Search clinical trials for: "Usual Care"

Total 16070 results

Srinakharinwirot University
Ministry of Health, Thailand

Unknown

Curcumin Therapy in Patients With Impaired Glucose Tolerance and Insulin Resistance

Insulin Resistance | Type 2 Diabetes | Cardiovascular Risk | Pre-diabetes

Thailand
M.D. Anderson Cancer Center
Invectys

Recruiting

A Safety And Efficacy Study Of HLA-G- Targeted CAR-T Cells IVS-3001 In Subjects With Previously Treated Advanced HLA-G-Positive Solid Tumors

Solid Tumor

United States
M.D. Anderson Cancer Center

Recruiting

Phase I/II Study of CAR.70- Engineered IL15-transduced Cord Blood-derived NK Cells in Conjunction With Lymphodepleting Chemotherapy for the Management of Relapse/Refractory Hematological Malignances

B-Cell Lymphoma | Myelodysplastic Syndromes (MDS) | Acute Myeloid Leukemia (AML)

United States
National Cancer Institute (NCI)

Recruiting

Administering Peripheral Blood Lymphocytes Transduced With a CD70-Binding Chimeric Antigen Receptor to People With CD70 Expressing Cancers

Melanoma | Breast Cancer | Pancreatic Cancer | Ovarian Cancer | Renal Cell Cancer

United States
MedImmune LLC

Active, not recruiting

A Study to Evaluate MEDI5752 in Subjects With Advanced Solid Tumors

Selected Advanced Solid Tumors

Italy, Spain, United States, France, Korea, Republic of, Taiwan, Australia, Netherlands, Portugal
Costantine Albany
Hoosier Cancer Research Network; Achieve Life Sciences

Terminated

OGX-427 in Metastatic Castrate-Resistant Prostate Cancer With Prostate-Specific Antigen Progression While Receiving Abiraterone

Prostate Cancer | PSA | Metastatic Castrate-Resistant Prostate Cancer

United States, Canada
National Cancer Institute (NCI)

Completed

T-cells Expressing an Anti-SLAMF7 CAR for Treating Multiple Myeloma

Myeloma-Multiple | Myeloma, Plasma-Cell

United States
USWM, LLC (dba US WorldMeds)
National Institute on Drug Abuse (NIDA)

Completed

Single-Dose Pharmacokinetics and Safety of Oral Lofexidine in Hepatically-Impaired Subjects

Liver Failure

United States
Vertex Pharmaceuticals Incorporated

Completed

Phase 2 Study of VX-950, Pegasys® With and Without Copegus® in Hepatitis C

Chronic Hepatitis C

Austria, France, Germany, United Kingdom
Saint Francis Memorial Hospital

Completed

Chemotherapy Followed by Biological Therapy in Treating Patients With Stage IV Melanoma That Cannot be Treated With Surgery

Melanoma (Skin)

United States
National Institute of Allergy and Infectious Diseases...
ViiV Healthcare

Active, not recruiting

More Options for Children and Adolescents (MOCHA): Oral and Long-Acting Injectable Cabotegravir and Rilpivirine in HIV-Infected Children and Adolescents (MOCHA)

HIV Infections

Thailand, United States, Botswana, Uganda, South Africa
Boehringer Ingelheim

Completed

Determining Optimal Free Dose Combination of Tiotropium Bromide and BI 1744 CL in Chronic Obstructive Pulmonary Disease (COPD)

Pulmonary Disease, Chronic Obstructive

Canada, Germany, Netherlands, Sweden
Boehringer Ingelheim

Completed

Telmisartan/Amlodipine (80/5) vs. Telmisartan/Amlodipine (40/5) vs. Amlodipine 10 or 5 in Resistant Hypertension

Hypertension

Belgium, Canada, Denmark, Finland, France, Korea, Republic of, Netherlands, Norway, Philippines, South Africa, Sweden, Taiwan
University Hospital "Sestre Milosrdnice"

Completed

The Influence of Silicone Oil on Nerve Fiber Layer Thickness After Pars Plana Vitrectomy

