Clinical Trials on Xerostomia Due to Hyposecretion of Salivary Gland

Total 777 results

University Hospital, Limoges

Completed

Neurotrophins Implications in Primary Sjögren Syndrome (Neuro-SGSp)

Primary Sjögren Syndrome

France
IRCCS Azienda Ospedaliero-Universitaria di Bologna

Completed

Cord Blood Serum in the Treatment of Ocular Surface Diseases

Graft vs Host Disease | Sjogren's Disease

Italy
TorreyPines Therapeutics

Completed

Study of NGX267 Oral Capsules in Patients With Xerostomia Associated With Sjorgren's Syndrome

Sjogren's Syndrome | Xerostomia

United States
National Institute of Dental and Craniofacial Research...

Completed

Potential of Transplanted Stem Cells to Mature Into Salivary Gland and Cheek Cells

Sjogren's Syndrome | Graft vs Host Disease

United States
Stanford University
National Cancer Institute (NCI); Agennix

Terminated

Talactoferrin in Treating Patients With Relapsed or Refractory Non-Small Cell Lung Cancer or Squamous Cell Head and Neck Cancer

Tongue Cancer | Recurrent Metastatic Squamous Neck Cancer With Occult Primary | Recurrent Salivary Gland Cancer | Recurrent Squamous Cell Carcinoma of the Hypopharynx | Recurrent Squamous Cell Carcinoma of the Larynx | Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity | Recurrent Squamous... and other conditions

United States
University of Pisa

Recruiting

Ultra-High Frequency Ultrasonography in Sjögren's Syndrome (UltraSjögren)

Sjogren's Syndrome

Italy
University Tunis El Manar

Not yet recruiting

EVADRY® in the Treatment of Xerostomia in Sjögren's Syndrome (DRYLESS)

Sjogren's Syndrome
Amgen

Recruiting

A Phase 2 Study to Investigate Efficacy and Safety of HZN-1116 in Participants With Sjogren's Syndrome

Sjogren's Syndrome

United States
Amgen

Recruiting

A Study to Evaluate the Efficacy and Safety of Dazodalibep in Participants With Sjögren's Syndrome (SS) With Moderate-to-severe Systemic Disease Activity

Sjogren's Syndrome

United States, Argentina, Japan
Zhejiang University
Yake Biotechnology Ltd.

Recruiting

A Study of CD19/BCMA Chimeric Antigen Receptor T Cells Therapy for Patients With Refractory Sjogren's Syndrome

Autoimmune Diseases | Sjogren's Syndrome

China
Centre Hospitalier Universitaire de Nīmes

Recruiting

Descriptive Study of Variations in Serum Translocation Markers of the Intestinal Microbiota in Patients With Gougerot-Sjögren Syndrome According to Disease Activity (IMISS)

Sjogren's Syndrome

France
University of Sao Paulo General Hospital

Active, not recruiting

Immune Profile of Saliva and Serum of Patients With Primary Sjögren´s Syndrome (pSS)

Sjogren's Syndrome

Brazil
Peking Union Medical College Hospital

Completed

A Prospective Pilot Study to Explore Efficacy and Safety of Baricitinib in Active Primary Sjogren's Syndrome Patients

Sjogren's Syndrome

China
Otsuka Pharmaceutical Co., Ltd.

Completed

Exploratory Study for Dry Mouth in Patients With Sjögren's Syndrome

Sjogren's Syndrome | Xerostomia

Japan
Northumbria University
Newcastle University; Versus Arthritis; Teesside University

Unknown

Pilot Feasibility Study of a Sjögren's Syndrome Self-management App

Sjogren's Syndrome

United Kingdom
Cairo University

Completed

Probiotics as a Prophylaxis to Prevent Clinical Manifestations of Oral Candidosis in Patients With Sjogren's Syndrome

Sjogren's Syndrome

Egypt
Hoffmann-La Roche

Completed

A Study to Assess the Efficacy of RO5459072 in Participants With Primary Sjogren's Syndrome

Sjogren's Syndrome

United States, United Kingdom, Poland, Germany, Portugal, France
Samira Tatiyama Miyamoto
Federal University of São Paulo; Newcastle University

Completed

Aerobic Exercise in Primary Sjögren's Syndrome (AEPSS)

Sjogren's Syndrome

Brazil
National Institute of Dental and Craniofacial Research...

