate 5-ALA Combined With CV01 Delivery of Ultrasound in Recurrent High Grade Glioma

High Grade Glioma

United States
University Hospital, Montpellier

Completed

Longitudinal MRI Assessment in Patients With Diffuse Low-grade Gliomas (SPECIFY)

Low-grade Glioma

France
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Ultra Low Dose Orbital Radiation Therapy in Treating Patients With Stage I-IV Indolent B-cell Lymphoma or Mantle Cell Lymphoma

Ann Arbor Stage I Grade 1 Follicular Lymphoma | Ann Arbor Stage I Grade 2 Follicular Lymphoma | Ann Arbor Stage II Grade 1 Follicular Lymphoma | Ann Arbor Stage II Grade 2 Follicular Lymphoma | Ann Arbor Stage IV B-Cell Non-Hodgkin Lymphoma | Ann Arbor Stage I B-Cell Non-Hodgkin Lymphoma | Ann... and other conditions

United States
Joseph Tuscano
National Cancer Institute (NCI); Genentech, Inc.; Pharmacyclics LLC.

Recruiting

Obinutuzumab, Ibrutinib, and Venetoclax for the Treatment of Previously Untreated Stage II-IV Follicular Lymphoma

Ann Arbor Stage II Follicular Lymphoma | Ann Arbor Stage III Follicular Lymphoma | Ann Arbor Stage IV Follicular Lymphoma | Grade 1 Follicular Lymphoma | Grade 2 Follicular Lymphoma | Grade 3a Follicular Lymphoma

United States
National Cancer Institute (NCI)

Active, not recruiting

Telaglenastat With Radiation Therapy and Temozolomide in Treating Patients With IDH-Mutated Diffuse Astrocytoma or Anaplastic Astrocytoma

Astrocytoma, IDH-Mutant, Grade 2 | Astrocytoma, IDH-Mutant, Grade 3

United States
Massachusetts General Hospital
GlaxoSmithKline

Recruiting

Niraparib In Recurrent IDH 1/2 Gliomas

Recurrent Glioma | Low-grade Glioma | Glioma, Malignant | IDH2 Gene Mutation | IDH1 Mutation

United States
Duke University

Not yet recruiting

Open-Label Study to Evaluate the Safety, Tolerability and Efficacy of the Oncolytic HSV1 MVR-C5252 (PuMP)

Recurrent High Grade Glioma
Duke University
Genentech, Inc.

Completed

Bevacizumab Beyond Progression (BBP) (BBP)

Glioblastoma | Malignant Glioma | Gliosarcoma | Grade 4 Malignant Glioma

United States
Northwest Biotherapeutics

Active, not recruiting

Study of a Drug [DCVax®-L] to Treat Newly Diagnosed GBM Brain Cancer (GBM)

Glioma | Glioblastoma | Brain Cancer | Brain Tumor | Glioblastoma Multiforme | GBM | Grade IV Astrocytoma

United States, Germany, Canada, United Kingdom
Samus Therapeutics, Inc.

Terminated

Study of Icapamespib (PU-AD) in Patients With Recurrent Malignant Glioma (Glio)

Recurrent Glioblastoma Multiforme (GBM) | Grade 3 Isocitrate Dehydrogenase (IDH) Wildtype Astrocytoma | Grade 3 or 4 Astrocytoma | Glioblastoma Surgery

United States
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI); American Lebanese Syrian Associated Charities...

Recruiting

A Trial of Dabrafenib, Trametinib and Hydroxychloroquine for Patients With Recurrent LGG or HGG With a BRAF Aberration

Low Grade Glioma (LGG) of Brain With BRAF Aberration | High Grade Glioma (HGG) of the Brain With BRAF Aberration | Low Grade Glioma of Brain With Neurofibromatosis Type 1

United States
Children's Hospital Los Angeles
Dana-Farber Cancer Institute

Active, not recruiting

Study of MEK162 for Children With Low-Grade Gliomas

Soft Tissue Neoplasms | Low-Grade Gliomas | Malignant Neoplasms, Brain

United States
National Cancer Institute (NCI)

Completed

FAU in Treating Patients With Advanced Solid Tumors or Lymphoma

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Diffuse Small Cleaved Cell Lymphoma and other conditions

United States
National Cancer Institute (NCI)

Terminated

Oblimersen and Gemcitabine in Treating Patients With Advanced Solid Tumor or Lymphoma

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Diffuse Small Cleaved Cell Lymphoma and other conditions

United States
National Cancer Institute (NCI)

Completed

Sorafenib in Treating Patients With Metastatic or Unresectable Solid Tumors, Multiple Myeloma, or Non-Hodgkin's Lymphoma With or Without Impaired Liver or Kidney Function

Stage II Multiple Myeloma | Stage III Multiple Myeloma | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma and other conditions

United States
Case Comprehensive Cancer Center
Burkhardt Brain Tumor and Neuro-Oncology Center

Recruiting

Prospective Surgical Study on the Pattern of Electrical Activity in High Grade Glioma as a Predictor of Progression

Glioblastoma | High Grade Glioma

United States
Sunnybrook Health Sciences Centre
Canadian Institutes of Health Research (CIHR); Sunnybrook Research Institute

Recruiting

Glioma Supra Marginal Incision Trial (G-SUMIT)

High Grade Glioma

Canada, United States
CCTU- Cancer Theme
Cambridge University Hospitals NHS Foundation Trust; Cancer Research UK; Experimental...

Active, not recruiting

Predicting Sites of Tumour Progression in the Invasive Margin of Glioblastomas (PRaM-GBM Study) (PRaM-GBM)

High Grade Glioma

United Kingdom

Clinical Trials on WHO Grade IV Gliomas

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