Rhegmatogenous Retinal Detachment | Toxic Effect of Silicone | Glaucoma Due to Silicon Oil

Croatia
Yonsei University

Unknown

The Beneficial Role of Percutaneous Coronary Intervention Over Optimal Medical Therapy in Elderly Patients With Coronary Artery Disease (BRAVE)

Coronary Artery Disease

Korea, Republic of
University of Chicago

Not yet recruiting

Trial Studying Chemotherapy in Nigerian Women With Triple Negative Breast Cancer (TARMAC)

Triple Negative Breast Cancer
M.D. Anderson Cancer Center
Bellicum Pharmaceuticals

Recruiting

Phase 1 Dose Escalation and Expansion Study of TROP2 CAR Engineered IL15-transduced Cord Blood-derived NK Cells in Patients With Advanced Solid Tumors (TROPIKANA)

Solid Tumors

United States
Jennifer Crombie, MD
Merck Sharp & Dohme LLC

Recruiting

Pembro Plus CAR T-cell Therapy in R/R in PMBCL

Primary Mediastinal Large B-cell Lymphoma (PMBCL) | Primary Mediastinal Large B Cell Lymphoma | T-Cell/Histiocyte-Rich Large B-Cell Lymphoma | Primary Mediastinal Large B-Cell Lymphoma Refractory | Primary Mediastinal Large B-Cell Lymphoma Recurrent | Epstein-Barr Virus Positive Diffuse Large...

United States
Swiss Group for Clinical Cancer Research

Recruiting

Intravesical Recombinant BCG Followed by Perioperative Chemo-immunotherapy for Patients With MIBC

Bladder Cancer

Switzerland
Grupo Español de Investigación en Cáncer de Ovario
Hoffmann-La Roche; Apices Soluciones S.L.; AGO Study Group; ARCAGY/ GINECO GROUP; Multicenter Italian Trials in Ovarian cancer and gynecologic malignancies and other collaborators

Active, not recruiting

Platinum Chemotherapy Plus Paclitaxel With Bevacizumab and Atezolizumab in Metastatic Carcinoma of the Cervix (BEATcc)

Carcinoma of the Cervix, Stage IVB

Norway, Spain, France, Sweden, United States, Germany, Italy, Japan
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI)

Completed

Autologous T Cells With or Without Cyclophosphamide and Fludarabine in Treating Patients With Recurrent or Persistent Advanced Ovarian Epithelial Cancer, Primary Peritoneal Cavity Cancer, or Fallopian Tube Cancer (Fludarabine Treatment Closed as of 12/01/2009)

Ovarian Cancer | Fallopian Tube Cancer | Primary Peritoneal Cavity Cancer

United States
Northside Hospital, Inc.
Blood and Marrow Transplant Group of Georgia

Completed

Reduced Intensity Conditioning Transplant Using Haploidentical Donors

Multiple Myeloma | Hodgkin's Lymphoma | Non-Hodgkin's Lymphoma | Myelofibrosis | Chronic Lymphocytic Leukemia | Myelodysplastic Syndrome | Acute Lymphocytic Leukemia | Acute Myelogenous Leukemia | Chronic Myelogenous Leukemia | CMML

United States
The Christie NHS Foundation Trust
National Institute for Health Research, United Kingdom

Terminated

TIL Therapy in Metastatic Melanoma and IL2 Dose Assessment (METILDA)

Metastatic Melanoma

United Kingdom
National Cancer Institute (NCI)

Completed

T Cells Expressing a Fully-Human Anti-CD30 Chimeric Antigen Receptor for Treating CD30-Expressing Lymphomas

Lymphoma, Large B-Cell, Diffuse | Lymphoma, T-Cell, Peripheral | Lymphoma, Large-Cell, Anaplastic | Lymphoma, Extranodal NK-T-Cell | Enteropathy-Associated T-Cell Lymphoma

United States
South East Asia Research Collaboration with Hawaii
Thai Red Cross AIDS Research Centre; University of Hawaii; Queen Savang Vadhana...