Completed

The Functioning of Immune and Hormonal Systems in Patients With Sjogren's Syndrome and in Healthy Volunteers

Sjogren's Syndrome

United States
National Institute of Dental and Craniofacial Research...

Completed

Pilot Study of Thalidomide to Treat Sjogren's Syndrome

Sjogren's Syndrome | Xerostomia

United States
National Cancer Institute (NCI)

Terminated

Sunitinib, Cetuximab, and Radiation Therapy in Treating Patients With Locally Advanced or Recurrent Squamous Cell Carcinoma of the Head and Neck

Tongue Cancer | Recurrent Metastatic Squamous Neck Cancer With Occult Primary | Recurrent Salivary Gland Cancer | Recurrent Squamous Cell Carcinoma of the Hypopharynx | Recurrent Squamous Cell Carcinoma of the Larynx | Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity | Recurrent Squamous... and other conditions

United States
Saglik Bilimleri Universitesi

Completed

The Effect of Chewing Gum, Exercises of the Tongue, Lip, Jaw on Salivation, Xerostomia, Dysphagia in Sjögren's Syndrome (SS)

Dysphagia | Xerostomia | Sjögren's Syndrome | Salivary Flow Rate

Turkey
Douglas Mental Health University Institute
McGill University; Weston Brain Institute

Completed

Dosage and Efficacy of Probucol-induced apoE to Negate Cognitive Deterioration (DEPEND)

Mild Cognitive Impairment Due to Alzheimer Disease | Age-related Cognitive Decline | Dementia of the Alzheimer Type

Canada
University of British Columbia
Vancouver Coastal Health Research Institute; Genome British Columbia

Recruiting

Advancing Cardiac Care Unit-based Rapid Assessment and Treatment of hypErcholesterolemia (ACCURATE)

Acute Coronary Syndrome | Familial Hypercholesterolemia | STEMI | NSTEMI - Non-ST Segment Elevation MI | Familial Hypercholesterolemia - Heterozygous | Familial Hypercholesterolemia Due to Genetic Defect of Apolipoprotein B | Familial Hypercholesterolemia Due to Heterozygous LDL Receptor Mutation and other conditions

Canada
KTO Karatay University
Selcuk University; Nigde Omer Halisdemir University

Not yet recruiting

Effect of Kinesio Tape on Back Pain, Breastfeeding Success and Breastfeeding Self-Efficacy

Mothers Who Have Babies Between 0-6 Months and Are Actively Breastfeeding | Mothers Who Complain of Back Pain Due to Breastfeeding (Getting 6 Points or More on VAS in the Mothers' Own Evaluation)
AnGes USA, Inc.

Recruiting

Study of AMG0001 to Improve Ulcer Healing and Perfusion in Subjects With Peripheral Ischemic Ulcers

Peripheral Artery Disease | Chronic Limb Threatening Ischemia | Ischaemic Ulcer of Lower Leg Due to Atherosclerotic Disease | Ischemic Ulcer of Foot

United States
Medical University of Lublin

Completed

Clinical Outcomes of Implantationof Black Diaphragm Intraocular Lens in Complete Aniridia and Aphakia Due to Posttraumatic Eye Rupture

Aniridia | Aphakia Due to Trauma | Eye; Rupture, Traumatic, With Loss of Intraocular Tissue

Poland
Medical University of Vienna

Completed

Cerebral Microembolism During Hemodialysis

Cerebral Embolism | Complication of Dialysis | Thrombus Due to Renal Dialysis Device, Implant, or Graft

Austria
National Cancer Institute (NCI)

Completed

Cediranib Maleate in Treating Patients With Recurrent or Newly Diagnosed Metastatic Head and Neck Cancer

Recurrent Hypopharyngeal Squamous Cell Carcinoma | Recurrent Laryngeal Squamous Cell Carcinoma | Recurrent Oropharyngeal Squamous Cell Carcinoma | Salivary Gland Squamous Cell Carcinoma | Recurrent Lip and Oral Cavity Squamous Cell Carcinoma | Recurrent Nasopharyngeal Keratinizing Squamous... and other conditions

United States
Sohag University

Completed

Correlation Between Micro Vascular Complications and Severity of Coronary Artery Disease in Type 2 DM

Patients With Type 2 DM Who Underwent Coronary Angiography Due to Coronary Artery Disease and Presence of Microvascular Complications in Same Patients

Egypt
Bionorica SE

Completed

BX-1 in Spasticity Due to Multiple Sclerosis

Spasticity Due to Multiple Sclerosis

Hungary, Czechia, Germany, Poland, Spain
University of Pittsburgh
Emory University