Completed

A 72-week Randomized Clinical Trial Comparing the Safety and Efficacy of Three Initial Antiretroviral Regimens -GPO-VIR S (d4T/3TC/NVP) for 24 Weeks Followed by GPO-VIR Z (AZT/3TC/NVP) vs GPO-VIR Z vs TDF/FTC/NVP

HIV Infections

Thailand
University of California, San Diego
National Cancer Institute (NCI)

Unknown

Gefitinib and PEG-Interferon Alfa-2a in Treating Patients With Unresectable or Metastatic Skin Cancer

Non-melanomatous Skin Cancer

United States
Nevada Cancer Institute
National Institutes of Health (NIH); Schering-Plough

Terminated

5-aza-2-deoxycytidine With Pegylated Interferon-alfa 2B: A Phase I Study With Molecular Correlates

Cancer

United States
Masonic Cancer Center, University of Minnesota

Recruiting

Umbilical Cord Blood Transplantation Using a Myeloablative Preparative Regimen for Hematological Diseases

Follicular Lymphoma | Multiple Myeloma | Myelofibrosis | Lymphoblastic Lymphoma | Chronic Lymphocytic Leukemia | Lymphoplasmacytic Lymphoma | Non-Hodgkin Lymphoma | Mantle-Cell Lymphoma | Diffuse Large B Cell Lymphoma | Chronic Myelogenous Leukemia | Prolymphocytic Leukemia | Myelodysplasia | Acute Myeloid Leukemia... and other conditions

United States
Beijing Tiantan Hospital
Ministry of Science and Technology of the People's Republic of China

Active, not recruiting

Intensive Medical Therapy for High-risk Intracranial or Extracranial Atherosclerosis (INSPIRES)

Transient Ischemic Attack | Acute Stroke

China
GlaxoSmithKline
Geisinger HealthPlan

Completed

Sensor and Electronic Health Records (EHR) Integration Pilot Study

Pulmonary Disease, Chronic Obstructive

United States
Jonsson Comprehensive Cancer Center

Completed

Phase 1b/2 Trial Using Lapatinib, Everolimus and Capecitabine for Treatment of HER-2 Positive Breast Cancer With CNS Metastasis

HER2-positive Breast Cancer | Male Breast Cancer | Stage IV Breast Cancer | Recurrent Breast Cancer | Central Nervous System Metastases

United States
Ranjan Dohil
Meritage Pharma, Inc.

Completed

Use of Topical Budesonide in the Treatment of Eosinophilic Esophagitis

Eosinophilic Esophagitis

United States
University Hospital Tuebingen

Unknown

Peptide-specific Vaccination in HLA-A*02 Positive Patients With Biochemical Recurrence After Radical Prostatectomy

Recurrent Prostate Cancer
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

Allogeneic CD6 Chimeric Antigen Receptor T Regulatory Cells (CD6-CAR Tregs) for the Treatment of Patients With Chronic Graft Versus Host Disease After Allogeneic Hematopoietic Cell Transplantation

Chronic Graft Versus Host Disease | Hematologic and Lymphocytic Disorder | Steroid Refractory Graft Versus Host Disease

United States
Chongqing University Cancer Hospital
Fundamenta Therapeutics, Ltd.

Not yet recruiting

Safety, Efficacy and Pharmacokinetics of ThisCART19A in Patients With Refractory or Relapsed B Cell Lymphoma

Refractory or Relapsed B Cell Lymphoma

China
M.D. Anderson Cancer Center

Recruiting

Study of CAR.70-engineered IL15-transduced Cord Blood-derived NK Cells in Conjunction With Lymphodepleting Chemotherapy for the Management of Advanced Renal Cell Carcinoma, Mesothelioma and Osteosarcoma

Advanced Renal Cell Carcinoma | Advanced Mesothelioma | Advanced Osteosarcoma

United States
Universität Duisburg-Essen

Completed

Fenugreek Wraps in Osteoarthritis of the Knee (BoGon)

Osteoarthritis, Knee

Germany
Taro Pharmaceuticals USA

Completed

A Study Comparing Diclofenac Sodium Gel 3% to Solaraze® Gel 3% in the Treatment of Actinic Keratosis

Actinic Keratosis
BeiGene

Recruiting

Efficacy, Safety, and Pharmacodynamics of Tislelizumab Monotherapy and Multiple Tislelizumab-based Immunotherapy Combinations in Participants With Resectable Non-Small Cell Lung Cancer

Non Small Cell Lung Cancer

China
AstraZeneca
The Gynecologic Oncology Group (GOG) Foundation Inc; The European Network for...

Active, not recruiting

Durvalumab With or Without Olaparib as Maintenance Therapy After First-Line Treatment of Advanced and Recurrent Endometrial Cancer (DUO-E)

Endometrial Neoplasms

United States, Belgium, Canada, Germany, Korea, Republic of, Brazil, Hungary, Japan, Poland, Russian Federation, China, Hong Kong, Spain, Israel, Australia, India, Singapore, Greece, Estonia, Lithuania, Mexico, Colombia
Klinik Hirslanden, Zurich

Unknown

Non-invasive Continuous Total Hemoglobin Measurement by Pulse CO-Oximetry (SpHb)

Transcutaneous Continuous Hemoglobin Measurement
Wiseman Research Initiatives LLC

Terminated

Vaccine Therapy in Treating Patients With HER2/Neu Positive or Negative Stage IV Breast Cancer or Other HER2/Neu Positive Cancers

Breast Cancer | Unspecified Adult Solid Tumor, Protocol Specific

United States
Assiut University

Unknown

Steroids In The Management Of Acute Asthma Exacerbations In Children, Which Form Is More Suitable?

Steroids In Management Of Acute Asthma Exacerbations

Egypt
Jonsson Comprehensive Cancer Center
Parker Institute for Cancer Immunotherapy

Recruiting

Modified Immune Cells (CD19/CD20 CAR-T Cells) in Treating Patients With Recurrent or Refractory B-Cell Lymphoma or Chronic Lymphocytic Leukemia

Recurrent Mantle Cell Lymphoma | Recurrent Small Lymphocytic Lymphoma | Recurrent Diffuse Large B-Cell Lymphoma | Refractory Diffuse Large B-Cell Lymphoma | Refractory Chronic Lymphocytic Leukemia | CD20 Positive | Refractory Mantle Cell Lymphoma | Recurrent Chronic Lymphocytic Leukemia | Refractory... and other conditions

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

CD19-Car T Cell Therapy for the Treatment of Older Adults With Acute Lymphoblastic Leukemia in First Remission

B Acute Lymphoblastic Leukemia

United States
Masonic Cancer Center, University of Minnesota

Completed

Nivolumab and Oral Cyclophosphamide for R/R AML and HIgh Risk MDS

Acute Myeloid Leukemia | Higher Risk Myelodysplastic Syndrome

United States
Abbott Medical Devices

Completed

Clinical Evaluation Of Remote Monitoring With Direct Alerts To Reduce Time From Event To Clinical Decision (REACT)

The Patient Meets ACC/AHA/ESC Guidelines for Implantable Cardioverter Defibrillator (ICD) or Cardiac Resynchronization Therapy (CRT-D) Device

United Kingdom, Germany
Janssen Pharmaceutical K.K.

Completed

A Study of Abiraterone Acetate in Metastatic Castration-Resistant Prostate Cancer Participants Who Responded Poorly to the First-line Combined Androgen Blockade Therapy

Metastatic Castration-Resistant Prostate Cancer

Japan
Shahid Beheshti University of Medical Sciences
Masih Daneshvari Hospital

Unknown

Effect of Acetazolamide on Central Sleep Apnea Related to Opium Consumption

Central Sleep Apnea, Secondary

Iran, Islamic Republic of
Hoffmann-La Roche

Completed

An Observational Study of MabThera (Rituximab) in Patients With Rheumatoid Arthritis And Inadequate Response Or Intolerance to a First Anti-TNF Alpha Therapy

Rheumatoid Arthritis

Korea, Republic of

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