Completed

Pathogenesis of Functional Hypothalamic Amenorrhea

Stress, Psychological | Metabolic Disturbance | Disorder of Endocrine Ovary | Hypersecretion; Cortisol

United States
Rise Therapeutics LLC

Not yet recruiting

R-2487 in Patients With Sjogren's Syndrome (SS) (R-2487-SS-01)

Sjogren's Syndrome | Sjögren | Sjögren Syndrome, Unspecified
University Hospital, Brest

Recruiting

Diagnostic Suspicion of Primitive Syndrome Sjögren's : Brest Cohort (DIApSS)

Primary Sjögren's Syndrome (pSS)

France
Centre Hospitalier Universitaire de Saint Etienne
Ministry of Health, France

Recruiting

Autoreactive Anti-Ro/SSA IgE To Determine Primary SjögRen's Syndrome's Disease Activity (I GET DRY)

Primary Sjögren's Syndrome

France
Institut de Recherches Internationales Servier
ADIR, a Servier Group company

Completed

Efficacy and Safety of S95011 in Primary Sjögren's Syndrome Patients

Primary Sjögren's Syndrome

United States, France, United Kingdom, Australia, Germany, Hungary, Spain
Samjin Pharmaceutical Co., Ltd.

Completed

Clinical Study to Investigate the Efficacy of Orally Administered SA001 in Patients With Primary Sjögren's Syndrome

Primary Sjögren's Syndrome (pSS)

Korea, Republic of
Novartis Pharmaceuticals

Terminated

A Phase 2 Study to Evaluate the Safety and Efficacy of LOU064 in Patients With Moderate to Severe Sjögren's Syndrome (LOUiSSe)

Sjögren Syndrome

Spain, United States, Belgium, Hungary, Germany, Switzerland, Australia, Denmark, China, Taiwan, United Kingdom, Bulgaria
Tianjin Eye Hospital

Completed

HRR as a Novel Biomarker in Sjögren's Syndrome

Sjögren's Syndrome

China
AbbVie

Withdrawn

An Efficacy and Safety Study of Injectable Ravagalimab to Assess Change in EULAR Sjogren's Syndrome Disease Activity Index (ESSDAI) in Adult Participants With Moderately to Severely Active Primary Sjogren's Syndrome (pSS)

Sjogren's Syndrome (SS)

Netherlands
University College, London

Completed

SS-INQ Information Needs Questionnaire in Sjögren's Syndrome (SS-INQ)

Sjögren's Syndrome

United Kingdom
Novartis Pharmaceuticals

Completed

PD of VAY736 in Patients With Primary Sjögren's Syndrome (CVAY736X2201)

Primary Sjögren's Syndrome

Germany
Incyte Corporation

Completed

A Study of INCB050465 in Primary Sjögren's Syndrome

Primary Sjögren's Syndrome

United States
Hospital Hietzing

Completed

Effect of Ciclosporin Eyedrops on Sjögren Syndrome

Dry Eye Syndromes

Austria
Ankara Education and Research Hospital

Completed

Effects of Primary Sjögren's Syndrome on Female Genitalia and Sexual Functions

Primary Sjögren Syndrome

Turkey
Novartis Pharmaceuticals

Completed

Safety, Pharmacokinetics and Preliminary Efficacy Study of CFZ533 in Patients With Primary Sjögren's Syndrome

Primary Sjögren's Syndrome

United States, Hungary, Germany, Switzerland, United Kingdom
Chung Shan Medical University

Completed

A Clinical Trial to Evaluate the Safety and Efficacy of Traditional Chinese Medicine in Sjögren's Syndrome.

Sjögren's Syndrome

Taiwan
University Hospital, Brest

Unknown

Eye Dryness Evaluation in Primary Sjögren's Syndrome (PEPSS)

Primary Sjögren Syndrome
GlaxoSmithKline
Adelphi Real World

Completed

Adelphi Primary Sjogren's Syndrome (pSS) Disease Specific Programme (DSP)

Sjogren's Syndrome

United Kingdom
You First Services

Unknown

"Hyaluronan" Formulation for Dry Mouth in Sleep Apnea Patients

Sleep Apnea | OSA | Xerostomia | Dry Mouth

United States

Clinical Trials on Xerostomia Due to Hyposecretion of Salivary Gland

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Lithuania

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations